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Genes
PDPK1
Gene - PDPK1
full name
3-phosphoinositide dependent protein kinase 1
synonyms
PDK1, PDPK2, PRO0461, PDPK1, ENSG00000140992
HGNC
HGNC:8816
Entrez Gene
Gene:5170
ENSEMBL
ENSG00000140992
location
chr: 16
start: 2587965
stop: 2653191
strand: +
transcripts
NM_002613.4
NM_001261816.1
NM_031268.5
pathways
AMPK signaling pathway
[NCBI:989139]
[KEGG:hsa04152]
[PUBMED:22885100]
[PUBMED:18725075]
[PUBMED:22700795]
[PUBMED:19724019]
[PUBMED:19584320]
[PUBMED:16644802]
[PUBMED:20010958]
[PUBMED:16479585]
[PUBMED:19197243]
[PUBMED:23565491]
[PUBMED:20357764]
[PUBMED:16723978]
[PUBMED:16054041]
[PUBMED:19393004]
[PUBMED:23899560]
[PUBMED:17307971]
[PUBMED:15509864]
[PUBMED:23024365]
[PUBMED:23747347]
[PUBMED:19629071]
Activation of AKT2
[NCBI:1269433]
[REACTOME:R-HSA-165158]
Activation of NMDA receptor upon glutamate binding and postsynaptic events
[NCBI:1268798]
[REACTOME:R-HSA-442755]
[PUBMED:18616423]
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Aldosterone-regulated sodium reabsorption
[NCBI:130626]
[KEGG:hsa04960]
[PUBMED:17332888]
[PUBMED:12943727]
[PUBMED:11208606]
[PUBMED:18197893]
[PUBMED:19549592]
[PUBMED:12649599]
[PUBMED:16286565]
[PUBMED:15590995]
[PUBMED:11850323]
[PUBMED:17309947]
[PUBMED:18174920]
[PUBMED:16002531]
Apoptosis
[NCBI:83060]
[KEGG:hsa04210]
[NCBI:1270262]
[REACTOME:R-HSA-109581]
[PUBMED:12189384]
[PUBMED:20533903]
[PUBMED:18208375]
[PUBMED:22429822]
[PUBMED:15218528]
[PUBMED:24769728]
[PUBMED:18023214]
[PUBMED:25526085]
[PUBMED:23070002]
[PUBMED:15654015]
[PUBMED:15601572]
[PUBMED:14561771]
[PUBMED:24278747]
[PUBMED:21914490]
[PUBMED:22465226]
[PUBMED:21145844]
[PUBMED:12838338]
[PUBMED:18238895]
[PUBMED:12949498]
[PUBMED:18304445]
[PUBMED:14737178]
[PUBMED:26231733]
[PUBMED:9916983]
[PUBMED:14634621]
[PUBMED:19770840]
[PUBMED:22075987]
[PUBMED:4561027]
[PUBMED:20075940]
[PUBMED:9894605]
[PUBMED:26615431]
[PUBMED:12505355]
[PUBMED:11520933]
[PUBMED:19148180]
[PUBMED:16397578]
[PUBMED:15719025]
[PUBMED:15322527]
[PUBMED:15725726]
[PUBMED:12209154]
[PUBMED:23803157]
Autophagy - animal
[NCBI:83058]
[KEGG:hsa04140]
[PUBMED:16200202]
[PUBMED:15325588]
[PUBMED:24343578]
[PUBMED:15978794]
[PUBMED:19802558]
[PUBMED:16099218]
[PUBMED:11099404]
[PUBMED:19653858]
[PUBMED:15325584]
[PUBMED:20034776]
[PUBMED:15928708]
[PUBMED:21801009]
[PUBMED:25948417]
[PUBMED:16125113]
[PUBMED:21187343]
BCR signaling pathway
[NCBI:138058]
[Pathway Interaction Database:bcr_5pathway]
[PUBMED:7687428]
[PUBMED:16200195]
[PUBMED:12730099]
[PUBMED:10770799]
[PUBMED:14563325]
[PUBMED:9763608]
[PUBMED:15541657]
[PUBMED:11781242]
[PUBMED:11102801]
[PUBMED:9586640]
[PUBMED:11279148]
[PUBMED:7499277]
[PUBMED:7542197]
[PUBMED:9820480]
[PUBMED:9221755]
[PUBMED:11909947]
[PUBMED:9360945]
[PUBMED:9058799]
[PUBMED:10339589]
[PUBMED:11226282]
[PUBMED:9271416]
[PUBMED:9620684]
[PUBMED:11163197]
[PUBMED:10820378]
[PUBMED:11356195]
[PUBMED:11080163]
[PUBMED:10755621]
[PUBMED:7717978]
[PUBMED:7618087]
[PUBMED:11577348]
[PUBMED:1279802]
[PUBMED:10640270]
[PUBMED:11356834]
[PUBMED:12867038]
[PUBMED:12780340]
[PUBMED:10430908]
[PUBMED:7528218]
C-type lectin receptors (CLRs)
[NCBI:1269303]
[REACTOME:R-HSA-5621481]
[PUBMED:19521399]
[PUBMED:24330199]
CD28 co-stimulation
[NCBI:1269178]
[REACTOME:R-HSA-389356]
[PUBMED:8649453]
[PUBMED:8609386]
[PUBMED:12165654]
CD28 dependent PI3K/Akt signaling
[NCBI:1269179]
[REACTOME:R-HSA-389357]
[PUBMED:12670391]
[PUBMED:15046602]
CLEC7A (Dectin-1) signaling
[NCBI:1269304]
[REACTOME:R-HSA-5607764]
[PUBMED:12719478]
[PUBMED:19223162]
CREB phosphorylation through the activation of Ras
[NCBI:1268801]
[REACTOME:R-HSA-442742]
[PUBMED:12819448]
CTLA4 inhibitory signaling
[NCBI:1269181]
[REACTOME:R-HSA-389513]
[PUBMED:11905831]
[PUBMED:10374692]
[PUBMED:16551244]
[PUBMED:12876557]
CXCR3-mediated signaling events
[NCBI:138011]
[Pathway Interaction Database:cxcr3pathway]
[PUBMED:15528361]
[PUBMED:16210647]
[PUBMED:9541591]
[PUBMED:16368892]
[PUBMED:9660793]
[PUBMED:17289675]
[PUBMED:16467404]
[PUBMED:18291705]
[PUBMED:18375741]
[PUBMED:15150261]
[PUBMED:9625760]
[PUBMED:18174362]
[PUBMED:11554781]
[PUBMED:12750173]
[PUBMED:12782716]
[PUBMED:11136732]
[PUBMED:11739530]
[PUBMED:18292502]
CXCR4-mediated signaling events
[NCBI:137910]
[Pathway Interaction Database:cxcr4_pathway]
[PUBMED:18799424]
[PUBMED:17537990]
[PUBMED:10881171]
[PUBMED:17675482]
[PUBMED:11157475]
[PUBMED:12077227]
[PUBMED:11544290]
[PUBMED:8752280]
[PUBMED:12535795]
[PUBMED:19380820]
[PUBMED:10952719]
[PUBMED:16230460]
[PUBMED:12682230]
[PUBMED:16503409]
[PUBMED:10644702]
[PUBMED:9722546]
[PUBMED:11784854]
[PUBMED:10491003]
[PUBMED:10521508]
[PUBMED:10606629]
[PUBMED:15615703]
[PUBMED:17568820]
[PUBMED:10753828]
[PUBMED:12519755]
[PUBMED:12032308]
[PUBMED:8752281]
[PUBMED:10570282]
[PUBMED:11369622]
[PUBMED:15728464]
[PUBMED:12590707]
[PUBMED:16038794]
[PUBMED:14662753]
[PUBMED:18596232]
[PUBMED:17056591]
[PUBMED:14602072]
[PUBMED:15994292]
[PUBMED:16919488]
[PUBMED:15872091]
[PUBMED:10506573]
[PUBMED:12036857]
[PUBMED:15618472]
[PUBMED:14704365]
[PUBMED:18227351]
[PUBMED:11641392]
[PUBMED:18319399]
[PUBMED:12133960]
[PUBMED:15630457]
Choline metabolism in cancer
[NCBI:1059539]
[KEGG:hsa05231]
[PUBMED:23076158]
[PUBMED:19264150]
[PUBMED:16230400]
[PUBMED:23350810]
[PUBMED:22429397]
[PUBMED:16432178]
[PUBMED:19136975]
[PUBMED:22089420]
[PUBMED:14517341]
[PUBMED:22921309]
[PUBMED:19855431]
[PUBMED:20528734]
[PUBMED:19935796]
[PUBMED:14523987]
[PUBMED:21793073]
Class I PI3K signaling events
[NCBI:138022]
[Pathway Interaction Database:pi3kcipathway]
[PUBMED:9072969]
[PUBMED:15296756]
[PUBMED:12780340]
[PUBMED:11154281]
[PUBMED:9326591]
[PUBMED:10357815]
[PUBMED:10586033]
[PUBMED:9824312]
[PUBMED:11001876]
[PUBMED:9593664]
[PUBMED:10770799]
[PUBMED:9442017]
[PUBMED:8643691]
[PUBMED:7627555]
[PUBMED:11102801]
[PUBMED:9307042]
[PUBMED:10506192]
[PUBMED:11804589]
[PUBMED:15879121]
[PUBMED:11226282]
[PUBMED:18024423]
[PUBMED:8629002]
[PUBMED:9550703]
[PUBMED:14688341]
[PUBMED:16418224]
[PUBMED:8945478]
[PUBMED:10333475]
[PUBMED:10764758]
[PUBMED:9417041]
[PUBMED:8052307]
Class I PI3K signaling events mediated by Akt
[NCBI:138020]
[Pathway Interaction Database:pi3kciaktpathway]
[PUBMED:10102273]
[PUBMED:9812896]
[PUBMED:15718470]
[PUBMED:10485710]
[PUBMED:16919458]
[PUBMED:16213228]
[PUBMED:11154276]
[PUBMED:16962653]
[PUBMED:9346240]
[PUBMED:12244301]
[PUBMED:15057270]
[PUBMED:10217147]
[PUBMED:17407381]
[PUBMED:8524413]
[PUBMED:16982699]
[PUBMED:12637568]
[PUBMED:18024423]
[PUBMED:10358075]
[PUBMED:9637919]
[PUBMED:12244302]
[PUBMED:9094314]
[PUBMED:10576741]
[PUBMED:11864996]
[PUBMED:11777915]
[PUBMED:12244303]
[PUBMED:9381178]
[PUBMED:11231573]
[PUBMED:10949026]
[PUBMED:15262962]
[PUBMED:9512493]
[PUBMED:10783894]
Constitutive Signaling by AKT1 E17K in Cancer
[NCBI:1268881]
[REACTOME:R-HSA-5674400]
[PUBMED:17611497]
[PUBMED:18954143]
Costimulation by the CD28 family
[NCBI:1269177]
[REACTOME:R-HSA-388841]
[PUBMED:10374692]
[PUBMED:14647476]
[PUBMED:11905831]
DAP12 interactions
[NCBI:1269283]
[REACTOME:R-HSA-2172127]
[PUBMED:19120482]
[PUBMED:17220916]
[PUBMED:9490415]
[PUBMED:18192027]
[PUBMED:15884055]
DAP12 signaling
[NCBI:1269284]
[REACTOME:R-HSA-2424491]
[PUBMED:15884055]
[PUBMED:17110943]
[PUBMED:17220916]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
Downstream TCR signaling
[NCBI:1269176]
[REACTOME:R-HSA-202424]
[PUBMED:15084594]
Downstream signal transduction
[NCBI:1269479]
[REACTOME:R-HSA-186763]
[PUBMED:10508235]
[PUBMED:9739761]
Downstream signaling events of B Cell Receptor (BCR)
[NCBI:1269185]
[REACTOME:R-HSA-1168372]
[PUBMED:17052215]
[PUBMED:19909372]
Endometrial cancer
[NCBI:83109]
[KEGG:hsa05213]
[PUBMED:14747944]
[PUBMED:11431710]
[PUBMED:7585656]
[PUBMED:16508724]
[PUBMED:15284264]
[PUBMED:17028294]
[PUBMED:16248975]
[PUBMED:15947972]
ErbB1 downstream signaling
[NCBI:138057]
[Pathway Interaction Database:erbb1_downstream_pathway]
[PUBMED:1330321]
[PUBMED:7939666]
[PUBMED:9448004]
[PUBMED:3497813]
[PUBMED:7680434]
[PUBMED:18567582]
[PUBMED:12503606]
[PUBMED:12183455]
[PUBMED:8073291]
[PUBMED:17563371]
[PUBMED:8378775]
[PUBMED:19219045]
[PUBMED:1990291]
[PUBMED:15550174]
[PUBMED:16508002]
[PUBMED:17881733]
[PUBMED:11278353]
[PUBMED:9889102]
[PUBMED:14699061]
[PUBMED:8248196]
[PUBMED:8262053]
[PUBMED:11319218]
[PUBMED:19595761]
[PUBMED:17360704]
[PUBMED:15048123]
[PUBMED:19341767]
[PUBMED:9837959]
[PUBMED:14993287]
[PUBMED:19710016]
[PUBMED:18516090]
[PUBMED:9733714]
[PUBMED:8052307]
[PUBMED:10567369]
[PUBMED:9335504]
[PUBMED:9580112]
[PUBMED:11018520]
[PUBMED:10499589]
[PUBMED:19706684]
[PUBMED:8910287]
[PUBMED:10469645]
[PUBMED:11073940]
[PUBMED:9315636]
[PUBMED:2189103]
[PUBMED:14765121]
[PUBMED:14970219]
[PUBMED:8332195]
[PUBMED:16239230]
[PUBMED:8621729]
[PUBMED:11889038]
[PUBMED:11029289]
[PUBMED:11152283]
[PUBMED:8071311]
[PUBMED:12932319]
[PUBMED:19541618]
[PUBMED:2123453]
[PUBMED:9384584]
[PUBMED:8140422]
[PUBMED:10644690]
[PUBMED:18156174]
[PUBMED:15718470]
[PUBMED:12172553]
[PUBMED:10082559]
[PUBMED:17079732]
[PUBMED:12446727]
[PUBMED:9989263]
[PUBMED:12551925]
[PUBMED:10856237]
[PUBMED:8013650]
[PUBMED:7600581]
[PUBMED:8688081]
[PUBMED:8397445]
[PUBMED:16135787]
[PUBMED:7637810]
[PUBMED:9438848]
[PUBMED:12515821]
[PUBMED:12881422]
[PUBMED:9305638]
[PUBMED:15284024]
[PUBMED:3136398]
[PUBMED:10597268]
[PUBMED:10648629]
[PUBMED:9790194]
[PUBMED:9797479]
[PUBMED:16093354]
[PUBMED:7741752]
[PUBMED:10891480]
[PUBMED:17052213]
[PUBMED:8221888]
[PUBMED:9593664]
[PUBMED:16892053]
[PUBMED:8413226]
[PUBMED:9407138]
[PUBMED:9710644]
[PUBMED:8248197]
[PUBMED:12414794]
[PUBMED:1653949]
[PUBMED:12181570]
[PUBMED:9550702]
[PUBMED:12110590]
[PUBMED:10400627]
[PUBMED:9927426]
[PUBMED:12242303]
[PUBMED:10480933]
[PUBMED:9665134]
[PUBMED:11238956]
[PUBMED:16984645]
[PUBMED:7761091]
[PUBMED:17322878]
[PUBMED:12640115]
[PUBMED:14963038]
[PUBMED:17486115]
[PUBMED:8503013]
[PUBMED:16155590]
[PUBMED:16628218]
[PUBMED:1406636]
[PUBMED:9430728]
[PUBMED:19401591]
[PUBMED:17053785]
[PUBMED:7992057]
[PUBMED:14609431]
[PUBMED:9346240]
[PUBMED:8626780]
[PUBMED:8940018]
[PUBMED:12454019]
[PUBMED:10441128]
[PUBMED:14747473]
[PUBMED:11777939]
[PUBMED:8614832]
[PUBMED:8378774]
[PUBMED:19121340]
[PUBMED:18775988]
[PUBMED:15039778]
[PUBMED:9770464]
[PUBMED:10567531]
[PUBMED:8180183]
[PUBMED:10675331]
[PUBMED:1545823]
[PUBMED:7958858]
[PUBMED:11948693]
[PUBMED:2109185]
[PUBMED:8942998]
[PUBMED:1637333]
[PUBMED:14690430]
[PUBMED:11134016]
[PUBMED:12429840]
[PUBMED:8621573]
[PUBMED:7600582]
[PUBMED:8226933]
[PUBMED:10201527]
[PUBMED:12832467]
[PUBMED:3492494]
[PUBMED:15034142]
[PUBMED:9596579]
[PUBMED:7889942]
[PUBMED:8524316]
[PUBMED:7731720]
[PUBMED:8386592]
[PUBMED:16407412]
[PUBMED:6334806]
[PUBMED:11703925]
[PUBMED:11099046]
[PUBMED:7876145]
[PUBMED:14498832]
FAS (CD95) signaling pathway
[NCBI:138081]
[Pathway Interaction Database:faspathway]
[PUBMED:9765224]
[PUBMED:11717445]
[PUBMED:9727491]
[PUBMED:11279218]
[PUBMED:12110583]
[PUBMED:11739735]
[PUBMED:8521815]
[PUBMED:9184224]
[PUBMED:20153221]
[PUBMED:9126929]
[PUBMED:10200443]
[PUBMED:16033886]
[PUBMED:8681377]
[PUBMED:9880544]
[PUBMED:9501089]
[PUBMED:10535980]
[PUBMED:9727492]
[PUBMED:7523573]
[PUBMED:11101870]
[PUBMED:9321399]
[PUBMED:9362518]
[PUBMED:12724420]
[PUBMED:16498403]
[PUBMED:11583996]
[PUBMED:15557123]
[PUBMED:7536343]
[PUBMED:12832037]
[PUBMED:9576928]
[PUBMED:9228058]
[PUBMED:7538908]
[PUBMED:18635548]
[PUBMED:20038679]
[PUBMED:10894163]
[PUBMED:12545171]
[PUBMED:16619028]
[PUBMED:9351817]
[PUBMED:9045686]
[PUBMED:15289496]
FCERI mediated NF-kB activation
[NCBI:1269301]
[REACTOME:R-HSA-2871837]
[PUBMED:17336609]
[PUBMED:16432253]
FGF signaling pathway
[NCBI:137989]
[Pathway Interaction Database:fgf_pathway]
[PUBMED:12419216]
[PUBMED:16775459]
[PUBMED:1656221]
[PUBMED:16857743]
[PUBMED:8707855]
[PUBMED:17545628]
[PUBMED:17623664]
[PUBMED:16893902]
[PUBMED:15105428]
[PUBMED:16436388]
[PUBMED:12370824]
[PUBMED:9707175]
[PUBMED:1380001]
[PUBMED:15569927]
[PUBMED:11241670]
[PUBMED:11433297]
[PUBMED:16709412]
[PUBMED:12815057]
[PUBMED:14966081]
[PUBMED:17086194]
[PUBMED:17311277]
[PUBMED:14534538]
[PUBMED:12398894]
[PUBMED:8940113]
[PUBMED:17266935]
[PUBMED:10652257]
[PUBMED:12604616]
[PUBMED:14666721]
[PUBMED:9045692]
[PUBMED:15509650]
[PUBMED:11353842]
[PUBMED:12791257]
[PUBMED:15564375]
[PUBMED:12529371]
[PUBMED:17409417]
[PUBMED:17005551]
[PUBMED:12815619]
[PUBMED:11997436]
[PUBMED:12110689]
[PUBMED:17627937]
Fc epsilon RI signaling pathway
[NCBI:83082]
[KEGG:hsa04664]
[PUBMED:16470226]
[PUBMED:12145654]
[PUBMED:11079101]
[PUBMED:10586892]
[PUBMED:14630197]
[PUBMED:12360215]
[PUBMED:11449275]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Focal adhesion
[NCBI:83067]
[KEGG:hsa04510]
[PUBMED:10698680]
[PUBMED:15459662]
[PUBMED:14756624]
[PUBMED:11573199]
[PUBMED:12640026]
[PUBMED:15179030]
[PUBMED:15108811]
[PUBMED:15053919]
[PUBMED:11082269]
[PUBMED:15034601]
[PUBMED:12235283]
[PUBMED:14519391]
[PUBMED:11146675]
[PUBMED:11229600]
[PUBMED:15688067]
[PUBMED:14744429]
[PUBMED:11882383]
FoxO signaling pathway
[NCBI:921162]
[KEGG:hsa04068]
[PUBMED:23325358]
[PUBMED:15005655]
[PUBMED:18951090]
[PUBMED:22761423]
[PUBMED:22902436]
[PUBMED:16288288]
[PUBMED:19701188]
[PUBMED:16964248]
[PUBMED:18045156]
[PUBMED:18403263]
[PUBMED:21613825]
[PUBMED:21440011]
[PUBMED:17470511]
[PUBMED:21238503]
[PUBMED:17522590]
[PUBMED:15084259]
[PUBMED:23801966]
[PUBMED:17569704]
[PUBMED:15516968]
G beta:gamma signalling through PI3Kgamma
[NCBI:1269581]
[REACTOME:R-HSA-392451]
[PUBMED:17916723]
[PUBMED:17041586]
G-protein beta:gamma signalling
[NCBI:1269580]
[REACTOME:R-HSA-397795]
[PUBMED:18834311]
GAB1 signalosome
[NCBI:1269384]
[REACTOME:R-HSA-180292]
[PUBMED:15550174]
GPCR downstream signaling
[NCBI:1269574]
[REACTOME:R-HSA-388396]
[PUBMED:12040175]
GPVI-mediated activation cascade
[NCBI:1269357]
[REACTOME:R-HSA-114604]
[PUBMED:16102042]
[PUBMED:11943772]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
Hemostasis
[NCBI:1269340]
[REACTOME:R-HSA-109582]
Hepatitis C
[NCBI:173973]
[KEGG:hsa05160]
[PUBMED:19708811]
[PUBMED:16314558]
[PUBMED:17467654]
[PUBMED:19515018]
[PUBMED:18514579]
[PUBMED:16107833]
[PUBMED:19074178]
[PUBMED:12691459]
[PUBMED:15302943]
[PUBMED:20537953]
[PUBMED:11991644]
[PUBMED:19148799]
[PUBMED:19187070]
[PUBMED:12655344]
IGF1 pathway
[NCBI:137992]
[Pathway Interaction Database:igf1_pathway]
[PUBMED:15003536]
[PUBMED:10576742]
[PUBMED:8621590]
[PUBMED:9346240]
[PUBMED:16932738]
[PUBMED:8662827]
[PUBMED:15976035]
[PUBMED:11572799]
[PUBMED:14550766]
[PUBMED:15070696]
[PUBMED:9346905]
[PUBMED:10490655]
[PUBMED:1378290]
[PUBMED:9480911]
[PUBMED:9442079]
[PUBMED:7534289]
[PUBMED:8265614]
[PUBMED:9748296]
[PUBMED:11884618]
[PUBMED:12538620]
[PUBMED:8798417]
[PUBMED:8764099]
[PUBMED:8505282]
[PUBMED:7540132]
[PUBMED:12048182]
[PUBMED:15611085]
[PUBMED:14604996]
[PUBMED:7642582]
[PUBMED:11836447]
[PUBMED:8776723]
[PUBMED:7513703]
[PUBMED:9506989]
IGF1R signaling cascade
[NCBI:1269618]
[REACTOME:R-HSA-2428924]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
IRS-mediated signalling
[NCBI:1269431]
[REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R
[NCBI:1269620]
[REACTOME:R-HSA-2428928]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:18927274]
[PUBMED:21042815]
[PUBMED:20098959]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Insulin Pathway
[NCBI:138026]
[Pathway Interaction Database:insulin_pathway]
[PUBMED:8491186]
[PUBMED:9111325]
[PUBMED:7629070]
[PUBMED:10499514]
[PUBMED:11121405]
[PUBMED:10660596]
[PUBMED:8196603]
[PUBMED:11096081]
[PUBMED:8524328]
[PUBMED:9891043]
[PUBMED:12242347]
[PUBMED:2123524]
[PUBMED:9369444]
[PUBMED:1375946]
[PUBMED:9348199]
[PUBMED:8826975]
[PUBMED:8316835]
[PUBMED:8999839]
[PUBMED:8449939]
[PUBMED:10807907]
[PUBMED:1599438]
[PUBMED:8265614]
[PUBMED:11171109]
[PUBMED:11821390]
[PUBMED:12687004]
[PUBMED:7806540]
[PUBMED:11154281]
[PUBMED:8244979]
[PUBMED:8798417]
[PUBMED:1381348]
[PUBMED:7581368]
[PUBMED:15787604]
[PUBMED:8385105]
[PUBMED:11551902]
[PUBMED:8114695]
[PUBMED:11997497]
[PUBMED:11001060]
[PUBMED:11309621]
[PUBMED:9109420]
[PUBMED:8383963]
[PUBMED:12147684]
[PUBMED:8144662]
[PUBMED:12036959]
[PUBMED:14734537]
[PUBMED:7983051]
[PUBMED:9083103]
[PUBMED:15210700]
[PUBMED:9065430]
[PUBMED:11297536]
[PUBMED:10544179]
[PUBMED:1321126]
[PUBMED:11502760]
[PUBMED:8978681]
[PUBMED:8999972]
[PUBMED:14690593]
[PUBMED:11832334]
[PUBMED:9447983]
[PUBMED:15192089]
[PUBMED:8524413]
[PUBMED:7685165]
[PUBMED:10329736]
[PUBMED:11287630]
[PUBMED:15486046]
[PUBMED:10330191]
[PUBMED:8626723]
Insulin receptor signalling cascade
[NCBI:1269429]
[REACTOME:R-HSA-74751]
[PUBMED:9677303]
[PUBMED:11282018]
Insulin resistance
[NCBI:1272486]
[KEGG:hsa04931]
[PUBMED:17130651]
[PUBMED:20466550]
[PUBMED:16364488]
[PUBMED:12765939]
[PUBMED:15166380]
[PUBMED:7666792]
[PUBMED:16756496]
[PUBMED:23647930]
[PUBMED:10923637]
[PUBMED:17141630]
[PUBMED:9886945]
[PUBMED:8048519]
[PUBMED:18309108]
[PUBMED:15107844]
[PUBMED:20526383]
[PUBMED:22360800]
[PUBMED:16186396]
[PUBMED:22675355]
[PUBMED:22677645]
Insulin signaling pathway
[NCBI:83090]
[KEGG:hsa04910]
[PUBMED:11742412]
[PUBMED:11343120]
[PUBMED:15733744]
[PUBMED:11282018]
[PUBMED:10196204]
[PUBMED:18291668]
[PUBMED:9609110]
[PUBMED:10567225]
[PUBMED:12791379]
[PUBMED:9748166]
[PUBMED:15624019]
[PUBMED:9445476]
[PUBMED:9346240]
[PUBMED:14635525]
[PUBMED:16288289]
[PUBMED:12867054]
[PUBMED:15229476]
[PUBMED:17344645]
[PUBMED:9609111]
Integrin alphaIIb beta3 signaling
[NCBI:1269359]
[REACTOME:R-HSA-354192]
[PUBMED:10605720]
[PUBMED:14754902]
[PUBMED:17624957]
[PUBMED:16102042]
[PUBMED:15205259]
[PUBMED:10508650]
NGF signalling via TRKA from the plasma membrane
[NCBI:1269460]
[REACTOME:R-HSA-187037]
[PUBMED:11520933]
[PUBMED:12676795]
[PUBMED:10851172]
[PUBMED:10579918]
Neuronal System
[NCBI:1268763]
[REACTOME:R-HSA-112316]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
[NCBI:1268786]
[REACTOME:R-HSA-112314]
Neurotrophin signaling pathway
[NCBI:101143]
[KEGG:hsa04722]
[PUBMED:16699811]
[PUBMED:10812966]
[PUBMED:12676795]
[PUBMED:16939974]
[PUBMED:10851172]
[PUBMED:15499580]
[PUBMED:14704852]
[PUBMED:11399424]
[PUBMED:10764727]
[PUBMED:10985348]
[PUBMED:16856873]
[PUBMED:11529497]
Non-small cell lung cancer
[NCBI:83119]
[KEGG:hsa05223]
[PUBMED:11895903]
[PUBMED:21753699]
[PUBMED:23733083]
[PUBMED:11902573]
[PUBMED:19629074]
[PUBMED:12867060]
[PUBMED:22154278]
[PUBMED:10944551]
[PUBMED:16112428]
[PUBMED:15942304]
[PUBMED:12407699]
[PUBMED:15948711]
[PUBMED:18593892]
[PUBMED:23201355]
[PUBMED:21855164]
[PUBMED:12379883]
[PUBMED:17625570]
[PUBMED:12741677]
[PUBMED:22736493]
[PUBMED:21850578]
[PUBMED:16870043]
[PUBMED:16189154]
PI3K Cascade
[NCBI:1269432]
[REACTOME:R-HSA-109704]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
PI3K/AKT Signaling in Cancer
[NCBI:1268879]
[REACTOME:R-HSA-2219528]
[PUBMED:20713702]
[PUBMED:10555148]
[PUBMED:19644473]
[PUBMED:17611497]
[PUBMED:21478295]
[PUBMED:17626883]
[PUBMED:16339315]
[PUBMED:18317450]
[PUBMED:18079394]
[PUBMED:9467011]
[PUBMED:17604717]
[PUBMED:9326929]
[PUBMED:18954143]
[PUBMED:20009532]
[PUBMED:19962665]
[PUBMED:21430697]
[PUBMED:19487573]
[PUBMED:10866302]
PI3K/AKT activation
[NCBI:1269473]
[REACTOME:R-HSA-198203]
[PUBMED:10579926]
[PUBMED:12123609]
PIP3 activates AKT signaling
[NCBI:1269188]
[REACTOME:R-HSA-1257604]
PPAR signaling pathway
[NCBI:83042]
[KEGG:hsa03320]
[PUBMED:15673477]
[PUBMED:15828221]
[PUBMED:14999402]
[PUBMED:15828222]
[PUBMED:16601267]
[PUBMED:15828220]
[PUBMED:10529898]
[PUBMED:15828223]
[PUBMED:16476485]
[PUBMED:11921433]
[PUBMED:16511590]
[PUBMED:16360030]
Platelet Aggregation (Plug Formation)
[NCBI:1269358]
[REACTOME:R-HSA-76009]
[PUBMED:18174460]
[PUBMED:17585075]
Platelet activation, signaling and aggregation
[NCBI:1269350]
[REACTOME:R-HSA-76002]
[PUBMED:16543958]
[PUBMED:8704248]
[PUBMED:2018971]
[PUBMED:1672265]
[PUBMED:17059469]
[PUBMED:12681240]
[PUBMED:12411949]
[PUBMED:11511514]
Platinum drug resistance
[NCBI:1404797]
[KEGG:hsa01524]
[PUBMED:24074238]
[PUBMED:26867799]
[PUBMED:14609433]
[PUBMED:26184483]
[PUBMED:24874729]
[PUBMED:15607932]
[PUBMED:25546083]
[PUBMED:25058905]
[PUBMED:19190080]
[PUBMED:14576837]
[PUBMED:20811617]
[PUBMED:21892204]
[PUBMED:20647037]
[PUBMED:17336087]
[PUBMED:26886018]
[PUBMED:23442359]
[PUBMED:17625587]
Post NMDA receptor activation events
[NCBI:1268800]
[REACTOME:R-HSA-438064]
[PUBMED:18616423]
Prostate cancer
[NCBI:83111]
[KEGG:hsa05215]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11527574]
[PUBMED:11750244]
[PUBMED:16551847]
[PUBMED:10835690]
[PUBMED:8069858]
[PUBMED:15724144]
[PUBMED:10453277]
[PUBMED:15082523]
[PUBMED:9422516]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
RHO GTPase Effectors
[NCBI:1269509]
[REACTOME:R-HSA-195258]
[PUBMED:9694656]
[PUBMED:18066052]
[PUBMED:11018042]
[PUBMED:10470034]
[PUBMED:8702756]
[PUBMED:21730051]
[PUBMED:8571126]
[PUBMED:19513348]
[PUBMED:17244649]
[PUBMED:11145705]
[PUBMED:24128008]
[PUBMED:23716662]
[PUBMED:8617235]
[PUBMED:8543060]
[PUBMED:11804587]
[PUBMED:24969695]
[PUBMED:12635176]
[PUBMED:12778124]
[PUBMED:18006505]
[PUBMED:1660188]
[PUBMED:21351730]
[PUBMED:16507994]
[PUBMED:14595335]
[PUBMED:10072071]
[PUBMED:10591629]
[PUBMED:10753910]
[PUBMED:23875749]
[PUBMED:17151359]
[PUBMED:10652353]
[PUBMED:12221077]
[PUBMED:10559936]
[PUBMED:12783890]
[PUBMED:11948177]
[PUBMED:18237546]
[PUBMED:16079795]
[PUBMED:10924361]
[PUBMED:14514689]
[PUBMED:8107774]
[PUBMED:8756646]
[PUBMED:16979770]
[PUBMED:16636067]
[PUBMED:9751706]
[PUBMED:10619026]
[PUBMED:23444367]
[PUBMED:15546864]
[PUBMED:12473120]
[PUBMED:8816443]
[PUBMED:9199170]
[PUBMED:12514133]
[PUBMED:16762923]
[PUBMED:12110184]
[PUBMED:16431929]
[PUBMED:10975528]
[PUBMED:10940294]
[PUBMED:9535855]
[PUBMED:7559638]
[PUBMED:11162552]
[PUBMED:19737400]
[PUBMED:9988689]
[PUBMED:12732141]
[PUBMED:8798539]
[PUBMED:24914801]
[PUBMED:11689693]
[PUBMED:8769096]
[PUBMED:9368021]
RHO GTPases activate PKNs
[NCBI:1269512]
[REACTOME:R-HSA-5625740]
[PUBMED:21351730]
[PUBMED:21749319]
[PUBMED:10753910]
[PUBMED:18429822]
[PUBMED:9175763]
[PUBMED:12783890]
[PUBMED:14514689]
[PUBMED:10924361]
[PUBMED:7673228]
[PUBMED:10619026]
[PUBMED:10467162]
[PUBMED:11134534]
[PUBMED:9030526]
[PUBMED:9988689]
[PUBMED:19723632]
[PUBMED:24128008]
[PUBMED:18006505]
RSK activation
[NCBI:1268803]
[REACTOME:R-HSA-444257]
[PUBMED:18813292]
Regulation of TP53 Activity
[NCBI:1383076]
[REACTOME:R-HSA-5633007]
[PUBMED:19450511]
[PUBMED:20457558]
[PUBMED:23825024]
[PUBMED:25641576]
Regulation of TP53 Degradation
[NCBI:1383079]
[REACTOME:R-HSA-6804757]
[PUBMED:21730132]
[PUBMED:10570149]
[PUBMED:15563468]
[PUBMED:16845383]
[PUBMED:11923872]
[PUBMED:11883935]
[PUBMED:17290220]
[PUBMED:17121812]
[PUBMED:10673500]
[PUBMED:9843217]
[PUBMED:9529249]
[PUBMED:21730163]
[PUBMED:11715018]
[PUBMED:9733514]
[PUBMED:19838211]
[PUBMED:10608892]
[PUBMED:16474402]
[PUBMED:19450511]
[PUBMED:16163388]
[PUBMED:10722742]
[PUBMED:21986495]
[PUBMED:15788536]
[PUBMED:19816404]
[PUBMED:11359766]
[PUBMED:11504915]
[PUBMED:9733515]
[PUBMED:19756449]
[PUBMED:11983168]
[PUBMED:8319905]
[PUBMED:20438709]
Regulation of TP53 Expression and Degradation
[NCBI:1383077]
[REACTOME:R-HSA-6806003]
[PUBMED:11883935]
[PUBMED:11923872]
[PUBMED:19293287]
[PUBMED:23303139]
[PUBMED:17499002]
[PUBMED:15563468]
[PUBMED:17121812]
[PUBMED:21986495]
[PUBMED:15103385]
[PUBMED:9529249]
[PUBMED:21814038]
[PUBMED:19250907]
[PUBMED:8319905]
[PUBMED:7878469]
[PUBMED:12654245]
[PUBMED:16213212]
Role of LAT2/NTAL/LAB on calcium mobilization
[NCBI:1269302]
[REACTOME:R-HSA-2730905]
[PUBMED:17993265]
[PUBMED:20643813]
[PUBMED:17420272]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by EGFR
[NCBI:1269380]
[REACTOME:R-HSA-177929]
[PUBMED:10459005]
[PUBMED:10404636]
[PUBMED:12297041]
[PUBMED:15142631]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Signaling by Insulin receptor
[NCBI:1269428]
[REACTOME:R-HSA-74752]
[PUBMED:8276779]
Signaling by PDGF
[NCBI:1269478]
[REACTOME:R-HSA-186797]
[PUBMED:15207811]
[PUBMED:10508235]
[PUBMED:9739761]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]
Signaling by SCF-KIT
[NCBI:1269487]
[REACTOME:R-HSA-1433557]
[PUBMED:17350321]
[PUBMED:16483568]
[PUBMED:7688988]
[PUBMED:19540337]
[PUBMED:16475976]
[PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
[NCBI:1269617]
[REACTOME:R-HSA-2404192]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22044904]
[PUBMED:22649417]
Signaling by VEGF
[NCBI:1269480]
[REACTOME:R-HSA-194138]
[PUBMED:15585754]
[PUBMED:13678960]
[PUBMED:16336962]
[PUBMED:16835467]
Signaling by the B Cell Receptor (BCR)
[NCBI:1269183]
[REACTOME:R-HSA-983705]
[PUBMED:1702903]
[PUBMED:2011584]
[PUBMED:1081164]
[PUBMED:19065780]
[PUBMED:16849466]
[PUBMED:1375264]
[PUBMED:7538118]
[PUBMED:11901194]
[PUBMED:8580068]
[PUBMED:19249086]
[PUBMED:18596693]
[PUBMED:10648173]
[PUBMED:4589993]
[PUBMED:8163536]
[PUBMED:1376928]
[PUBMED:7688784]
[PUBMED:6335036]
[PUBMED:17052215]
[PUBMED:18818202]
[PUBMED:20206686]
[PUBMED:7592958]
[PUBMED:7524079]
[PUBMED:15489917]
[PUBMED:15509800]
[PUBMED:18187424]
[PUBMED:7927516]
[PUBMED:803528]
[PUBMED:19909372]
[PUBMED:20192804]
[PUBMED:8306975]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
[NCBI:137930]
[Pathway Interaction Database:met_pathway]
[PUBMED:10793146]
[PUBMED:8906793]
[PUBMED:11929826]
[PUBMED:10022866]
[PUBMED:11532961]
[PUBMED:12475979]
[PUBMED:1718989]
[PUBMED:1846706]
[PUBMED:10970810]
[PUBMED:10516287]
[PUBMED:12138161]
[PUBMED:11046147]
[PUBMED:18073207]
[PUBMED:12951049]
[PUBMED:15494312]
[PUBMED:9001234]
[PUBMED:11352916]
[PUBMED:11896055]
[PUBMED:9440692]
[PUBMED:8607979]
[PUBMED:12244132]
[PUBMED:11162460]
[PUBMED:11809798]
[PUBMED:9693375]
[PUBMED:14636584]
[PUBMED:17297451]
[PUBMED:17682062]
[PUBMED:19628037]
[PUBMED:11069926]
[PUBMED:18819921]
[PUBMED:16423831]
[PUBMED:10558875]
[PUBMED:16858414]
[PUBMED:10995442]
[PUBMED:20332103]
[PUBMED:11146548]
[PUBMED:18346875]
[PUBMED:17894413]
[PUBMED:9252406]
[PUBMED:17635922]
[PUBMED:11134526]
[PUBMED:2005882]
[PUBMED:19609305]
[PUBMED:8380735]
[PUBMED:16537482]
[PUBMED:10618718]
[PUBMED:9591773]
[PUBMED:12894582]
[PUBMED:9748249]
[PUBMED:11741535]
[PUBMED:17881575]
[PUBMED:10713050]
[PUBMED:1655790]
[PUBMED:11784715]
[PUBMED:10753869]
[PUBMED:10713700]
[PUBMED:11118451]
[PUBMED:16952352]
[PUBMED:15314156]
[PUBMED:19272169]
[PUBMED:12802068]
[PUBMED:17363898]
[PUBMED:7513258]
[PUBMED:1827664]
[PUBMED:2541345]
[PUBMED:8387483]
[PUBMED:16620780]
[PUBMED:11445578]
[PUBMED:10734310]
[PUBMED:16227611]
[PUBMED:12941962]
[PUBMED:15735664]
[PUBMED:19071214]
[PUBMED:7731718]
[PUBMED:19289496]
[PUBMED:11438654]
[PUBMED:11896612]
[PUBMED:11894096]
[PUBMED:11896575]
[PUBMED:7499247]
[PUBMED:12147692]
[PUBMED:11948414]
[PUBMED:19881549]
[PUBMED:19525225]
[PUBMED:14684163]
[PUBMED:17055484]
[PUBMED:9668053]
[PUBMED:10531383]
[PUBMED:9681449]
[PUBMED:1655405]
[PUBMED:12686592]
[PUBMED:19109251]
[PUBMED:10679787]
[PUBMED:9487126]
[PUBMED:9886295]
[PUBMED:12058075]
[PUBMED:15452053]
[PUBMED:9184210]
[PUBMED:10871282]
[PUBMED:17329361]
[PUBMED:2554238]
Signaling events mediated by Stem cell factor receptor (c-Kit)
[NCBI:138068]
[Pathway Interaction Database:kitpathway]
[PUBMED:12909618]
[PUBMED:10364466]
[PUBMED:10673502]
[PUBMED:15315962]
[PUBMED:12192036]
[PUBMED:12444928]
[PUBMED:15504549]
[PUBMED:8950973]
[PUBMED:11071635]
[PUBMED:12149208]
[PUBMED:11369651]
[PUBMED:9038210]
[PUBMED:10679268]
[PUBMED:15465815]
[PUBMED:10523831]
[PUBMED:8611693]
[PUBMED:15676208]
[PUBMED:11805142]
[PUBMED:10637471]
[PUBMED:9872323]
[PUBMED:11809791]
[PUBMED:11520784]
[PUBMED:12691919]
[PUBMED:10397721]
[PUBMED:15611091]
[PUBMED:12356726]
[PUBMED:9528781]
[PUBMED:1381360]
[PUBMED:9651683]
[PUBMED:10849422]
[PUBMED:9355737]
Signaling events mediated by VEGFR1 and VEGFR2
[NCBI:137940]
[Pathway Interaction Database:vegfr1_2_pathway]
[PUBMED:9398617]
[PUBMED:9405464]
[PUBMED:11494124]
[PUBMED:12963813]
[PUBMED:11756651]
[PUBMED:10744763]
[PUBMED:15060076]
[PUBMED:9600074]
[PUBMED:10376603]
[PUBMED:11425855]
[PUBMED:16337972]
[PUBMED:12154000]
[PUBMED:11978735]
[PUBMED:10692392]
[PUBMED:16763158]
[PUBMED:10361126]
[PUBMED:10748121]
[PUBMED:12598525]
[PUBMED:15026417]
[PUBMED:11948691]
[PUBMED:16966330]
[PUBMED:16835467]
[PUBMED:10409677]
[PUBMED:10908731]
[PUBMED:8903320]
[PUBMED:15962004]
[PUBMED:16633338]
[PUBMED:11387210]
[PUBMED:16839566]
[PUBMED:11312102]
[PUBMED:10207622]
[PUBMED:16787925]
[PUBMED:12171920]
[PUBMED:12509223]
[PUBMED:16760434]
[PUBMED:14724572]
[PUBMED:11704645]
[PUBMED:12821150]
[PUBMED:12881528]
[PUBMED:9790910]
[PUBMED:10376602]
[PUBMED:15247219]
[PUBMED:11333271]
[PUBMED:12214271]
[PUBMED:9804796]
[PUBMED:11986311]
[PUBMED:9182576]
[PUBMED:15217908]
[PUBMED:10749680]
[PUBMED:16763549]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
Sphingolipid signaling pathway
[NCBI:1144995]
[KEGG:hsa04071]
[PUBMED:23919551]
[PUBMED:21705677]
[PUBMED:18675379]
[PUBMED:20534702]
[PUBMED:15999095]
[PUBMED:16470226]
[PUBMED:11001563]
[PUBMED:17913601]
[PUBMED:17161984]
[PUBMED:22654878]
[PUBMED:17438574]
[PUBMED:18216770]
[PUBMED:11418646]
[PUBMED:10880336]
[PUBMED:15451787]
[PUBMED:25309325]
[PUBMED:18403224]
T cell receptor signaling pathway
[NCBI:83080]
[KEGG:hsa04660]
[PUBMED:17395537]
[PUBMED:15308211]
[PUBMED:15928679]
[PUBMED:14656980]
[PUBMED:17187070]
[PUBMED:15084594]
[PUBMED:16799472]
[PUBMED:12669022]
[PUBMED:15286727]
[PUBMED:15122199]
[PUBMED:19132916]
[PUBMED:15489916]
[PUBMED:11905831]
[PUBMED:12195013]
[PUBMED:15343367]
[PUBMED:12133805]
[PUBMED:14647476]
[PUBMED:15771581]
[PUBMED:15099566]
[PUBMED:14617194]
[PUBMED:19290929]
[PUBMED:15345216]
TCR signaling
[NCBI:1269172]
[REACTOME:R-HSA-202403]
[PUBMED:10375551]
[PUBMED:12876557]
[PUBMED:9989491]
TCR signaling in naive CD4+ T cells
[NCBI:137998]
[Pathway Interaction Database:tcr_pathway]
[PUBMED:11376344]
[PUBMED:9094314]
[PUBMED:8083187]
[PUBMED:11994416]
[PUBMED:16365455]
[PUBMED:10072079]
[PUBMED:12361955]
[PUBMED:12755691]
[PUBMED:8642247]
[PUBMED:15125833]
[PUBMED:7509360]
[PUBMED:11353765]
[PUBMED:12941616]
[PUBMED:8700169]
[PUBMED:11120819]
[PUBMED:15899849]
[PUBMED:8990121]
[PUBMED:8702662]
[PUBMED:8164687]
[PUBMED:2141684]
[PUBMED:11567141]
[PUBMED:9846481]
[PUBMED:9489702]
[PUBMED:10811803]
[PUBMED:11368773]
[PUBMED:14557276]
[PUBMED:2548204]
[PUBMED:10318843]
[PUBMED:15536066]
[PUBMED:10652356]
[PUBMED:7568038]
[PUBMED:11175263]
[PUBMED:9438848]
[PUBMED:9692882]
[PUBMED:10209031]
[PUBMED:7509083]
[PUBMED:12874226]
[PUBMED:8673706]
[PUBMED:16733527]
[PUBMED:9822663]
[PUBMED:12738795]
[PUBMED:11904433]
[PUBMED:8084588]
[PUBMED:8114715]
[PUBMED:9312162]
[PUBMED:8790380]
[PUBMED:9677202]
[PUBMED:15802604]
[PUBMED:14702343]
[PUBMED:10903746]
[PUBMED:10807788]
[PUBMED:8176201]
[PUBMED:9207119]
[PUBMED:10790433]
[PUBMED:8892604]
[PUBMED:9665884]
[PUBMED:1639064]
[PUBMED:12421919]
[PUBMED:8246987]
[PUBMED:9710204]
[PUBMED:8146197]
[PUBMED:2190221]
[PUBMED:10229072]
[PUBMED:10021361]
[PUBMED:9924026]
[PUBMED:12186560]
[PUBMED:16649996]
[PUBMED:11287959]
[PUBMED:12917261]
[PUBMED:7545666]
[PUBMED:11250890]
[PUBMED:12842872]
[PUBMED:15879121]
[PUBMED:11567140]
[PUBMED:10209041]
[PUBMED:10556826]
[PUBMED:8183372]
[PUBMED:12397360]
[PUBMED:10506192]
[PUBMED:10861059]
[PUBMED:12507424]
[PUBMED:12845325]
[PUBMED:10745081]
[PUBMED:8195151]
[PUBMED:12024036]
[PUBMED:7524075]
[PUBMED:1464315]
[PUBMED:12138205]
[PUBMED:7544353]
[PUBMED:16906149]
[PUBMED:9637919]
[PUBMED:2470098]
[PUBMED:3919143]
[PUBMED:16005298]
[PUBMED:10918068]
[PUBMED:8636141]
[PUBMED:16921383]
[PUBMED:8479536]
[PUBMED:7556092]
[PUBMED:16582901]
[PUBMED:8805223]
[PUBMED:15933714]
[PUBMED:10224278]
[PUBMED:9819387]
[PUBMED:12881521]
[PUBMED:14988727]
[PUBMED:16849481]
[PUBMED:11390650]
TCR signaling in naive CD8+ T cells
[NCBI:138055]
[Pathway Interaction Database:cd8tcrpathway]
[PUBMED:9094314]
[PUBMED:15125833]
[PUBMED:11994416]
[PUBMED:7509360]
[PUBMED:12755691]
[PUBMED:8642247]
[PUBMED:12361955]
[PUBMED:11956228]
[PUBMED:10072079]
[PUBMED:8977171]
[PUBMED:2141684]
[PUBMED:8700169]
[PUBMED:8164687]
[PUBMED:9489702]
[PUBMED:8702662]
[PUBMED:2548204]
[PUBMED:11175263]
[PUBMED:8114715]
[PUBMED:10209031]
[PUBMED:15536066]
[PUBMED:7678351]
[PUBMED:8673703]
[PUBMED:7830771]
[PUBMED:7509083]
[PUBMED:16733527]
[PUBMED:9438848]
[PUBMED:8790380]
[PUBMED:1639064]
[PUBMED:15980863]
[PUBMED:8084588]
[PUBMED:14702343]
[PUBMED:10790433]
[PUBMED:10807788]
[PUBMED:16169499]
[PUBMED:15802604]
[PUBMED:8892604]
[PUBMED:2114552]
[PUBMED:12421919]
[PUBMED:12917261]
[PUBMED:8146197]
[PUBMED:1335364]
[PUBMED:10021361]
[PUBMED:8183372]
[PUBMED:8627172]
[PUBMED:8898939]
[PUBMED:2190221]
[PUBMED:9710204]
[PUBMED:11287959]
[PUBMED:14764585]
[PUBMED:12954628]
[PUBMED:10209041]
[PUBMED:1464315]
[PUBMED:12507424]
[PUBMED:12732656]
[PUBMED:8195151]
[PUBMED:12138205]
[PUBMED:16005298]
[PUBMED:9312149]
[PUBMED:7544353]
[PUBMED:16906149]
[PUBMED:9637919]
[PUBMED:12845325]
[PUBMED:2470098]
[PUBMED:10918068]
[PUBMED:16116204]
[PUBMED:16921383]
[PUBMED:10562325]
[PUBMED:9819387]
[PUBMED:16582901]
[PUBMED:8034711]
[PUBMED:8479536]
[PUBMED:10640739]
[PUBMED:3919143]
[PUBMED:10224278]
[PUBMED:10811865]
TGF-beta receptor signaling
[NCBI:138024]
[Pathway Interaction Database:tgfbrpathway]
[PUBMED:12118366]
[PUBMED:8242743]
[PUBMED:15221015]
[PUBMED:9335507]
[PUBMED:11278302]
[PUBMED:16601693]
[PUBMED:8391934]
[PUBMED:1333888]
[PUBMED:11438668]
[PUBMED:17327236]
[PUBMED:2879635]
[PUBMED:11483955]
[PUBMED:12717440]
[PUBMED:8047140]
[PUBMED:8576253]
[PUBMED:9865696]
[PUBMED:9346908]
[PUBMED:17197390]
[PUBMED:8533096]
[PUBMED:8756725]
[PUBMED:10615055]
[PUBMED:10934479]
[PUBMED:16251192]
[PUBMED:7706248]
[PUBMED:15946939]
[PUBMED:7774578]
[PUBMED:7988555]
[PUBMED:11278251]
[PUBMED:11027280]
[PUBMED:17420258]
[PUBMED:9169454]
[PUBMED:12151385]
[PUBMED:10757800]
[PUBMED:12543979]
[PUBMED:12475967]
[PUBMED:9679059]
[PUBMED:17673906]
[PUBMED:9774674]
[PUBMED:8893010]
[PUBMED:1544886]
[PUBMED:12958365]
[PUBMED:12110587]
[PUBMED:9233797]
[PUBMED:11163210]
[PUBMED:15496141]
[PUBMED:7693660]
[PUBMED:14657019]
[PUBMED:12429842]
[PUBMED:11124802]
[PUBMED:11389444]
[PUBMED:8798398]
[PUBMED:15356634]
[PUBMED:17272273]
[PUBMED:1657407]
[PUBMED:12589052]
[PUBMED:11016919]
[PUBMED:14718519]
[PUBMED:10777621]
[PUBMED:17384642]
[PUBMED:1310899]
[PUBMED:9856985]
[PUBMED:10519551]
[PUBMED:9155023]
[PUBMED:12134160]
[PUBMED:9215638]
[PUBMED:12134149]
[PUBMED:16157589]
[PUBMED:12356868]
[PUBMED:11387212]
[PUBMED:12034739]
[PUBMED:11739411]
[PUBMED:15761148]
[PUBMED:9463378]
[PUBMED:11583628]
[PUBMED:15684397]
[PUBMED:8947046]
[PUBMED:11781097]
Thyroid hormone signaling pathway
[NCBI:946598]
[KEGG:hsa04919]
[PUBMED:20005976]
[PUBMED:17983645]
[PUBMED:15345678]
[PUBMED:16951130]
[PUBMED:16214361]
[PUBMED:18329679]
[PUBMED:20051527]
[PUBMED:17574003]
[PUBMED:19716314]
[PUBMED:19755667]
[PUBMED:20868274]
[PUBMED:21835053]
[PUBMED:16051672]
[PUBMED:19295177]
[PUBMED:23021374]
[PUBMED:22484490]
Toxoplasmosis
[NCBI:169642]
[KEGG:hsa05145]
[PUBMED:18617274]
[PUBMED:19400868]
[PUBMED:17024357]
[PUBMED:19744886]
[PUBMED:19891610]
[PUBMED:17110955]
[PUBMED:12106793]
[PUBMED:12580944]
[PUBMED:12857995]
[PUBMED:10234174]
[PUBMED:18327664]
[PUBMED:10525166]
[PUBMED:18059289]
[PUBMED:18775432]
[PUBMED:14642303]
[PUBMED:15361242]
[PUBMED:16339966]
[PUBMED:14987366]
[PUBMED:15639739]
Transcriptional Regulation by TP53
[NCBI:1269654]
[REACTOME:R-HSA-3700989]
[PUBMED:26122615]
[PUBMED:19410540]
Transmission across Chemical Synapses
[NCBI:1268766]
[REACTOME:R-HSA-112315]
Trk receptor signaling mediated by PI3K and PLC-gamma
[NCBI:137967]
[Pathway Interaction Database:pi3kplctrkpathway]
[PUBMED:11136977]
[PUBMED:11864996]
[PUBMED:8663990]
[PUBMED:12367511]
[PUBMED:9094314]
[PUBMED:10330161]
[PUBMED:11953455]
[PUBMED:7886457]
[PUBMED:16319926]
[PUBMED:10102273]
[PUBMED:11418861]
[PUBMED:10729337]
[PUBMED:9346240]
[PUBMED:10677043]
[PUBMED:15702476]
[PUBMED:15207235]
[PUBMED:9637919]
VEGFA-VEGFR2 Pathway
[NCBI:1269483]
[REACTOME:R-HSA-4420097]
[PUBMED:17344076]
[PUBMED:16633338]
[PUBMED:19230644]
[PUBMED:13678960]
VEGFR1 specific signals
[NCBI:137924]
[Pathway Interaction Database:vegfr1_pathway]
[PUBMED:9299537]
[PUBMED:9751730]
[PUBMED:9722576]
[PUBMED:14633857]
[PUBMED:11978735]
[PUBMED:11278319]
[PUBMED:12649282]
[PUBMED:16839566]
[PUBMED:12598525]
[PUBMED:12171920]
[PUBMED:12796773]
[PUBMED:16633338]
[PUBMED:11312102]
[PUBMED:9295307]
[PUBMED:10908731]
[PUBMED:16787925]
[PUBMED:11704645]
[PUBMED:9790910]
[PUBMED:10376602]
[PUBMED:9804796]
[PUBMED:11986311]
[PUBMED:10749680]
[PUBMED:12214271]
[PUBMED:9398617]
[PUBMED:8621427]
[PUBMED:11425855]
[PUBMED:15001553]
[PUBMED:10376603]
[PUBMED:7824266]
[PUBMED:10842181]
[PUBMED:9600074]
VEGFR2 mediated cell proliferation
[NCBI:1269485]
[REACTOME:R-HSA-5218921]
[PUBMED:22866201]
[PUBMED:22180219]
[PUBMED:22762016]
VEGFR2 mediated vascular permeability
[NCBI:1269484]
[REACTOME:R-HSA-5218920]
[PUBMED:17008595]
mTOR signaling pathway
[NCBI:83059]
[KEGG:hsa04150]
[NCBI:138001]
[Pathway Interaction Database:mtor_4pathway]
[PUBMED:17277771]
[PUBMED:15341740]
[PUBMED:12172553]
[PUBMED:15718470]
[PUBMED:14651849]
[PUBMED:15268862]
[PUBMED:15306821]
[PUBMED:26046644]
[PUBMED:12869586]
[PUBMED:24556838]
[PUBMED:17928295]
[PUBMED:9427642]
[PUBMED:18046414]
[PUBMED:12912918]
[PUBMED:16286006]
[PUBMED:26658722]
[PUBMED:24842496]
[PUBMED:23465396]
[PUBMED:17709744]
[PUBMED:17599906]
[PUBMED:16919458]
[PUBMED:10364159]
[PUBMED:15342917]
[PUBMED:11500364]
[PUBMED:19812304]
[PUBMED:12482958]
[PUBMED:11729323]
[PUBMED:16962653]
[PUBMED:18952604]
[PUBMED:9465032]
[PUBMED:1496022]
[PUBMED:10567431]
[PUBMED:19114562]
[PUBMED:17510057]
[PUBMED:18604198]
[PUBMED:15545625]
[PUBMED:11914378]
[PUBMED:17461779]
[PUBMED:9445476]
[PUBMED:18497260]
[PUBMED:12604610]
[PUBMED:15071500]
[PUBMED:18925875]
[PUBMED:12906785]
[PUBMED:11287630]
[PUBMED:15004009]
[PUBMED:16756488]
[PUBMED:17043309]
[PUBMED:18198340]
[PUBMED:12820960]
[PUBMED:12747827]
[PUBMED:17053147]
[PUBMED:15851026]
[PUBMED:15467718]
[PUBMED:18762023]
[PUBMED:25242279]
[PUBMED:24698685]
[PUBMED:11175345]
[PUBMED:27304501]
[PUBMED:18411301]
[PUBMED:11500365]
[PUBMED:17693255]
[PUBMED:23694989]
[PUBMED:12231510]
[PUBMED:19446321]
[PUBMED:11418588]
[PUBMED:19258318]
[PUBMED:18439900]
[PUBMED:19225151]
[PUBMED:26185979]
[PUBMED:10357815]
[PUBMED:26269525]
[PUBMED:23421405]
[PUBMED:9271440]
[PUBMED:16915281]
[PUBMED:17141160]
[PUBMED:15249583]
[PUBMED:12912989]
[PUBMED:27027448]
[PUBMED:18423201]
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