full name
integrin subunit alpha M

synonyms
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, ITGAM, ENSG00000169896

HGNC
HGNC:6149

Entrez Gene
Gene:3684

ENSEMBL
ENSG00000169896

location
chr: 16
start: 31271288
stop: 31344213
strand: +

transcripts
NM_001145808.1
NM_000632.3

pathways
Amoebiasis [NCBI:167324] [KEGG:hsa05146] [PUBMED:9832261] [PUBMED:16380324] [PUBMED:14700586] [PUBMED:18725798] [PUBMED:12142490] [PUBMED:10637584] [PUBMED:20145703] [PUBMED:11378035] [PUBMED:12160867] [PUBMED:15813717] [PUBMED:19207103] [PUBMED:12660071] [PUBMED:20303955] [PUBMED:11352795] [PUBMED:14502002] [PUBMED:10756002] [PUBMED:17702556] [PUBMED:17576362]
Cell adhesion molecules (CAMs) [NCBI:83069] [KEGG:hsa04514] [PUBMED:15923648] [PUBMED:12500939] [PUBMED:15056568] [PUBMED:14519386] [PUBMED:12234363] [PUBMED:10964748] [PUBMED:15071551] [PUBMED:15551862] [PUBMED:14690046] [PUBMED:9150551] [PUBMED:14519398] [PUBMED:14556710] [PUBMED:11860281] [PUBMED:10664064] [PUBMED:9597126] [PUBMED:11050419] [PUBMED:12367625] [PUBMED:10798271] [PUBMED:16034094] [PUBMED:15115723] [PUBMED:15728677] [PUBMED:11910893] [PUBMED:15561584] [PUBMED:15882774] [PUBMED:12810109]
Cell surface interactions at the vascular wall [NCBI:1269373] [REACTOME:R-HSA-202733] [PUBMED:17525755] [PUBMED:11282294] [PUBMED:10798271] [PUBMED:8578462] [PUBMED:14615387] [PUBMED:16115029]
Complement and coagulation cascades [NCBI:83073] [KEGG:hsa04610] [PUBMED:23564577] [PUBMED:25309880] [PUBMED:26082779] [PUBMED:23110467] [PUBMED:20027185] [PUBMED:25568220] [PUBMED:26324800] [PUBMED:25705421] [PUBMED:21811895] [PUBMED:23911436] [PUBMED:23564578] [PUBMED:24924409] [PUBMED:26489954] [PUBMED:17635716]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Extracellular matrix organization [NCBI:1270244] [REACTOME:R-HSA-1474244] [PUBMED:21123617] [PUBMED:21917992] [PUBMED:12845610]
Hematopoietic cell lineage [NCBI:83078] [KEGG:hsa04640] [PUBMED:15629410] [PUBMED:15738953] [PUBMED:11905810] [PUBMED:15156179] [PUBMED:12415312] [PUBMED:14985712] [PUBMED:9927518] [PUBMED:15771582] [PUBMED:14670296] [PUBMED:12360214]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Integrin cell surface interactions [NCBI:1270260] [REACTOME:R-HSA-216083] [PUBMED:10215583] [PUBMED:15147720] [PUBMED:12231361] [PUBMED:8866399] [PUBMED:19273203]
Interleukin-4 and 13 signaling [NCBI:1470923] [REACTOME:R-HSA-6785807] [PUBMED:12704343] [PUBMED:10358772]
Legionellosis [NCBI:469200] [KEGG:hsa05134] [PUBMED:19021631] [PUBMED:19157961] [PUBMED:20375353] [PUBMED:19478083] [PUBMED:18284575] [PUBMED:19386084] [PUBMED:19666608] [PUBMED:15972519] [PUBMED:18549456] [PUBMED:1721820] [PUBMED:17124169] [PUBMED:19687203] [PUBMED:18363881] [PUBMED:19343209] [PUBMED:20941588] [PUBMED:16824952] [PUBMED:18281405] [PUBMED:18048909] [PUBMED:16495539] [PUBMED:12427954]
Leishmaniasis [NCBI:144181] [KEGG:hsa05140] [PUBMED:11890722] [PUBMED:7916951] [PUBMED:10417174] [PUBMED:11298294] [PUBMED:10586030] [PUBMED:15322192] [PUBMED:15831826] [PUBMED:11728310] [PUBMED:15039466] [PUBMED:10462516] [PUBMED:10608501] [PUBMED:15721837] [PUBMED:15639739] [PUBMED:14762510] [PUBMED:18793215] [PUBMED:7591091] [PUBMED:12438359] [PUBMED:18070909] [PUBMED:17543969] [PUBMED:15983048] [PUBMED:16848789] [PUBMED:10770277] [PUBMED:9504340]
Leukocyte transendothelial migration [NCBI:83083] [KEGG:hsa04670] [PUBMED:15629883] [PUBMED:10975856] [PUBMED:14976004] [PUBMED:15265790] [PUBMED:15173832] [PUBMED:12540948] [PUBMED:15771581] [PUBMED:15604886] [PUBMED:14977592]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Pertussis [NCBI:218111] [KEGG:hsa05133] [PUBMED:20610650] [PUBMED:12701623] [PUBMED:15201703] [PUBMED:18401006] [PUBMED:20210554] [PUBMED:16622221] [PUBMED:17148436] [PUBMED:21204863] [PUBMED:20404851] [PUBMED:10540218] [PUBMED:16999837] [PUBMED:16481212] [PUBMED:16863919] [PUBMED:16390441] [PUBMED:21423776] [PUBMED:17328678] [PUBMED:12915094]
Phagosome [NCBI:153910] [KEGG:hsa04145] [PUBMED:17637737] [PUBMED:18513324] [PUBMED:15894272] [PUBMED:10684585] [PUBMED:18492791] [PUBMED:15036145] [PUBMED:17245426]
Rap1 signaling pathway [NCBI:868086] [KEGG:hsa04015] [PUBMED:17624944] [PUBMED:12351703] [PUBMED:10579920] [PUBMED:19159611] [PUBMED:18363565] [PUBMED:12765839] [PUBMED:12508104] [PUBMED:11331911] [PUBMED:17182900] [PUBMED:15803158] [PUBMED:19615876] [PUBMED:21402149] [PUBMED:17624948] [PUBMED:17383543] [PUBMED:14607972] [PUBMED:15780587] [PUBMED:19710505]
Regulation of actin cytoskeleton [NCBI:83089] [KEGG:hsa04810] [PUBMED:11152757] [PUBMED:11082272] [PUBMED:10574699] [PUBMED:11082269] [PUBMED:14657486] [PUBMED:14744429] [PUBMED:12700767]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Staphylococcus aureus infection [NCBI:172846] [KEGG:hsa05150] [PUBMED:18837785] [PUBMED:16679003] [PUBMED:18544012] [PUBMED:15372083] [PUBMED:19112495] [PUBMED:16640587] [PUBMED:15561843] [PUBMED:16322743] [PUBMED:16710608] [PUBMED:16111912] [PUBMED:11361034] [PUBMED:12091905] [PUBMED:16724100] [PUBMED:16242332] [PUBMED:17132726] [PUBMED:20178484] [PUBMED:16086019] [PUBMED:12228315] [PUBMED:19503103] [PUBMED:14993252] [PUBMED:18061675] [PUBMED:17114475] [PUBMED:17848512] [PUBMED:17517597] [PUBMED:20133685] [PUBMED:18045383] [PUBMED:16184199] [PUBMED:17893203] [PUBMED:20062962] [PUBMED:15273292]
Toll Like Receptor 4 (TLR4) Cascade [NCBI:1269234] [REACTOME:R-HSA-166016]
Toll-Like Receptors Cascades [NCBI:1269204] [REACTOME:R-HSA-168898] [PUBMED:15950447] [PUBMED:12893815] [PUBMED:15976490] [PUBMED:15585605] [PUBMED:14751757]
Transcriptional misregulation in cancer [NCBI:523016] [KEGG:hsa05202] [PUBMED:17327229] [PUBMED:20190806] [PUBMED:20145147] [PUBMED:11313274] [PUBMED:11863357] [PUBMED:19472090] [PUBMED:18330902] [PUBMED:19738075] [PUBMED:15024077] [PUBMED:12032780] [PUBMED:14630078] [PUBMED:21765642] [PUBMED:19564705] [PUBMED:17101797] [PUBMED:15160934] [PUBMED:15688424] [PUBMED:15985538] [PUBMED:12527902] [PUBMED:12511414] [PUBMED:11607818] [PUBMED:17222504] [PUBMED:15826838] [PUBMED:21747944] [PUBMED:19406209] [PUBMED:10350329] [PUBMED:21779514] [PUBMED:18563191] [PUBMED:16946003] [PUBMED:17250957] [PUBMED:12670461] [PUBMED:12529654] [PUBMED:18855877] [PUBMED:17505060] [PUBMED:20153925] [PUBMED:20490326] [PUBMED:12130514] [PUBMED:18648544] [PUBMED:19855079] [PUBMED:10717473] [PUBMED:20478527] [PUBMED:11340171] [PUBMED:16169901] [PUBMED:14998494] [PUBMED:19233641] [PUBMED:19133982] [PUBMED:12393465] [PUBMED:19059936] [PUBMED:18172298] [PUBMED:10500199] [PUBMED:19141473] [PUBMED:10537274] [PUBMED:15156184] [PUBMED:14701735] [PUBMED:19422821] [PUBMED:21518926] [PUBMED:18850010] [PUBMED:19075677] [PUBMED:18457914] [PUBMED:12527906] [PUBMED:15644444] [PUBMED:10784387] [PUBMED:17024155] [PUBMED:19075268] [PUBMED:15826834] [PUBMED:21849159] [PUBMED:21123453] [PUBMED:20974671] [PUBMED:20863376]
Tuberculosis [NCBI:213780] [KEGG:hsa05152] [PUBMED:20199890] [PUBMED:21274449] [PUBMED:17359235] [PUBMED:20415982] [PUBMED:18541216] [PUBMED:19369951] [PUBMED:15083155] [PUBMED:11378475] [PUBMED:15228522] [PUBMED:19634703] [PUBMED:21274433] [PUBMED:19563525] [PUBMED:18407066] [PUBMED:18288961] [PUBMED:16200082] [PUBMED:17785780] [PUBMED:11932234]
amb2 Integrin signaling [NCBI:137945] [Pathway Interaction Database:amb2_neutrophils_pathway] [PUBMED:15004192] [PUBMED:16260637] [PUBMED:8874219] [PUBMED:12736251] [PUBMED:12824186] [PUBMED:17202407] [PUBMED:15458976] [PUBMED:12208882] [PUBMED:10985384] [PUBMED:8598477] [PUBMED:8157977] [PUBMED:14530377] [PUBMED:16567504] [PUBMED:7836767] [PUBMED:17003381] [PUBMED:10899906] [PUBMED:15741160] [PUBMED:9920836] [PUBMED:12941957] [PUBMED:12773513] [PUBMED:15283855] [PUBMED:16854414] [PUBMED:15217824] [PUBMED:15090462] [PUBMED:14769799] [PUBMED:16905120] [PUBMED:9831565] [PUBMED:12194823] [PUBMED:17268551] [PUBMED:17133598] [PUBMED:15153528] [PUBMED:11418469] [PUBMED:14623906] [PUBMED:12036876] [PUBMED:16391519] [PUBMED:15304494] [PUBMED:16093349] [PUBMED:16403785]