full name
calcium voltage-gated channel subunit alpha1 A
synonyms
APCA, BI, CACNL1A4, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6, CACNA1A, ENSG00000141837
HGNC
HGNC:1388
Entrez Gene
Gene:773
ENSEMBL
ENSG00000141837
location
chr: 19
start: 13317256
stop: 13617274
strand: -
OMIM
OMIM:601011:
CACNA1A
OMIM:617106:
Epileptic encephalopathy, early infantile, 42
OMIM:108500:
Episodic ataxia, type 2
OMIM:141500:
Migraine, familial hemiplegic, 1
OMIM:141500:
Migraine, familial hemiplegic, 1, with progressive cerebellar ataxia
OMIM:183086:
Spinocerebellar ataxia 6
transcripts
NM_001127222.1
NM_001127221.1
NM_001174080.1
NM_000068.3
NM_023035.2
pathways
Calcium signaling pathway
[NCBI:83050]
[KEGG:hsa04020]
[PUBMED:11080247]
[PUBMED:14572802]
[PUBMED:11413485]
[PUBMED:22129055]
[PUBMED:10508738]
[PUBMED:15000521]
[PUBMED:9235901]
[PUBMED:7861177]
[PUBMED:9149541]
[PUBMED:14517314]
[PUBMED:15111104]
[PUBMED:11698232]
[PUBMED:10331643]
[PUBMED:12838335]
[PUBMED:8125957]
[PUBMED:19172794]
[PUBMED:10997573]
[PUBMED:21338471]
[PUBMED:11299192]
[PUBMED:22002090]
[PUBMED:12972622]
Cholinergic synapse
[NCBI:217716]
[KEGG:hsa04725]
[PUBMED:20060019]
[PUBMED:11283752]
[PUBMED:15165747]
[PUBMED:12893537]
[PUBMED:11738031]
[PUBMED:21550798]
[PUBMED:19712465]
[PUBMED:12690458]
[PUBMED:12436417]
[PUBMED:19378880]
[PUBMED:11923408]
[PUBMED:20446119]
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
[NCBI:1268767]
[REACTOME:R-HSA-112308]
Dopaminergic synapse
[NCBI:469199]
[KEGG:hsa04728]
[PUBMED:20727368]
[PUBMED:10433257]
[PUBMED:17408758]
[PUBMED:15292232]
[PUBMED:9457173]
[PUBMED:17349698]
[PUBMED:15521361]
[PUBMED:18353279]
[PUBMED:21303898]
[PUBMED:19251795]
[PUBMED:15381316]
[PUBMED:15590733]
[PUBMED:20224735]
[PUBMED:19138563]
[PUBMED:12967774]
GABAergic synapse
[NCBI:377263]
[KEGG:hsa04727]
[PUBMED:21555068]
[PUBMED:20655485]
[PUBMED:16932937]
[PUBMED:17499108]
[PUBMED:12086709]
[PUBMED:20655481]
[PUBMED:21376567]
[PUBMED:19374920]
[PUBMED:17499109]
[PUBMED:10780899]
[PUBMED:16787421]
[PUBMED:15210304]
[PUBMED:18382465]
[PUBMED:12888801]
[PUBMED:9364667]
Glutamatergic synapse
[NCBI:213818]
[KEGG:hsa04724]
[PUBMED:10481192]
[PUBMED:11561058]
[PUBMED:18425072]
[PUBMED:17706608]
[PUBMED:20055706]
[PUBMED:19112153]
[PUBMED:17663464]
[PUBMED:19110202]
[PUBMED:19559598]
[PUBMED:9665875]
[PUBMED:11672421]
[PUBMED:18464791]
[PUBMED:12399578]
[PUBMED:14684436]
Integration of energy metabolism
[NCBI:1270101]
[REACTOME:R-HSA-163685]
[PUBMED:15509864]
[PUBMED:12721358]
[PUBMED:12626323]
Long-term depression
[NCBI:83086]
[KEGG:hsa04730]
[PUBMED:9602501]
[PUBMED:9735948]
[PUBMED:14509570]
[PUBMED:11427694]
[PUBMED:12415297]
MAPK signaling pathway
[NCBI:83048]
[KEGG:hsa04010]
[PUBMED:11749383]
[PUBMED:12566928]
[PUBMED:12849693]
[PUBMED:12676795]
[PUBMED:12947395]
[PUBMED:14597384]
[PUBMED:11369511]
[PUBMED:12191611]
[PUBMED:12390245]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Morphine addiction
[NCBI:552665]
[KEGG:hsa05032]
[PUBMED:8785060]
[PUBMED:16581089]
[PUBMED:21872647]
[PUBMED:14625081]
[PUBMED:20962224]
[PUBMED:15661627]
[PUBMED:1346804]
[PUBMED:12859419]
[PUBMED:8096779]
[PUBMED:18349442]
[PUBMED:21930931]
[PUBMED:10066284]
[PUBMED:14969742]
[PUBMED:8987801]
[PUBMED:12217944]
[PUBMED:11750924]
[PUBMED:11152760]
Neuronal System
[NCBI:1268763]
[REACTOME:R-HSA-112316]
Nicotine addiction
[NCBI:583255]
[KEGG:hsa05033]
[PUBMED:19498417]
[PUBMED:15661626]
[PUBMED:12436424]
[PUBMED:19669944]
[PUBMED:19434058]
[PUBMED:19184650]
[PUBMED:15165747]
[PUBMED:12716925]
[PUBMED:18723034]
[PUBMED:18640919]
[PUBMED:11906697]
[PUBMED:14708004]
[PUBMED:17009926]
[PUBMED:14747518]
[PUBMED:20485364]
[PUBMED:16251989]
[PUBMED:20833261]
Regulation of insulin secretion
[NCBI:1270102]
[REACTOME:R-HSA-422356]
[PUBMED:18200017]
[PUBMED:11078440]
[PUBMED:16321791]
[PUBMED:11815463]
[PUBMED:16556766]
Retrograde endocannabinoid signaling
[NCBI:537443]
[KEGG:hsa04723]
[PUBMED:16085309]
[PUBMED:18515270]
[PUBMED:15340387]
[PUBMED:17636069]
[PUBMED:17553427]
[PUBMED:17404373]
[PUBMED:19640475]
[PUBMED:21117095]
[PUBMED:18084639]
[PUBMED:21187849]
[PUBMED:18801434]
[PUBMED:14978245]
[PUBMED:21531987]
[PUBMED:19553483]
[PUBMED:19126760]
[PUBMED:17419048]
[PUBMED:18948642]
[PUBMED:16968947]
Serotonergic synapse
[NCBI:525336]
[KEGG:hsa04726]
[PUBMED:9658404]
[PUBMED:15034221]
[PUBMED:11043573]
[PUBMED:9651340]
[PUBMED:9542727]
[PUBMED:18676031]
[PUBMED:12543273]
[PUBMED:15710402]
[PUBMED:16826372]
[PUBMED:19545642]
[PUBMED:11916537]
[PUBMED:11701344]
[PUBMED:12676358]
[PUBMED:20561690]
[PUBMED:16896947]
Synaptic vesicle cycle
[NCBI:373900]
[KEGG:hsa04721]
[PUBMED:20634814]
[PUBMED:17767192]
[PUBMED:12094216]
[PUBMED:16990140]
[PUBMED:18726177]
[PUBMED:18275379]
[PUBMED:12827282]
[PUBMED:12154365]
[PUBMED:10212473]
[PUBMED:15217342]
[PUBMED:7791897]
[PUBMED:12563290]
Taste transduction
[NCBI:83088]
[KEGG:hsa04742]
[PUBMED:14715493]
[PUBMED:17108952]
[PUBMED:21481196]
[PUBMED:20696704]
[PUBMED:19439032]
[PUBMED:24607224]
[PUBMED:23261954]
[PUBMED:25820328]
[PUBMED:23587289]
[PUBMED:23467090]
[PUBMED:22570381]
[PUBMED:19284629]
[PUBMED:23959882]
[PUBMED:17287577]
[PUBMED:24385952]
Transmission across Chemical Synapses
[NCBI:1268766]
[REACTOME:R-HSA-112315]
Type II diabetes mellitus
[NCBI:83094]
[KEGG:hsa04930]
[PUBMED:12480546]
[PUBMED:15759102]
[PUBMED:9011569]
[PUBMED:11078440]
[PUBMED:11390407]
[PUBMED:15258147]
[PUBMED:15823385]
[PUBMED:11272200]
[PUBMED:11325516]
[PUBMED:15733744]
[PUBMED:9974390]
[PUBMED:7491105]
[PUBMED:15585596]
