full name
potassium voltage-gated channel subfamily J member 2
synonyms
ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3, KCNJ2, ENSG00000123700
HGNC
HGNC:6263
Entrez Gene
Gene:3759
ENSEMBL
ENSG00000123700
location
chr: 17
start: 68164757
stop: 68176189
strand: +
OMIM
OMIM:600681:
KCNJ2
(Autosomal dominant inheritance)
OMIM:170390:
Andersen syndrome
OMIM:613980:
Atrial fibrillation, familial, 9
OMIM:609622:
Short QT syndrome 3
transcripts
NM_000891.2
pathways
Activation of G protein gated Potassium channels
[NCBI:1268826]
[REACTOME:R-HSA-1296041]
[PUBMED:20655490]
Activation of GABAB receptors
[NCBI:1268816]
[REACTOME:R-HSA-991365]
[PUBMED:20655481]
Cardiac conduction
[NCBI:1339115]
[REACTOME:R-HSA-5576891]
[PUBMED:19808464]
[PUBMED:26140724]
[PUBMED:21357845]
Cholinergic synapse
[NCBI:217716]
[KEGG:hsa04725]
[PUBMED:20060019]
[PUBMED:11283752]
[PUBMED:15165747]
[PUBMED:12893537]
[PUBMED:11738031]
[PUBMED:21550798]
[PUBMED:19712465]
[PUBMED:12690458]
[PUBMED:12436417]
[PUBMED:19378880]
[PUBMED:11923408]
[PUBMED:20446119]
Classical Kir channels
[NCBI:1268829]
[REACTOME:R-HSA-1296053]
[PUBMED:10599834]
G protein gated Potassium channels
[NCBI:1268825]
[REACTOME:R-HSA-1296059]
[PUBMED:20921230]
GABA B receptor activation
[NCBI:1268815]
[REACTOME:R-HSA-977444]
[PUBMED:20655485]
GABA receptor activation
[NCBI:1268813]
[REACTOME:R-HSA-977443]
[PUBMED:17364682]
[PUBMED:20655481]
[PUBMED:11283747]
[PUBMED:20655485]
[PUBMED:15269338]
Gastric acid secretion
[NCBI:154409]
[KEGG:hsa04971]
[PUBMED:17928547]
[PUBMED:18474247]
[PUBMED:20148676]
[PUBMED:15703676]
[PUBMED:15579540]
[PUBMED:18626068]
[PUBMED:20331540]
[PUBMED:19889964]
[PUBMED:12500969]
[PUBMED:16391411]
[PUBMED:9307437]
[PUBMED:18061403]
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
[NCBI:1268819]
[REACTOME:R-HSA-997272]
[PUBMED:20655481]
[PUBMED:20655490]
Inwardly rectifying K+ channels
[NCBI:1268824]
[REACTOME:R-HSA-1296065]
[PUBMED:20086079]
[PUBMED:18087715]
[PUBMED:18691387]
Muscle contraction
[NCBI:1269868]
[REACTOME:R-HSA-397014]
Neuronal System
[NCBI:1268763]
[REACTOME:R-HSA-112316]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
[NCBI:1268786]
[REACTOME:R-HSA-112314]
Oxytocin signaling pathway
[NCBI:952859]
[KEGG:hsa04921]
[PUBMED:23356278]
[PUBMED:9219843]
[PUBMED:20626426]
[PUBMED:18555543]
[PUBMED:22190926]
[PUBMED:21981277]
[PUBMED:9575824]
[PUBMED:22227279]
[PUBMED:19840865]
[PUBMED:11861513]
[PUBMED:9326674]
[PUBMED:12433531]
[PUBMED:18655881]
[PUBMED:23335873]
[PUBMED:22902539]
[PUBMED:16156781]
[PUBMED:20141572]
[PUBMED:14715914]
[PUBMED:12009385]
[PUBMED:16787565]
[PUBMED:16966388]
Phase 4 - resting membrane potential
[NCBI:1339116]
[REACTOME:R-HSA-5576886]
[PUBMED:19808464]
[PUBMED:21357845]
Potassium Channels
[NCBI:1268821]
[REACTOME:R-HSA-1296071]
[PUBMED:20813163]
[PUBMED:19584315]
[PUBMED:1822292]
[PUBMED:18446619]
[PUBMED:18413784]
[PUBMED:20213494]
[PUBMED:20086079]
Renin secretion
[NCBI:1222951]
[KEGG:hsa04924]
[PUBMED:24944035]
[PUBMED:22733355]
[PUBMED:20936939]
[PUBMED:12949225]
[PUBMED:17360952]
[PUBMED:17928544]
[PUBMED:19948673]
[PUBMED:12388321]
[PUBMED:15283749]
[PUBMED:22237158]
[PUBMED:22258323]
[PUBMED:9882634]
[PUBMED:20393195]
[PUBMED:22124804]
Transmission across Chemical Synapses
[NCBI:1268766]
[REACTOME:R-HSA-112315]
