Logo
full name
arrestin beta 2

synonyms
ARB2, ARR2, BARR2, ARRB2, ENSG00000141480

HGNC
HGNC:712

Entrez Gene
Gene:409

ENSEMBL
ENSG00000141480

location
chr: 17
start: 4613789
stop: 4624795
strand: +

transcripts
NM_001257328.1
NM_001257330.1
NM_004313.3
NM_001257329.1
NM_001257331.1
NM_199004.1
NR_047516.1

pathways
ALK1 signaling events [NCBI:137968] [Pathway Interaction Database:alk1pathway] [PUBMED:9748228] [PUBMED:17071858] [PUBMED:14580334] [PUBMED:9920917] [PUBMED:17911401] [PUBMED:17311849] [PUBMED:8140412] [PUBMED:17068149] [PUBMED:8242742] [PUBMED:16571110] [PUBMED:9872992] [PUBMED:8612709] [PUBMED:18065769] [PUBMED:1326540] [PUBMED:15385967] [PUBMED:8756725] [PUBMED:11927558] [PUBMED:10187774] [PUBMED:8294451] [PUBMED:15702480] [PUBMED:10716993] [PUBMED:17540773] [PUBMED:19592636]
ARMS-mediated activation [NCBI:1269471] [REACTOME:R-HSA-170984] [PUBMED:9069267]
Activated NOTCH1 Transmits Signal to the Nucleus [NCBI:1269536] [REACTOME:R-HSA-2122948] [PUBMED:15574878] [PUBMED:19726682] [PUBMED:18628966] [PUBMED:9620803] [PUBMED:12530964] [PUBMED:15652348] [PUBMED:18237417] [PUBMED:10882063] [PUBMED:11006133] [PUBMED:18077452] [PUBMED:9462510] [PUBMED:14567914] [PUBMED:17003037] [PUBMED:19524514] [PUBMED:17028573] [PUBMED:10206645] [PUBMED:20418862] [PUBMED:15965470] [PUBMED:16284625] [PUBMED:11226752] [PUBMED:19567869] [PUBMED:12354787] [PUBMED:11740940] [PUBMED:9590294] [PUBMED:15824097] [PUBMED:9244301] [PUBMED:18043734] [PUBMED:9315665] [PUBMED:10879540] [PUBMED:9819428] [PUBMED:8313469] [PUBMED:18296446]
Activation of SMO [NCBI:1269642] [REACTOME:R-HSA-5635838] [PUBMED:16339192] [PUBMED:21356043] [PUBMED:20395968] [PUBMED:23719536] [PUBMED:24582806] [PUBMED:14636583] [PUBMED:19081070] [PUBMED:17641202] [PUBMED:17762891] [PUBMED:10966113] [PUBMED:17960137] [PUBMED:22981989] [PUBMED:20412775] [PUBMED:24845016] [PUBMED:23079593] [PUBMED:21801010] [PUBMED:21695114] [PUBMED:15691767] [PUBMED:22986504] [PUBMED:16459297] [PUBMED:14614827] [PUBMED:19906846] [PUBMED:12192414] [PUBMED:20844016]
Arf6 signaling events [NCBI:138034] [Pathway Interaction Database:arf6_pathway] [PUBMED:18164504] [PUBMED:15509780] [PUBMED:11481345] [PUBMED:18084281] [PUBMED:15775968] [PUBMED:18094045] [PUBMED:17409355] [PUBMED:11532961] [PUBMED:10480924] [PUBMED:15126638] [PUBMED:17398097] [PUBMED:18026091] [PUBMED:17353194] [PUBMED:15793570] [PUBMED:16650966] [PUBMED:12920129] [PUBMED:11278939] [PUBMED:9742223] [PUBMED:11062263] [PUBMED:16461286] [PUBMED:10779358] [PUBMED:18003747] [PUBMED:15923660] [PUBMED:10642533] [PUBMED:11342560] [PUBMED:10448098] [PUBMED:11226253] [PUBMED:18490450] [PUBMED:19193766] [PUBMED:10913124] [PUBMED:10811902] [PUBMED:17077126] [PUBMED:11533043] [PUBMED:12447393] [PUBMED:10333475] [PUBMED:9550703] [PUBMED:10075920] [PUBMED:9417041] [PUBMED:17719203] [PUBMED:14625293] [PUBMED:17122362] [PUBMED:17846866]
Atypical NF-kappaB pathway [NCBI:137946] [Pathway Interaction Database:nfkappabatypicalpathway] [PUBMED:1501714] [PUBMED:9892650] [PUBMED:16308565] [PUBMED:14534291] [PUBMED:8330739] [PUBMED:8622692] [PUBMED:9724653] [PUBMED:1639070] [PUBMED:8668171] [PUBMED:8404857] [PUBMED:12711606] [PUBMED:12429743] [PUBMED:14580335] [PUBMED:12870650]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Beta-catenin independent WNT signaling [NCBI:1269610] [REACTOME:R-HSA-3858494] [PUBMED:22935904] [PUBMED:21903638] [PUBMED:23256519] [PUBMED:8065359] [PUBMED:7739543] [PUBMED:23140633]
CXCR4-mediated signaling events [NCBI:137910] [Pathway Interaction Database:cxcr4_pathway] [PUBMED:18799424] [PUBMED:17537990] [PUBMED:10881171] [PUBMED:17675482] [PUBMED:11157475] [PUBMED:12077227] [PUBMED:11544290] [PUBMED:8752280] [PUBMED:12535795] [PUBMED:19380820] [PUBMED:10952719] [PUBMED:16230460] [PUBMED:12682230] [PUBMED:16503409] [PUBMED:10644702] [PUBMED:9722546] [PUBMED:11784854] [PUBMED:10491003] [PUBMED:10521508] [PUBMED:10606629] [PUBMED:15615703] [PUBMED:17568820] [PUBMED:10753828] [PUBMED:12519755] [PUBMED:12032308] [PUBMED:8752281] [PUBMED:10570282] [PUBMED:11369622] [PUBMED:15728464] [PUBMED:12590707] [PUBMED:16038794] [PUBMED:14662753] [PUBMED:18596232] [PUBMED:17056591] [PUBMED:14602072] [PUBMED:15994292] [PUBMED:16919488] [PUBMED:15872091] [PUBMED:10506573] [PUBMED:12036857] [PUBMED:15618472] [PUBMED:14704365] [PUBMED:18227351] [PUBMED:11641392] [PUBMED:18319399] [PUBMED:12133960] [PUBMED:15630457]
Cargo recognition for clathrin-mediated endocytosis [NCBI:1427859] [REACTOME:R-HSA-8856825] [PUBMED:24186068] [PUBMED:12952941] [PUBMED:19696796] [PUBMED:14985334] [PUBMED:20448150] [PUBMED:20485680] [PUBMED:16382132] [PUBMED:23482940] [PUBMED:16870701]
Chemokine signaling pathway [NCBI:99051] [KEGG:hsa04062] [PUBMED:17371236] [PUBMED:19159344] [PUBMED:17169327] [PUBMED:10852130] [PUBMED:9765254] [PUBMED:15771581] [PUBMED:14607270] [PUBMED:18662984] [PUBMED:12495636] [PUBMED:15803148] [PUBMED:15046611] [PUBMED:12069927] [PUBMED:18711432] [PUBMED:17675482] [PUBMED:16144840] [PUBMED:17496928] [PUBMED:17537990] [PUBMED:11872087] [PUBMED:12051620] [PUBMED:14625285] [PUBMED:8576262] [PUBMED:11244042]
Clathrin-mediated endocytosis [NCBI:1427858] [REACTOME:R-HSA-8856828] [PUBMED:16516836] [PUBMED:15339664] [PUBMED:19754444] [PUBMED:8552632] [PUBMED:21779028] [PUBMED:12353027] [PUBMED:23891661] [PUBMED:21613550] [PUBMED:20059951] [PUBMED:21447041] [PUBMED:17620409] [PUBMED:16903783] [PUBMED:21445324] [PUBMED:19696798] [PUBMED:26246598] [PUBMED:25085911] [PUBMED:24186068] [PUBMED:26829388] [PUBMED:27092250] [PUBMED:24581490] [PUBMED:26042225] [PUBMED:23823722] [PUBMED:24789820] [PUBMED:9736607] [PUBMED:23637288] [PUBMED:22233676] [PUBMED:19458185] [PUBMED:26403691] [PUBMED:19296720] [PUBMED:15703209] [PUBMED:20428113] [PUBMED:8953040] [PUBMED:1177317] [PUBMED:9092476] [PUBMED:26872272] [PUBMED:19092055]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
Deubiquitination [NCBI:1427860] [REACTOME:R-HSA-5688426] [PUBMED:19243136] [PUBMED:20074029] [PUBMED:15571815] [PUBMED:20418328] [PUBMED:16325574] [PUBMED:12944365] [PUBMED:23845989] [PUBMED:22201797]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Dopaminergic synapse [NCBI:469199] [KEGG:hsa04728] [PUBMED:20727368] [PUBMED:10433257] [PUBMED:17408758] [PUBMED:15292232] [PUBMED:9457173] [PUBMED:17349698] [PUBMED:15521361] [PUBMED:18353279] [PUBMED:21303898] [PUBMED:19251795] [PUBMED:15381316] [PUBMED:15590733] [PUBMED:20224735] [PUBMED:19138563] [PUBMED:12967774]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
FCERI mediated MAPK activation [NCBI:1269299] [REACTOME:R-HSA-2871796] [PUBMED:19290926] [PUBMED:19909365] [PUBMED:17122878]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:15099567] [PUBMED:21799019]
Frs2-mediated activation [NCBI:1269470] [REACTOME:R-HSA-170968] [PUBMED:9069267]
G alpha (s) signalling events [NCBI:1269575] [REACTOME:R-HSA-418555] [PUBMED:12036966]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GRB2 events in EGFR signaling [NCBI:1269382] [REACTOME:R-HSA-179812] [PUBMED:11706405] [PUBMED:11498013]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
Hedgehog 'on' state [NCBI:1269640] [REACTOME:R-HSA-5632684] [PUBMED:23719536] [PUBMED:21502959] [PUBMED:21801010] [PUBMED:20395968]
Hedgehog signaling events mediated by Gli proteins [NCBI:137912] [Pathway Interaction Database:hedgehog_glipathway] [PUBMED:14611647] [PUBMED:16908539] [PUBMED:16885213] [PUBMED:16459297] [PUBMED:15087129] [PUBMED:10075717] [PUBMED:10725236] [PUBMED:10564661] [PUBMED:15215207] [PUBMED:16611981] [PUBMED:16364285] [PUBMED:11748151] [PUBMED:16537363] [PUBMED:10531011] [PUBMED:11449277] [PUBMED:12812795] [PUBMED:16424016] [PUBMED:14723851] [PUBMED:10693759] [PUBMED:15545630] [PUBMED:16254602] [PUBMED:14603322] [PUBMED:16061793] [PUBMED:10559945] [PUBMED:16740475] [PUBMED:16705181] [PUBMED:9636069] [PUBMED:10806483] [PUBMED:11960000] [PUBMED:15930098]
Hedgehog signaling pathway [NCBI:83063] [KEGG:hsa04340] [PUBMED:22534646] [PUBMED:26077918] [PUBMED:24925320] [PUBMED:23719536] [PUBMED:26064136] [PUBMED:26366162] [PUBMED:20708941] [PUBMED:22056910] [PUBMED:18583599] [PUBMED:23799571] [PUBMED:26875496]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
IGF1R signaling cascade [NCBI:1269618] [REACTOME:R-HSA-2428924] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959]
IRS-mediated signalling [NCBI:1269431] [REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R [NCBI:1269620] [REACTOME:R-HSA-2428928] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:18927274] [PUBMED:21042815] [PUBMED:20098959]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Insulin receptor signalling cascade [NCBI:1269429] [REACTOME:R-HSA-74751] [PUBMED:9677303] [PUBMED:11282018]
Interleukin receptor SHC signaling [NCBI:1269322] [REACTOME:R-HSA-912526] [PUBMED:8294403]
Interleukin-2 signaling [NCBI:1269321] [REACTOME:R-HSA-451927] [PUBMED:17936914] [PUBMED:18817510] [PUBMED:19543225] [PUBMED:18062768]
Interleukin-3, 5 and GM-CSF signaling [NCBI:1269323] [REACTOME:R-HSA-512988] [PUBMED:10450743] [PUBMED:9766809]
MAP2K and MAPK activation [NCBI:1269287] [REACTOME:R-HSA-5674135] [PUBMED:21779496] [PUBMED:20674547] [PUBMED:22569528] [PUBMED:22177953] [PUBMED:19091303]
MAPK family signaling cascades [NCBI:1269501] [REACTOME:R-HSA-5683057] [PUBMED:21167873] [PUBMED:17161475] [PUBMED:22535895] [PUBMED:21372320]
MAPK signaling pathway [NCBI:83048] [KEGG:hsa04010] [PUBMED:11749383] [PUBMED:12566928] [PUBMED:12849693] [PUBMED:12676795] [PUBMED:12947395] [PUBMED:14597384] [PUBMED:11369511] [PUBMED:12191611] [PUBMED:12390245]
MAPK1/MAPK3 signaling [NCBI:1269502] [REACTOME:R-HSA-5684996] [PUBMED:25378393] [PUBMED:18199641] [PUBMED:17496909] [PUBMED:21779496] [PUBMED:15520807] [PUBMED:16393692] [PUBMED:19520853] [PUBMED:17496910] [PUBMED:22569528]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Morphine addiction [NCBI:552665] [KEGG:hsa05032] [PUBMED:8785060] [PUBMED:16581089] [PUBMED:21872647] [PUBMED:14625081] [PUBMED:20962224] [PUBMED:15661627] [PUBMED:1346804] [PUBMED:12859419] [PUBMED:8096779] [PUBMED:18349442] [PUBMED:21930931] [PUBMED:10066284] [PUBMED:14969742] [PUBMED:8987801] [PUBMED:12217944] [PUBMED:11750924] [PUBMED:11152760]
NCAM signaling for neurite out-growth [NCBI:1270312] [REACTOME:R-HSA-375165] [PUBMED:18760361] [PUBMED:12587671] [PUBMED:15662836] [PUBMED:17975827] [PUBMED:15153429] [PUBMED:12700044]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Nephrin/Neph1 signaling in the kidney podocyte [NCBI:138072] [Pathway Interaction Database:nephrin_neph1_pathway] [PUBMED:12660326] [PUBMED:18212058] [PUBMED:12832477] [PUBMED:10504499] [PUBMED:12846735] [PUBMED:18385666] [PUBMED:12668668] [PUBMED:19142224] [PUBMED:14633607] [PUBMED:16525419] [PUBMED:10514378] [PUBMED:17923684] [PUBMED:18274541] [PUBMED:17079490] [PUBMED:11733557] [PUBMED:16968782] [PUBMED:15200416] [PUBMED:12424224] [PUBMED:11562357] [PUBMED:18715943] [PUBMED:11549599] [PUBMED:15339792] [PUBMED:10742096] [PUBMED:14570703] [PUBMED:19179337] [PUBMED:19497968] [PUBMED:12578837] [PUBMED:18562307] [PUBMED:18046313] [PUBMED:12646566] [PUBMED:15579503] [PUBMED:18033240] [PUBMED:16543952]
Noncanonical Wnt signaling pathway [NCBI:169354] [Pathway Interaction Database:wnt_noncanonical_pathway] [PUBMED:11408485] [PUBMED:20457807] [PUBMED:17646398] [PUBMED:15509575] [PUBMED:10391247] [PUBMED:12482967] [PUBMED:10777564] [PUBMED:19720827] [PUBMED:18667433] [PUBMED:18162551] [PUBMED:18215320] [PUBMED:17101698] [PUBMED:12839624] [PUBMED:19910923] [PUBMED:10395542] [PUBMED:15121866] [PUBMED:11779461] [PUBMED:16880514] [PUBMED:18606138] [PUBMED:12771126] [PUBMED:18615587] [PUBMED:17952062]
Olfactory transduction [NCBI:83087] [KEGG:hsa04740] [PUBMED:19652915] [PUBMED:22735517] [PUBMED:11557990] [PUBMED:19306880] [PUBMED:16269360] [PUBMED:19941039] [PUBMED:20145624] [PUBMED:12488531] [PUBMED:22875451] [PUBMED:24733839] [PUBMED:10944513]
Oncogenic MAPK signaling [NCBI:1457781] [REACTOME:R-HSA-6802957] [PUBMED:25907612] [PUBMED:24651010] [PUBMED:24202393] [PUBMED:25435214] [PUBMED:21993244] [PUBMED:24814062] [PUBMED:22589270]
PCP/CE pathway [NCBI:1269611] [REACTOME:R-HSA-4086400] [PUBMED:23140633] [PUBMED:18848778] [PUBMED:10811221] [PUBMED:19365405] [PUBMED:9598355] [PUBMED:21983142] [PUBMED:17433286] [PUBMED:20004982] [PUBMED:19204114]
Paradoxical activation of RAF signaling by kinase inactive BRAF [NCBI:1457785] [REACTOME:R-HSA-6802955] [PUBMED:25435214] [PUBMED:20674547] [PUBMED:24957944] [PUBMED:23352452] [PUBMED:20130576] [PUBMED:23680146] [PUBMED:16364920] [PUBMED:25907612] [PUBMED:15035987] [PUBMED:20179705] [PUBMED:19727074] [PUBMED:20141835] [PUBMED:22510884]
Platelet activation, signaling and aggregation [NCBI:1269350] [REACTOME:R-HSA-76002] [PUBMED:16543958] [PUBMED:8704248] [PUBMED:2018971] [PUBMED:1672265] [PUBMED:17059469] [PUBMED:12681240] [PUBMED:12411949] [PUBMED:11511514]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Prolonged ERK activation events [NCBI:1269469] [REACTOME:R-HSA-169893] [PUBMED:12765839] [PUBMED:9069267]
RAF/MAP kinase cascade [NCBI:1269285] [REACTOME:R-HSA-5673001] [PUBMED:21167873] [PUBMED:24937142] [PUBMED:20674547] [PUBMED:17496910] [PUBMED:22177953] [PUBMED:17496919] [PUBMED:22569528] [PUBMED:22535895] [PUBMED:12068308] [PUBMED:17496923] [PUBMED:19091303] [PUBMED:21372320] [PUBMED:21388974] [PUBMED:15520807]
RET signaling [NCBI:1427866] [REACTOME:R-HSA-8853659] [PUBMED:15013219] [PUBMED:17036197]
SHC1 events in EGFR signaling [NCBI:1269383] [REACTOME:R-HSA-180336] [PUBMED:11498013] [PUBMED:8755247]
SOS-mediated signalling [NCBI:1269440] [REACTOME:R-HSA-112412]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by BRAF and RAF fusions [NCBI:1457786] [REACTOME:R-HSA-6802952] [PUBMED:18974108] [PUBMED:24135138] [PUBMED:22745804] [PUBMED:25907612] [PUBMED:20526349] [PUBMED:15630448] [PUBMED:25204415] [PUBMED:24345920] [PUBMED:21424530] [PUBMED:23583981]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Hedgehog [NCBI:1269633] [REACTOME:R-HSA-5358351] [PUBMED:19081070] [PUBMED:21801010] [PUBMED:15549094] [PUBMED:23719536]
Signaling by Insulin receptor [NCBI:1269428] [REACTOME:R-HSA-74752] [PUBMED:8276779]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Signaling by Leptin [NCBI:1269632] [REACTOME:R-HSA-2586552] [PUBMED:22211890] [PUBMED:23562747] [PUBMED:20600241] [PUBMED:21622208] [PUBMED:23579596] [PUBMED:22458591] [PUBMED:21489811] [PUBMED:19724019] [PUBMED:21331644] [PUBMED:22448029] [PUBMED:21147620] [PUBMED:20198122] [PUBMED:21677426] [PUBMED:20029269] [PUBMED:22249808] [PUBMED:22991412] [PUBMED:21527729] [PUBMED:17937601] [PUBMED:20553370] [PUBMED:21713385] [PUBMED:23565489] [PUBMED:22289780]
Signaling by NOTCH [NCBI:1269530] [REACTOME:R-HSA-157118]
Signaling by NOTCH1 [NCBI:1269535] [REACTOME:R-HSA-1980143] [PUBMED:20972443] [PUBMED:8649374] [PUBMED:11740940] [PUBMED:15965470] [PUBMED:16284625] [PUBMED:9694793] [PUBMED:19567869] [PUBMED:12354787] [PUBMED:11585921] [PUBMED:20418862] [PUBMED:11226752] [PUBMED:9590294] [PUBMED:9315665] [PUBMED:17114293] [PUBMED:18094723] [PUBMED:10964718] [PUBMED:10879540] [PUBMED:8001118] [PUBMED:12050117] [PUBMED:18043734] [PUBMED:9819428] [PUBMED:15824097] [PUBMED:9244301] [PUBMED:16256737] [PUBMED:8687460] [PUBMED:19726682] [PUBMED:8313469] [PUBMED:15574878] [PUBMED:18296446] [PUBMED:16530044] [PUBMED:9620803] [PUBMED:18237417] [PUBMED:7566092] [PUBMED:18628966] [PUBMED:12391150] [PUBMED:12530964] [PUBMED:11006133] [PUBMED:18374649] [PUBMED:15107403] [PUBMED:18077452] [PUBMED:15652348] [PUBMED:15546612] [PUBMED:10882063] [PUBMED:14980219] [PUBMED:10713164] [PUBMED:9462510] [PUBMED:11461910] [PUBMED:14567914] [PUBMED:17003037] [PUBMED:17028573] [PUBMED:11044625] [PUBMED:10206645] [PUBMED:19524514]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signaling by RAS mutants [NCBI:1457782] [REACTOME:R-HSA-6802949] [PUBMED:21993244] [PUBMED:22589270] [PUBMED:24651010]
Signaling by SCF-KIT [NCBI:1269487] [REACTOME:R-HSA-1433557] [PUBMED:17350321] [PUBMED:16483568] [PUBMED:7688988] [PUBMED:19540337] [PUBMED:16475976] [PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) [NCBI:1269617] [REACTOME:R-HSA-2404192] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22044904] [PUBMED:22649417]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
Signaling by high-kinase activity BRAF mutants [NCBI:1457783] [REACTOME:R-HSA-6802948] [PUBMED:16702958] [PUBMED:21190184] [PUBMED:23352452] [PUBMED:16364920] [PUBMED:22113612] [PUBMED:12068308] [PUBMED:15035987] [PUBMED:22510884] [PUBMED:25435214] [PUBMED:24202393]
Signaling by moderate kinase activity BRAF mutants [NCBI:1457784] [REACTOME:R-HSA-6802946] [PUBMED:25907612] [PUBMED:15035987] [PUBMED:24202393] [PUBMED:22510884] [PUBMED:25355519] [PUBMED:23352452]
Signaling events mediated by the Hedgehog family [NCBI:137950] [Pathway Interaction Database:hedgehog_2pathway] [PUBMED:8906794] [PUBMED:16647303] [PUBMED:12917290] [PUBMED:12192414] [PUBMED:12421714] [PUBMED:7891723] [PUBMED:16136078] [PUBMED:10984056] [PUBMED:16229832] [PUBMED:15019948] [PUBMED:11934857] [PUBMED:11572986] [PUBMED:16537363] [PUBMED:16647304] [PUBMED:9811851] [PUBMED:11668681] [PUBMED:9593755] [PUBMED:15618519] [PUBMED:16895439] [PUBMED:12123571] [PUBMED:10050855] [PUBMED:11517919] [PUBMED:12372301] [PUBMED:16284117] [PUBMED:10465785] [PUBMED:11964399] [PUBMED:11027307] [PUBMED:8824192] [PUBMED:11486055]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
Signalling to ERKs [NCBI:1269464] [REACTOME:R-HSA-187687] [PUBMED:10508738]
Signalling to RAS [NCBI:1269465] [REACTOME:R-HSA-167044] [PUBMED:11520933]
Signalling to p38 via RIT and RIN [NCBI:1269468] [REACTOME:R-HSA-187706] [PUBMED:10712923]
TGF-beta receptor signaling [NCBI:138024] [Pathway Interaction Database:tgfbrpathway] [PUBMED:12118366] [PUBMED:8242743] [PUBMED:15221015] [PUBMED:9335507] [PUBMED:11278302] [PUBMED:16601693] [PUBMED:8391934] [PUBMED:1333888] [PUBMED:11438668] [PUBMED:17327236] [PUBMED:2879635] [PUBMED:11483955] [PUBMED:12717440] [PUBMED:8047140] [PUBMED:8576253] [PUBMED:9865696] [PUBMED:9346908] [PUBMED:17197390] [PUBMED:8533096] [PUBMED:8756725] [PUBMED:10615055] [PUBMED:10934479] [PUBMED:16251192] [PUBMED:7706248] [PUBMED:15946939] [PUBMED:7774578] [PUBMED:7988555] [PUBMED:11278251] [PUBMED:11027280] [PUBMED:17420258] [PUBMED:9169454] [PUBMED:12151385] [PUBMED:10757800] [PUBMED:12543979] [PUBMED:12475967] [PUBMED:9679059] [PUBMED:17673906] [PUBMED:9774674] [PUBMED:8893010] [PUBMED:1544886] [PUBMED:12958365] [PUBMED:12110587] [PUBMED:9233797] [PUBMED:11163210] [PUBMED:15496141] [PUBMED:7693660] [PUBMED:14657019] [PUBMED:12429842] [PUBMED:11124802] [PUBMED:11389444] [PUBMED:8798398] [PUBMED:15356634] [PUBMED:17272273] [PUBMED:1657407] [PUBMED:12589052] [PUBMED:11016919] [PUBMED:14718519] [PUBMED:10777621] [PUBMED:17384642] [PUBMED:1310899] [PUBMED:9856985] [PUBMED:10519551] [PUBMED:9155023] [PUBMED:12134160] [PUBMED:9215638] [PUBMED:12134149] [PUBMED:16157589] [PUBMED:12356868] [PUBMED:11387212] [PUBMED:12034739] [PUBMED:11739411] [PUBMED:15761148] [PUBMED:9463378] [PUBMED:11583628] [PUBMED:15684397] [PUBMED:8947046] [PUBMED:11781097]
Thrombin signalling through proteinase activated receptors (PARs) [NCBI:1269356] [REACTOME:R-HSA-456926] [PUBMED:11001069]
Thromboxane A2 receptor signaling [NCBI:138060] [Pathway Interaction Database:txa2pathway] [PUBMED:15100160] [PUBMED:11160627] [PUBMED:16859489] [PUBMED:7476920] [PUBMED:12193606] [PUBMED:8474027] [PUBMED:16595906] [PUBMED:11748077] [PUBMED:8948507] [PUBMED:11055976] [PUBMED:15884057] [PUBMED:1825698] [PUBMED:9054415] [PUBMED:1851174] [PUBMED:9862451] [PUBMED:11901221] [PUBMED:14976202] [PUBMED:9915793] [PUBMED:12796499] [PUBMED:16212421] [PUBMED:16956790] [PUBMED:8034687] [PUBMED:17466390] [PUBMED:12183468] [PUBMED:10085139] [PUBMED:9649216] [PUBMED:11873244] [PUBMED:12038794] [PUBMED:10771086] [PUBMED:11015313] [PUBMED:9417126] [PUBMED:12626493] [PUBMED:10827090] [PUBMED:7969066] [PUBMED:8119906] [PUBMED:11389977] [PUBMED:16876780] [PUBMED:16126723] [PUBMED:8636072] [PUBMED:8894620] [PUBMED:11526402] [PUBMED:17229546] [PUBMED:10037795] [PUBMED:15845539] [PUBMED:10670835] [PUBMED:14530262] [PUBMED:8290554] [PUBMED:11443056] [PUBMED:10800962] [PUBMED:9560198] [PUBMED:11389883] [PUBMED:7961988] [PUBMED:10212262] [PUBMED:8245033] [PUBMED:8613548] [PUBMED:7591017] [PUBMED:12187125] [PUBMED:11516166] [PUBMED:10318854]
Ub-specific processing proteases [NCBI:1427862] [REACTOME:R-HSA-5689880] [PUBMED:16325574]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:17344076] [PUBMED:16633338] [PUBMED:19230644] [PUBMED:13678960]
VEGFR2 mediated cell proliferation [NCBI:1269485] [REACTOME:R-HSA-5218921] [PUBMED:22866201] [PUBMED:22180219] [PUBMED:22762016]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]
WNT5A-dependent internalization of FZD4 [NCBI:1269613] [REACTOME:R-HSA-5099900] [PUBMED:12958364] [PUBMED:20947020] [PUBMED:17199046]