full name
C-C motif chemokine ligand 5

synonyms
D17S136E, eoCP, RANTES, SCYA5, SIS-delta, SISd, TCP228, CCL5, ENSG00000271503

HGNC
HGNC:10632

Entrez Gene
Gene:6352

ENSEMBL
ENSG00000271503
ENSG00000161570

location
chr: 17
start: 34198495
stop: 34207377
strand: -

OMIM
OMIM:187011: CCL5

transcripts
NM_002985.2
NM_001278736.1

pathways
Chagas disease (American trypanosomiasis) [NCBI:147809] [KEGG:hsa05142] [PUBMED:12377585] [PUBMED:9794425] [PUBMED:1717552] [PUBMED:16238097] [PUBMED:10066513] [PUBMED:12874238] [PUBMED:12036740] [PUBMED:15917295] [PUBMED:12055254] [PUBMED:17651955] [PUBMED:1396957] [PUBMED:16175174] [PUBMED:2194668] [PUBMED:9190942] [PUBMED:12377942] [PUBMED:12427093] [PUBMED:10234174] [PUBMED:16030288] [PUBMED:15223603] [PUBMED:17110955]
Chemokine receptors bind chemokines [NCBI:1269547] [REACTOME:R-HSA-380108] [PUBMED:15578986] [PUBMED:11544102] [PUBMED:10807766]
Chemokine signaling pathway [NCBI:99051] [KEGG:hsa04062] [PUBMED:17371236] [PUBMED:19159344] [PUBMED:17169327] [PUBMED:10852130] [PUBMED:9765254] [PUBMED:15771581] [PUBMED:14607270] [PUBMED:18662984] [PUBMED:12495636] [PUBMED:15803148] [PUBMED:15046611] [PUBMED:12069927] [PUBMED:18711432] [PUBMED:17675482] [PUBMED:16144840] [PUBMED:17496928] [PUBMED:17537990] [PUBMED:11872087] [PUBMED:12051620] [PUBMED:14625285] [PUBMED:8576262] [PUBMED:11244042]
Class A/1 (Rhodopsin-like receptors) [NCBI:1269545] [REACTOME:R-HSA-373076] [PUBMED:16902930]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Cytokine-cytokine receptor interaction [NCBI:83051] [KEGG:hsa04060] [PUBMED:11071910] [PUBMED:12072446] [PUBMED:7791754] [PUBMED:15032600] [PUBMED:12651226] [PUBMED:11252892] [PUBMED:11796220] [PUBMED:11312110] [PUBMED:9862719] [PUBMED:12421671] [PUBMED:12039028] [PUBMED:9759503] [PUBMED:9395284] [PUBMED:11166270] [PUBMED:10714678] [PUBMED:12651221]
Cytosolic DNA-sensing pathway [NCBI:125137] [KEGG:hsa04623] [PUBMED:18573338] [PUBMED:19665965] [PUBMED:19567913] [PUBMED:18280611] [PUBMED:18724932] [PUBMED:19497760] [PUBMED:16286919] [PUBMED:19122387] [PUBMED:19590578] [PUBMED:23258413] [PUBMED:18375758] [PUBMED:19321146] [PUBMED:19362700] [PUBMED:18941233] [PUBMED:19767723]
Epithelial cell signaling in Helicobacter pylori infection [NCBI:83102] [KEGG:hsa05120] [PUBMED:11389469] [PUBMED:15694859] [PUBMED:14700549] [PUBMED:12197905]
G alpha (i) signalling events [NCBI:1269576] [REACTOME:R-HSA-418594] [PUBMED:3113327] [PUBMED:9278091]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Herpes simplex infection [NCBI:377873] [KEGG:hsa05168] [PUBMED:12224518] [PUBMED:17913820] [PUBMED:12844494] [PUBMED:10998601] [PUBMED:15163721] [PUBMED:19694546] [PUBMED:16297150] [PUBMED:14747533] [PUBMED:12826401] [PUBMED:14963113] [PUBMED:15056211] [PUBMED:12797447] [PUBMED:21107701] [PUBMED:10918307] [PUBMED:10696424] [PUBMED:16076403] [PUBMED:10364308] [PUBMED:17222692] [PUBMED:9621021] [PUBMED:12224508] [PUBMED:19879619] [PUBMED:11070032] [PUBMED:9499021] [PUBMED:18596690] [PUBMED:12525427] [PUBMED:12224517] [PUBMED:10196275] [PUBMED:15047834] [PUBMED:18508584] [PUBMED:20036979]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Influenza A [NCBI:217173] [KEGG:hsa05164] [PUBMED:17267598] [PUBMED:18049471] [PUBMED:16882036] [PUBMED:11907320] [PUBMED:17944269] [PUBMED:20629046] [PUBMED:17072332] [PUBMED:18588994] [PUBMED:19864182] [PUBMED:19290913] [PUBMED:19420020] [PUBMED:17213831] [PUBMED:9060654] [PUBMED:19481124] [PUBMED:16494716] [PUBMED:21147034] [PUBMED:18980544] [PUBMED:20020828] [PUBMED:15502848] [PUBMED:19782761]
Interleukin-10 signaling [NCBI:1470924] [REACTOME:R-HSA-6783783] [PUBMED:11244051]
NOD-like receptor signaling pathway [NCBI:122191] [KEGG:hsa04621] [PUBMED:25330206] [PUBMED:21575908] [PUBMED:23846113] [PUBMED:26549800] [PUBMED:16493424] [PUBMED:23124073] [PUBMED:24840700] [PUBMED:27291964] [PUBMED:27012466] [PUBMED:24707857] [PUBMED:19767725] [PUBMED:25879280] [PUBMED:23215645] [PUBMED:22819539] [PUBMED:23702978] [PUBMED:20643110] [PUBMED:25879288] [PUBMED:26655628] [PUBMED:25145756] [PUBMED:24718315] [PUBMED:26482951] [PUBMED:25526305] [PUBMED:26121197] [PUBMED:22430786]
Peptide ligand-binding receptors [NCBI:1269546] [REACTOME:R-HSA-375276] [PUBMED:14576899] [PUBMED:10977869] [PUBMED:16918325] [PUBMED:16847439] [PUBMED:17293890] [PUBMED:15734727] [PUBMED:12895595] [PUBMED:17604107] [PUBMED:14507421] [PUBMED:12432945] [PUBMED:16612131]
Prion diseases [NCBI:101144] [KEGG:hsa05020] [PUBMED:15695097] [PUBMED:18558863] [PUBMED:11592845] [PUBMED:15528202] [PUBMED:17051207] [PUBMED:18245809] [PUBMED:14705136] [PUBMED:10398674] [PUBMED:15890824] [PUBMED:14661267] [PUBMED:15611724] [PUBMED:15342004] [PUBMED:18391177] [PUBMED:17085779] [PUBMED:12850426]
Rheumatoid arthritis [NCBI:200309] [KEGG:hsa05323] [PUBMED:9627005] [PUBMED:17195034] [PUBMED:15059264] [PUBMED:17380158] [PUBMED:20651747] [PUBMED:19455385] [PUBMED:20305562] [PUBMED:20510236] [PUBMED:19184540] [PUBMED:20392226] [PUBMED:17502360] [PUBMED:16313349] [PUBMED:16127012] [PUBMED:15055519] [PUBMED:20036936] [PUBMED:11861618] [PUBMED:19585227] [PUBMED:20193003]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Syndecan-1-mediated signaling events [NCBI:138046] [Pathway Interaction Database:syndecan_1_pathway] [PUBMED:11830493] [PUBMED:8226969] [PUBMED:12904296] [PUBMED:16513763] [PUBMED:7949658] [PUBMED:14637022] [PUBMED:14630925] [PUBMED:1517210] [PUBMED:17267519] [PUBMED:16139226] [PUBMED:16807246] [PUBMED:17579341] [PUBMED:12464176] [PUBMED:11179419] [PUBMED:9660868]
Syndecan-4-mediated signaling events [NCBI:138064] [Pathway Interaction Database:syndecan_4_pathway] [PUBMED:16604063] [PUBMED:8621465] [PUBMED:17485492] [PUBMED:10633082] [PUBMED:14580209] [PUBMED:14670076] [PUBMED:16357320] [PUBMED:11373281] [PUBMED:11805099] [PUBMED:12087088] [PUBMED:16087677] [PUBMED:8589452] [PUBMED:17901052] [PUBMED:12571249] [PUBMED:16310216] [PUBMED:15694365] [PUBMED:17130131] [PUBMED:17879962] [PUBMED:8609172] [PUBMED:12493766] [PUBMED:10640397] [PUBMED:15819887] [PUBMED:10625452] [PUBMED:9582338] [PUBMED:14637022] [PUBMED:12509413] [PUBMED:16141413] [PUBMED:10734086] [PUBMED:10911369]
TNF signaling pathway [NCBI:812256] [KEGG:hsa04668] [PUBMED:20489699] [PUBMED:14532286] [PUBMED:21232019] [PUBMED:11897488] [PUBMED:22296764] [PUBMED:10581243] [PUBMED:23085193] [PUBMED:23531747]
Toll-like receptor signaling pathway [NCBI:83076] [KEGG:hsa04620] [PUBMED:16924467] [PUBMED:17395581] [PUBMED:17637696] [PUBMED:12734364] [PUBMED:17507094] [PUBMED:14698224] [PUBMED:11101877] [PUBMED:16497588] [PUBMED:14751764] [PUBMED:17275323] [PUBMED:17457343] [PUBMED:16932750]
Validated targets of C-MYC transcriptional repression [NCBI:169353] [Pathway Interaction Database:myc_represspathway] [PUBMED:17082179] [PUBMED:11282029] [PUBMED:9869632] [PUBMED:15021909] [PUBMED:16167342] [PUBMED:18056446] [PUBMED:18045875] [PUBMED:1670896] [PUBMED:18393360] [PUBMED:7556187] [PUBMED:11313917] [PUBMED:17471507] [PUBMED:12418961] [PUBMED:9927431] [PUBMED:9924025] [PUBMED:18483244] [PUBMED:14716294] [PUBMED:15506972] [PUBMED:15616584] [PUBMED:12729735] [PUBMED:19219026] [PUBMED:12747840] [PUBMED:2182320] [PUBMED:12545156] [PUBMED:15367674] [PUBMED:11283613] [PUBMED:12384701] [PUBMED:18066065] [PUBMED:18455888] [PUBMED:10920185] [PUBMED:17881732] [PUBMED:20190815] [PUBMED:16352593] [PUBMED:17050536] [PUBMED:11283614] [PUBMED:16391002] [PUBMED:11804592] [PUBMED:7870572] [PUBMED:16940161] [PUBMED:12695333] [PUBMED:17159920] [PUBMED:8972190] [PUBMED:9312026] [PUBMED:17485441] [PUBMED:16288014]