Logo
full name
myosin light chain 12B

synonyms
MLC-B, MRLC2, MYL12B, ENSG00000118680

HGNC
HGNC:29827

Entrez Gene
Gene:103910

ENSEMBL
ENSG00000118680

location
chr: 18
start: 3262111
stop: 3278282
strand: +

transcripts
NM_033546.3
NM_001144944.1
NM_001144945.1

pathways
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
EPH-Ephrin signaling [NCBI:1270330] [REACTOME:R-HSA-2682334] [PUBMED:18281458] [PUBMED:22120527]
EPHA-mediated growth cone collapse [NCBI:1270331] [REACTOME:R-HSA-3928663] [PUBMED:17300218] [PUBMED:15093606] [PUBMED:15469835] [PUBMED:15848799] [PUBMED:15928710] [PUBMED:11336673]
Focal adhesion [NCBI:83067] [KEGG:hsa04510] [PUBMED:10698680] [PUBMED:15459662] [PUBMED:14756624] [PUBMED:11573199] [PUBMED:12640026] [PUBMED:15179030] [PUBMED:15108811] [PUBMED:15053919] [PUBMED:11082269] [PUBMED:15034601] [PUBMED:12235283] [PUBMED:14519391] [PUBMED:11146675] [PUBMED:11229600] [PUBMED:15688067] [PUBMED:14744429] [PUBMED:11882383]
Leukocyte transendothelial migration [NCBI:83083] [KEGG:hsa04670] [PUBMED:15629883] [PUBMED:10975856] [PUBMED:14976004] [PUBMED:15265790] [PUBMED:15173832] [PUBMED:12540948] [PUBMED:15771581] [PUBMED:15604886] [PUBMED:14977592]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Platelet activation [NCBI:952858] [KEGG:hsa04611] [PUBMED:20002545] [PUBMED:18363565] [PUBMED:18544684] [PUBMED:18174460] [PUBMED:23106920] [PUBMED:18550847] [PUBMED:22119499] [PUBMED:19630797] [PUBMED:19286885] [PUBMED:17158345] [PUBMED:20089227] [PUBMED:22701130] [PUBMED:21071698] [PUBMED:23805129] [PUBMED:16149014] [PUBMED:18641368]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases Activate ROCKs [NCBI:1269510] [REACTOME:R-HSA-5627117] [PUBMED:8662509] [PUBMED:8816443] [PUBMED:11018042] [PUBMED:8702756] [PUBMED:20803696] [PUBMED:8617235] [PUBMED:17151359] [PUBMED:10652353]
RHO GTPases activate CIT [NCBI:1269514] [REACTOME:R-HSA-5625900] [PUBMED:8543060] [PUBMED:23716662] [PUBMED:16202622] [PUBMED:14595335] [PUBMED:22293177] [PUBMED:23444367] [PUBMED:16431929] [PUBMED:9792683] [PUBMED:12802051]
RHO GTPases activate PAKs [NCBI:1269511] [REACTOME:R-HSA-5627123] [PUBMED:7559638] [PUBMED:9535855] [PUBMED:19513348] [PUBMED:16204230] [PUBMED:10470034] [PUBMED:22340718] [PUBMED:11804587] [PUBMED:21098037] [PUBMED:11278486] [PUBMED:8107774] [PUBMED:10975528]
RHO GTPases activate PKNs [NCBI:1269512] [REACTOME:R-HSA-5625740] [PUBMED:21351730] [PUBMED:21749319] [PUBMED:10753910] [PUBMED:18429822] [PUBMED:9175763] [PUBMED:12783890] [PUBMED:14514689] [PUBMED:10924361] [PUBMED:7673228] [PUBMED:10619026] [PUBMED:10467162] [PUBMED:11134534] [PUBMED:9030526] [PUBMED:9988689] [PUBMED:19723632] [PUBMED:24128008] [PUBMED:18006505]
Regulation of actin cytoskeleton [NCBI:83089] [KEGG:hsa04810] [PUBMED:11152757] [PUBMED:11082272] [PUBMED:10574699] [PUBMED:11082269] [PUBMED:14657486] [PUBMED:14744429] [PUBMED:12700767]
Sema4D in semaphorin signaling [NCBI:1270305] [REACTOME:R-HSA-400685] [PUBMED:16314868] [PUBMED:14770294] [PUBMED:15818466]
Sema4D induced cell migration and growth-cone collapse [NCBI:1270307] [REACTOME:R-HSA-416572] [PUBMED:12220504] [PUBMED:18374575] [PUBMED:15210733] [PUBMED:15818466]
Semaphorin interactions [NCBI:1270304] [REACTOME:R-HSA-373755] [PUBMED:12593985] [PUBMED:12471249] [PUBMED:18269210] [PUBMED:16939971] [PUBMED:18374575]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Smooth Muscle Contraction [NCBI:1269870] [REACTOME:R-HSA-445355] [PUBMED:14627618]
Tight junction [NCBI:83071] [KEGG:hsa04530] [PUBMED:25152334] [PUBMED:16650994] [PUBMED:22892070] [PUBMED:18946474] [PUBMED:12042308] [PUBMED:23885123] [PUBMED:16771626] [PUBMED:17182900] [PUBMED:21283798] [PUBMED:25757376] [PUBMED:22928510] [PUBMED:22169974] [PUBMED:25469537] [PUBMED:24651541] [PUBMED:15820555] [PUBMED:17525755] [PUBMED:27353478] [PUBMED:17950242] [PUBMED:18005931] [PUBMED:24548561] [PUBMED:21781017] [PUBMED:20094051] [PUBMED:20134025] [PUBMED:22896795] [PUBMED:18094055] [PUBMED:25483301]