full name
eukaryotic translation elongation factor 2

synonyms
EEF-2, EF-2, EF2, EEF2, ENSG00000167658

HGNC
HGNC:3214

Entrez Gene
Gene:1938

ENSEMBL
ENSG00000167658

location
chr: 19
start: 3976054
stop: 3985477
strand: -

OMIM
OMIM:130610: EEF2 (Autosomal dominant inheritance)
OMIM:609306: ?Spinocerebellar ataxia 26

transcripts
NM_001961.3

pathways
AMPK signaling pathway [NCBI:989139] [KEGG:hsa04152] [PUBMED:22885100] [PUBMED:18725075] [PUBMED:22700795] [PUBMED:19724019] [PUBMED:19584320] [PUBMED:16644802] [PUBMED:20010958] [PUBMED:16479585] [PUBMED:19197243] [PUBMED:23565491] [PUBMED:20357764] [PUBMED:16723978] [PUBMED:16054041] [PUBMED:19393004] [PUBMED:23899560] [PUBMED:17307971] [PUBMED:15509864] [PUBMED:23024365] [PUBMED:23747347] [PUBMED:19629071]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Eukaryotic Translation Elongation [NCBI:1268690] [REACTOME:R-HSA-156842] [PUBMED:15189156]
Gamma carboxylation, hypusine formation and arylsulfatase activation [NCBI:1268702] [REACTOME:R-HSA-163841]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Oxytocin signaling pathway [NCBI:952859] [KEGG:hsa04921] [PUBMED:23356278] [PUBMED:9219843] [PUBMED:20626426] [PUBMED:18555543] [PUBMED:22190926] [PUBMED:21981277] [PUBMED:9575824] [PUBMED:22227279] [PUBMED:19840865] [PUBMED:11861513] [PUBMED:9326674] [PUBMED:12433531] [PUBMED:18655881] [PUBMED:23335873] [PUBMED:22902539] [PUBMED:16156781] [PUBMED:20141572] [PUBMED:14715914] [PUBMED:12009385] [PUBMED:16787565] [PUBMED:16966388]
Peptide chain elongation [NCBI:1268691] [REACTOME:R-HSA-156902] [PUBMED:12297040]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Protein methylation [NCBI:1470929] [REACTOME:R-HSA-8876725] [PUBMED:25491103]
Synthesis of diphthamide-EEF2 [NCBI:1268708] [REACTOME:R-HSA-5358493] [PUBMED:721806] [PUBMED:23971743] [PUBMED:25352115] [PUBMED:20040] [PUBMED:164179] [PUBMED:23468660] [PUBMED:15485916] [PUBMED:24739148]
Translation [NCBI:1268678] [REACTOME:R-HSA-72766]
Uptake and actions of bacterial toxins [NCBI:1269144] [REACTOME:R-HSA-5339562] [PUBMED:20358680]
Uptake and function of diphtheria toxin [NCBI:1269155] [REACTOME:R-HSA-5336415] [PUBMED:20040] [PUBMED:22069710] [PUBMED:164179]
mTOR signaling pathway [NCBI:83059] [KEGG:hsa04150] [NCBI:138001] [Pathway Interaction Database:mtor_4pathway] [PUBMED:17277771] [PUBMED:15341740] [PUBMED:12172553] [PUBMED:15718470] [PUBMED:14651849] [PUBMED:15268862] [PUBMED:15306821] [PUBMED:26046644] [PUBMED:12869586] [PUBMED:24556838] [PUBMED:17928295] [PUBMED:9427642] [PUBMED:18046414] [PUBMED:12912918] [PUBMED:16286006] [PUBMED:26658722] [PUBMED:24842496] [PUBMED:23465396] [PUBMED:17709744] [PUBMED:17599906] [PUBMED:16919458] [PUBMED:10364159] [PUBMED:15342917] [PUBMED:11500364] [PUBMED:19812304] [PUBMED:12482958] [PUBMED:11729323] [PUBMED:16962653] [PUBMED:18952604] [PUBMED:9465032] [PUBMED:1496022] [PUBMED:10567431] [PUBMED:19114562] [PUBMED:17510057] [PUBMED:18604198] [PUBMED:15545625] [PUBMED:11914378] [PUBMED:17461779] [PUBMED:9445476] [PUBMED:18497260] [PUBMED:12604610] [PUBMED:15071500] [PUBMED:18925875] [PUBMED:12906785] [PUBMED:11287630] [PUBMED:15004009] [PUBMED:16756488] [PUBMED:17043309] [PUBMED:18198340] [PUBMED:12820960] [PUBMED:12747827] [PUBMED:17053147] [PUBMED:15851026] [PUBMED:15467718] [PUBMED:18762023] [PUBMED:25242279] [PUBMED:24698685] [PUBMED:11175345] [PUBMED:27304501] [PUBMED:18411301] [PUBMED:11500365] [PUBMED:17693255] [PUBMED:23694989] [PUBMED:12231510] [PUBMED:19446321] [PUBMED:11418588] [PUBMED:19258318] [PUBMED:18439900] [PUBMED:19225151] [PUBMED:26185979] [PUBMED:10357815] [PUBMED:26269525] [PUBMED:23421405] [PUBMED:9271440] [PUBMED:16915281] [PUBMED:17141160] [PUBMED:15249583] [PUBMED:12912989] [PUBMED:27027448] [PUBMED:18423201] [PUBMED:19211835] [PUBMED:9204908] [PUBMED:26700098] [PUBMED:18566587] [PUBMED:17386266]