Logo
full name
arachidonate 12-lipoxygenase, 12R type

synonyms
12R-LOX, ARCI2, ALOX12B, ENSG00000179477

HGNC
HGNC:430

Entrez Gene
Gene:242

ENSEMBL
ENSG00000179477

location
chr: 17
start: 7975954
stop: 7991021
strand: -

OMIM
OMIM:603741: ALOX12B (Autosomal recessive inheritance)
OMIM:242100: Ichthyosis, congenital, autosomal recessive 2

transcripts
NM_001139.2

pathways
Arachidonic acid metabolism [NCBI:82991] [KEGG:hsa00590] [NCBI:1270087] [REACTOME:R-HSA-2142753] [PUBMED:14622984] [PUBMED:15292194] [PUBMED:10908295] [PUBMED:15205388] [PUBMED:9812980] [PUBMED:14660610] [PUBMED:11328810] [PUBMED:14636671] [PUBMED:14626496] [PUBMED:11679404] [PUBMED:19244215]
IL23-mediated signaling events [NCBI:138000] [Pathway Interaction Database:il23pathway] [PUBMED:16200068] [PUBMED:12023338] [PUBMED:17030949] [PUBMED:16670770] [PUBMED:17074928] [PUBMED:15583831] [PUBMED:16919486] [PUBMED:12417590] [PUBMED:16622035] [PUBMED:16698929] [PUBMED:14978083] [PUBMED:12610626] [PUBMED:15308705] [PUBMED:16200070] [PUBMED:15657292] [PUBMED:16648837] [PUBMED:11114383] [PUBMED:12023369] [PUBMED:9038232]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Serotonergic synapse [NCBI:525336] [KEGG:hsa04726] [PUBMED:9658404] [PUBMED:15034221] [PUBMED:11043573] [PUBMED:9651340] [PUBMED:9542727] [PUBMED:18676031] [PUBMED:12543273] [PUBMED:15710402] [PUBMED:16826372] [PUBMED:19545642] [PUBMED:11916537] [PUBMED:11701344] [PUBMED:12676358] [PUBMED:20561690] [PUBMED:16896947]
Synthesis of 12-eicosatetraenoic acid derivatives [NCBI:1270092] [REACTOME:R-HSA-2142712] [PUBMED:19244215]