full name
melanocortin 1 receptor

synonyms
CMM5, MSH-R, SHEP2, MC1R, ENSG00000258839

HGNC
HGNC:6929

Entrez Gene
Gene:4157

ENSEMBL
ENSG00000258839

location
chr: 16
start: 89984287
stop: 89987385
strand: +

OMIM
OMIM:155555: MC1R
OMIM:613098: [Analgesia from kappa-opioid receptor agonist, female-specific]
OMIM:266300: [Skin/hair/eye pigmentation 2, blond hair/fair skin]
OMIM:266300: [Skin/hair/eye pigmentation 2, red hair/fair skin]
OMIM:203200: {Albinism, oculocutaneous, type II, modifier of}
OMIM:613099: {Melanoma, cutaneous malignant, 5}
OMIM:266300: {UV-induced skin damage}

transcripts
NM_002386.3

pathways
Class A/1 (Rhodopsin-like receptors) [NCBI:1269545] [REACTOME:R-HSA-373076] [PUBMED:16902930]
G alpha (s) signalling events [NCBI:1269575] [REACTOME:R-HSA-418555] [PUBMED:12036966]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Melanogenesis [NCBI:83092] [KEGG:hsa04916] [PUBMED:11041354] [PUBMED:10347209] [PUBMED:15016298] [PUBMED:11023702] [PUBMED:11602344] [PUBMED:12753399] [PUBMED:10841026] [PUBMED:16822996] [PUBMED:15383650] [PUBMED:9263329] [PUBMED:16246839] [PUBMED:10643996] [PUBMED:12894244]
Neuroactive ligand-receptor interaction [NCBI:83053] [KEGG:hsa04080]
Peptide ligand-binding receptors [NCBI:1269546] [REACTOME:R-HSA-375276] [PUBMED:14576899] [PUBMED:10977869] [PUBMED:16918325] [PUBMED:16847439] [PUBMED:17293890] [PUBMED:15734727] [PUBMED:12895595] [PUBMED:17604107] [PUBMED:14507421] [PUBMED:12432945] [PUBMED:16612131]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]