full name
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase

synonyms
CDG1K, hMat-1, HMAT1, HMT-1, HMT1, Mat-1, MT-1, ALG1, ENSG00000033011

HGNC
HGNC:18294

Entrez Gene
Gene:56052

ENSEMBL
ENSG00000033011

location
chr: 16
start: 5121810
stop: 5137380
strand: +

OMIM
OMIM:605907: ALG1 (Autosomal recessive inheritance)
OMIM:608540: Congenital disorder of glycosylation, type Ik

transcripts
NM_019109.4

pathways
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:16807922] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein [NCBI:1268715] [REACTOME:R-HSA-446193] [PUBMED:20301507]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
N-Glycan biosynthesis [NCBI:82975] [KEGG:hsa00510] [PUBMED:12684507] [PUBMED:16878994] [PUBMED:11278778] [PUBMED:9111134] [PUBMED:12200473] [PUBMED:15987956]
N-glycan precursor biosynthesis [NCBI:413361] [KEGG:hsa_M00055]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
dolichyl-diphosphooligosaccharide biosynthesis [NCBI:142200] [BIOCYC:HUMAN_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS]