full name
glucose-6-phosphate isomerase

synonyms
AMF, GNPI, NLK, PGI, PHI, SA-36, SA36, GPI, ENSG00000105220

HGNC
HGNC:4458

Entrez Gene
Gene:2821

ENSEMBL
ENSG00000105220

location
chr: 19
start: 34855645
stop: 34893318
strand: +

OMIM
OMIM:172400: GPI (Autosomal recessive inheritance)
OMIM:613470: Hemolytic anemia, nonspherocytic, due to glucose phosphate isomerase deficiency

transcripts
NM_001184722.1
NM_000175.3

pathways
Amino sugar and nucleotide sugar metabolism [NCBI:82979] [KEGG:hsa00520] [PUBMED:16995900] [PUBMED:15134748] [PUBMED:11479276] [PUBMED:10984043] [PUBMED:16237198] [PUBMED:18199744] [PUBMED:15809294] [PUBMED:8071227] [PUBMED:14450717] [PUBMED:2793832] [PUBMED:16277754] [PUBMED:10931327] [PUBMED:17827295] [PUBMED:15695810] [PUBMED:18304669] [PUBMED:9811644] [PUBMED:11447132] [PUBMED:8444803] [PUBMED:12562791] [PUBMED:17190829] [PUBMED:17085508] [PUBMED:15489439] [PUBMED:16452451]
Carbon metabolism [NCBI:814926] [KEGG:hsa01200]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Gluconeogenesis [NCBI:1269961] [REACTOME:R-HSA-70263] [PUBMED:8379904]
Glucose metabolism [NCBI:1269959] [REACTOME:R-HSA-70326]
Glycolysis [NCBI:1269960] [REACTOME:R-HSA-70171] [PUBMED:16051738]
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [NCBI:413340] [KEGG:hsa_M00001]
Glycolysis / Gluconeogenesis [NCBI:82926] [KEGG:hsa00010]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Pentose phosphate pathway [NCBI:82928] [KEGG:hsa00030] [PUBMED:16788179] [PUBMED:16458304] [PUBMED:16428816] [PUBMED:23279921] [PUBMED:12700258] [PUBMED:20023024]
Pentose phosphate pathway (Pentose phosphate cycle) [NCBI:413343] [KEGG:hsa_M00004]
Starch and sucrose metabolism [NCBI:82974] [KEGG:hsa00500]
TP53 Regulates Metabolic Genes [NCBI:1269655] [REACTOME:R-HSA-5628897] [PUBMED:19822145] [PUBMED:12453409] [PUBMED:18344994] [PUBMED:11545734] [PUBMED:16839880] [PUBMED:20399660] [PUBMED:15105503] [PUBMED:13298683] [PUBMED:15665293] [PUBMED:18198340] [PUBMED:18692468] [PUBMED:12203114] [PUBMED:17409411] [PUBMED:11959846] [PUBMED:16728594] [PUBMED:17486094] [PUBMED:23484829] [PUBMED:22682249] [PUBMED:19696408] [PUBMED:9926927] [PUBMED:22864287] [PUBMED:20378837] [PUBMED:18391940] [PUBMED:24366874] [PUBMED:19439913] [PUBMED:15059920] [PUBMED:10716435] [PUBMED:17540029]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]