full name
glutamyl-prolyl-tRNA synthetase

synonyms
EARS, GLUPRORS, PARS, PIG32, QARS, QPRS, EPRS, ENSG00000136628

HGNC
HGNC:3418

Entrez Gene
Gene:2058

ENSEMBL
ENSG00000136628

location
chr: 1
start: 220141940
stop: 220220000
strand: -

OMIM
OMIM:138295: EPRS
OMIM:617951: Leukodystrophy, hypomyelinating, 15

transcripts
NM_004446.2

pathways
Aminoacyl-tRNA biosynthesis [NCBI:83030] [KEGG:hsa00970] [PUBMED:15314242] [PUBMED:18252769]
Cytosolic tRNA aminoacylation [NCBI:1269710] [REACTOME:R-HSA-379716] [PUBMED:16169847] [PUBMED:14500886] [PUBMED:9878398]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Porphyrin and chlorophyll metabolism [NCBI:83021] [KEGG:hsa00860] [PUBMED:12195810] [PUBMED:11283349] [PUBMED:10217486] [PUBMED:11007789] [PUBMED:10518530] [PUBMED:12055304] [PUBMED:12196148] [PUBMED:17506685] [PUBMED:16245042] [PUBMED:23922391] [PUBMED:23042036] [PUBMED:9461500]
SeMet incorporation into proteins [NCBI:1339155] [REACTOME:R-HSA-2408517] [PUBMED:16661668] [PUBMED:16661782]
Selenoamino acid metabolism [NCBI:1339149] [REACTOME:R-HSA-2408522] [PUBMED:20812787]
tRNA Aminoacylation [NCBI:1269709] [REACTOME:R-HSA-379724] [PUBMED:16125937] [PUBMED:5324173] [PUBMED:18682559] [PUBMED:764868] [PUBMED:1894595] [PUBMED:5324172] [PUBMED:18767960] [PUBMED:182209]
tRNA modification in the nucleus and cytosol [NCBI:1309090] [REACTOME:R-HSA-6782315] [PUBMED:24581449] [PUBMED:24898039] [PUBMED:23139145] [PUBMED:25692999] [PUBMED:24490730] [PUBMED:25780173] [PUBMED:25304425] [PUBMED:24315934]
tRNA processing [NCBI:1309088] [REACTOME:R-HSA-72306] [PUBMED:24315934] [PUBMED:24917879] [PUBMED:7759547] [PUBMED:24898039] [PUBMED:26016801] [PUBMED:24490730] [PUBMED:20810645] [PUBMED:21910628]