full name
nuclear receptor subfamily 1 group D member 1

synonyms
ear-1, EAR1, hRev, THRA1, THRAL, NR1D1, ENSG00000126368

HGNC
HGNC:7962

Entrez Gene
Gene:9572

ENSEMBL
ENSG00000126368

location
chr: 17
start: 38249037
stop: 38256978
strand: -

transcripts
NM_021724.4

pathways
BMAL1:CLOCK,NPAS2 activates circadian gene expression [NCBI:1269872] [REACTOME:R-HSA-1368108] [PUBMED:12868535] [PUBMED:9616112]
Circadian Clock [NCBI:1269871] [REACTOME:R-HSA-400253] [PUBMED:18775307] [PUBMED:18802415] [PUBMED:18786386] [PUBMED:16987893]
Circadian rhythm [NCBI:83084] [KEGG:hsa04710] [PUBMED:17586087] [PUBMED:12507418] [PUBMED:10864977] [PUBMED:18802415] [PUBMED:17463251] [PUBMED:12150932] [PUBMED:11687489] [PUBMED:12724733] [PUBMED:12015613] [PUBMED:11533719] [PUBMED:12397359] [PUBMED:15917222] [PUBMED:11165242]
Circadian rhythm pathway [NCBI:137978] [Pathway Interaction Database:circadianpathway] [PUBMED:15560782] [PUBMED:11875063] [PUBMED:15798197] [PUBMED:15860628] [PUBMED:14712925] [PUBMED:14750904]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Mitochondrial biogenesis [NCBI:1268839] [REACTOME:R-HSA-1592230] [PUBMED:18430751] [PUBMED:19262508] [PUBMED:22265687] [PUBMED:20533901] [PUBMED:20933024] [PUBMED:21757760] [PUBMED:19575678] [PUBMED:19008463] [PUBMED:21629705] [PUBMED:21543634] [PUBMED:22817841] [PUBMED:20649548] [PUBMED:22146081] [PUBMED:19276888] [PUBMED:19682549] [PUBMED:15744310] [PUBMED:19076454]
NR1D1 (REV-ERBA) represses gene expression [NCBI:1269874] [REACTOME:R-HSA-1368071] [PUBMED:18006707] [PUBMED:20581824] [PUBMED:20414452] [PUBMED:18037887]
Nuclear Receptor transcription pathway [NCBI:1269652] [REACTOME:R-HSA-383280]
Organelle biogenesis and maintenance [NCBI:1268838] [REACTOME:R-HSA-1852241] [PUBMED:8608592] [PUBMED:16103713]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
RORA activates gene expression [NCBI:1269873] [REACTOME:R-HSA-1368082] [PUBMED:7926749]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
Transcriptional activation of mitochondrial biogenesis [NCBI:1268841] [REACTOME:R-HSA-2151201] [PUBMED:22265687] [PUBMED:20933024] [PUBMED:19575678] [PUBMED:22817841] [PUBMED:19682549]