full name
phospholipase D2

synonyms
PLD2, ENSG00000129219

HGNC
HGNC:9068

Entrez Gene
Gene:5338

ENSEMBL
ENSG00000129219

location
chr: 17
start: 4710396
stop: 4726727
strand: +

transcripts
NM_002663.4
NM_001243108.1

pathways
Alpha-synuclein signaling [NCBI:137913] [Pathway Interaction Database:alphasynuclein_pathway] [PUBMED:12551928] [PUBMED:15671022] [PUBMED:12887682] [PUBMED:14991825] [PUBMED:11431533] [PUBMED:11588587] [PUBMED:16030137] [PUBMED:15845543] [PUBMED:11590439] [PUBMED:12096713] [PUBMED:11687285] [PUBMED:15978696] [PUBMED:10407019] [PUBMED:11078745] [PUBMED:16403519] [PUBMED:14985429] [PUBMED:14645218] [PUBMED:12787066] [PUBMED:11292651] [PUBMED:12421356] [PUBMED:15944382] [PUBMED:10567343] [PUBMED:11744621] [PUBMED:15935068] [PUBMED:12928483] [PUBMED:11821392] [PUBMED:10852916]
Angiopoietin receptor Tie2-mediated signaling [NCBI:137917] [Pathway Interaction Database:angiopoietinreceptor_pathway] [PUBMED:9204896] [PUBMED:12609966] [PUBMED:14726409] [PUBMED:11157678] [PUBMED:10347092] [PUBMED:11967990] [PUBMED:15162796] [PUBMED:11289054] [PUBMED:12759249] [PUBMED:10051567] [PUBMED:12824293] [PUBMED:16895971] [PUBMED:10807867] [PUBMED:12933576] [PUBMED:11513602] [PUBMED:12074640] [PUBMED:8980223] [PUBMED:14665640] [PUBMED:15132996] [PUBMED:10944458] [PUBMED:11230987] [PUBMED:15242771] [PUBMED:10585289] [PUBMED:16061664] [PUBMED:10376602] [PUBMED:15350545] [PUBMED:9632797] [PUBMED:10625301] [PUBMED:9926914] [PUBMED:17189382] [PUBMED:11139469] [PUBMED:11689432] [PUBMED:11416142] [PUBMED:11166279] [PUBMED:15284220] [PUBMED:15985432] [PUBMED:16049136] [PUBMED:16157706] [PUBMED:10521483] [PUBMED:12816861] [PUBMED:9478921] [PUBMED:10376603] [PUBMED:15769741] [PUBMED:12890486] [PUBMED:14749497] [PUBMED:7561682] [PUBMED:11801735] [PUBMED:12665569] [PUBMED:12117724] [PUBMED:9764820]
Arf1 pathway [NCBI:137927] [Pathway Interaction Database:arf_3pathway] [PUBMED:11346801] [PUBMED:9694811] [PUBMED:9819391] [PUBMED:12376537] [PUBMED:8498538] [PUBMED:9405360] [PUBMED:11301005] [PUBMED:15793564] [PUBMED:11970962] [PUBMED:8530346] [PUBMED:10747089] [PUBMED:10212200] [PUBMED:9388229] [PUBMED:7961749] [PUBMED:10652308] [PUBMED:15781476] [PUBMED:11342560] [PUBMED:16100119] [PUBMED:9826657] [PUBMED:15202998] [PUBMED:10848997] [PUBMED:8144664] [PUBMED:9268368]
Arf6 downstream pathway [NCBI:138038] [Pathway Interaction Database:arf6downstreampathway] [PUBMED:12388770] [PUBMED:14565977] [PUBMED:10036235] [PUBMED:14764880] [PUBMED:12447393] [PUBMED:9312003] [PUBMED:17077126] [PUBMED:17363898] [PUBMED:14505574] [PUBMED:16280360] [PUBMED:17628206] [PUBMED:15601896] [PUBMED:10913182] [PUBMED:16452216] [PUBMED:7753201] [PUBMED:15210957] [PUBMED:16880525] [PUBMED:16181626] [PUBMED:17640372] [PUBMED:11481345] [PUBMED:17409355] [PUBMED:12379803] [PUBMED:18084281] [PUBMED:10589680] [PUBMED:11532961] [PUBMED:17353194] [PUBMED:8769418] [PUBMED:10779358] [PUBMED:18026091] [PUBMED:12509462] [PUBMED:15087504] [PUBMED:9664047]
Arf6 trafficking events [NCBI:137954] [Pathway Interaction Database:arf6_traffickingpathway] [PUBMED:10748097] [PUBMED:15590645] [PUBMED:15980073] [PUBMED:19644450] [PUBMED:16461286] [PUBMED:14675422] [PUBMED:16139226] [PUBMED:12589044] [PUBMED:15802264] [PUBMED:14585928] [PUBMED:17664335] [PUBMED:17719203] [PUBMED:12960436] [PUBMED:12447393] [PUBMED:11535619] [PUBMED:12657640] [PUBMED:16280360] [PUBMED:9314528] [PUBMED:19211056] [PUBMED:11533043] [PUBMED:12847086] [PUBMED:15146059] [PUBMED:9685333] [PUBMED:12925709] [PUBMED:15231847] [PUBMED:12810696] [PUBMED:14662749] [PUBMED:16030257] [PUBMED:12379803] [PUBMED:15775968] [PUBMED:11532961] [PUBMED:8769418]
Choline metabolism in cancer [NCBI:1059539] [KEGG:hsa05231] [PUBMED:23076158] [PUBMED:19264150] [PUBMED:16230400] [PUBMED:23350810] [PUBMED:22429397] [PUBMED:16432178] [PUBMED:19136975] [PUBMED:22089420] [PUBMED:14517341] [PUBMED:22921309] [PUBMED:19855431] [PUBMED:20528734] [PUBMED:19935796] [PUBMED:14523987] [PUBMED:21793073]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
ErbB1 downstream signaling [NCBI:138057] [Pathway Interaction Database:erbb1_downstream_pathway] [PUBMED:1330321] [PUBMED:7939666] [PUBMED:9448004] [PUBMED:3497813] [PUBMED:7680434] [PUBMED:18567582] [PUBMED:12503606] [PUBMED:12183455] [PUBMED:8073291] [PUBMED:17563371] [PUBMED:8378775] [PUBMED:19219045] [PUBMED:1990291] [PUBMED:15550174] [PUBMED:16508002] [PUBMED:17881733] [PUBMED:11278353] [PUBMED:9889102] [PUBMED:14699061] [PUBMED:8248196] [PUBMED:8262053] [PUBMED:11319218] [PUBMED:19595761] [PUBMED:17360704] [PUBMED:15048123] [PUBMED:19341767] [PUBMED:9837959] [PUBMED:14993287] [PUBMED:19710016] [PUBMED:18516090] [PUBMED:9733714] [PUBMED:8052307] [PUBMED:10567369] [PUBMED:9335504] [PUBMED:9580112] [PUBMED:11018520] [PUBMED:10499589] [PUBMED:19706684] [PUBMED:8910287] [PUBMED:10469645] [PUBMED:11073940] [PUBMED:9315636] [PUBMED:2189103] [PUBMED:14765121] [PUBMED:14970219] [PUBMED:8332195] [PUBMED:16239230] [PUBMED:8621729] [PUBMED:11889038] [PUBMED:11029289] [PUBMED:11152283] [PUBMED:8071311] [PUBMED:12932319] [PUBMED:19541618] [PUBMED:2123453] [PUBMED:9384584] [PUBMED:8140422] [PUBMED:10644690] [PUBMED:18156174] [PUBMED:15718470] [PUBMED:12172553] [PUBMED:10082559] [PUBMED:17079732] [PUBMED:12446727] [PUBMED:9989263] [PUBMED:12551925] [PUBMED:10856237] [PUBMED:8013650] [PUBMED:7600581] [PUBMED:8688081] [PUBMED:8397445] [PUBMED:16135787] [PUBMED:7637810] [PUBMED:9438848] [PUBMED:12515821] [PUBMED:12881422] [PUBMED:9305638] [PUBMED:15284024] [PUBMED:3136398] [PUBMED:10597268] [PUBMED:10648629] [PUBMED:9790194] [PUBMED:9797479] [PUBMED:16093354] [PUBMED:7741752] [PUBMED:10891480] [PUBMED:17052213] [PUBMED:8221888] [PUBMED:9593664] [PUBMED:16892053] [PUBMED:8413226] [PUBMED:9407138] [PUBMED:9710644] [PUBMED:8248197] [PUBMED:12414794] [PUBMED:1653949] [PUBMED:12181570] [PUBMED:9550702] [PUBMED:12110590] [PUBMED:10400627] [PUBMED:9927426] [PUBMED:12242303] [PUBMED:10480933] [PUBMED:9665134] [PUBMED:11238956] [PUBMED:16984645] [PUBMED:7761091] [PUBMED:17322878] [PUBMED:12640115] [PUBMED:14963038] [PUBMED:17486115] [PUBMED:8503013] [PUBMED:16155590] [PUBMED:16628218] [PUBMED:1406636] [PUBMED:9430728] [PUBMED:19401591] [PUBMED:17053785] [PUBMED:7992057] [PUBMED:14609431] [PUBMED:9346240] [PUBMED:8626780] [PUBMED:8940018] [PUBMED:12454019] [PUBMED:10441128] [PUBMED:14747473] [PUBMED:11777939] [PUBMED:8614832] [PUBMED:8378774] [PUBMED:19121340] [PUBMED:18775988] [PUBMED:15039778] [PUBMED:9770464] [PUBMED:10567531] [PUBMED:8180183] [PUBMED:10675331] [PUBMED:1545823] [PUBMED:7958858] [PUBMED:11948693] [PUBMED:2109185] [PUBMED:8942998] [PUBMED:1637333] [PUBMED:14690430] [PUBMED:11134016] [PUBMED:12429840] [PUBMED:8621573] [PUBMED:7600582] [PUBMED:8226933] [PUBMED:10201527] [PUBMED:12832467] [PUBMED:3492494] [PUBMED:15034142] [PUBMED:9596579] [PUBMED:7889942] [PUBMED:8524316] [PUBMED:7731720] [PUBMED:8386592] [PUBMED:16407412] [PUBMED:6334806] [PUBMED:11703925] [PUBMED:11099046] [PUBMED:7876145] [PUBMED:14498832]
Ether lipid metabolism [NCBI:82990] [KEGG:hsa00565] [PUBMED:11015622] [PUBMED:11275267] [PUBMED:15788404]
Fc gamma R-mediated phagocytosis [NCBI:114228] [KEGG:hsa04666] [PUBMED:11304556] [PUBMED:11244038] [PUBMED:10755615] [PUBMED:17308335] [PUBMED:12821647] [PUBMED:15466916] [PUBMED:17050193] [PUBMED:11228151] [PUBMED:12488490] [PUBMED:10224668] [PUBMED:11708889] [PUBMED:9581795] [PUBMED:10586078] [PUBMED:9417101] [PUBMED:15485887] [PUBMED:18322649] [PUBMED:10577498] [PUBMED:10376013] [PUBMED:10601359] [PUBMED:9545263]
Fc-epsilon receptor I signaling in mast cells [NCBI:138050] [Pathway Interaction Database:fcer1pathway] [PUBMED:9556577] [PUBMED:8629002] [PUBMED:12217401] [PUBMED:15010370] [PUBMED:15608142] [PUBMED:7561053] [PUBMED:7537741] [PUBMED:7963537] [PUBMED:8947047] [PUBMED:1384468] [PUBMED:14757742] [PUBMED:16174756] [PUBMED:10583594] [PUBMED:7513150] [PUBMED:12089510] [PUBMED:10811803] [PUBMED:9268346] [PUBMED:12640123] [PUBMED:9108083] [PUBMED:8602265] [PUBMED:11340169] [PUBMED:12953098] [PUBMED:11465115] [PUBMED:7730640] [PUBMED:9550384] [PUBMED:7518558] [PUBMED:11137136] [PUBMED:15282299] [PUBMED:14634134] [PUBMED:8534912] [PUBMED:16002993] [PUBMED:12192036] [PUBMED:7608202] [PUBMED:11714805] [PUBMED:11970986] [PUBMED:10903718] [PUBMED:15265912] [PUBMED:15477350]
Fcgamma receptor (FCGR) dependent phagocytosis [NCBI:1269279] [REACTOME:R-HSA-2029480] [PUBMED:8541526] [PUBMED:12488490] [PUBMED:16413920] [PUBMED:17050193]
Glutamatergic synapse [NCBI:213818] [KEGG:hsa04724] [PUBMED:10481192] [PUBMED:11561058] [PUBMED:18425072] [PUBMED:17706608] [PUBMED:20055706] [PUBMED:19112153] [PUBMED:17663464] [PUBMED:19110202] [PUBMED:19559598] [PUBMED:9665875] [PUBMED:11672421] [PUBMED:18464791] [PUBMED:12399578] [PUBMED:14684436]
Glycerophospholipid biosynthesis [NCBI:1270054] [REACTOME:R-HSA-1483206] [PUBMED:21220505] [PUBMED:19703651] [PUBMED:20823909] [PUBMED:21683693] [PUBMED:21382416] [PUBMED:21704024]
Glycerophospholipid metabolism [NCBI:82989] [KEGG:hsa00564] [PUBMED:14663079] [PUBMED:15522832] [PUBMED:10938271] [PUBMED:10092508] [PUBMED:1649829] [PUBMED:10542045] [PUBMED:1512203] [PUBMED:12431977]
GnRH signaling pathway [NCBI:83091] [KEGG:hsa04912] [PUBMED:15080147] [PUBMED:15982836] [PUBMED:14596811] [PUBMED:15613448] [PUBMED:12943720] [PUBMED:10707049] [PUBMED:15350605] [PUBMED:12963732]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
LPA receptor mediated events [NCBI:137928] [Pathway Interaction Database:lysophospholipid_pathway] [PUBMED:10601262] [PUBMED:16289596] [PUBMED:7809106] [PUBMED:10342794] [PUBMED:15928312] [PUBMED:16769764] [PUBMED:11243883] [PUBMED:14688263] [PUBMED:10551845] [PUBMED:16687414] [PUBMED:9819398] [PUBMED:7527052] [PUBMED:9600933] [PUBMED:2551506] [PUBMED:15988003] [PUBMED:10644509] [PUBMED:16199135] [PUBMED:15728708] [PUBMED:1637305] [PUBMED:7476905] [PUBMED:7510708] [PUBMED:8647803] [PUBMED:10420989] [PUBMED:12880866] [PUBMED:10766839] [PUBMED:12181443] [PUBMED:15461590] [PUBMED:16452634] [PUBMED:16197369] [PUBMED:10779388] [PUBMED:10506190] [PUBMED:9305878] [PUBMED:16904289] [PUBMED:15878967] [PUBMED:15143197] [PUBMED:11948806] [PUBMED:11040035] [PUBMED:12393875] [PUBMED:9407095] [PUBMED:15280372] [PUBMED:16890224] [PUBMED:8805276]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Phospholipase D signaling pathway [NCBI:1311074] [KEGG:hsa04072] [PUBMED:9310372] [PUBMED:9119890] [PUBMED:15310762] [PUBMED:18936782] [PUBMED:24990952] [PUBMED:14769825] [PUBMED:21936578] [PUBMED:10666319] [PUBMED:17210675] [PUBMED:19264150] [PUBMED:23076158] [PUBMED:17054901] [PUBMED:16622417] [PUBMED:10807766] [PUBMED:12217395] [PUBMED:11042115] [PUBMED:19815110] [PUBMED:24995811] [PUBMED:16143829] [PUBMED:8135758] [PUBMED:11991733] [PUBMED:19410013] [PUBMED:17245604]
Phospholipid metabolism [NCBI:1270053] [REACTOME:R-HSA-1483257] [PUBMED:9242906]
Ras signaling pathway [NCBI:868085] [KEGG:hsa04014] [PUBMED:23506953] [PUBMED:18437264] [PUBMED:15062121] [PUBMED:22189424] [PUBMED:22233291] [PUBMED:12778136] [PUBMED:11313946] [PUBMED:17428555] [PUBMED:19091743] [PUBMED:18568040] [PUBMED:20420946] [PUBMED:12217381] [PUBMED:14663478] [PUBMED:21686117] [PUBMED:12642680] [PUBMED:21196257] [PUBMED:16869784] [PUBMED:21111786] [PUBMED:16966426] [PUBMED:10712923] [PUBMED:22020205] [PUBMED:17384584] [PUBMED:15572660] [PUBMED:18413813]
RhoA signaling pathway [NCBI:169356] [Pathway Interaction Database:rhoa_pathway] [PUBMED:8641286] [PUBMED:16705166] [PUBMED:9510209] [PUBMED:18267089] [PUBMED:15866170] [PUBMED:18303050] [PUBMED:17588931] [PUBMED:18941185] [PUBMED:16164598] [PUBMED:11238375] [PUBMED:18559669] [PUBMED:18025109] [PUBMED:16427251] [PUBMED:11122380] [PUBMED:8632828] [PUBMED:15866889] [PUBMED:9707430] [PUBMED:9456324] [PUBMED:8662509] [PUBMED:12429848] [PUBMED:9294169] [PUBMED:9042860] [PUBMED:9582304] [PUBMED:15170389] [PUBMED:10744700] [PUBMED:10893221] [PUBMED:14681219] [PUBMED:9121475] [PUBMED:8858161] [PUBMED:18309323] [PUBMED:9710582] [PUBMED:9265657] [PUBMED:19625450] [PUBMED:15068801] [PUBMED:11278519] [PUBMED:12732141] [PUBMED:9529607] [PUBMED:12600823] [PUBMED:9697773] [PUBMED:10085083] [PUBMED:12802051] [PUBMED:11018042] [PUBMED:7600583] [PUBMED:9693382] [PUBMED:12899698] [PUBMED:8702756] [PUBMED:10556088] [PUBMED:10037681] [PUBMED:1643657] [PUBMED:12034774] [PUBMED:9670022] [PUBMED:12574166] [PUBMED:12584113] [PUBMED:11877391] [PUBMED:9920882] [PUBMED:8995216] [PUBMED:7929302] [PUBMED:10428028] [PUBMED:15793569] [PUBMED:14595335] [PUBMED:10436006] [PUBMED:9482732] [PUBMED:11342553] [PUBMED:9351440]
Role of phospholipids in phagocytosis [NCBI:1269282] [REACTOME:R-HSA-2029485] [PUBMED:10224668] [PUBMED:20400677]
Sphingolipid signaling pathway [NCBI:1144995] [KEGG:hsa04071] [PUBMED:23919551] [PUBMED:21705677] [PUBMED:18675379] [PUBMED:20534702] [PUBMED:15999095] [PUBMED:16470226] [PUBMED:11001563] [PUBMED:17913601] [PUBMED:17161984] [PUBMED:22654878] [PUBMED:17438574] [PUBMED:18216770] [PUBMED:11418646] [PUBMED:10880336] [PUBMED:15451787] [PUBMED:25309325] [PUBMED:18403224]
Synthesis of PA [NCBI:1270055] [REACTOME:R-HSA-1483166] [PUBMED:21173190] [PUBMED:20705608] [PUBMED:18718904] [PUBMED:17170135] [PUBMED:12359733]
Synthesis of PG [NCBI:1270068] [REACTOME:R-HSA-1483148] [PUBMED:3718705] [PUBMED:7968268] [PUBMED:9407135]
cAMP signaling pathway [NCBI:1017634] [KEGG:hsa04024] [PUBMED:10880354] [PUBMED:9204709] [PUBMED:21693691] [PUBMED:24062645] [PUBMED:24450633] [PUBMED:21346730] [PUBMED:24613710] [PUBMED:21744067] [PUBMED:22082266] [PUBMED:16460276] [PUBMED:18176800] [PUBMED:14715909] [PUBMED:7688165] [PUBMED:24281338] [PUBMED:11117527] [PUBMED:16765984] [PUBMED:18323530] [PUBMED:18064650] [PUBMED:21852968] [PUBMED:11493633] [PUBMED:21212391] [PUBMED:15142747] [PUBMED:17077866] [PUBMED:19460777] [PUBMED:19874988] [PUBMED:16571352] [PUBMED:22022314]
mTOR signaling pathway [NCBI:83059] [KEGG:hsa04150] [NCBI:138001] [Pathway Interaction Database:mtor_4pathway] [PUBMED:17277771] [PUBMED:15341740] [PUBMED:12172553] [PUBMED:15718470] [PUBMED:14651849] [PUBMED:15268862] [PUBMED:15306821] [PUBMED:26046644] [PUBMED:12869586] [PUBMED:24556838] [PUBMED:17928295] [PUBMED:9427642] [PUBMED:18046414] [PUBMED:12912918] [PUBMED:16286006] [PUBMED:26658722] [PUBMED:24842496] [PUBMED:23465396] [PUBMED:17709744] [PUBMED:17599906] [PUBMED:16919458] [PUBMED:10364159] [PUBMED:15342917] [PUBMED:11500364] [PUBMED:19812304] [PUBMED:12482958] [PUBMED:11729323] [PUBMED:16962653] [PUBMED:18952604] [PUBMED:9465032] [PUBMED:1496022] [PUBMED:10567431] [PUBMED:19114562] [PUBMED:17510057] [PUBMED:18604198] [PUBMED:15545625] [PUBMED:11914378] [PUBMED:17461779] [PUBMED:9445476] [PUBMED:18497260] [PUBMED:12604610] [PUBMED:15071500] [PUBMED:18925875] [PUBMED:12906785] [PUBMED:11287630] [PUBMED:15004009] [PUBMED:16756488] [PUBMED:17043309] [PUBMED:18198340] [PUBMED:12820960] [PUBMED:12747827] [PUBMED:17053147] [PUBMED:15851026] [PUBMED:15467718] [PUBMED:18762023] [PUBMED:25242279] [PUBMED:24698685] [PUBMED:11175345] [PUBMED:27304501] [PUBMED:18411301] [PUBMED:11500365] [PUBMED:17693255] [PUBMED:23694989] [PUBMED:12231510] [PUBMED:19446321] [PUBMED:11418588] [PUBMED:19258318] [PUBMED:18439900] [PUBMED:19225151] [PUBMED:26185979] [PUBMED:10357815] [PUBMED:26269525] [PUBMED:23421405] [PUBMED:9271440] [PUBMED:16915281] [PUBMED:17141160] [PUBMED:15249583] [PUBMED:12912989] [PUBMED:27027448] [PUBMED:18423201] [PUBMED:19211835] [PUBMED:9204908] [PUBMED:26700098] [PUBMED:18566587] [PUBMED:17386266]
phospholipases [NCBI:142419] [BIOCYC:HUMAN_LIPASYN-PWY]