full name
interferon regulatory factor 6

synonyms
LPS, OFC6, PIT, PPS, PPS1, VWS, VWS1, IRF6, ENSG00000117595

HGNC
HGNC:6121

Entrez Gene
Gene:3664

ENSEMBL
ENSG00000117595

location
chr: 1
start: 209958968
stop: 209979520
strand: -

OMIM
OMIM:607199: IRF6 (Autosomal dominant inheritance)
OMIM:119500: Popliteal pterygium syndrome 1
OMIM:119300: van der Woude syndrome
OMIM:608864: {Orofacial cleft 6}

transcripts
NM_001206696.1
NM_006147.3

pathways
Apoptosis [NCBI:83060] [KEGG:hsa04210] [NCBI:198797] [WikiPathways:WP254] [NCBI:1270262] [REACTOME:R-HSA-109581] [PUBMED:20533903] [PUBMED:17914240] [PUBMED:25526085] [PUBMED:22429822] [PUBMED:23070002] [PUBMED:24769728] [PUBMED:15601572] [PUBMED:21914490] [PUBMED:18023214] [PUBMED:12838338] [PUBMED:24278747] [PUBMED:15654015] [PUBMED:21145844] [PUBMED:12949498] [PUBMED:22465226] [PUBMED:14561771] [PUBMED:18238895] [PUBMED:14634621] [PUBMED:14737178] [PUBMED:4561027] [PUBMED:26231733] [PUBMED:9916983] [PUBMED:22075987] [PUBMED:20075940] [PUBMED:19770840] [PUBMED:12505355] [PUBMED:10618704] [PUBMED:12209154] [PUBMED:26615431] [PUBMED:11520933] [PUBMED:16397578] [PUBMED:15322527] [PUBMED:19148180] [PUBMED:23803157] [PUBMED:15719025] [PUBMED:12189384] [PUBMED:18208375] [PUBMED:15218528] [PUBMED:18304445] [PUBMED:9894605] [PUBMED:15725726]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Interferon Signaling [NCBI:1269311] [REACTOME:R-HSA-913531] [PUBMED:18929502] [PUBMED:15607020] [PUBMED:15864272] [PUBMED:14525967] [PUBMED:19059436]
Interferon alpha/beta signaling [NCBI:1269312] [REACTOME:R-HSA-909733] [PUBMED:8621447] [PUBMED:8605876] [PUBMED:17969444] [PUBMED:8702790]
Interferon gamma signaling [NCBI:1269314] [REACTOME:R-HSA-877300] [PUBMED:9462485] [PUBMED:18929502] [PUBMED:9143700] [PUBMED:14525967]