Home
About
Citations
Statistics
Download
Login
Home
Genes
RPTOR
Gene - RPTOR
full name
regulatory associated protein of MTOR complex 1
synonyms
KOG1, Mip1, RPTOR, ENSG00000141564
HGNC
HGNC:30287
Entrez Gene
Gene:57521
ENSEMBL
ENSG00000141564
location
chr: 17
start: 78518625
stop: 78940173
strand: +
transcripts
NM_020761.2
NM_001163034.1
pathways
AMPK signaling pathway
[NCBI:989139]
[KEGG:hsa04152]
[PUBMED:22885100]
[PUBMED:18725075]
[PUBMED:22700795]
[PUBMED:19724019]
[PUBMED:19584320]
[PUBMED:16644802]
[PUBMED:20010958]
[PUBMED:16479585]
[PUBMED:19197243]
[PUBMED:23565491]
[PUBMED:20357764]
[PUBMED:16723978]
[PUBMED:16054041]
[PUBMED:19393004]
[PUBMED:23899560]
[PUBMED:17307971]
[PUBMED:15509864]
[PUBMED:23024365]
[PUBMED:23747347]
[PUBMED:19629071]
Autophagy - animal
[NCBI:83058]
[KEGG:hsa04140]
[PUBMED:16200202]
[PUBMED:15325588]
[PUBMED:24343578]
[PUBMED:15978794]
[PUBMED:19802558]
[PUBMED:16099218]
[PUBMED:11099404]
[PUBMED:19653858]
[PUBMED:15325584]
[PUBMED:20034776]
[PUBMED:15928708]
[PUBMED:21801009]
[PUBMED:25948417]
[PUBMED:16125113]
[PUBMED:21187343]
Autophagy - other
[NCBI:1510434]
[KEGG:hsa04136]
[PUBMED:22764279]
[PUBMED:20962583]
[PUBMED:26614870]
[PUBMED:22242963]
[PUBMED:24563201]
[PUBMED:26598298]
[PUBMED:21660427]
Cellular response to heat stress
[NCBI:1270421]
[REACTOME:R-HSA-3371556]
[PUBMED:8455624]
[PUBMED:8441385]
Cellular responses to stress
[NCBI:1270414]
[REACTOME:R-HSA-2262752]
[PUBMED:15709958]
Energy dependent regulation of mTOR by LKB1-AMPK
[NCBI:1269439]
[REACTOME:R-HSA-380972]
[PUBMED:17613433]
[PUBMED:17712357]
[PUBMED:17010524]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
HSF1-dependent transactivation
[NCBI:1270423]
[REACTOME:R-HSA-3371571]
[PUBMED:7623826]
IGF1R signaling cascade
[NCBI:1269618]
[REACTOME:R-HSA-2428924]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
IRS-mediated signalling
[NCBI:1269431]
[REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R
[NCBI:1269620]
[REACTOME:R-HSA-2428928]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:18927274]
[PUBMED:21042815]
[PUBMED:20098959]
Insulin receptor signalling cascade
[NCBI:1269429]
[REACTOME:R-HSA-74751]
[PUBMED:9677303]
[PUBMED:11282018]
Insulin signaling pathway
[NCBI:83090]
[KEGG:hsa04910]
[PUBMED:11742412]
[PUBMED:11343120]
[PUBMED:15733744]
[PUBMED:11282018]
[PUBMED:10196204]
[PUBMED:18291668]
[PUBMED:9609110]
[PUBMED:10567225]
[PUBMED:12791379]
[PUBMED:9748166]
[PUBMED:15624019]
[PUBMED:9445476]
[PUBMED:9346240]
[PUBMED:14635525]
[PUBMED:16288289]
[PUBMED:12867054]
[PUBMED:15229476]
[PUBMED:17344645]
[PUBMED:9609111]
LKB1 signaling events
[NCBI:137957]
[Pathway Interaction Database:lkb1_pathway]
[PUBMED:12429843]
[PUBMED:18339622]
[PUBMED:16912160]
[PUBMED:15454081]
[PUBMED:19513107]
[PUBMED:16959574]
[PUBMED:11741830]
[PUBMED:7706316]
[PUBMED:18063805]
[PUBMED:14614828]
[PUBMED:16306228]
[PUBMED:12489981]
[PUBMED:19386264]
[PUBMED:18439900]
[PUBMED:12805220]
[PUBMED:17959818]
[PUBMED:16396636]
[PUBMED:10542369]
[PUBMED:16308421]
[PUBMED:15016379]
[PUBMED:19622832]
[PUBMED:14511394]
[PUBMED:14676191]
[PUBMED:17482548]
[PUBMED:17991864]
[PUBMED:11445556]
[PUBMED:14651849]
[PUBMED:14517248]
[PUBMED:14985505]
[PUBMED:15261145]
[PUBMED:16817901]
[PUBMED:9108484]
[PUBMED:17573348]
[PUBMED:12973359]
[PUBMED:19369417]
[PUBMED:15705853]
[PUBMED:10642527]
[PUBMED:16627617]
[PUBMED:17482549]
[PUBMED:8631898]
[PUBMED:14976552]
Longevity regulating pathway
[NCBI:1319989]
[KEGG:hsa04211]
[PUBMED:21779512]
[PUBMED:23594965]
[PUBMED:25654554]
[PUBMED:25832544]
[PUBMED:24997879]
[PUBMED:22618766]
[PUBMED:20336132]
[PUBMED:24905167]
[PUBMED:25601466]
[PUBMED:20103737]
[PUBMED:18692468]
[PUBMED:20395504]
[PUBMED:25824609]
[PUBMED:17701476]
[PUBMED:23939249]
[PUBMED:20848587]
[PUBMED:22983298]
[PUBMED:19262508]
[PUBMED:20357764]
[PUBMED:18946478]
[PUBMED:23061800]
Longevity regulating pathway - multiple species
[NCBI:1340713]
[KEGG:hsa04213]
[PUBMED:26682004]
[PUBMED:20098959]
[PUBMED:17684529]
[PUBMED:14534077]
[PUBMED:16304601]
[PUBMED:17701476]
[PUBMED:20395504]
[PUBMED:18373439]
[PUBMED:20336132]
[PUBMED:21909281]
[PUBMED:26525455]
[PUBMED:22094419]
[PUBMED:12610293]
[PUBMED:15768047]
[PUBMED:23615258]
[PUBMED:18946478]
[PUBMED:20097433]
[PUBMED:21841070]
[PUBMED:25153840]
Macroautophagy
[NCBI:1270432]
[REACTOME:R-HSA-1632852]
[PUBMED:24296784]
MicroRNAs in cancer
[NCBI:852705]
[KEGG:hsa05206]
[PUBMED:23075324]
[PUBMED:21742789]
[PUBMED:22351564]
[PUBMED:18817506]
[PUBMED:22345301]
[PUBMED:21402473]
[PUBMED:22926415]
[PUBMED:23165235]
[PUBMED:19630570]
[PUBMED:21565290]
[PUBMED:23091478]
[PUBMED:23462054]
[PUBMED:23316212]
[PUBMED:19773200]
[PUBMED:22035854]
[PUBMED:20221895]
[PUBMED:20345848]
[PUBMED:22580099]
[PUBMED:20128019]
PI3K Cascade
[NCBI:1269432]
[REACTOME:R-HSA-109704]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
PKB-mediated events
[NCBI:1269434]
[REACTOME:R-HSA-109703]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Insulin receptor
[NCBI:1269428]
[REACTOME:R-HSA-74752]
[PUBMED:8276779]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
[NCBI:1269617]
[REACTOME:R-HSA-2404192]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22044904]
[PUBMED:22649417]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
[NCBI:137930]
[Pathway Interaction Database:met_pathway]
[PUBMED:10793146]
[PUBMED:8906793]
[PUBMED:11929826]
[PUBMED:10022866]
[PUBMED:11532961]
[PUBMED:12475979]
[PUBMED:1718989]
[PUBMED:1846706]
[PUBMED:10970810]
[PUBMED:10516287]
[PUBMED:12138161]
[PUBMED:11046147]
[PUBMED:18073207]
[PUBMED:12951049]
[PUBMED:15494312]
[PUBMED:9001234]
[PUBMED:11352916]
[PUBMED:11896055]
[PUBMED:9440692]
[PUBMED:8607979]
[PUBMED:12244132]
[PUBMED:11162460]
[PUBMED:11809798]
[PUBMED:9693375]
[PUBMED:14636584]
[PUBMED:17297451]
[PUBMED:17682062]
[PUBMED:19628037]
[PUBMED:11069926]
[PUBMED:18819921]
[PUBMED:16423831]
[PUBMED:10558875]
[PUBMED:16858414]
[PUBMED:10995442]
[PUBMED:20332103]
[PUBMED:11146548]
[PUBMED:18346875]
[PUBMED:17894413]
[PUBMED:9252406]
[PUBMED:17635922]
[PUBMED:11134526]
[PUBMED:2005882]
[PUBMED:19609305]
[PUBMED:8380735]
[PUBMED:16537482]
[PUBMED:10618718]
[PUBMED:9591773]
[PUBMED:12894582]
[PUBMED:9748249]
[PUBMED:11741535]
[PUBMED:17881575]
[PUBMED:10713050]
[PUBMED:1655790]
[PUBMED:11784715]
[PUBMED:10753869]
[PUBMED:10713700]
[PUBMED:11118451]
[PUBMED:16952352]
[PUBMED:15314156]
[PUBMED:19272169]
[PUBMED:12802068]
[PUBMED:17363898]
[PUBMED:7513258]
[PUBMED:1827664]
[PUBMED:2541345]
[PUBMED:8387483]
[PUBMED:16620780]
[PUBMED:11445578]
[PUBMED:10734310]
[PUBMED:16227611]
[PUBMED:12941962]
[PUBMED:15735664]
[PUBMED:19071214]
[PUBMED:7731718]
[PUBMED:19289496]
[PUBMED:11438654]
[PUBMED:11896612]
[PUBMED:11894096]
[PUBMED:11896575]
[PUBMED:7499247]
[PUBMED:12147692]
[PUBMED:11948414]
[PUBMED:19881549]
[PUBMED:19525225]
[PUBMED:14684163]
[PUBMED:17055484]
[PUBMED:9668053]
[PUBMED:10531383]
[PUBMED:9681449]
[PUBMED:1655405]
[PUBMED:12686592]
[PUBMED:19109251]
[PUBMED:10679787]
[PUBMED:9487126]
[PUBMED:9886295]
[PUBMED:12058075]
[PUBMED:15452053]
[PUBMED:9184210]
[PUBMED:10871282]
[PUBMED:17329361]
[PUBMED:2554238]
TP53 Regulates Metabolic Genes
[NCBI:1269655]
[REACTOME:R-HSA-5628897]
[PUBMED:19822145]
[PUBMED:12453409]
[PUBMED:18344994]
[PUBMED:11545734]
[PUBMED:16839880]
[PUBMED:20399660]
[PUBMED:15105503]
[PUBMED:13298683]
[PUBMED:15665293]
[PUBMED:18198340]
[PUBMED:18692468]
[PUBMED:12203114]
[PUBMED:17409411]
[PUBMED:11959846]
[PUBMED:16728594]
[PUBMED:17486094]
[PUBMED:23484829]
[PUBMED:22682249]
[PUBMED:19696408]
[PUBMED:9926927]
[PUBMED:22864287]
[PUBMED:20378837]
[PUBMED:18391940]
[PUBMED:24366874]
[PUBMED:19439913]
[PUBMED:15059920]
[PUBMED:10716435]
[PUBMED:17540029]
Transcriptional Regulation by TP53
[NCBI:1269654]
[REACTOME:R-HSA-3700989]
[PUBMED:26122615]
[PUBMED:19410540]
mTOR signaling pathway
[NCBI:83059]
[KEGG:hsa04150]
[NCBI:138001]
[Pathway Interaction Database:mtor_4pathway]
[PUBMED:17277771]
[PUBMED:15341740]
[PUBMED:12172553]
[PUBMED:15718470]
[PUBMED:14651849]
[PUBMED:15268862]
[PUBMED:15306821]
[PUBMED:26046644]
[PUBMED:12869586]
[PUBMED:24556838]
[PUBMED:17928295]
[PUBMED:9427642]
[PUBMED:18046414]
[PUBMED:12912918]
[PUBMED:16286006]
[PUBMED:26658722]
[PUBMED:24842496]
[PUBMED:23465396]
[PUBMED:17709744]
[PUBMED:17599906]
[PUBMED:16919458]
[PUBMED:10364159]
[PUBMED:15342917]
[PUBMED:11500364]
[PUBMED:19812304]
[PUBMED:12482958]
[PUBMED:11729323]
[PUBMED:16962653]
[PUBMED:18952604]
[PUBMED:9465032]
[PUBMED:1496022]
[PUBMED:10567431]
[PUBMED:19114562]
[PUBMED:17510057]
[PUBMED:18604198]
[PUBMED:15545625]
[PUBMED:11914378]
[PUBMED:17461779]
[PUBMED:9445476]
[PUBMED:18497260]
[PUBMED:12604610]
[PUBMED:15071500]
[PUBMED:18925875]
[PUBMED:12906785]
[PUBMED:11287630]
[PUBMED:15004009]
[PUBMED:16756488]
[PUBMED:17043309]
[PUBMED:18198340]
[PUBMED:12820960]
[PUBMED:12747827]
[PUBMED:17053147]
[PUBMED:15851026]
[PUBMED:15467718]
[PUBMED:18762023]
[PUBMED:25242279]
[PUBMED:24698685]
[PUBMED:11175345]
[PUBMED:27304501]
[PUBMED:18411301]
[PUBMED:11500365]
[PUBMED:17693255]
[PUBMED:23694989]
[PUBMED:12231510]
[PUBMED:19446321]
[PUBMED:11418588]
[PUBMED:19258318]
[PUBMED:18439900]
[PUBMED:19225151]
[PUBMED:26185979]
[PUBMED:10357815]
[PUBMED:26269525]
[PUBMED:23421405]
[PUBMED:9271440]
[PUBMED:16915281]
[PUBMED:17141160]
[PUBMED:15249583]
[PUBMED:12912989]
[PUBMED:27027448]
[PUBMED:18423201]
[PUBMED:19211835]
[PUBMED:9204908]
[PUBMED:26700098]
[PUBMED:18566587]
[PUBMED:17386266]
mTOR signalling
[NCBI:1269436]
[REACTOME:R-HSA-165159]
[PUBMED:21157483]
mTORC1-mediated signalling
[NCBI:1269438]
[REACTOME:R-HSA-166208]
[PUBMED:23641065]
[PUBMED:22500797]