full name
T-box 21

synonyms
T-bet, T-PET, TBET, TBLYM, TBX21, ENSG00000073861

HGNC
HGNC:11599

Entrez Gene
Gene:30009

ENSEMBL
ENSG00000073861

location
chr: 17
start: 45810610
stop: 45823485
strand: +

OMIM
OMIM:604895: TBX21 (Autosomal recessive inheritance)
OMIM:208550: Asthma and nasal polyps
OMIM:208550: {Asthma, aspirin-induced, susceptibility to}

transcripts
NM_013351.1

pathways
Calcineurin-regulated NFAT-dependent transcription in lymphocytes [NCBI:137993] [Pathway Interaction Database:nfat_tfpathway] [PUBMED:11254715] [PUBMED:11356833] [PUBMED:12121669] [PUBMED:10878360] [PUBMED:11786533] [PUBMED:8284217] [PUBMED:10816557] [PUBMED:11956291] [PUBMED:7510691] [PUBMED:9195954] [PUBMED:8240350] [PUBMED:12452838] [PUBMED:8623163] [PUBMED:15834410] [PUBMED:10894164] [PUBMED:10970869] [PUBMED:10755616] [PUBMED:14607827] [PUBMED:12705856] [PUBMED:12086671] [PUBMED:7982959] [PUBMED:9047239] [PUBMED:12374808] [PUBMED:14573767] [PUBMED:12560487] [PUBMED:10570264] [PUBMED:8397339] [PUBMED:12055628] [PUBMED:15308098] [PUBMED:12065418] [PUBMED:7891702] [PUBMED:7749982] [PUBMED:14973438] [PUBMED:8674125] [PUBMED:16873067] [PUBMED:12453415] [PUBMED:8441422] [PUBMED:1737937] [PUBMED:10671476] [PUBMED:8376940] [PUBMED:9545284]
Glucocorticoid receptor regulatory network [NCBI:138014] [Pathway Interaction Database:reg_gr_pathway] [PUBMED:8943293] [PUBMED:1708774] [PUBMED:15826950] [PUBMED:11027313] [PUBMED:12118039] [PUBMED:9388207] [PUBMED:11751894] [PUBMED:12151000] [PUBMED:9765258] [PUBMED:9407028] [PUBMED:19074285] [PUBMED:2838908] [PUBMED:15817653] [PUBMED:9722596] [PUBMED:12917342] [PUBMED:1387550] [PUBMED:10974006] [PUBMED:15790729] [PUBMED:10825196] [PUBMED:10623828] [PUBMED:2169352] [PUBMED:9315653] [PUBMED:7759501] [PUBMED:8290595] [PUBMED:2905764] [PUBMED:12351702] [PUBMED:11080152] [PUBMED:8428574] [PUBMED:9215863] [PUBMED:15459252] [PUBMED:10400612] [PUBMED:9426156] [PUBMED:17440046] [PUBMED:18838540] [PUBMED:2169353] [PUBMED:10820245] [PUBMED:12511605] [PUBMED:2586521] [PUBMED:1740658] [PUBMED:11555652] [PUBMED:11562347] [PUBMED:9482836] [PUBMED:18337589] [PUBMED:10958685] [PUBMED:9388192] [PUBMED:15834420] [PUBMED:15657031] [PUBMED:8878484] [PUBMED:10760263] [PUBMED:12730237] [PUBMED:8702844] [PUBMED:2169351] [PUBMED:17215482] [PUBMED:8898375]
IL12 signaling mediated by STAT4 [NCBI:137936] [Pathway Interaction Database:il12_stat4pathway] [PUBMED:2504877] [PUBMED:7722452] [PUBMED:16365415] [PUBMED:9558063] [PUBMED:8700209] [PUBMED:9325300] [PUBMED:12213961] [PUBMED:10037767] [PUBMED:7737303] [PUBMED:10358173] [PUBMED:16641133] [PUBMED:12372421] [PUBMED:10946290] [PUBMED:11046021] [PUBMED:14660657] [PUBMED:15728489] [PUBMED:10097133] [PUBMED:11207258] [PUBMED:11801649] [PUBMED:11786644] [PUBMED:10229825] [PUBMED:11466347] [PUBMED:12716907] [PUBMED:8700208] [PUBMED:15522880]
IL12-mediated signaling events [NCBI:137922] [Pathway Interaction Database:il12_2pathway] [PUBMED:12874225] [PUBMED:12221108] [PUBMED:16380506] [PUBMED:9768751] [PUBMED:17114419] [PUBMED:10358173] [PUBMED:9890938] [PUBMED:12213961] [PUBMED:11120802] [PUBMED:9202126] [PUBMED:16641133] [PUBMED:10198225] [PUBMED:16763563] [PUBMED:15728489] [PUBMED:8103068] [PUBMED:10903740] [PUBMED:10201984] [PUBMED:7638186] [PUBMED:11894097] [PUBMED:16220539] [PUBMED:10961885] [PUBMED:7594594] [PUBMED:17110450] [PUBMED:9582275] [PUBMED:10320373] [PUBMED:7528775] [PUBMED:11207258] [PUBMED:9038232] [PUBMED:15522880] [PUBMED:11175814] [PUBMED:9531298] [PUBMED:7722452] [PUBMED:8943050] [PUBMED:7553885] [PUBMED:9454765]
IL27-mediated signaling events [NCBI:137929] [Pathway Interaction Database:il27pathway] [PUBMED:11672539] [PUBMED:16365415] [PUBMED:16906167] [PUBMED:15356135] [PUBMED:14657353] [PUBMED:15944269] [PUBMED:14764690] [PUBMED:14614852] [PUBMED:15308705] [PUBMED:15004160] [PUBMED:12734330] [PUBMED:11057672] [PUBMED:15494513] [PUBMED:14614853] [PUBMED:12121660] [PUBMED:16906166] [PUBMED:15749890]
Inflammatory bowel disease (IBD) [NCBI:842771] [KEGG:hsa05321] [PUBMED:17499605] [PUBMED:12006974] [PUBMED:18053739] [PUBMED:20134493] [PUBMED:10898785] [PUBMED:18563156] [PUBMED:23176791] [PUBMED:18200661] [PUBMED:12797537] [PUBMED:21487504] [PUBMED:19381306] [PUBMED:21681604] [PUBMED:19322214] [PUBMED:16493424] [PUBMED:18242222] [PUBMED:12042806] [PUBMED:9759857]
Th1 and Th2 cell differentiation [NCBI:1458885] [KEGG:hsa04658] [PUBMED:15819694] [PUBMED:12171942] [PUBMED:19165228] [PUBMED:23336087] [PUBMED:26044597] [PUBMED:19151746] [PUBMED:19362457] [PUBMED:22044277] [PUBMED:11752608] [PUBMED:23405903] [PUBMED:19375293] [PUBMED:24113868] [PUBMED:19151747] [PUBMED:23624818] [PUBMED:22566933] [PUBMED:11121747] [PUBMED:20969597] [PUBMED:20065998]
Th17 cell differentiation [NCBI:1469482] [KEGG:hsa04659] [PUBMED:23325835] [PUBMED:23036716] [PUBMED:20488727] [PUBMED:21151104] [PUBMED:21084214] [PUBMED:20054607] [PUBMED:22754770] [PUBMED:22640807] [PUBMED:19379825] [PUBMED:22133865] [PUBMED:22324470] [PUBMED:17768419] [PUBMED:18408735] [PUBMED:21776333] [PUBMED:26253381] [PUBMED:16200068] [PUBMED:18362914] [PUBMED:24325586] [PUBMED:19381306] [PUBMED:18166487]