full name
mitogen-activated protein kinase kinase 6

synonyms
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3, MAP2K6, ENSG00000108984

HGNC
HGNC:6846

Entrez Gene
Gene:5608

ENSEMBL
ENSG00000108984

location
chr: 17
start: 67410838
stop: 67538470
strand: +

transcripts
NM_002758.3

pathways
Activated TLR4 signalling [NCBI:1269236] [REACTOME:R-HSA-166054] [PUBMED:15276183] [PUBMED:15588429] [PUBMED:15845500] [PUBMED:15596121]
Amyotrophic lateral sclerosis (ALS) [NCBI:83099] [KEGG:hsa05014] [PUBMED:16026864] [PUBMED:16924260] [PUBMED:11513882] [PUBMED:17015226] [PUBMED:16723044] [PUBMED:10970056] [PUBMED:16909020] [PUBMED:12531867] [PUBMED:16713195] [PUBMED:16603792] [PUBMED:11870681] [PUBMED:16050975] [PUBMED:17409386] [PUBMED:11239414] [PUBMED:18519638] [PUBMED:14569202] [PUBMED:12728264] [PUBMED:11715057] [PUBMED:17566607] [PUBMED:17434459] [PUBMED:16909017] [PUBMED:12595144] [PUBMED:15310460] [PUBMED:14739060]
CDC42 signaling events [NCBI:137994] [Pathway Interaction Database:cdc42_pathway] [PUBMED:7629060] [PUBMED:7652575] [PUBMED:8653792] [PUBMED:18448434] [PUBMED:19822663] [PUBMED:19454477] [PUBMED:18662680] [PUBMED:15882626] [PUBMED:11948177] [PUBMED:9860974] [PUBMED:15225553] [PUBMED:8643625] [PUBMED:8107774] [PUBMED:8670801] [PUBMED:8034624] [PUBMED:10934474] [PUBMED:10734320] [PUBMED:17522712] [PUBMED:11525734] [PUBMED:15649357] [PUBMED:10473551] [PUBMED:16157700] [PUBMED:9822598] [PUBMED:15723051] [PUBMED:7600582] [PUBMED:18319301] [PUBMED:9042860] [PUBMED:10613909] [PUBMED:17580073] [PUBMED:12745076] [PUBMED:16253996] [PUBMED:10840034] [PUBMED:10360579] [PUBMED:11907268] [PUBMED:10934475] [PUBMED:10219243] [PUBMED:17038317] [PUBMED:8910292] [PUBMED:9403696] [PUBMED:11285260] [PUBMED:10995437] [PUBMED:9368021] [PUBMED:14970210] [PUBMED:9694656] [PUBMED:14505571] [PUBMED:17115031] [PUBMED:9317150] [PUBMED:14653992] [PUBMED:17081755] [PUBMED:12676083] [PUBMED:18216334] [PUBMED:19826000] [PUBMED:8702968] [PUBMED:11304531] [PUBMED:10973943] [PUBMED:11309380] [PUBMED:18586681] [PUBMED:15479449] [PUBMED:19097998] [PUBMED:16892055] [PUBMED:17244649] [PUBMED:8625410] [PUBMED:8497321] [PUBMED:15485841] [PUBMED:16407834] [PUBMED:11804587] [PUBMED:9867866] [PUBMED:10747870] [PUBMED:7600581] [PUBMED:12610628] [PUBMED:19435802] [PUBMED:15572110] [PUBMED:7592586] [PUBMED:11696321] [PUBMED:10559936]
CDO in myogenesis [NCBI:1270336] [REACTOME:R-HSA-375170] [PUBMED:15923648]
CXCR3-mediated signaling events [NCBI:138011] [Pathway Interaction Database:cxcr3pathway] [PUBMED:15528361] [PUBMED:16210647] [PUBMED:9541591] [PUBMED:16368892] [PUBMED:9660793] [PUBMED:17289675] [PUBMED:16467404] [PUBMED:18291705] [PUBMED:18375741] [PUBMED:15150261] [PUBMED:9625760] [PUBMED:18174362] [PUBMED:11554781] [PUBMED:12750173] [PUBMED:12782716] [PUBMED:11136732] [PUBMED:11739530] [PUBMED:18292502]
Cellular Senescence [NCBI:1270426] [REACTOME:R-HSA-2559583] [PUBMED:21078816] [PUBMED:18711403] [PUBMED:22048312] [PUBMED:19818705] [PUBMED:17662938] [PUBMED:23746838] [PUBMED:9282108] [PUBMED:17667954] [PUBMED:13905658]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Cellular roles of Anthrax toxin [NCBI:138076] [Pathway Interaction Database:anthraxpathway] [PUBMED:12202685] [PUBMED:15031715] [PUBMED:3123387] [PUBMED:11700562] [PUBMED:12700348] [PUBMED:8051159] [PUBMED:15772169] [PUBMED:12867985] [PUBMED:14688124] [PUBMED:15659071] [PUBMED:16473908] [PUBMED:10080100] [PUBMED:9703991] [PUBMED:12724519] [PUBMED:10580119] [PUBMED:11790132] [PUBMED:12468536] [PUBMED:16401723] [PUBMED:15010463] [PUBMED:12724328] [PUBMED:10338520] [PUBMED:9563949] [PUBMED:16429160] [PUBMED:6285339] [PUBMED:3917427] [PUBMED:12488448] [PUBMED:1438214] [PUBMED:9234799] [PUBMED:16254597] [PUBMED:15814721] [PUBMED:16141341] [PUBMED:1644824] [PUBMED:16242117] [PUBMED:16293226]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Epstein-Barr virus infection [NCBI:585562] [KEGG:hsa05169] [PUBMED:1658397] [PUBMED:10683340] [PUBMED:19375142] [PUBMED:12438576] [PUBMED:12910248] [PUBMED:10400785] [PUBMED:16007144] [PUBMED:14576817] [PUBMED:18559925] [PUBMED:16352731] [PUBMED:7895172] [PUBMED:15510157] [PUBMED:21518914] [PUBMED:10891508] [PUBMED:14673102] [PUBMED:17159145] [PUBMED:15542638] [PUBMED:18786993] [PUBMED:16603506] [PUBMED:10644367] [PUBMED:15021898] [PUBMED:10666279] [PUBMED:9565632]
FAS (CD95) signaling pathway [NCBI:138081] [Pathway Interaction Database:faspathway] [PUBMED:9765224] [PUBMED:11717445] [PUBMED:9727491] [PUBMED:11279218] [PUBMED:12110583] [PUBMED:11739735] [PUBMED:8521815] [PUBMED:9184224] [PUBMED:20153221] [PUBMED:9126929] [PUBMED:10200443] [PUBMED:16033886] [PUBMED:8681377] [PUBMED:9880544] [PUBMED:9501089] [PUBMED:10535980] [PUBMED:9727492] [PUBMED:7523573] [PUBMED:11101870] [PUBMED:9321399] [PUBMED:9362518] [PUBMED:12724420] [PUBMED:16498403] [PUBMED:11583996] [PUBMED:15557123] [PUBMED:7536343] [PUBMED:12832037] [PUBMED:9576928] [PUBMED:9228058] [PUBMED:7538908] [PUBMED:18635548] [PUBMED:20038679] [PUBMED:10894163] [PUBMED:12545171] [PUBMED:16619028] [PUBMED:9351817] [PUBMED:9045686] [PUBMED:15289496]
Fc epsilon RI signaling pathway [NCBI:83082] [KEGG:hsa04664] [PUBMED:16470226] [PUBMED:12145654] [PUBMED:11079101] [PUBMED:10586892] [PUBMED:14630197] [PUBMED:12360215] [PUBMED:11449275]
Fluid shear stress and atherosclerosis [NCBI:1474302] [KEGG:hsa05418] [PUBMED:23429585] [PUBMED:21050140] [PUBMED:17599600] [PUBMED:24190880] [PUBMED:22003002] [PUBMED:24876354] [PUBMED:24947523] [PUBMED:23899566] [PUBMED:26597822] [PUBMED:20353494] [PUBMED:22076424] [PUBMED:20538799] [PUBMED:25165867] [PUBMED:20032497] [PUBMED:23084990] [PUBMED:26822720] [PUBMED:24573382] [PUBMED:23555159] [PUBMED:26212910] [PUBMED:21457103] [PUBMED:19151844] [PUBMED:15388638] [PUBMED:16765337] [PUBMED:27027326] [PUBMED:25638487] [PUBMED:21733876]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
GnRH signaling pathway [NCBI:83091] [KEGG:hsa04912] [PUBMED:15080147] [PUBMED:15982836] [PUBMED:14596811] [PUBMED:15613448] [PUBMED:12943720] [PUBMED:10707049] [PUBMED:15350605] [PUBMED:12963732]
IL1-mediated signaling events [NCBI:137944] [Pathway Interaction Database:il1pathway] [PUBMED:10854325] [PUBMED:11287640] [PUBMED:10747026] [PUBMED:11960013] [PUBMED:12150927] [PUBMED:1837145] [PUBMED:17197697] [PUBMED:9374458] [PUBMED:12721283] [PUBMED:8035875] [PUBMED:9261174] [PUBMED:9734363] [PUBMED:11460167] [PUBMED:7878046] [PUBMED:10373529] [PUBMED:2530587] [PUBMED:12538665] [PUBMED:10882101] [PUBMED:9360994] [PUBMED:9062194] [PUBMED:12242293] [PUBMED:8837778] [PUBMED:9430229] [PUBMED:7775431]
IL12-mediated signaling events [NCBI:137922] [Pathway Interaction Database:il12_2pathway] [PUBMED:12874225] [PUBMED:12221108] [PUBMED:16380506] [PUBMED:9768751] [PUBMED:17114419] [PUBMED:10358173] [PUBMED:9890938] [PUBMED:12213961] [PUBMED:11120802] [PUBMED:9202126] [PUBMED:16641133] [PUBMED:10198225] [PUBMED:16763563] [PUBMED:15728489] [PUBMED:8103068] [PUBMED:10903740] [PUBMED:10201984] [PUBMED:7638186] [PUBMED:11894097] [PUBMED:16220539] [PUBMED:10961885] [PUBMED:7594594] [PUBMED:17110450] [PUBMED:9582275] [PUBMED:10320373] [PUBMED:7528775] [PUBMED:11207258] [PUBMED:9038232] [PUBMED:15522880] [PUBMED:11175814] [PUBMED:9531298] [PUBMED:7722452] [PUBMED:8943050] [PUBMED:7553885] [PUBMED:9454765]
IL6-mediated signaling events [NCBI:137932] [Pathway Interaction Database:il6_7pathway] [PUBMED:8559663] [PUBMED:8662591] [PUBMED:11689697] [PUBMED:11727828] [PUBMED:10383440] [PUBMED:10777583] [PUBMED:16774741] [PUBMED:12754507] [PUBMED:9295319] [PUBMED:15722452] [PUBMED:10859312] [PUBMED:9590172] [PUBMED:9880505] [PUBMED:12445202] [PUBMED:8134389] [PUBMED:10409724] [PUBMED:8164674] [PUBMED:8272872] [PUBMED:9794795] [PUBMED:7678052] [PUBMED:8511589] [PUBMED:8668165] [PUBMED:9724754] [PUBMED:8083235] [PUBMED:12754505] [PUBMED:8621622] [PUBMED:16254248] [PUBMED:12361954] [PUBMED:10605021] [PUBMED:9388184] [PUBMED:15935617] [PUBMED:11120832] [PUBMED:7875298] [PUBMED:9973404] [PUBMED:11335711] [PUBMED:9632795] [PUBMED:11468294] [PUBMED:7898939] [PUBMED:8626374] [PUBMED:8670868] [PUBMED:7537214] [PUBMED:15677447] [PUBMED:2261637] [PUBMED:9874564] [PUBMED:12829785] [PUBMED:8537375] [PUBMED:8272873] [PUBMED:7523403] [PUBMED:11251120] [PUBMED:9163525] [PUBMED:3136546] [PUBMED:10727406] [PUBMED:10023775] [PUBMED:12754506] [PUBMED:12456685] [PUBMED:2788034] [PUBMED:10446219] [PUBMED:15572665] [PUBMED:1662392] [PUBMED:15010462] [PUBMED:8140422] [PUBMED:8467812]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Inflammatory mediator regulation of TRP channels [NCBI:948277] [KEGG:hsa04750] [PUBMED:21841075] [PUBMED:15820689] [PUBMED:16776582] [PUBMED:12838328] [PUBMED:17548207] [PUBMED:16319926] [PUBMED:18427980] [PUBMED:20932256] [PUBMED:18615141] [PUBMED:17124270] [PUBMED:17684094] [PUBMED:22470230] [PUBMED:19074743] [PUBMED:23000387] [PUBMED:24099085] [PUBMED:17321113]
Influenza A [NCBI:217173] [KEGG:hsa05164] [PUBMED:17267598] [PUBMED:18049471] [PUBMED:16882036] [PUBMED:11907320] [PUBMED:17944269] [PUBMED:20629046] [PUBMED:17072332] [PUBMED:18588994] [PUBMED:19864182] [PUBMED:19290913] [PUBMED:19420020] [PUBMED:17213831] [PUBMED:9060654] [PUBMED:19481124] [PUBMED:16494716] [PUBMED:21147034] [PUBMED:18980544] [PUBMED:20020828] [PUBMED:15502848] [PUBMED:19782761]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Interleukin-1 signaling [NCBI:1269320] [REACTOME:R-HSA-446652] [PUBMED:19302047] [PUBMED:19022706]
MAP kinase activation in TLR cascade [NCBI:1269211] [REACTOME:R-HSA-450294] [PUBMED:17637696] [PUBMED:11861597] [PUBMED:19196711] [PUBMED:11242034]
MAPK signaling pathway [NCBI:83048] [KEGG:hsa04010] [PUBMED:11749383] [PUBMED:12566928] [PUBMED:12849693] [PUBMED:12676795] [PUBMED:12947395] [PUBMED:14597384] [PUBMED:11369511] [PUBMED:12191611] [PUBMED:12390245]
MyD88 cascade initiated on plasma membrane [NCBI:1269207] [REACTOME:R-HSA-975871] [PUBMED:15728506] [PUBMED:16239509]
MyD88 dependent cascade initiated on endosome [NCBI:1269228] [REACTOME:R-HSA-975155] [PUBMED:20237413] [PUBMED:15276183] [PUBMED:18652679]
MyD88-independent TLR3/TLR4 cascade [NCBI:1269220] [REACTOME:R-HSA-166166] [PUBMED:15276183]
MyD88:Mal cascade initiated on plasma membrane [NCBI:1269237] [REACTOME:R-HSA-166058] [PUBMED:15276183]
Myogenesis [NCBI:1270335] [REACTOME:R-HSA-525793]
NOD1/2 Signaling Pathway [NCBI:1269252] [REACTOME:R-HSA-168638] [PUBMED:18928408] [PUBMED:18585455] [PUBMED:18414735]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways [NCBI:1269251] [REACTOME:R-HSA-168643] [PUBMED:18928408]
Osteoclast differentiation [NCBI:193147] [KEGG:hsa04380] [PUBMED:17633024] [PUBMED:18382763] [PUBMED:18329366] [PUBMED:17869613] [PUBMED:18722561] [PUBMED:15122243] [PUBMED:20703218] [PUBMED:12748652] [PUBMED:12110142] [PUBMED:19585227] [PUBMED:15546140] [PUBMED:16184196] [PUBMED:15817678] [PUBMED:20392226] [PUBMED:16313349] [PUBMED:16313342] [PUBMED:17380158] [PUBMED:18451259]
Oxidative Stress Induced Senescence [NCBI:1270428] [REACTOME:R-HSA-2559580] [PUBMED:17344414] [PUBMED:17332741] [PUBMED:8622688] [PUBMED:7588633] [PUBMED:15563468] [PUBMED:15287722] [PUBMED:11062067] [PUBMED:16337592] [PUBMED:14532106] [PUBMED:17254968] [PUBMED:15866172] [PUBMED:9628874] [PUBMED:12171911] [PUBMED:7816143] [PUBMED:22020331] [PUBMED:11564866] [PUBMED:9162092] [PUBMED:8974401] [PUBMED:19451217] [PUBMED:12808055] [PUBMED:17210787] [PUBMED:8846784] [PUBMED:19462008] [PUBMED:12134156] [PUBMED:8626550] [PUBMED:8774846] [PUBMED:12189133] [PUBMED:9195981] [PUBMED:8622669] [PUBMED:8259215] [PUBMED:19528227] [PUBMED:9564042] [PUBMED:9529249] [PUBMED:16436515] [PUBMED:19451218] [PUBMED:17395714] [PUBMED:9030721] [PUBMED:12435631] [PUBMED:22325352]
PI5P Regulates TP53 Acetylation [NCBI:1457792] [REACTOME:R-HSA-6811555] [PUBMED:10698683] [PUBMED:12859901] [PUBMED:20583997] [PUBMED:16949365] [PUBMED:17940011]
RAC1 signaling pathway [NCBI:169355] [Pathway Interaction Database:rac1_pathway] [PUBMED:19158278] [PUBMED:16702231] [PUBMED:16440308] [PUBMED:14765121] [PUBMED:12453877] [PUBMED:12657629] [PUBMED:9799233] [PUBMED:9694656] [PUBMED:9317150] [PUBMED:14970210] [PUBMED:8305740] [PUBMED:8805275] [PUBMED:17178910] [PUBMED:11060298] [PUBMED:11304531] [PUBMED:11804587] [PUBMED:11470914] [PUBMED:11309380] [PUBMED:17244649] [PUBMED:11021801] [PUBMED:7592586] [PUBMED:15681696] [PUBMED:7744004] [PUBMED:15225553] [PUBMED:10559936] [PUBMED:19917258] [PUBMED:7600581] [PUBMED:19363480] [PUBMED:18423204] [PUBMED:20097736] [PUBMED:19852956] [PUBMED:12181570] [PUBMED:19822663] [PUBMED:7652575] [PUBMED:7629060] [PUBMED:8107774] [PUBMED:16636067] [PUBMED:9042860] [PUBMED:12213441] [PUBMED:10679324] [PUBMED:12682053] [PUBMED:18198193] [PUBMED:16542153] [PUBMED:7600582] [PUBMED:18948007] [PUBMED:18319301] [PUBMED:10559253] [PUBMED:17115053] [PUBMED:10473551] [PUBMED:17682062] [PUBMED:17164293] [PUBMED:15557278] [PUBMED:15677464] [PUBMED:16837009] [PUBMED:12796474] [PUBMED:10559863] [PUBMED:9535855] [PUBMED:8910292] [PUBMED:11432831] [PUBMED:17981134] [PUBMED:16762923] [PUBMED:8798539] [PUBMED:18160398] [PUBMED:16099876] [PUBMED:14681219]
Rap1 signaling pathway [NCBI:868086] [KEGG:hsa04015] [PUBMED:17624944] [PUBMED:12351703] [PUBMED:10579920] [PUBMED:19159611] [PUBMED:18363565] [PUBMED:12765839] [PUBMED:12508104] [PUBMED:11331911] [PUBMED:17182900] [PUBMED:15803158] [PUBMED:19615876] [PUBMED:21402149] [PUBMED:17624948] [PUBMED:17383543] [PUBMED:14607972] [PUBMED:15780587] [PUBMED:19710505]
Regulation of Androgen receptor activity [NCBI:138027] [Pathway Interaction Database:ar_tf_pathway] [PUBMED:15650026] [PUBMED:17045208] [PUBMED:10364196] [PUBMED:16860317] [PUBMED:10611280] [PUBMED:10930412] [PUBMED:1525041] [PUBMED:10779504] [PUBMED:12514133] [PUBMED:1985913] [PUBMED:11931767] [PUBMED:17011549] [PUBMED:15640443] [PUBMED:16322096] [PUBMED:15923603] [PUBMED:14985354] [PUBMED:15743818] [PUBMED:12949936] [PUBMED:11994312] [PUBMED:10567371] [PUBMED:11875111] [PUBMED:15604291] [PUBMED:12890669] [PUBMED:14729952] [PUBMED:9211894] [PUBMED:9162033] [PUBMED:16705743] [PUBMED:16849544] [PUBMED:16923962] [PUBMED:11591700] [PUBMED:16051670] [PUBMED:8643509] [PUBMED:17108144] [PUBMED:16914734] [PUBMED:12682292] [PUBMED:3353726] [PUBMED:11585838] [PUBMED:16282370] [PUBMED:10381882] [PUBMED:15199155] [PUBMED:16455820] [PUBMED:14612401] [PUBMED:10625666] [PUBMED:17679089] [PUBMED:16461774]
Regulation of TP53 Activity [NCBI:1383076] [REACTOME:R-HSA-5633007] [PUBMED:19450511] [PUBMED:20457558] [PUBMED:23825024] [PUBMED:25641576]
Regulation of TP53 Activity through Acetylation [NCBI:1383083] [REACTOME:R-HSA-6804758] [PUBMED:17189186] [PUBMED:22682249] [PUBMED:25799988] [PUBMED:20228809] [PUBMED:16839880] [PUBMED:20660729] [PUBMED:17189187] [PUBMED:23431171] [PUBMED:11099047]
Regulation of p38-alpha and p38-beta [NCBI:137964] [Pathway Interaction Database:p38alphabetapathway] [PUBMED:16461893] [PUBMED:7997261] [PUBMED:16943189] [PUBMED:14585994] [PUBMED:10391943] [PUBMED:14661019] [PUBMED:11359773] [PUBMED:7914033] [PUBMED:8910287] [PUBMED:7744004] [PUBMED:10190877] [PUBMED:7592586] [PUBMED:16849316] [PUBMED:7693711] [PUBMED:11847341] [PUBMED:7839144] [PUBMED:9790884] [PUBMED:7499279] [PUBMED:14592977] [PUBMED:12110590] [PUBMED:14634666] [PUBMED:8107774] [PUBMED:8622669] [PUBMED:8798750] [PUBMED:11278799] [PUBMED:15864310] [PUBMED:16407200]
RhoA signaling pathway [NCBI:169356] [Pathway Interaction Database:rhoa_pathway] [PUBMED:8641286] [PUBMED:16705166] [PUBMED:9510209] [PUBMED:18267089] [PUBMED:15866170] [PUBMED:18303050] [PUBMED:17588931] [PUBMED:18941185] [PUBMED:16164598] [PUBMED:11238375] [PUBMED:18559669] [PUBMED:18025109] [PUBMED:16427251] [PUBMED:11122380] [PUBMED:8632828] [PUBMED:15866889] [PUBMED:9707430] [PUBMED:9456324] [PUBMED:8662509] [PUBMED:12429848] [PUBMED:9294169] [PUBMED:9042860] [PUBMED:9582304] [PUBMED:15170389] [PUBMED:10744700] [PUBMED:10893221] [PUBMED:14681219] [PUBMED:9121475] [PUBMED:8858161] [PUBMED:18309323] [PUBMED:9710582] [PUBMED:9265657] [PUBMED:19625450] [PUBMED:15068801] [PUBMED:11278519] [PUBMED:12732141] [PUBMED:9529607] [PUBMED:12600823] [PUBMED:9697773] [PUBMED:10085083] [PUBMED:12802051] [PUBMED:11018042] [PUBMED:7600583] [PUBMED:9693382] [PUBMED:12899698] [PUBMED:8702756] [PUBMED:10556088] [PUBMED:10037681] [PUBMED:1643657] [PUBMED:12034774] [PUBMED:9670022] [PUBMED:12574166] [PUBMED:12584113] [PUBMED:11877391] [PUBMED:9920882] [PUBMED:8995216] [PUBMED:7929302] [PUBMED:10428028] [PUBMED:15793569] [PUBMED:14595335] [PUBMED:10436006] [PUBMED:9482732] [PUBMED:11342553] [PUBMED:9351440]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Signaling mediated by p38-gamma and p38-delta [NCBI:138043] [Pathway Interaction Database:p38gammadeltapathway] [PUBMED:14697338] [PUBMED:10212242] [PUBMED:9199504] [PUBMED:11500363] [PUBMED:9790884] [PUBMED:9202310] [PUBMED:12761180] [PUBMED:10848581] [PUBMED:11042189] [PUBMED:10438538] [PUBMED:9731215]
TNF signaling pathway [NCBI:812256] [KEGG:hsa04668] [PUBMED:20489699] [PUBMED:14532286] [PUBMED:21232019] [PUBMED:11897488] [PUBMED:22296764] [PUBMED:10581243] [PUBMED:23085193] [PUBMED:23531747]
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation [NCBI:1269229] [REACTOME:R-HSA-975138] [PUBMED:22511786] [PUBMED:18794297]
TRIF-mediated TLR3/TLR4 signaling [NCBI:1269221] [REACTOME:R-HSA-937061] [PUBMED:15814722] [PUBMED:12855817] [PUBMED:14739303]
Toll Like Receptor 10 (TLR10) Cascade [NCBI:1269206] [REACTOME:R-HSA-168142] [PUBMED:15728506] [PUBMED:18332149]
Toll Like Receptor 2 (TLR2) Cascade [NCBI:1269238] [REACTOME:R-HSA-181438] [PUBMED:10820283]
Toll Like Receptor 3 (TLR3) Cascade [NCBI:1269219] [REACTOME:R-HSA-168164] [PUBMED:19627256] [PUBMED:15733829] [PUBMED:18202435]
Toll Like Receptor 4 (TLR4) Cascade [NCBI:1269234] [REACTOME:R-HSA-166016]
Toll Like Receptor 5 (TLR5) Cascade [NCBI:1269226] [REACTOME:R-HSA-168176] [PUBMED:11489966] [PUBMED:11323673]
Toll Like Receptor 7/8 (TLR7/8) Cascade [NCBI:1269227] [REACTOME:R-HSA-168181] [PUBMED:14976262]
Toll Like Receptor 9 (TLR9) Cascade [NCBI:1269233] [REACTOME:R-HSA-168138] [PUBMED:14751759]
Toll Like Receptor TLR1:TLR2 Cascade [NCBI:1269239] [REACTOME:R-HSA-168179] [PUBMED:12975352]
Toll Like Receptor TLR6:TLR2 Cascade [NCBI:1269240] [REACTOME:R-HSA-168188] [PUBMED:14977973]
Toll-Like Receptors Cascades [NCBI:1269204] [REACTOME:R-HSA-168898] [PUBMED:15950447] [PUBMED:12893815] [PUBMED:15976490] [PUBMED:15585605] [PUBMED:14751757]
Toll-like receptor signaling pathway [NCBI:83076] [KEGG:hsa04620] [PUBMED:16924467] [PUBMED:17395581] [PUBMED:17637696] [PUBMED:12734364] [PUBMED:17507094] [PUBMED:14698224] [PUBMED:11101877] [PUBMED:16497588] [PUBMED:14751764] [PUBMED:17275323] [PUBMED:17457343] [PUBMED:16932750]
Toxoplasmosis [NCBI:169642] [KEGG:hsa05145] [PUBMED:18617274] [PUBMED:19400868] [PUBMED:17024357] [PUBMED:19744886] [PUBMED:19891610] [PUBMED:17110955] [PUBMED:12106793] [PUBMED:12580944] [PUBMED:12857995] [PUBMED:10234174] [PUBMED:18327664] [PUBMED:10525166] [PUBMED:18059289] [PUBMED:18775432] [PUBMED:14642303] [PUBMED:15361242] [PUBMED:16339966] [PUBMED:14987366] [PUBMED:15639739]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]
Trk receptor signaling mediated by the MAPK pathway [NCBI:138044] [Pathway Interaction Database:mapktrkpathway] [PUBMED:15632082] [PUBMED:11050086] [PUBMED:9687510] [PUBMED:17003042] [PUBMED:7889942] [PUBMED:11150318] [PUBMED:11331872] [PUBMED:8387505] [PUBMED:1386920] [PUBMED:8394352] [PUBMED:11278445] [PUBMED:15917464] [PUBMED:9560161] [PUBMED:11073940] [PUBMED:12826611] [PUBMED:16157584] [PUBMED:15024033] [PUBMED:9528766] [PUBMED:12011113] [PUBMED:10330161] [PUBMED:11544482] [PUBMED:12367506] [PUBMED:12917366]
Uptake and actions of bacterial toxins [NCBI:1269144] [REACTOME:R-HSA-5339562] [PUBMED:20358680]
Uptake and function of anthrax toxins [NCBI:1269154] [REACTOME:R-HSA-5210891] [PUBMED:17335404] [PUBMED:9563949] [PUBMED:11104681] [PUBMED:6285339] [PUBMED:15353562] [PUBMED:17313374]
activated TAK1 mediates p38 MAPK activation [NCBI:1269213] [REACTOME:R-HSA-450302] [PUBMED:10878576] [PUBMED:8533096] [PUBMED:15837794]
p38 MAPK signaling pathway [NCBI:137943] [Pathway Interaction Database:p38_mkk3_6pathway] [PUBMED:9564042] [PUBMED:12052864] [PUBMED:8663074] [PUBMED:17242196] [PUBMED:10688666] [PUBMED:9774977] [PUBMED:8974401] [PUBMED:9827804] [PUBMED:16129676] [PUBMED:14592977] [PUBMED:17143273] [PUBMED:14634666] [PUBMED:15836773] [PUBMED:14749717] [PUBMED:9305639] [PUBMED:8638164] [PUBMED:10848581] [PUBMED:15864310] [PUBMED:9639556] [PUBMED:17396146] [PUBMED:11460167] [PUBMED:17210579] [PUBMED:9786855]