full name
4-aminobutyrate aminotransferase

synonyms
GABA-AT, GABAT, NPD009, ABAT, ENSG00000183044

HGNC
HGNC:23

Entrez Gene
Gene:18

ENSEMBL
ENSG00000183044

location
chr: 16
start: 8768444
stop: 8878432
strand: +

OMIM
OMIM:137150: ABAT (Autosomal recessive inheritance)
OMIM:613163: GABA-transaminase deficiency

transcripts
NM_020686.5
NM_000663.4
NM_001127448.1

pathways
4-aminobutyrate degradation [NCBI:545335] [BIOCYC:HUMAN_PWY-6535] [PUBMED:15528998] [PUBMED:8156960] [PUBMED:15003233] [PUBMED:12208142] [PUBMED:15571623] [PUBMED:13044808]
Alanine, aspartate and glutamate metabolism [NCBI:101142] [KEGG:hsa00250] [PUBMED:9687539]
Butanoate metabolism [NCBI:83007] [KEGG:hsa00650]
Degradation of GABA [NCBI:1268777] [REACTOME:R-HSA-916853] [PUBMED:19172412]
GABA (gamma-Aminobutyrate) shunt [NCBI:413433] [KEGG:hsa_M00027]
GABA shunt [NCBI:142350] [BIOCYC:HUMAN_GLUDEG-I-PWY] [PUBMED:9816471] [PUBMED:15571623] [PUBMED:15528998] [PUBMED:12208142] [PUBMED:13044808] [PUBMED:15003233] [PUBMED:8156960] [PUBMED:8207021]
GABA synthesis, release, reuptake and degradation [NCBI:1268774] [REACTOME:R-HSA-888590] [PUBMED:19428801] [PUBMED:16787421]
GABAergic synapse [NCBI:377263] [KEGG:hsa04727] [PUBMED:21555068] [PUBMED:20655485] [PUBMED:16932937] [PUBMED:17499108] [PUBMED:12086709] [PUBMED:20655481] [PUBMED:21376567] [PUBMED:19374920] [PUBMED:17499109] [PUBMED:10780899] [PUBMED:16787421] [PUBMED:15210304] [PUBMED:18382465] [PUBMED:12888801] [PUBMED:9364667]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotransmitter Release Cycle [NCBI:1268768] [REACTOME:R-HSA-112310] [PUBMED:15217342] [PUBMED:16819626] [PUBMED:17880890] [PUBMED:16865347]
Propanoate metabolism [NCBI:83004] [KEGG:hsa00640]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]
Valine, leucine and isoleucine degradation [NCBI:82952] [KEGG:hsa00280]
beta-Alanine metabolism [NCBI:82966] [KEGG:hsa00410]
beta-alanine degradation [NCBI:142334] [BIOCYC:HUMAN_BETA-ALA-DEGRADATION-I-PWY] [PUBMED:10447691] [PUBMED:5762452] [PUBMED:1527093] [PUBMED:11238307] [PUBMED:8356911] [PUBMED:2768248]
valine degradation [NCBI:142387] [BIOCYC:HUMAN_VALDEG-PWY] [PUBMED:10745006] [PUBMED:3827880] [PUBMED:6933702]