full name
egl-9 family hypoxia inducible factor 2

synonyms
EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, EGLN2, ENSG00000269858

HGNC
HGNC:14660

Entrez Gene
Gene:112398

ENSEMBL
ENSG00000269858

location
chr: 19
start: 41305048
stop: 41314346
strand: +

transcripts
NM_080732.3
NM_053046.3

pathways
Cellular response to hypoxia [NCBI:1270415] [REACTOME:R-HSA-2262749] [PUBMED:15304631]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
HIF-1 signaling pathway [NCBI:695200] [KEGG:hsa04066] [PUBMED:11902584] [PUBMED:20965423] [PUBMED:20679415] [PUBMED:15031665] [PUBMED:18259201] [PUBMED:22205687] [PUBMED:19364912] [PUBMED:19147540] [PUBMED:15448722] [PUBMED:16234508] [PUBMED:18505681] [PUBMED:20836033] [PUBMED:19861159] [PUBMED:17955264] [PUBMED:22562152]
HIF-2-alpha transcription factor network [NCBI:137956] [Pathway Interaction Database:hif2pathway] [PUBMED:10671489] [PUBMED:11983697] [PUBMED:11823643] [PUBMED:15039136] [PUBMED:19352007] [PUBMED:18356544] [PUBMED:17097563] [PUBMED:16740701] [PUBMED:19541651] [PUBMED:17873906] [PUBMED:12080085] [PUBMED:11292862] [PUBMED:16510872] [PUBMED:19498162] [PUBMED:10353251] [PUBMED:18625704] [PUBMED:15247232] [PUBMED:9079689] [PUBMED:19204094] [PUBMED:17322295] [PUBMED:17804822] [PUBMED:9113979] [PUBMED:12464608] [PUBMED:18434321] [PUBMED:15592504] [PUBMED:10878807] [PUBMED:17324924] [PUBMED:15192019] [PUBMED:9000051] [PUBMED:16611993] [PUBMED:10823831]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha [NCBI:1270418] [REACTOME:R-HSA-1234176] [PUBMED:15247232] [PUBMED:15474027] [PUBMED:12788921] [PUBMED:18184961] [PUBMED:12351678] [PUBMED:11292861] [PUBMED:17434750] [PUBMED:19208626] [PUBMED:12538644] [PUBMED:12615973] [PUBMED:11598268] [PUBMED:21335549] [PUBMED:12912907] [PUBMED:11292862]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Regulation of Hypoxia-inducible Factor (HIF) by oxygen [NCBI:1270416] [REACTOME:R-HSA-1234174] [PUBMED:19704417] [PUBMED:20728359] [PUBMED:21335549] [PUBMED:19339544] [PUBMED:17916722] [PUBMED:18498744] [PUBMED:16724055] [PUBMED:20965423]
Renal cell carcinoma [NCBI:83107] [KEGG:hsa05211] [PUBMED:12351585] [PUBMED:17211469] [PUBMED:16339096] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15611513] [PUBMED:14685170] [PUBMED:15122209]