full name
potassium voltage-gated channel subfamily J member 2

synonyms
ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3, KCNJ2, ENSG00000123700

HGNC
HGNC:6263

Entrez Gene
Gene:3759

ENSEMBL
ENSG00000123700

location
chr: 17
start: 68164757
stop: 68176189
strand: +

OMIM
OMIM:600681: KCNJ2 (Autosomal dominant inheritance)
OMIM:170390: Andersen syndrome
OMIM:613980: Atrial fibrillation, familial, 9
OMIM:609622: Short QT syndrome 3

transcripts
NM_000891.2

pathways
Activation of G protein gated Potassium channels [NCBI:1268826] [REACTOME:R-HSA-1296041] [PUBMED:20655490]
Activation of GABAB receptors [NCBI:1268816] [REACTOME:R-HSA-991365] [PUBMED:20655481]
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:19808464] [PUBMED:26140724] [PUBMED:21357845]
Cholinergic synapse [NCBI:217716] [KEGG:hsa04725] [PUBMED:20060019] [PUBMED:11283752] [PUBMED:15165747] [PUBMED:12893537] [PUBMED:11738031] [PUBMED:21550798] [PUBMED:19712465] [PUBMED:12690458] [PUBMED:12436417] [PUBMED:19378880] [PUBMED:11923408] [PUBMED:20446119]
Classical Kir channels [NCBI:1268829] [REACTOME:R-HSA-1296053] [PUBMED:10599834]
G protein gated Potassium channels [NCBI:1268825] [REACTOME:R-HSA-1296059] [PUBMED:20921230]
GABA B receptor activation [NCBI:1268815] [REACTOME:R-HSA-977444] [PUBMED:20655485]
GABA receptor activation [NCBI:1268813] [REACTOME:R-HSA-977443] [PUBMED:17364682] [PUBMED:20655481] [PUBMED:11283747] [PUBMED:20655485] [PUBMED:15269338]
Gastric acid secretion [NCBI:154409] [KEGG:hsa04971] [PUBMED:17928547] [PUBMED:18474247] [PUBMED:20148676] [PUBMED:15703676] [PUBMED:15579540] [PUBMED:18626068] [PUBMED:20331540] [PUBMED:19889964] [PUBMED:12500969] [PUBMED:16391411] [PUBMED:9307437] [PUBMED:18061403]
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits [NCBI:1268819] [REACTOME:R-HSA-997272] [PUBMED:20655481] [PUBMED:20655490]
Inwardly rectifying K+ channels [NCBI:1268824] [REACTOME:R-HSA-1296065] [PUBMED:20086079] [PUBMED:18087715] [PUBMED:18691387]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell [NCBI:1268786] [REACTOME:R-HSA-112314]
Oxytocin signaling pathway [NCBI:952859] [KEGG:hsa04921] [PUBMED:23356278] [PUBMED:9219843] [PUBMED:20626426] [PUBMED:18555543] [PUBMED:22190926] [PUBMED:21981277] [PUBMED:9575824] [PUBMED:22227279] [PUBMED:19840865] [PUBMED:11861513] [PUBMED:9326674] [PUBMED:12433531] [PUBMED:18655881] [PUBMED:23335873] [PUBMED:22902539] [PUBMED:16156781] [PUBMED:20141572] [PUBMED:14715914] [PUBMED:12009385] [PUBMED:16787565] [PUBMED:16966388]
Phase 4 - resting membrane potential [NCBI:1339116] [REACTOME:R-HSA-5576886] [PUBMED:19808464] [PUBMED:21357845]
Potassium Channels [NCBI:1268821] [REACTOME:R-HSA-1296071] [PUBMED:20813163] [PUBMED:19584315] [PUBMED:1822292] [PUBMED:18446619] [PUBMED:18413784] [PUBMED:20213494] [PUBMED:20086079]
Renin secretion [NCBI:1222951] [KEGG:hsa04924] [PUBMED:24944035] [PUBMED:22733355] [PUBMED:20936939] [PUBMED:12949225] [PUBMED:17360952] [PUBMED:17928544] [PUBMED:19948673] [PUBMED:12388321] [PUBMED:15283749] [PUBMED:22237158] [PUBMED:22258323] [PUBMED:9882634] [PUBMED:20393195] [PUBMED:22124804]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]