full name
SIN3 transcription regulator family member A

synonyms
SIN3A, ENSG00000169375

HGNC
HGNC:19353

Entrez Gene
Gene:25942

ENSEMBL
ENSG00000169375

location
chr: 15
start: 75661720
stop: 75748181
strand: -

OMIM
OMIM:607776: SIN3A
OMIM:613406: Witteveen-Kolk syndrome

transcripts
NM_001145357.1
NM_001145358.1
NM_015477.2

pathways
C-MYB transcription factor network [NCBI:138073] [Pathway Interaction Database:cmyb_pathway] [PUBMED:17152050] [PUBMED:1944282] [PUBMED:7964503] [PUBMED:8598284] [PUBMED:15608679] [PUBMED:10619021] [PUBMED:2233716] [PUBMED:9244354] [PUBMED:8654374] [PUBMED:10590070] [PUBMED:17587615] [PUBMED:12424255] [PUBMED:1679531] [PUBMED:17077080] [PUBMED:8946914] [PUBMED:16055116] [PUBMED:11259163] [PUBMED:9659917] [PUBMED:9135152] [PUBMED:7721782] [PUBMED:11290610] [PUBMED:12244173] [PUBMED:11792321] [PUBMED:17242210] [PUBMED:10722757] [PUBMED:8264615] [PUBMED:15687240] [PUBMED:14761981] [PUBMED:10542314] [PUBMED:12673198] [PUBMED:11779867] [PUBMED:8756344] [PUBMED:11427482] [PUBMED:9809063] [PUBMED:10523863] [PUBMED:11094072] [PUBMED:15356292] [PUBMED:11781241] [PUBMED:15778089] [PUBMED:9096387] [PUBMED:17931383] [PUBMED:14576818] [PUBMED:11259170] [PUBMED:8491193] [PUBMED:11581319] [PUBMED:10644988] [PUBMED:7565722] [PUBMED:9490676] [PUBMED:9244356] [PUBMED:17641686] [PUBMED:16407849] [PUBMED:1594249] [PUBMED:17822556] [PUBMED:15867358] [PUBMED:17959653] [PUBMED:7509358] [PUBMED:11287612] [PUBMED:15082531] [PUBMED:10766162] [PUBMED:8756629] [PUBMED:11115410] [PUBMED:7684005] [PUBMED:9566892]
Epigenetic regulation of gene expression [NCBI:1269734] [REACTOME:R-HSA-212165] [PUBMED:12610534]
Factors involved in megakaryocyte development and platelet production [NCBI:1269377] [REACTOME:R-HSA-983231] [PUBMED:16856888] [PUBMED:17635743] [PUBMED:17934486]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Hedgehog signaling events mediated by Gli proteins [NCBI:137912] [Pathway Interaction Database:hedgehog_glipathway] [PUBMED:14611647] [PUBMED:16908539] [PUBMED:16885213] [PUBMED:16459297] [PUBMED:15087129] [PUBMED:10075717] [PUBMED:10725236] [PUBMED:10564661] [PUBMED:15215207] [PUBMED:16611981] [PUBMED:16364285] [PUBMED:11748151] [PUBMED:16537363] [PUBMED:10531011] [PUBMED:11449277] [PUBMED:12812795] [PUBMED:16424016] [PUBMED:14723851] [PUBMED:10693759] [PUBMED:15545630] [PUBMED:16254602] [PUBMED:14603322] [PUBMED:16061793] [PUBMED:10559945] [PUBMED:16740475] [PUBMED:16705181] [PUBMED:9636069] [PUBMED:10806483] [PUBMED:11960000] [PUBMED:15930098]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Huntington's disease [NCBI:83100] [KEGG:hsa05016] [PUBMED:15336977] [PUBMED:11738471] [PUBMED:11807533] [PUBMED:15996546] [PUBMED:14526190] [PUBMED:15242639] [PUBMED:17041811] [PUBMED:15996541] [PUBMED:18951640] [PUBMED:15459747] [PUBMED:16288298] [PUBMED:17081970] [PUBMED:15695335] [PUBMED:12372277] [PUBMED:11839795]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Negative epigenetic regulation of rRNA expression [NCBI:1269737] [REACTOME:R-HSA-5250941] [PUBMED:23063748] [PUBMED:23150253] [PUBMED:18616426]
NoRC negatively regulates rRNA expression [NCBI:1269739] [REACTOME:R-HSA-427413] [PUBMED:17439825] [PUBMED:17613545] [PUBMED:23063748] [PUBMED:11583633] [PUBMED:18631128] [PUBMED:18616426]
Regulation of Telomerase [NCBI:137987] [Pathway Interaction Database:telomerasepathway] [PUBMED:12037663] [PUBMED:11191110] [PUBMED:15381700] [PUBMED:10637317] [PUBMED:15314656] [PUBMED:10601322] [PUBMED:12545159] [PUBMED:11110707] [PUBMED:15371341] [PUBMED:12681489] [PUBMED:15824061] [PUBMED:15048073] [PUBMED:10850490] [PUBMED:16730176] [PUBMED:12181313] [PUBMED:16890531] [PUBMED:9837921] [PUBMED:10224060] [PUBMED:15331176] [PUBMED:16522649] [PUBMED:9822378] [PUBMED:15316005] [PUBMED:12699629] [PUBMED:16843438] [PUBMED:12151407] [PUBMED:12135483] [PUBMED:15655249] [PUBMED:10888888] [PUBMED:16765199] [PUBMED:16869756] [PUBMED:10837221] [PUBMED:16135795] [PUBMED:11074006] [PUBMED:11191109] [PUBMED:14712220] [PUBMED:16508638] [PUBMED:10471503] [PUBMED:11854288] [PUBMED:16785237] [PUBMED:9130722] [PUBMED:12956959] [PUBMED:15710386] [PUBMED:12586360] [PUBMED:12377759] [PUBMED:11433024] [PUBMED:15843522] [PUBMED:14749375] [PUBMED:11274138] [PUBMED:12676087] [PUBMED:16166375] [PUBMED:15371412]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
Regulation of nuclear SMAD2/3 signaling [NCBI:137963] [Pathway Interaction Database:smad2_3nuclearpathway] [PUBMED:15009097] [PUBMED:11790301] [PUBMED:11836524] [PUBMED:10995736] [PUBMED:11114293] [PUBMED:10973944] [PUBMED:10022869] [PUBMED:11058129] [PUBMED:9722503] [PUBMED:12904571] [PUBMED:14993291] [PUBMED:11013220] [PUBMED:15363409] [PUBMED:9702197] [PUBMED:12718878] [PUBMED:11331591] [PUBMED:12167862] [PUBMED:14729983] [PUBMED:9707553] [PUBMED:10878024] [PUBMED:9679060] [PUBMED:10887155] [PUBMED:10199400] [PUBMED:12631740] [PUBMED:11555647] [PUBMED:15688032] [PUBMED:12150994] [PUBMED:12374795] [PUBMED:9606191] [PUBMED:9702198] [PUBMED:10518526] [PUBMED:10575014] [PUBMED:10485843] [PUBMED:11283614] [PUBMED:10722728] [PUBMED:10037600] [PUBMED:15241418] [PUBMED:14691252] [PUBMED:10748032] [PUBMED:12551947] [PUBMED:14671321] [PUBMED:11427533] [PUBMED:11711431] [PUBMED:10531362] [PUBMED:11571228] [PUBMED:10085140] [PUBMED:17478422] [PUBMED:15044954] [PUBMED:10964912] [PUBMED:11707452] [PUBMED:11801598] [PUBMED:17074756] [PUBMED:12226080] [PUBMED:10557285] [PUBMED:10843994] [PUBMED:15084259] [PUBMED:10531062] [PUBMED:16959612] [PUBMED:9679056] [PUBMED:10652350] [PUBMED:9618481] [PUBMED:11927558] [PUBMED:9732876]
Signaling events mediated by HDAC Class I [NCBI:137997] [Pathway Interaction Database:hdac_classi_pathway] [PUBMED:9885572] [PUBMED:14701748] [PUBMED:10888618] [PUBMED:12393750] [PUBMED:9804427] [PUBMED:9139820] [PUBMED:12408818] [PUBMED:16809764] [PUBMED:12788099] [PUBMED:11533489] [PUBMED:15831498] [PUBMED:15701600] [PUBMED:11532945] [PUBMED:12183469] [PUBMED:16428440] [PUBMED:9150134] [PUBMED:12972430] [PUBMED:11486036] [PUBMED:15920470] [PUBMED:9150135] [PUBMED:9651585] [PUBMED:11960997] [PUBMED:9326634] [PUBMED:11278251] [PUBMED:14521922] [PUBMED:9197243] [PUBMED:9346952] [PUBMED:16371367] [PUBMED:10444591] [PUBMED:15653507] [PUBMED:15920471] [PUBMED:11919195]
Thyroid hormone signaling pathway [NCBI:946598] [KEGG:hsa04919] [PUBMED:20005976] [PUBMED:17983645] [PUBMED:15345678] [PUBMED:16951130] [PUBMED:16214361] [PUBMED:18329679] [PUBMED:20051527] [PUBMED:17574003] [PUBMED:19716314] [PUBMED:19755667] [PUBMED:20868274] [PUBMED:21835053] [PUBMED:16051672] [PUBMED:19295177] [PUBMED:23021374] [PUBMED:22484490]
Transcriptional misregulation in cancer [NCBI:523016] [KEGG:hsa05202] [PUBMED:17327229] [PUBMED:20190806] [PUBMED:20145147] [PUBMED:11313274] [PUBMED:11863357] [PUBMED:19472090] [PUBMED:18330902] [PUBMED:19738075] [PUBMED:15024077] [PUBMED:12032780] [PUBMED:14630078] [PUBMED:21765642] [PUBMED:19564705] [PUBMED:17101797] [PUBMED:15160934] [PUBMED:15688424] [PUBMED:15985538] [PUBMED:12527902] [PUBMED:12511414] [PUBMED:11607818] [PUBMED:17222504] [PUBMED:15826838] [PUBMED:21747944] [PUBMED:19406209] [PUBMED:10350329] [PUBMED:21779514] [PUBMED:18563191] [PUBMED:16946003] [PUBMED:17250957] [PUBMED:12670461] [PUBMED:12529654] [PUBMED:18855877] [PUBMED:17505060] [PUBMED:20153925] [PUBMED:20490326] [PUBMED:12130514] [PUBMED:18648544] [PUBMED:19855079] [PUBMED:10717473] [PUBMED:20478527] [PUBMED:11340171] [PUBMED:16169901] [PUBMED:14998494] [PUBMED:19233641] [PUBMED:19133982] [PUBMED:12393465] [PUBMED:19059936] [PUBMED:18172298] [PUBMED:10500199] [PUBMED:19141473] [PUBMED:10537274] [PUBMED:15156184] [PUBMED:14701735] [PUBMED:19422821] [PUBMED:21518926] [PUBMED:18850010] [PUBMED:19075677] [PUBMED:18457914] [PUBMED:12527906] [PUBMED:15644444] [PUBMED:10784387] [PUBMED:17024155] [PUBMED:19075268] [PUBMED:15826834] [PUBMED:21849159] [PUBMED:21123453] [PUBMED:20974671] [PUBMED:20863376]