full name
karyopherin subunit alpha 2

synonyms
IPOA1, QIP2, RCH1, SRP1alpha, KPNA2, ENSG00000182481

HGNC
HGNC:6395

Entrez Gene
Gene:3838

ENSEMBL
ENSG00000182481
ENSG00000262472

location
chr: 17
start: 66031848
stop: 66042970
strand: +

transcripts
NM_002266.2

pathways
Antiviral mechanism by IFN-stimulated genes [NCBI:1269316] [REACTOME:R-HSA-1169410]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
DNA Double Strand Break Response [NCBI:1309096] [REACTOME:R-HSA-5693606] [PUBMED:20965415]
DNA Double-Strand Break Repair [NCBI:1309095] [REACTOME:R-HSA-5693532] [PUBMED:12897142] [PUBMED:20965415]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Host Interactions with Influenza Factors [NCBI:1269130] [REACTOME:R-HSA-168253]
ISG15 antiviral mechanism [NCBI:1269317] [REACTOME:R-HSA-1169408] [PUBMED:20153823] [PUBMED:12582176] [PUBMED:16009940] [PUBMED:20946978] [PUBMED:15970528]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Influenza A [NCBI:217173] [KEGG:hsa05164] [PUBMED:17267598] [PUBMED:18049471] [PUBMED:16882036] [PUBMED:11907320] [PUBMED:17944269] [PUBMED:20629046] [PUBMED:17072332] [PUBMED:18588994] [PUBMED:19864182] [PUBMED:19290913] [PUBMED:19420020] [PUBMED:17213831] [PUBMED:9060654] [PUBMED:19481124] [PUBMED:16494716] [PUBMED:21147034] [PUBMED:18980544] [PUBMED:20020828] [PUBMED:15502848] [PUBMED:19782761]
Influenza Infection [NCBI:1269108] [REACTOME:R-HSA-168254]
Interferon Signaling [NCBI:1269311] [REACTOME:R-HSA-913531] [PUBMED:18929502] [PUBMED:15607020] [PUBMED:15864272] [PUBMED:14525967] [PUBMED:19059436]
NS1 Mediated Effects on Host Pathways [NCBI:1269131] [REACTOME:R-HSA-168276]
Regulation of cytoplasmic and nuclear SMAD2/3 signaling [NCBI:138015] [Pathway Interaction Database:smad2_3pathway] [PUBMED:8893010] [PUBMED:12740389] [PUBMED:12193595] [PUBMED:11294908] [PUBMED:10085121] [PUBMED:9620846] [PUBMED:12592392] [PUBMED:14750902] [PUBMED:12917407] [PUBMED:12374795] [PUBMED:16751101] [PUBMED:9346908] [PUBMED:10197981] [PUBMED:12621041] [PUBMED:9214508] [PUBMED:11278302] [PUBMED:17035229] [PUBMED:12191473]
Role of Calcineurin-dependent NFAT signaling in lymphocytes [NCBI:137953] [Pathway Interaction Database:nfat_3pathway] [PUBMED:15743762] [PUBMED:9109491] [PUBMED:1715244] [PUBMED:15121840] [PUBMED:10195903] [PUBMED:10788511] [PUBMED:9630228] [PUBMED:9834092] [PUBMED:9655484] [PUBMED:10933397] [PUBMED:11030334] [PUBMED:8684469] [PUBMED:10861295] [PUBMED:15117942] [PUBMED:12351631] [PUBMED:15902271] [PUBMED:16406492] [PUBMED:10944115] [PUBMED:10611249] [PUBMED:15733859] [PUBMED:15757646] [PUBMED:9768749] [PUBMED:9072970] [PUBMED:12510191] [PUBMED:9585406] [PUBMED:293720] [PUBMED:12925851] [PUBMED:16943420] [PUBMED:11823475] [PUBMED:16141075] [PUBMED:9374467] [PUBMED:9660798] [PUBMED:7528941] [PUBMED:11356833] [PUBMED:10593895] [PUBMED:10866678] [PUBMED:9171236] [PUBMED:12809556] [PUBMED:10652349] [PUBMED:12021260] [PUBMED:16455648]
Sensing of DNA Double Strand Breaks [NCBI:1309097] [REACTOME:R-HSA-5693548] [PUBMED:20965415] [PUBMED:15790808] [PUBMED:12556884] [PUBMED:16141325] [PUBMED:17923702] [PUBMED:12034743] [PUBMED:12427531]
Signaling events mediated by TCPTP [NCBI:169350] [Pathway Interaction Database:tcptp_pathway] [PUBMED:12612081] [PUBMED:18716132] [PUBMED:19171783] [PUBMED:9488479] [PUBMED:15592458] [PUBMED:9261175] [PUBMED:16431927] [PUBMED:15632081] [PUBMED:12359225] [PUBMED:12138178] [PUBMED:7593185] [PUBMED:18840653] [PUBMED:15696169] [PUBMED:18691551] [PUBMED:20484139] [PUBMED:11773439] [PUBMED:16595549] [PUBMED:18948751] [PUBMED:16971512] [PUBMED:12171910] [PUBMED:18819921] [PUBMED:15192089] [PUBMED:17210636] [PUBMED:10488121] [PUBMED:16705167] [PUBMED:14966296] [PUBMED:11909529] [PUBMED:11479308]