Logo
full name
PYD and CARD domain containing

synonyms
ASC, CARD5, TMS, TMS-1, TMS1, PYCARD, ENSG00000103490

HGNC
HGNC:16608

Entrez Gene
Gene:29108

ENSEMBL
ENSG00000103490

location
chr: 16
start: 31212807
stop: 31214097
strand: -

transcripts
NM_145182.2
NM_013258.4

pathways
C-type lectin receptors (CLRs) [NCBI:1269303] [REACTOME:R-HSA-5621481] [PUBMED:19521399] [PUBMED:24330199]
CLEC7A (Dectin-1) signaling [NCBI:1269304] [REACTOME:R-HSA-5607764] [PUBMED:12719478] [PUBMED:19223162]
CLEC7A/inflammasome pathway [NCBI:1269307] [REACTOME:R-HSA-5660668] [PUBMED:22267217] [PUBMED:21531876]
Cytosolic DNA-sensing pathway [NCBI:125137] [KEGG:hsa04623] [PUBMED:18573338] [PUBMED:19665965] [PUBMED:19567913] [PUBMED:18280611] [PUBMED:18724932] [PUBMED:19497760] [PUBMED:16286919] [PUBMED:19122387] [PUBMED:19590578] [PUBMED:23258413] [PUBMED:18375758] [PUBMED:19321146] [PUBMED:19362700] [PUBMED:18941233] [PUBMED:19767723]
Direct p53 effectors [NCBI:137939] [Pathway Interaction Database:p53downstreampathway] [PUBMED:7479001] [PUBMED:19626115] [PUBMED:10692390] [PUBMED:15289308] [PUBMED:14688482] [PUBMED:16301995] [PUBMED:11850816] [PUBMED:12370809] [PUBMED:16260627] [PUBMED:15186775] [PUBMED:15580302] [PUBMED:10748162] [PUBMED:10919640] [PUBMED:19011621] [PUBMED:12438652] [PUBMED:11559530] [PUBMED:11641774] [PUBMED:11971958] [PUBMED:9659898] [PUBMED:9343394] [PUBMED:10716435] [PUBMED:17146433] [PUBMED:17719542] [PUBMED:17938176] [PUBMED:17409421] [PUBMED:11032029] [PUBMED:15781865] [PUBMED:11463392] [PUBMED:9736732] [PUBMED:17268548] [PUBMED:8570655] [PUBMED:18046411] [PUBMED:12944906] [PUBMED:16249378] [PUBMED:15273740] [PUBMED:15598651] [PUBMED:10618379] [PUBMED:15958553] [PUBMED:17189187] [PUBMED:17145718] [PUBMED:11988847] [PUBMED:8119988] [PUBMED:12089322] [PUBMED:16286009] [PUBMED:12890671] [PUBMED:12402042] [PUBMED:10618714] [PUBMED:14730312] [PUBMED:12857899] [PUBMED:14963330] [PUBMED:11278953] [PUBMED:11973653] [PUBMED:12692263] [PUBMED:10984493] [PUBMED:10640990] [PUBMED:11545734] [PUBMED:16151013] [PUBMED:12372430] [PUBMED:16651407] [PUBMED:9891062] [PUBMED:12606722] [PUBMED:12453409] [PUBMED:15377670] [PUBMED:12667443] [PUBMED:17707234] [PUBMED:9920903] [PUBMED:14992722] [PUBMED:15790310] [PUBMED:15831478] [PUBMED:11314010] [PUBMED:10329733] [PUBMED:17264218] [PUBMED:11511362] [PUBMED:11919562] [PUBMED:11814693] [PUBMED:17554199] [PUBMED:18250150] [PUBMED:10518217] [PUBMED:10891498] [PUBMED:10973264] [PUBMED:15077116] [PUBMED:16230375] [PUBMED:18485870] [PUBMED:7796420] [PUBMED:15710382] [PUBMED:17409411] [PUBMED:8319905] [PUBMED:10684646] [PUBMED:7566179] [PUBMED:8887630] [PUBMED:11807984] [PUBMED:9841917] [PUBMED:12654245] [PUBMED:9023107] [PUBMED:15103385] [PUBMED:11684014] [PUBMED:17110336] [PUBMED:11278253] [PUBMED:14576823] [PUBMED:8418500] [PUBMED:11350971] [PUBMED:11840333] [PUBMED:7651818] [PUBMED:7651386] [PUBMED:15378026] [PUBMED:15607964] [PUBMED:11279192] [PUBMED:10777218] [PUBMED:15334053] [PUBMED:12138177] [PUBMED:9619826] [PUBMED:16278683] [PUBMED:17189186] [PUBMED:16140933] [PUBMED:10094469] [PUBMED:9926927] [PUBMED:17719541] [PUBMED:15735003] [PUBMED:12853982] [PUBMED:14707288] [PUBMED:10777207]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Inflammasomes [NCBI:1269253] [REACTOME:R-HSA-622312] [PUBMED:20303873] [PUBMED:19120479]
Influenza A [NCBI:217173] [KEGG:hsa05164] [PUBMED:17267598] [PUBMED:18049471] [PUBMED:16882036] [PUBMED:11907320] [PUBMED:17944269] [PUBMED:20629046] [PUBMED:17072332] [PUBMED:18588994] [PUBMED:19864182] [PUBMED:19290913] [PUBMED:19420020] [PUBMED:17213831] [PUBMED:9060654] [PUBMED:19481124] [PUBMED:16494716] [PUBMED:21147034] [PUBMED:18980544] [PUBMED:20020828] [PUBMED:15502848] [PUBMED:19782761]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Legionellosis [NCBI:469200] [KEGG:hsa05134] [PUBMED:19021631] [PUBMED:19157961] [PUBMED:20375353] [PUBMED:19478083] [PUBMED:18284575] [PUBMED:19386084] [PUBMED:19666608] [PUBMED:15972519] [PUBMED:18549456] [PUBMED:1721820] [PUBMED:17124169] [PUBMED:19687203] [PUBMED:18363881] [PUBMED:19343209] [PUBMED:20941588] [PUBMED:16824952] [PUBMED:18281405] [PUBMED:18048909] [PUBMED:16495539] [PUBMED:12427954]
NOD-like receptor signaling pathway [NCBI:122191] [KEGG:hsa04621] [PUBMED:25330206] [PUBMED:21575908] [PUBMED:23846113] [PUBMED:26549800] [PUBMED:16493424] [PUBMED:23124073] [PUBMED:24840700] [PUBMED:27291964] [PUBMED:27012466] [PUBMED:24707857] [PUBMED:19767725] [PUBMED:25879280] [PUBMED:23215645] [PUBMED:22819539] [PUBMED:23702978] [PUBMED:20643110] [PUBMED:25879288] [PUBMED:26655628] [PUBMED:25145756] [PUBMED:24718315] [PUBMED:26482951] [PUBMED:25526305] [PUBMED:26121197] [PUBMED:22430786]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways [NCBI:1269251] [REACTOME:R-HSA-168643] [PUBMED:18928408]
Pertussis [NCBI:218111] [KEGG:hsa05133] [PUBMED:20610650] [PUBMED:12701623] [PUBMED:15201703] [PUBMED:18401006] [PUBMED:20210554] [PUBMED:16622221] [PUBMED:17148436] [PUBMED:21204863] [PUBMED:20404851] [PUBMED:10540218] [PUBMED:16999837] [PUBMED:16481212] [PUBMED:16863919] [PUBMED:16390441] [PUBMED:21423776] [PUBMED:17328678] [PUBMED:12915094]
Salmonella infection [NCBI:375172] [KEGG:hsa05132] [PUBMED:18407067] [PUBMED:18411289] [PUBMED:18778407] [PUBMED:20123714] [PUBMED:20158475] [PUBMED:19779561] [PUBMED:18026123] [PUBMED:19930040] [PUBMED:12675800] [PUBMED:11755407] [PUBMED:11489966] [PUBMED:19775254] [PUBMED:20943123] [PUBMED:17690885] [PUBMED:16938850] [PUBMED:20526845] [PUBMED:11567004] [PUBMED:17074883] [PUBMED:11825778] [PUBMED:17071592] [PUBMED:16800847] [PUBMED:16611232] [PUBMED:10499590]
The AIM2 inflammasome [NCBI:1269257] [REACTOME:R-HSA-844615] [PUBMED:20303873]
The NLRP3 inflammasome [NCBI:1269254] [REACTOME:R-HSA-844456] [PUBMED:19501527] [PUBMED:20303873]