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Genes
IL10
Gene - IL10
full name
interleukin 10
synonyms
CSIF, GVHDS, IL-10, IL10A, TGIF, IL10, ENSG00000136634
HGNC
HGNC:5962
Entrez Gene
Gene:3586
ENSEMBL
ENSG00000136634
location
chr: 1
start: 206940948
stop: 206945839
strand: -
OMIM
OMIM:124092
: IL10
OMIM:614395
: {Graft-versus-host disease, protection against}
OMIM:609423
: {HIV-1, susceptibility to}
OMIM:180300
: {Rheumatoid arthritis, progression of}
transcripts
NM_000572.2
pathways
African trypanosomiasis
[NCBI:194384]
[KEGG:hsa05143]
[PUBMED:9574925]
[PUBMED:12088284]
[PUBMED:19559585]
[PUBMED:20398209]
[PUBMED:17582444]
[PUBMED:19168735]
[PUBMED:19016378]
[PUBMED:11850009]
[PUBMED:16600243]
[PUBMED:19995590]
[PUBMED:19621073]
Allograft rejection
[NCBI:83123]
[KEGG:hsa05330]
[PUBMED:8835634]
[PUBMED:12023610]
[PUBMED:12563298]
[PUBMED:17445565]
[PUBMED:12216939]
[PUBMED:14710779]
[PUBMED:10746853]
[PUBMED:10571983]
[PUBMED:10331992]
[PUBMED:10667806]
Amoebiasis
[NCBI:167324]
[KEGG:hsa05146]
[PUBMED:9832261]
[PUBMED:16380324]
[PUBMED:14700586]
[PUBMED:18725798]
[PUBMED:12142490]
[PUBMED:10637584]
[PUBMED:20145703]
[PUBMED:11378035]
[PUBMED:12160867]
[PUBMED:15813717]
[PUBMED:19207103]
[PUBMED:12660071]
[PUBMED:20303955]
[PUBMED:11352795]
[PUBMED:14502002]
[PUBMED:10756002]
[PUBMED:17702556]
[PUBMED:17576362]
Asthma
[NCBI:83120]
[KEGG:hsa05310]
[PUBMED:11686879]
[PUBMED:17364144]
[PUBMED:10811837]
[PUBMED:11477111]
[PUBMED:18274559]
[PUBMED:11172168]
[PUBMED:18274560]
[PUBMED:10719286]
[PUBMED:12093011]
[PUBMED:17976144]
[PUBMED:17133123]
Autoimmune thyroid disease
[NCBI:83121]
[KEGG:hsa05320]
[PUBMED:15132715]
[PUBMED:12192541]
[PUBMED:17192582]
[PUBMED:9534029]
[PUBMED:11396701]
[PUBMED:11913070]
[PUBMED:15049952]
[PUBMED:11577986]
[PUBMED:15762980]
Chagas disease (American trypanosomiasis)
[NCBI:147809]
[KEGG:hsa05142]
[PUBMED:12377585]
[PUBMED:9794425]
[PUBMED:1717552]
[PUBMED:16238097]
[PUBMED:10066513]
[PUBMED:12874238]
[PUBMED:12036740]
[PUBMED:15917295]
[PUBMED:12055254]
[PUBMED:17651955]
[PUBMED:1396957]
[PUBMED:16175174]
[PUBMED:2194668]
[PUBMED:9190942]
[PUBMED:12377942]
[PUBMED:12427093]
[PUBMED:10234174]
[PUBMED:16030288]
[PUBMED:15223603]
[PUBMED:17110955]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Cytokine-cytokine receptor interaction
[NCBI:83051]
[KEGG:hsa04060]
[PUBMED:11071910]
[PUBMED:12072446]
[PUBMED:7791754]
[PUBMED:15032600]
[PUBMED:12651226]
[PUBMED:11252892]
[PUBMED:11796220]
[PUBMED:11312110]
[PUBMED:9862719]
[PUBMED:12421671]
[PUBMED:12039028]
[PUBMED:9759503]
[PUBMED:9395284]
[PUBMED:11166270]
[PUBMED:10714678]
[PUBMED:12651221]
Epstein-Barr virus infection
[NCBI:585562]
[KEGG:hsa05169]
[PUBMED:1658397]
[PUBMED:10683340]
[PUBMED:19375142]
[PUBMED:12438576]
[PUBMED:12910248]
[PUBMED:10400785]
[PUBMED:16007144]
[PUBMED:14576817]
[PUBMED:18559925]
[PUBMED:16352731]
[PUBMED:7895172]
[PUBMED:15510157]
[PUBMED:21518914]
[PUBMED:10891508]
[PUBMED:14673102]
[PUBMED:17159145]
[PUBMED:15542638]
[PUBMED:18786993]
[PUBMED:16603506]
[PUBMED:10644367]
[PUBMED:15021898]
[PUBMED:10666279]
[PUBMED:9565632]
FoxO signaling pathway
[NCBI:921162]
[KEGG:hsa04068]
[PUBMED:23325358]
[PUBMED:15005655]
[PUBMED:18951090]
[PUBMED:22761423]
[PUBMED:22902436]
[PUBMED:16288288]
[PUBMED:19701188]
[PUBMED:16964248]
[PUBMED:18045156]
[PUBMED:18403263]
[PUBMED:21613825]
[PUBMED:21440011]
[PUBMED:17470511]
[PUBMED:21238503]
[PUBMED:17522590]
[PUBMED:15084259]
[PUBMED:23801966]
[PUBMED:17569704]
[PUBMED:15516968]
IL4-mediated signaling events
[NCBI:137933]
[Pathway Interaction Database:il4_2pathway]
[PUBMED:8602263]
[PUBMED:15199062]
[PUBMED:7705411]
[PUBMED:11160325]
[PUBMED:8557643]
[PUBMED:8134361]
[PUBMED:1948049]
[PUBMED:10843732]
[PUBMED:11034397]
[PUBMED:8624802]
[PUBMED:14557412]
[PUBMED:1997653]
[PUBMED:10586089]
[PUBMED:14634100]
[PUBMED:17541284]
[PUBMED:8124718]
[PUBMED:16210622]
[PUBMED:7822337]
[PUBMED:11572871]
[PUBMED:2147202]
[PUBMED:10228008]
[PUBMED:7675087]
[PUBMED:12574343]
[PUBMED:14603527]
[PUBMED:15659391]
[PUBMED:11160269]
[PUBMED:7760829]
[PUBMED:7973658]
[PUBMED:10072514]
[PUBMED:9013879]
[PUBMED:8624803]
[PUBMED:10490661]
[PUBMED:14978013]
[PUBMED:10364072]
[PUBMED:12459556]
[PUBMED:11714803]
[PUBMED:8602264]
[PUBMED:9811885]
[PUBMED:12776189]
[PUBMED:15728454]
[PUBMED:10601358]
[PUBMED:11739727]
[PUBMED:11160275]
[PUBMED:9852037]
[PUBMED:9670964]
[PUBMED:15004182]
[PUBMED:8266078]
[PUBMED:3144043]
[PUBMED:8992992]
[PUBMED:8089482]
[PUBMED:9651359]
[PUBMED:16810739]
[PUBMED:7499365]
[PUBMED:7721786]
[PUBMED:9065461]
[PUBMED:11241672]
[PUBMED:10950967]
[PUBMED:8810328]
[PUBMED:8624821]
[PUBMED:9110977]
[PUBMED:8609418]
[PUBMED:15187136]
[PUBMED:9414268]
[PUBMED:8916957]
[PUBMED:10201892]
[PUBMED:17200144]
[PUBMED:8458387]
[PUBMED:11544308]
[PUBMED:10657944]
[PUBMED:15153491]
[PUBMED:7544011]
[PUBMED:8266076]
[PUBMED:11801631]
[PUBMED:12044779]
[PUBMED:8621475]
[PUBMED:9697832]
[PUBMED:12242343]
[PUBMED:7694370]
[PUBMED:9380721]
[PUBMED:9541585]
[PUBMED:7807002]
[PUBMED:16537510]
[PUBMED:8258319]
[PUBMED:9799097]
[PUBMED:12023955]
[PUBMED:8085155]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Inflammatory bowel disease (IBD)
[NCBI:842771]
[KEGG:hsa05321]
[PUBMED:17499605]
[PUBMED:12006974]
[PUBMED:18053739]
[PUBMED:20134493]
[PUBMED:10898785]
[PUBMED:18563156]
[PUBMED:23176791]
[PUBMED:18200661]
[PUBMED:12797537]
[PUBMED:21487504]
[PUBMED:19381306]
[PUBMED:21681604]
[PUBMED:19322214]
[PUBMED:16493424]
[PUBMED:18242222]
[PUBMED:12042806]
[PUBMED:9759857]
Interleukin-10 signaling
[NCBI:1470924]
[REACTOME:R-HSA-6783783]
[PUBMED:11244051]
Interleukin-4 and 13 signaling
[NCBI:1470923]
[REACTOME:R-HSA-6785807]
[PUBMED:12704343]
[PUBMED:10358772]
Intestinal immune network for IgA production
[NCBI:128760]
[KEGG:hsa04672]
[PUBMED:18483500]
[PUBMED:18838301]
[PUBMED:15971106]
[PUBMED:18243016]
[PUBMED:19079167]
[PUBMED:18549797]
[PUBMED:19079156]
[PUBMED:17161619]
[PUBMED:17182536]
[PUBMED:12511876]
Jak-STAT signaling pathway
[NCBI:83077]
[KEGG:hsa04630]
[PUBMED:21034406]
[PUBMED:22339650]
[PUBMED:16204702]
[PUBMED:25587654]
[PUBMED:24069565]
[PUBMED:22383755]
[PUBMED:24606160]
[PUBMED:10851053]
[PUBMED:23735217]
[PUBMED:25217450]
[PUBMED:21372217]
Leishmaniasis
[NCBI:144181]
[KEGG:hsa05140]
[PUBMED:11890722]
[PUBMED:7916951]
[PUBMED:10417174]
[PUBMED:11298294]
[PUBMED:10586030]
[PUBMED:15322192]
[PUBMED:15831826]
[PUBMED:11728310]
[PUBMED:15039466]
[PUBMED:10462516]
[PUBMED:10608501]
[PUBMED:15721837]
[PUBMED:15639739]
[PUBMED:14762510]
[PUBMED:18793215]
[PUBMED:7591091]
[PUBMED:12438359]
[PUBMED:18070909]
[PUBMED:17543969]
[PUBMED:15983048]
[PUBMED:16848789]
[PUBMED:10770277]
[PUBMED:9504340]
Malaria
[NCBI:152665]
[KEGG:hsa05144]
[PUBMED:15106591]
[PUBMED:11224682]
[PUBMED:17630968]
[PUBMED:18250459]
[PUBMED:16138104]
[PUBMED:20091081]
[PUBMED:8920859]
[PUBMED:19101208]
[PUBMED:16019257]
[PUBMED:15464448]
[PUBMED:11832955]
[PUBMED:12364790]
[PUBMED:10885986]
[PUBMED:15094163]
[PUBMED:14737184]
[PUBMED:15463497]
[PUBMED:16468982]
[PUBMED:19967139]
Pertussis
[NCBI:218111]
[KEGG:hsa05133]
[PUBMED:20610650]
[PUBMED:12701623]
[PUBMED:15201703]
[PUBMED:18401006]
[PUBMED:20210554]
[PUBMED:16622221]
[PUBMED:17148436]
[PUBMED:21204863]
[PUBMED:20404851]
[PUBMED:10540218]
[PUBMED:16999837]
[PUBMED:16481212]
[PUBMED:16863919]
[PUBMED:16390441]
[PUBMED:21423776]
[PUBMED:17328678]
[PUBMED:12915094]
Regulation of nuclear SMAD2/3 signaling
[NCBI:137963]
[Pathway Interaction Database:smad2_3nuclearpathway]
[PUBMED:15009097]
[PUBMED:11790301]
[PUBMED:11836524]
[PUBMED:10995736]
[PUBMED:11114293]
[PUBMED:10973944]
[PUBMED:10022869]
[PUBMED:11058129]
[PUBMED:9722503]
[PUBMED:12904571]
[PUBMED:14993291]
[PUBMED:11013220]
[PUBMED:15363409]
[PUBMED:9702197]
[PUBMED:12718878]
[PUBMED:11331591]
[PUBMED:12167862]
[PUBMED:14729983]
[PUBMED:9707553]
[PUBMED:10878024]
[PUBMED:9679060]
[PUBMED:10887155]
[PUBMED:10199400]
[PUBMED:12631740]
[PUBMED:11555647]
[PUBMED:15688032]
[PUBMED:12150994]
[PUBMED:12374795]
[PUBMED:9606191]
[PUBMED:9702198]
[PUBMED:10518526]
[PUBMED:10575014]
[PUBMED:10485843]
[PUBMED:11283614]
[PUBMED:10722728]
[PUBMED:10037600]
[PUBMED:15241418]
[PUBMED:14691252]
[PUBMED:10748032]
[PUBMED:12551947]
[PUBMED:14671321]
[PUBMED:11427533]
[PUBMED:11711431]
[PUBMED:10531362]
[PUBMED:11571228]
[PUBMED:10085140]
[PUBMED:17478422]
[PUBMED:15044954]
[PUBMED:10964912]
[PUBMED:11707452]
[PUBMED:11801598]
[PUBMED:17074756]
[PUBMED:12226080]
[PUBMED:10557285]
[PUBMED:10843994]
[PUBMED:15084259]
[PUBMED:10531062]
[PUBMED:16959612]
[PUBMED:9679056]
[PUBMED:10652350]
[PUBMED:9618481]
[PUBMED:11927558]
[PUBMED:9732876]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Staphylococcus aureus infection
[NCBI:172846]
[KEGG:hsa05150]
[PUBMED:18837785]
[PUBMED:16679003]
[PUBMED:18544012]
[PUBMED:15372083]
[PUBMED:19112495]
[PUBMED:16640587]
[PUBMED:15561843]
[PUBMED:16322743]
[PUBMED:16710608]
[PUBMED:16111912]
[PUBMED:11361034]
[PUBMED:12091905]
[PUBMED:16724100]
[PUBMED:16242332]
[PUBMED:17132726]
[PUBMED:20178484]
[PUBMED:16086019]
[PUBMED:12228315]
[PUBMED:19503103]
[PUBMED:14993252]
[PUBMED:18061675]
[PUBMED:17114475]
[PUBMED:17848512]
[PUBMED:17517597]
[PUBMED:20133685]
[PUBMED:18045383]
[PUBMED:16184199]
[PUBMED:17893203]
[PUBMED:20062962]
[PUBMED:15273292]
Systemic lupus erythematosus
[NCBI:83122]
[KEGG:hsa05322]
[PUBMED:12835292]
[PUBMED:12965173]
[PUBMED:16932712]
[PUBMED:10025913]
[PUBMED:15972354]
[PUBMED:17943287]
[PUBMED:10430616]
[PUBMED:18305268]
[PUBMED:15380523]
[PUBMED:8048228]
[PUBMED:15459673]
T cell receptor signaling pathway
[NCBI:83080]
[KEGG:hsa04660]
[PUBMED:17395537]
[PUBMED:15308211]
[PUBMED:15928679]
[PUBMED:14656980]
[PUBMED:17187070]
[PUBMED:15084594]
[PUBMED:16799472]
[PUBMED:12669022]
[PUBMED:15286727]
[PUBMED:15122199]
[PUBMED:19132916]
[PUBMED:15489916]
[PUBMED:11905831]
[PUBMED:12195013]
[PUBMED:15343367]
[PUBMED:12133805]
[PUBMED:14647476]
[PUBMED:15771581]
[PUBMED:15099566]
[PUBMED:14617194]
[PUBMED:19290929]
[PUBMED:15345216]
Toxoplasmosis
[NCBI:169642]
[KEGG:hsa05145]
[PUBMED:18617274]
[PUBMED:19400868]
[PUBMED:17024357]
[PUBMED:19744886]
[PUBMED:19891610]
[PUBMED:17110955]
[PUBMED:12106793]
[PUBMED:12580944]
[PUBMED:12857995]
[PUBMED:10234174]
[PUBMED:18327664]
[PUBMED:10525166]
[PUBMED:18059289]
[PUBMED:18775432]
[PUBMED:14642303]
[PUBMED:15361242]
[PUBMED:16339966]
[PUBMED:14987366]
[PUBMED:15639739]
Tuberculosis
[NCBI:213780]
[KEGG:hsa05152]
[PUBMED:20199890]
[PUBMED:21274449]
[PUBMED:17359235]
[PUBMED:20415982]
[PUBMED:18541216]
[PUBMED:19369951]
[PUBMED:15083155]
[PUBMED:11378475]
[PUBMED:15228522]
[PUBMED:19634703]
[PUBMED:21274433]
[PUBMED:19563525]
[PUBMED:18407066]
[PUBMED:18288961]
[PUBMED:16200082]
[PUBMED:17785780]
[PUBMED:11932234]