Logo
full name
translocated promoter region, nuclear basket protein

synonyms
TPR, ENSG00000047410

HGNC
HGNC:12017

Entrez Gene
Gene:7175

ENSEMBL
ENSG00000047410

location
chr: 1
start: 186280784
stop: 186344883
strand: -

transcripts
NM_003292.2

pathways
Antiviral mechanism by IFN-stimulated genes [NCBI:1269316] [REACTOME:R-HSA-1169410]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cellular response to heat stress [NCBI:1270421] [REACTOME:R-HSA-3371556] [PUBMED:8455624] [PUBMED:8441385]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Export of Viral Ribonucleoproteins from Nucleus [NCBI:1269121] [REACTOME:R-HSA-168274] [PUBMED:11118210] [PUBMED:17081640] [PUBMED:16806605]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Gene Silencing by RNA [NCBI:1269719] [REACTOME:R-HSA-211000] [PUBMED:15741316] [PUBMED:25565029] [PUBMED:19165215] [PUBMED:21755468] [PUBMED:16510870] [PUBMED:19412884] [PUBMED:17560368] [PUBMED:19239886]
Glucose transport [NCBI:1269921] [REACTOME:R-HSA-70153] [PUBMED:11780753]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
HIV Life Cycle [NCBI:1269058] [REACTOME:R-HSA-162587] [PUBMED:9188609] [PUBMED:9759480]
Hexose transport [NCBI:1269920] [REACTOME:R-HSA-189200] [PUBMED:16186415] [PUBMED:15546855]
Host Interactions of HIV factors [NCBI:1269091] [REACTOME:R-HSA-162909]
Host Interactions with Influenza Factors [NCBI:1269130] [REACTOME:R-HSA-168253]
ISG15 antiviral mechanism [NCBI:1269317] [REACTOME:R-HSA-1169408] [PUBMED:20153823] [PUBMED:12582176] [PUBMED:16009940] [PUBMED:20946978] [PUBMED:15970528]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Influenza Infection [NCBI:1269108] [REACTOME:R-HSA-168254]
Influenza Life Cycle [NCBI:1269109] [REACTOME:R-HSA-168255]
Influenza Viral RNA Transcription and Replication [NCBI:1269115] [REACTOME:R-HSA-168273] [PUBMED:2214032] [PUBMED:6863242] [PUBMED:6616622] [PUBMED:6269803]
Interactions of Rev with host cellular proteins [NCBI:1269095] [REACTOME:R-HSA-177243] [PUBMED:9837918]
Interactions of Vpr with host cellular proteins [NCBI:1269092] [REACTOME:R-HSA-176033] [PUBMED:10620603] [PUBMED:10958988] [PUBMED:15817944] [PUBMED:11531413] [PUBMED:8041786] [PUBMED:11815283] [PUBMED:16354571] [PUBMED:8709199] [PUBMED:7474100] [PUBMED:9436978] [PUBMED:7474080] [PUBMED:9582382] [PUBMED:9188632] [PUBMED:10684278]
Interferon Signaling [NCBI:1269311] [REACTOME:R-HSA-913531] [PUBMED:18929502] [PUBMED:15607020] [PUBMED:15864272] [PUBMED:14525967] [PUBMED:19059436]
Late Phase of HIV Life Cycle [NCBI:1269069] [REACTOME:R-HSA-162599] [PUBMED:2825027] [PUBMED:10550206] [PUBMED:10562489] [PUBMED:15719065] [PUBMED:15183343] [PUBMED:3031512] [PUBMED:9891806] [PUBMED:2784194]
M Phase [NCBI:1269810] [REACTOME:R-HSA-68886]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Metabolism of non-coding RNA [NCBI:1269731] [REACTOME:R-HSA-194441]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Mitotic Prophase [NCBI:1269811] [REACTOME:R-HSA-68875]
NEP/NS2 Interacts with the Cellular Export Machinery [NCBI:1269123] [REACTOME:R-HSA-168333] [PUBMED:17081640] [PUBMED:11118210] [PUBMED:12970177]
NS1 Mediated Effects on Host Pathways [NCBI:1269131] [REACTOME:R-HSA-168276]
Nuclear Envelope Breakdown [NCBI:1269815] [REACTOME:R-HSA-2980766] [PUBMED:19234477]
Nuclear Pore Complex (NPC) Disassembly [NCBI:1269817] [REACTOME:R-HSA-3301854] [PUBMED:18316408] [PUBMED:21335236] [PUBMED:12589057] [PUBMED:19234477] [PUBMED:22901806]
Nuclear import of Rev protein [NCBI:1269096] [REACTOME:R-HSA-180746]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Processing of Capped Intron-Containing Pre-mRNA [NCBI:1269688] [REACTOME:R-HSA-72203]
RNA transport [NCBI:177876] [KEGG:hsa03013] [PUBMED:10872469] [PUBMED:17401408] [PUBMED:20733056] [PUBMED:11018020] [PUBMED:15519698] [PUBMED:16314458] [PUBMED:15901496] [PUBMED:9548260] [PUBMED:18313922]
Regulation of Glucokinase by Glucokinase Regulatory Protein [NCBI:1269922] [REACTOME:R-HSA-170822] [PUBMED:14627435] [PUBMED:10601273]
Regulation of HSF1-mediated heat shock response [NCBI:1270425] [REACTOME:R-HSA-3371453] [PUBMED:7623826]
Rev-mediated nuclear export of HIV RNA [NCBI:1269085] [REACTOME:R-HSA-165054] [PUBMED:12932730] [PUBMED:8805303] [PUBMED:9791012]
SLC-mediated transmembrane transport [NCBI:1269907] [REACTOME:R-HSA-425407] [PUBMED:14624363] [PUBMED:19164095]
SUMO E3 ligases SUMOylate target proteins [NCBI:1268743] [REACTOME:R-HSA-3108232] [PUBMED:20674646] [PUBMED:17763827] [PUBMED:19471022] [PUBMED:23746258] [PUBMED:24016193] [PUBMED:23503365] [PUBMED:21252943] [PUBMED:17000644] [PUBMED:24273646] [PUBMED:22811915] [PUBMED:21693764] [PUBMED:23277067] [PUBMED:21102611]
SUMOylation [NCBI:1268738] [REACTOME:R-HSA-2990846] [PUBMED:21102611] [PUBMED:20674646] [PUBMED:23514139] [PUBMED:19923268] [PUBMED:20462400] [PUBMED:17768054]
SUMOylation of DNA damage response and repair proteins [NCBI:1268744] [REACTOME:R-HSA-3108214] [PUBMED:22018829] [PUBMED:24926426] [PUBMED:23122649] [PUBMED:23781231] [PUBMED:23416108] [PUBMED:21486569] [PUBMED:23746258] [PUBMED:21896653] [PUBMED:22357966] [PUBMED:21664912]
SUMOylation of DNA replication proteins [NCBI:1339113] [REACTOME:R-HSA-4615885] [PUBMED:22812528] [PUBMED:17031663] [PUBMED:22918591] [PUBMED:22732495] [PUBMED:16368276]
SUMOylation of RNA binding proteins [NCBI:1339112] [REACTOME:R-HSA-4570464] [PUBMED:23979992] [PUBMED:15161980]
Thyroid cancer [NCBI:83112] [KEGG:hsa05216] [PUBMED:16189702] [PUBMED:17062879] [PUBMED:16557281] [PUBMED:16242838] [PUBMED:12094241] [PUBMED:16551846] [PUBMED:16946003] [PUBMED:11165748]
Transcriptional regulation by small RNAs [NCBI:1269723] [REACTOME:R-HSA-5578749] [PUBMED:19771207] [PUBMED:18852463] [PUBMED:25131816] [PUBMED:22283730] [PUBMED:22445173] [PUBMED:24388755] [PUBMED:15963934] [PUBMED:24468964] [PUBMED:22961379] [PUBMED:22722852] [PUBMED:21948593] [PUBMED:22053081] [PUBMED:15643423] [PUBMED:16373483] [PUBMED:24384674] [PUBMED:23150874] [PUBMED:20373265] [PUBMED:22336708] [PUBMED:16936726] [PUBMED:24680896] [PUBMED:23882114]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
Transport of Mature Transcript to Cytoplasm [NCBI:1269693] [REACTOME:R-HSA-72202]
Transport of Mature mRNA Derived from an Intronless Transcript [NCBI:1269698] [REACTOME:R-HSA-159231]
Transport of Mature mRNA derived from an Intron-Containing Transcript [NCBI:1269694] [REACTOME:R-HSA-159236]
Transport of Mature mRNAs Derived from Intronless Transcripts [NCBI:1269695] [REACTOME:R-HSA-159234]
Transport of Ribonucleoproteins into the Host Nucleus [NCBI:1269114] [REACTOME:R-HSA-168271]
Transport of the SLBP Dependant Mature mRNA [NCBI:1269696] [REACTOME:R-HSA-159230]
Transport of the SLBP independent Mature mRNA [NCBI:1269697] [REACTOME:R-HSA-159227]
Viral Messenger RNA Synthesis [NCBI:1269117] [REACTOME:R-HSA-168325] [PUBMED:16933365] [PUBMED:16806605] [PUBMED:15298169]
Vpr-mediated nuclear import of PICs [NCBI:1269094] [REACTOME:R-HSA-180910]
snRNP Assembly [NCBI:1269732] [REACTOME:R-HSA-191859] [PUBMED:15130578]
tRNA processing [NCBI:1309088] [REACTOME:R-HSA-72306] [PUBMED:24315934] [PUBMED:24917879] [PUBMED:7759547] [PUBMED:24898039] [PUBMED:26016801] [PUBMED:24490730] [PUBMED:20810645] [PUBMED:21910628]
tRNA processing in the nucleus [NCBI:1309089] [REACTOME:R-HSA-6784531] [PUBMED:12045094] [PUBMED:20101632] [PUBMED:20716516] [PUBMED:20810645] [PUBMED:21572561] [PUBMED:16040803] [PUBMED:16061803] [PUBMED:22426497] [PUBMED:25755220] [PUBMED:16364630] [PUBMED:24596576] [PUBMED:15879697] [PUBMED:24898039] [PUBMED:11871657]