full name
acyl-CoA oxidase 1

synonyms
ACOX, PALMCOX, SCOX, ACOX1, ENSG00000161533

HGNC
HGNC:119

Entrez Gene
Gene:51

ENSEMBL
ENSG00000161533

location
chr: 17
start: 73937588
stop: 73975515
strand: -

OMIM
OMIM:609751: ACOX1 (Autosomal recessive inheritance)
OMIM:264470: Peroxisomal acyl-CoA oxidase deficiency

transcripts
NM_004035.6
NM_007292.5
NM_001185039.1

pathways
Beta-oxidation of very long chain fatty acids [NCBI:1270034] [REACTOME:R-HSA-390247] [PUBMED:16756494]
Biosynthesis of unsaturated fatty acids [NCBI:83034] [KEGG:hsa01040] [PUBMED:17719544] [PUBMED:16766224] [PUBMED:11500517] [PUBMED:16564093] [PUBMED:12087109] [PUBMED:12482854]
Fatty acid degradation [NCBI:82935] [KEGG:hsa00071] [PUBMED:869535]
Fatty acid metabolism [NCBI:868084] [KEGG:hsa01212]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
PPAR signaling pathway [NCBI:83042] [KEGG:hsa03320] [PUBMED:15673477] [PUBMED:15828221] [PUBMED:14999402] [PUBMED:15828222] [PUBMED:16601267] [PUBMED:15828220] [PUBMED:10529898] [PUBMED:15828223] [PUBMED:16476485] [PUBMED:11921433] [PUBMED:16511590] [PUBMED:16360030]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
Peroxisomal lipid metabolism [NCBI:1270031] [REACTOME:R-HSA-390918] [PUBMED:16756494]
Peroxisome [NCBI:131226] [KEGG:hsa04146] [PUBMED:17055079] [PUBMED:16631601] [PUBMED:17055078] [PUBMED:17010456]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
alpha-Linolenic acid metabolism [NCBI:82993] [KEGG:hsa00592] [PUBMED:17172287] [PUBMED:15141068] [PUBMED:14522973] [PUBMED:17215350] [PUBMED:16116284] [PUBMED:15670154]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism [NCBI:1270084] [REACTOME:R-HSA-2046104] [PUBMED:10903473] [PUBMED:12324224]
alpha-linolenic acid (ALA) metabolism [NCBI:1270085] [REACTOME:R-HSA-2046106] [PUBMED:8443237] [PUBMED:16828546]
beta-Oxidation [NCBI:413381] [KEGG:hsa_M00087]
cAMP signaling pathway [NCBI:1017634] [KEGG:hsa04024] [PUBMED:10880354] [PUBMED:9204709] [PUBMED:21693691] [PUBMED:24062645] [PUBMED:24450633] [PUBMED:21346730] [PUBMED:24613710] [PUBMED:21744067] [PUBMED:22082266] [PUBMED:16460276] [PUBMED:18176800] [PUBMED:14715909] [PUBMED:7688165] [PUBMED:24281338] [PUBMED:11117527] [PUBMED:16765984] [PUBMED:18323530] [PUBMED:18064650] [PUBMED:21852968] [PUBMED:11493633] [PUBMED:21212391] [PUBMED:15142747] [PUBMED:17077866] [PUBMED:19460777] [PUBMED:19874988] [PUBMED:16571352] [PUBMED:22022314]
fatty acid beta-oxidation (peroxisome) [NCBI:782404] [BIOCYC:HUMAN_PWY66-391] [PUBMED:8387517] [PUBMED:17434787] [PUBMED:16766224] [PUBMED:20558530] [PUBMED:20195903] [PUBMED:11755682] [PUBMED:9230115] [PUBMED:21683154] [PUBMED:17028011] [PUBMED:22864515]