Logo
full name
RAB8A, member RAS oncogene family

synonyms
MEL, RAB8, RAB8A, ENSG00000167461

HGNC
HGNC:7007

Entrez Gene
Gene:4218

ENSEMBL
ENSG00000167461

location
chr: 19
start: 16222490
stop: 16244445
strand: +

transcripts
NM_005370.4

pathways
AMPK signaling pathway [NCBI:989139] [KEGG:hsa04152] [PUBMED:22885100] [PUBMED:18725075] [PUBMED:22700795] [PUBMED:19724019] [PUBMED:19584320] [PUBMED:16644802] [PUBMED:20010958] [PUBMED:16479585] [PUBMED:19197243] [PUBMED:23565491] [PUBMED:20357764] [PUBMED:16723978] [PUBMED:16054041] [PUBMED:19393004] [PUBMED:23899560] [PUBMED:17307971] [PUBMED:15509864] [PUBMED:23024365] [PUBMED:23747347] [PUBMED:19629071]
Anchoring of the basal body to the plasma membrane [NCBI:1268847] [REACTOME:R-HSA-5620912] [PUBMED:21816947] [PUBMED:23747070] [PUBMED:19575670] [PUBMED:13978319] [PUBMED:23348840] [PUBMED:25047614] [PUBMED:20819941] [PUBMED:5661997] [PUBMED:21422230] [PUBMED:24469809] [PUBMED:23530209] [PUBMED:21725307] [PUBMED:21680046] [PUBMED:23351793] [PUBMED:21427764] [PUBMED:11676918] [PUBMED:22653444]
Cargo trafficking to the periciliary membrane [NCBI:1268848] [REACTOME:R-HSA-5620920] [PUBMED:20530210] [PUBMED:23150559] [PUBMED:23567335] [PUBMED:17574030] [PUBMED:19081074] [PUBMED:15314642] [PUBMED:22085962] [PUBMED:11384985] [PUBMED:20038682] [PUBMED:11684707] [PUBMED:20399632] [PUBMED:22389062] [PUBMED:9362062] [PUBMED:20603001] [PUBMED:22139371] [PUBMED:22326026] [PUBMED:15998802] [PUBMED:20145001] [PUBMED:12169685]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cilium Assembly [NCBI:1268846] [REACTOME:R-HSA-5617833] [PUBMED:21427764] [PUBMED:23351793] [PUBMED:25040720] [PUBMED:17955020] [PUBMED:22118932] [PUBMED:22653444] [PUBMED:22389062] [PUBMED:20399632] [PUBMED:25047619] [PUBMED:20395968] [PUBMED:23945166] [PUBMED:19575670] [PUBMED:24296415] [PUBMED:20145001] [PUBMED:19602418]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
G2/M Transition [NCBI:1269799] [REACTOME:R-HSA-69275]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Mitotic G2-G2/M phases [NCBI:1269797] [REACTOME:R-HSA-453274]
Organelle biogenesis and maintenance [NCBI:1268838] [REACTOME:R-HSA-1852241] [PUBMED:8608592] [PUBMED:16103713]
Pancreatic secretion [NCBI:169306] [KEGG:hsa04972] [PUBMED:16888148] [PUBMED:9548666] [PUBMED:20224219] [PUBMED:19088252] [PUBMED:15709963] [PUBMED:10078532] [PUBMED:15689674] [PUBMED:10835353] [PUBMED:14660554] [PUBMED:20625287] [PUBMED:16930743] [PUBMED:14637169] [PUBMED:16891880] [PUBMED:18626068] [PUBMED:11087843] [PUBMED:17850212] [PUBMED:17205399]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
RAB GEFs exchange GTP for GDP on RABs [NCBI:1457806] [REACTOME:R-HSA-8876198] [PUBMED:23898197] [PUBMED:16855591] [PUBMED:22694141] [PUBMED:19603039] [PUBMED:7957092] [PUBMED:23303910] [PUBMED:7991565] [PUBMED:25402849] [PUBMED:8631982] [PUBMED:21330364] [PUBMED:8349690] [PUBMED:18532927] [PUBMED:20512138] [PUBMED:8662963] [PUBMED:21250943] [PUBMED:20466531] [PUBMED:25341920] [PUBMED:22251903] [PUBMED:8164745] [PUBMED:1944536] [PUBMED:14574414] [PUBMED:27246931]
RAB geranylgeranylation [NCBI:1470928] [REACTOME:R-HSA-8873719] [PUBMED:16855591] [PUBMED:1944536] [PUBMED:22065758] [PUBMED:8164745] [PUBMED:14574414] [PUBMED:23898197] [PUBMED:22251903] [PUBMED:25341920] [PUBMED:8662963] [PUBMED:7957092] [PUBMED:19603039] [PUBMED:22694141] [PUBMED:7991565] [PUBMED:20937701] [PUBMED:25402849] [PUBMED:18532927] [PUBMED:20512138] [PUBMED:8349690] [PUBMED:8631982]
Regulation of PLK1 Activity at G2/M Transition [NCBI:1269803] [REACTOME:R-HSA-2565942] [PUBMED:12207013] [PUBMED:18615013] [PUBMED:13678582] [PUBMED:18378770] [PUBMED:18566290] [PUBMED:18477460] [PUBMED:22365832]
TBC/RABGAPs [NCBI:1470925] [REACTOME:R-HSA-8854214] [PUBMED:16855591] [PUBMED:22251903]
Tight junction [NCBI:83071] [KEGG:hsa04530] [PUBMED:25152334] [PUBMED:16650994] [PUBMED:22892070] [PUBMED:18946474] [PUBMED:12042308] [PUBMED:23885123] [PUBMED:16771626] [PUBMED:17182900] [PUBMED:21283798] [PUBMED:25757376] [PUBMED:22928510] [PUBMED:22169974] [PUBMED:25469537] [PUBMED:24651541] [PUBMED:15820555] [PUBMED:17525755] [PUBMED:27353478] [PUBMED:17950242] [PUBMED:18005931] [PUBMED:24548561] [PUBMED:21781017] [PUBMED:20094051] [PUBMED:20134025] [PUBMED:22896795] [PUBMED:18094055] [PUBMED:25483301]
Translocation of GLUT4 to the plasma membrane [NCBI:1269896] [REACTOME:R-HSA-1445148] [PUBMED:21306486] [PUBMED:19389739] [PUBMED:18570632] [PUBMED:21216617] [PUBMED:21405107] [PUBMED:20417083]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]
VxPx cargo-targeting to cilium [NCBI:1268849] [REACTOME:R-HSA-5620916] [PUBMED:23945166] [PUBMED:16782012] [PUBMED:16537653] [PUBMED:23567335] [PUBMED:21775626] [PUBMED:19153612]