full name
free fatty acid receptor 1
synonyms
FFA1R, GPCR40, GPR40, FFAR1, ENSG00000126266
HGNC
HGNC:4498
Entrez Gene
Gene:2864
ENSEMBL
ENSG00000126266
location
chr: 19
start: 35841645
stop: 35844764
strand: +
transcripts
NM_005303.2
pathways
Class A/1 (Rhodopsin-like receptors)
[NCBI:1269545]
[REACTOME:R-HSA-373076]
[PUBMED:16902930]
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
[NCBI:1270106]
[REACTOME:R-HSA-434316]
Free fatty acid receptors
[NCBI:1269569]
[REACTOME:R-HSA-444209]
[PUBMED:15684720]
Free fatty acids regulate insulin secretion
[NCBI:1270105]
[REACTOME:R-HSA-400451]
[PUBMED:18606873]
[PUBMED:17395749]
[PUBMED:17130640]
[PUBMED:18827341]
[PUBMED:15047616]
G alpha (q) signalling events
[NCBI:1269578]
[REACTOME:R-HSA-416476]
[PUBMED:19212139]
GPCR downstream signaling
[NCBI:1269574]
[REACTOME:R-HSA-388396]
[PUBMED:12040175]
GPCR ligand binding
[NCBI:1269544]
[REACTOME:R-HSA-500792]
[PUBMED:15251227]
Gastrin-CREB signalling pathway via PKC and MAPK
[NCBI:1269592]
[REACTOME:R-HSA-881907]
[PUBMED:10413847]
[PUBMED:7491953]
[PUBMED:17698287]
Incretin synthesis, secretion, and inactivation
[NCBI:1268750]
[REACTOME:R-HSA-400508]
[PUBMED:19074620]
[PUBMED:17498508]
[PUBMED:17263764]
Insulin secretion
[NCBI:777534]
[KEGG:hsa04911]
[PUBMED:9715374]
[PUBMED:10605628]
[PUBMED:9914469]
[PUBMED:17306374]
[PUBMED:20055708]
[PUBMED:15655710]
[PUBMED:19817784]
[PUBMED:19074620]
[PUBMED:14693691]
[PUBMED:17084085]
[PUBMED:20551594]
[PUBMED:19036624]
[PUBMED:22970724]
[PUBMED:20225132]
[PUBMED:19817800]
[PUBMED:22974438]
[PUBMED:21934040]
[PUBMED:15271645]
[PUBMED:19660440]
[PUBMED:11522660]
Integration of energy metabolism
[NCBI:1270101]
[REACTOME:R-HSA-163685]
[PUBMED:15509864]
[PUBMED:12721358]
[PUBMED:12626323]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of proteins
[NCBI:1268677]
[REACTOME:R-HSA-392499]
Peptide hormone metabolism
[NCBI:1268746]
[REACTOME:R-HSA-2980736]
[PUBMED:2663045]
[PUBMED:21805235]
Regulation of insulin secretion
[NCBI:1270102]
[REACTOME:R-HSA-422356]
[PUBMED:18200017]
[PUBMED:11078440]
[PUBMED:16321791]
[PUBMED:11815463]
[PUBMED:16556766]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
[NCBI:1268751]
[REACTOME:R-HSA-381771]
[PUBMED:11564718]
[PUBMED:17928588]
[PUBMED:1499644]
[PUBMED:17263764]
[PUBMED:19074620]
[PUBMED:17498508]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
[NCBI:1268752]
[REACTOME:R-HSA-400511]
[PUBMED:19074620]
[PUBMED:17498508]
[PUBMED:17263764]
