full name
sterile alpha and TIR motif containing 1

synonyms
MyD88-5, SAMD2, SARM, SARM1, ENSG00000004139

HGNC
HGNC:17074

Entrez Gene
Gene:23098

ENSEMBL
ENSG00000004139
ENSG00000267556

location
chr: 17
start: 26698683
stop: 26728062
strand: +

transcripts
ENST00000457710.3

pathways
Activated TLR4 signalling [NCBI:1269236] [REACTOME:R-HSA-166054] [PUBMED:15276183] [PUBMED:15588429] [PUBMED:15845500] [PUBMED:15596121]
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon [NCBI:1269222] [REACTOME:R-HSA-936964] [PUBMED:15210742] [PUBMED:14679297] [PUBMED:15502848] [PUBMED:17332413]
IKK complex recruitment mediated by RIP1 [NCBI:1269223] [REACTOME:R-HSA-937041] [PUBMED:16603398] [PUBMED:16115877] [PUBMED:14530355]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
MyD88-independent TLR3/TLR4 cascade [NCBI:1269220] [REACTOME:R-HSA-166166] [PUBMED:15276183]
TRAF6 mediated induction of TAK1 complex [NCBI:1269225] [REACTOME:R-HSA-937072] [PUBMED:19112497] [PUBMED:19675569]
TRIF-mediated TLR3/TLR4 signaling [NCBI:1269221] [REACTOME:R-HSA-937061] [PUBMED:15814722] [PUBMED:12855817] [PUBMED:14739303]
Toll Like Receptor 3 (TLR3) Cascade [NCBI:1269219] [REACTOME:R-HSA-168164] [PUBMED:19627256] [PUBMED:15733829] [PUBMED:18202435]
Toll Like Receptor 4 (TLR4) Cascade [NCBI:1269234] [REACTOME:R-HSA-166016]
Toll-Like Receptors Cascades [NCBI:1269204] [REACTOME:R-HSA-168898] [PUBMED:15950447] [PUBMED:12893815] [PUBMED:15976490] [PUBMED:15585605] [PUBMED:14751757]