full name
ferrochelatase

synonyms
EPP, FCE, FECH, ENSG00000066926

HGNC
HGNC:3647

Entrez Gene
Gene:2235

ENSEMBL
ENSG00000066926

location
chr: 18
start: 55212073
stop: 55253969
strand: -

OMIM
OMIM:612386: FECH (Autosomal dominant inheritance,Autosomal recessive inheritance)
OMIM:177000: Protoporphyria, erythropoietic, 1

transcripts
NM_000140.3
NM_001012515.2

pathways
HIF-1-alpha transcription factor network [NCBI:138045] [Pathway Interaction Database:hif1_tfpathway] [PUBMED:11707426] [PUBMED:9242677] [PUBMED:9038135] [PUBMED:15310764] [PUBMED:11278891] [PUBMED:8816435] [PUBMED:8663540] [PUBMED:15235127] [PUBMED:12042299] [PUBMED:15312748] [PUBMED:14612449] [PUBMED:11342587] [PUBMED:12615703] [PUBMED:9632793] [PUBMED:12228247] [PUBMED:15044468] [PUBMED:8408001] [PUBMED:9822602] [PUBMED:15252039] [PUBMED:13679920] [PUBMED:11877282] [PUBMED:15235597] [PUBMED:15199161] [PUBMED:15104534] [PUBMED:10594042] [PUBMED:12354771] [PUBMED:10446188] [PUBMED:9436976] [PUBMED:11823643] [PUBMED:12370277] [PUBMED:8955077] [PUBMED:12879018] [PUBMED:14645546] [PUBMED:9486205] [PUBMED:9887100] [PUBMED:8089148] [PUBMED:15466858] [PUBMED:11708773] [PUBMED:15611046] [PUBMED:14742449] [PUBMED:15280364] [PUBMED:12215445] [PUBMED:15611089] [PUBMED:10777486] [PUBMED:9707622] [PUBMED:8917528] [PUBMED:15563275] [PUBMED:12067980] [PUBMED:10353251]
Heme biosynthesis [NCBI:1270187] [REACTOME:R-HSA-189451] [PUBMED:16839620] [PUBMED:10522552]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of porphyrins [NCBI:1270186] [REACTOME:R-HSA-189445]
Porphyrin and chlorophyll metabolism [NCBI:83021] [KEGG:hsa00860] [PUBMED:12195810] [PUBMED:11283349] [PUBMED:10217486] [PUBMED:11007789] [PUBMED:10518530] [PUBMED:12055304] [PUBMED:12196148] [PUBMED:17506685] [PUBMED:16245042] [PUBMED:23922391] [PUBMED:23042036] [PUBMED:9461500]
heme biosynthesis [NCBI:545289] [BIOCYC:HUMAN_PWY-5920] [PUBMED:6769048] [PUBMED:7592564] [PUBMED:3816774] [PUBMED:20506125] [PUBMED:23471474] [PUBMED:9564029] [PUBMED:7592562] [PUBMED:3346226]
heme biosynthesis from uroporphyrinogen-III I [NCBI:142222] [BIOCYC:HUMAN_HEME-BIOSYNTHESIS-II] [PUBMED:20823222]