full name
free fatty acid receptor 1

synonyms
FFA1R, GPCR40, GPR40, FFAR1, ENSG00000126266

HGNC
HGNC:4498

Entrez Gene
Gene:2864

ENSEMBL
ENSG00000126266

location
chr: 19
start: 35841645
stop: 35844764
strand: +

transcripts
NM_005303.2

pathways
Class A/1 (Rhodopsin-like receptors) [NCBI:1269545] [REACTOME:R-HSA-373076] [PUBMED:16902930]
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion [NCBI:1270106] [REACTOME:R-HSA-434316]
Free fatty acid receptors [NCBI:1269569] [REACTOME:R-HSA-444209] [PUBMED:15684720]
Free fatty acids regulate insulin secretion [NCBI:1270105] [REACTOME:R-HSA-400451] [PUBMED:18606873] [PUBMED:17395749] [PUBMED:17130640] [PUBMED:18827341] [PUBMED:15047616]
G alpha (q) signalling events [NCBI:1269578] [REACTOME:R-HSA-416476] [PUBMED:19212139]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
Incretin synthesis, secretion, and inactivation [NCBI:1268750] [REACTOME:R-HSA-400508] [PUBMED:19074620] [PUBMED:17498508] [PUBMED:17263764]
Insulin secretion [NCBI:777534] [KEGG:hsa04911] [PUBMED:9715374] [PUBMED:10605628] [PUBMED:9914469] [PUBMED:17306374] [PUBMED:20055708] [PUBMED:15655710] [PUBMED:19817784] [PUBMED:19074620] [PUBMED:14693691] [PUBMED:17084085] [PUBMED:20551594] [PUBMED:19036624] [PUBMED:22970724] [PUBMED:20225132] [PUBMED:19817800] [PUBMED:22974438] [PUBMED:21934040] [PUBMED:15271645] [PUBMED:19660440] [PUBMED:11522660]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Peptide hormone metabolism [NCBI:1268746] [REACTOME:R-HSA-2980736] [PUBMED:2663045] [PUBMED:21805235]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:11078440] [PUBMED:16321791] [PUBMED:11815463] [PUBMED:16556766]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) [NCBI:1268751] [REACTOME:R-HSA-381771] [PUBMED:11564718] [PUBMED:17928588] [PUBMED:1499644] [PUBMED:17263764] [PUBMED:19074620] [PUBMED:17498508]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) [NCBI:1268752] [REACTOME:R-HSA-400511] [PUBMED:19074620] [PUBMED:17498508] [PUBMED:17263764]