Logo
full name
coactivator associated arginine methyltransferase 1

synonyms
PRMT4, CARM1, ENSG00000142453

HGNC
HGNC:23393

Entrez Gene
Gene:10498

ENSEMBL
ENSG00000142453

location
chr: 19
start: 10982253
stop: 11033453
strand: +

transcripts
NM_199141.1

pathways
Activation of gene expression by SREBF (SREBP) [NCBI:1270039] [REACTOME:R-HSA-2426168] [PUBMED:15589694] [PUBMED:9748295] [PUBMED:15457548]
BMAL1:CLOCK,NPAS2 activates circadian gene expression [NCBI:1269872] [REACTOME:R-HSA-1368108] [PUBMED:12868535] [PUBMED:9616112]
Chromatin modifying enzymes [NCBI:1270434] [REACTOME:R-HSA-3247509]
Chromatin organization [NCBI:1270433] [REACTOME:R-HSA-4839726] [PUBMED:21342762] [PUBMED:15598472]
Circadian Clock [NCBI:1269871] [REACTOME:R-HSA-400253] [PUBMED:18775307] [PUBMED:18802415] [PUBMED:18786386] [PUBMED:16987893]
Coregulation of Androgen receptor activity [NCBI:138085] [Pathway Interaction Database:ar_pathway] [PUBMED:16724108] [PUBMED:16027218] [PUBMED:11818503] [PUBMED:17277772] [PUBMED:11719514] [PUBMED:15833840] [PUBMED:16384856] [PUBMED:14645241] [PUBMED:12218053] [PUBMED:11016951] [PUBMED:12621049] [PUBMED:15784617] [PUBMED:16446156] [PUBMED:17110431] [PUBMED:16254014] [PUBMED:17698582] [PUBMED:15131260] [PUBMED:16705743] [PUBMED:11682623] [PUBMED:17192406] [PUBMED:15882980] [PUBMED:10934038] [PUBMED:12165860] [PUBMED:11856738] [PUBMED:16720717] [PUBMED:9710597] [PUBMED:14609956] [PUBMED:17170703] [PUBMED:10383460] [PUBMED:14576337] [PUBMED:12941811] [PUBMED:14612401] [PUBMED:17975004] [PUBMED:12799378] [PUBMED:15790678] [PUBMED:8643607] [PUBMED:11792840] [PUBMED:16603237] [PUBMED:16079795] [PUBMED:16951154] [PUBMED:15166229] [PUBMED:17142810] [PUBMED:12361945] [PUBMED:11439351] [PUBMED:15640154] [PUBMED:17909037] [PUBMED:15539430] [PUBMED:11792709] [PUBMED:11931767] [PUBMED:10344732] [PUBMED:10428808]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Direct p53 effectors [NCBI:137939] [Pathway Interaction Database:p53downstreampathway] [PUBMED:7479001] [PUBMED:19626115] [PUBMED:10692390] [PUBMED:15289308] [PUBMED:14688482] [PUBMED:16301995] [PUBMED:11850816] [PUBMED:12370809] [PUBMED:16260627] [PUBMED:15186775] [PUBMED:15580302] [PUBMED:10748162] [PUBMED:10919640] [PUBMED:19011621] [PUBMED:12438652] [PUBMED:11559530] [PUBMED:11641774] [PUBMED:11971958] [PUBMED:9659898] [PUBMED:9343394] [PUBMED:10716435] [PUBMED:17146433] [PUBMED:17719542] [PUBMED:17938176] [PUBMED:17409421] [PUBMED:11032029] [PUBMED:15781865] [PUBMED:11463392] [PUBMED:9736732] [PUBMED:17268548] [PUBMED:8570655] [PUBMED:18046411] [PUBMED:12944906] [PUBMED:16249378] [PUBMED:15273740] [PUBMED:15598651] [PUBMED:10618379] [PUBMED:15958553] [PUBMED:17189187] [PUBMED:17145718] [PUBMED:11988847] [PUBMED:8119988] [PUBMED:12089322] [PUBMED:16286009] [PUBMED:12890671] [PUBMED:12402042] [PUBMED:10618714] [PUBMED:14730312] [PUBMED:12857899] [PUBMED:14963330] [PUBMED:11278953] [PUBMED:11973653] [PUBMED:12692263] [PUBMED:10984493] [PUBMED:10640990] [PUBMED:11545734] [PUBMED:16151013] [PUBMED:12372430] [PUBMED:16651407] [PUBMED:9891062] [PUBMED:12606722] [PUBMED:12453409] [PUBMED:15377670] [PUBMED:12667443] [PUBMED:17707234] [PUBMED:9920903] [PUBMED:14992722] [PUBMED:15790310] [PUBMED:15831478] [PUBMED:11314010] [PUBMED:10329733] [PUBMED:17264218] [PUBMED:11511362] [PUBMED:11919562] [PUBMED:11814693] [PUBMED:17554199] [PUBMED:18250150] [PUBMED:10518217] [PUBMED:10891498] [PUBMED:10973264] [PUBMED:15077116] [PUBMED:16230375] [PUBMED:18485870] [PUBMED:7796420] [PUBMED:15710382] [PUBMED:17409411] [PUBMED:8319905] [PUBMED:10684646] [PUBMED:7566179] [PUBMED:8887630] [PUBMED:11807984] [PUBMED:9841917] [PUBMED:12654245] [PUBMED:9023107] [PUBMED:15103385] [PUBMED:11684014] [PUBMED:17110336] [PUBMED:11278253] [PUBMED:14576823] [PUBMED:8418500] [PUBMED:11350971] [PUBMED:11840333] [PUBMED:7651818] [PUBMED:7651386] [PUBMED:15378026] [PUBMED:15607964] [PUBMED:11279192] [PUBMED:10777218] [PUBMED:15334053] [PUBMED:12138177] [PUBMED:9619826] [PUBMED:16278683] [PUBMED:17189186] [PUBMED:16140933] [PUBMED:10094469] [PUBMED:9926927] [PUBMED:17719541] [PUBMED:15735003] [PUBMED:12853982] [PUBMED:14707288] [PUBMED:10777207]
Endocrine resistance [NCBI:1404799] [KEGG:hsa01522] [PUBMED:24415977] [PUBMED:23625614] [PUBMED:24841429] [PUBMED:15613444] [PUBMED:23714450] [PUBMED:20960099] [PUBMED:22771991] [PUBMED:19701242] [PUBMED:24289103] [PUBMED:24130921] [PUBMED:23344024] [PUBMED:22015292] [PUBMED:26122181] [PUBMED:26473850] [PUBMED:18804516] [PUBMED:24565562] [PUBMED:26849149] [PUBMED:25907219] [PUBMED:20887199]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Mitochondrial biogenesis [NCBI:1268839] [REACTOME:R-HSA-1592230] [PUBMED:18430751] [PUBMED:19262508] [PUBMED:22265687] [PUBMED:20533901] [PUBMED:20933024] [PUBMED:21757760] [PUBMED:19575678] [PUBMED:19008463] [PUBMED:21629705] [PUBMED:21543634] [PUBMED:22817841] [PUBMED:20649548] [PUBMED:22146081] [PUBMED:19276888] [PUBMED:19682549] [PUBMED:15744310] [PUBMED:19076454]
Organelle biogenesis and maintenance [NCBI:1268838] [REACTOME:R-HSA-1852241] [PUBMED:8608592] [PUBMED:16103713]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
RMTs methylate histone arginines [NCBI:1270439] [REACTOME:R-HSA-3214858] [PUBMED:19150423] [PUBMED:23235912]
RORA activates gene expression [NCBI:1269873] [REACTOME:R-HSA-1368082] [PUBMED:7926749]
Regulation of Androgen receptor activity [NCBI:138027] [Pathway Interaction Database:ar_tf_pathway] [PUBMED:15650026] [PUBMED:17045208] [PUBMED:10364196] [PUBMED:16860317] [PUBMED:10611280] [PUBMED:10930412] [PUBMED:1525041] [PUBMED:10779504] [PUBMED:12514133] [PUBMED:1985913] [PUBMED:11931767] [PUBMED:17011549] [PUBMED:15640443] [PUBMED:16322096] [PUBMED:15923603] [PUBMED:14985354] [PUBMED:15743818] [PUBMED:12949936] [PUBMED:11994312] [PUBMED:10567371] [PUBMED:11875111] [PUBMED:15604291] [PUBMED:12890669] [PUBMED:14729952] [PUBMED:9211894] [PUBMED:9162033] [PUBMED:16705743] [PUBMED:16849544] [PUBMED:16923962] [PUBMED:11591700] [PUBMED:16051670] [PUBMED:8643509] [PUBMED:17108144] [PUBMED:16914734] [PUBMED:12682292] [PUBMED:3353726] [PUBMED:11585838] [PUBMED:16282370] [PUBMED:10381882] [PUBMED:15199155] [PUBMED:16455820] [PUBMED:14612401] [PUBMED:10625666] [PUBMED:17679089] [PUBMED:16461774]
Regulation of cholesterol biosynthesis by SREBP (SREBF) [NCBI:1270038] [REACTOME:R-HSA-1655829] [PUBMED:15457548] [PUBMED:19933148] [PUBMED:18974038]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
TP53 Regulates Transcription of Cell Cycle Genes [NCBI:1383071] [REACTOME:R-HSA-6791312] [PUBMED:12897130] [PUBMED:11896574] [PUBMED:18337750] [PUBMED:24739573] [PUBMED:9184226] [PUBMED:8242751] [PUBMED:11812999] [PUBMED:11574543] [PUBMED:22172947] [PUBMED:17719541] [PUBMED:20460379] [PUBMED:22802529] [PUBMED:9671765] [PUBMED:11814693] [PUBMED:16160013] [PUBMED:23485469] [PUBMED:26122615] [PUBMED:23236473] [PUBMED:22802528] [PUBMED:9712883] [PUBMED:7784094] [PUBMED:20531387] [PUBMED:9780002] [PUBMED:10891498] [PUBMED:22252318] [PUBMED:19276069] [PUBMED:20817677] [PUBMED:14968113] [PUBMED:18431400] [PUBMED:20352051] [PUBMED:12692263] [PUBMED:18719709] [PUBMED:16140933] [PUBMED:7973727] [PUBMED:10524633] [PUBMED:15574328] [PUBMED:24096481] [PUBMED:15186775] [PUBMED:16772293] [PUBMED:8242752] [PUBMED:8944033] [PUBMED:17146433] [PUBMED:9659898]
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest [NCBI:1383073] [REACTOME:R-HSA-6804114] [PUBMED:7784094] [PUBMED:23485469] [PUBMED:15186775] [PUBMED:15574328] [PUBMED:16772293] [PUBMED:10524633] [PUBMED:9659898] [PUBMED:20460379] [PUBMED:11574543] [PUBMED:7973727] [PUBMED:24096481] [PUBMED:17719541]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]
Transcriptional activation of mitochondrial biogenesis [NCBI:1268841] [REACTOME:R-HSA-2151201] [PUBMED:22265687] [PUBMED:20933024] [PUBMED:19575678] [PUBMED:22817841] [PUBMED:19682549]
Transcriptional regulation of white adipocyte differentiation [NCBI:1270345] [REACTOME:R-HSA-381340] [PUBMED:21082419] [PUBMED:17956727] [PUBMED:17475546] [PUBMED:1840554] [PUBMED:17139329] [PUBMED:15860371] [PUBMED:18518822] [PUBMED:10603305] [PUBMED:7531665] [PUBMED:20054179] [PUBMED:7838715] [PUBMED:16054042] [PUBMED:17060461] [PUBMED:17011499] [PUBMED:16380219] [PUBMED:8970730]
YAP1- and WWTR1 (TAZ)-stimulated gene expression [NCBI:1269653] [REACTOME:R-HSA-2032785] [PUBMED:16332960] [PUBMED:20452772]