full name
epoxide hydrolase 1

synonyms
EPHX, EPOX, HYL1, MEH, EPHX1, ENSG00000143819

HGNC
HGNC:3401

Entrez Gene
Gene:2052

ENSEMBL
ENSG00000143819

location
chr: 1
start: 225997797
stop: 226033264
strand: +

OMIM
OMIM:132810: EPHX1 (Autosomal dominant inheritance,Autosomal recessive inheritance)
OMIM:607748: ?Hypercholanemia, familial

transcripts
NM_001136018.2
NM_000120.3

pathways
Bile secretion [NCBI:193146] [KEGG:hsa04976] [PUBMED:11826283] [PUBMED:19273385] [PUBMED:12663868] [PUBMED:15758646] [PUBMED:18837079] [PUBMED:15975683] [PUBMED:17404808] [PUBMED:18377365] [PUBMED:16706681] [PUBMED:10728790] [PUBMED:14659471] [PUBMED:18670431] [PUBMED:12483266] [PUBMED:19273238] [PUBMED:18668439] [PUBMED:18371245] [PUBMED:14999673] [PUBMED:11316487] [PUBMED:18081658] [PUBMED:19482594] [PUBMED:20103563]
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Chemical carcinogenesis [NCBI:673221] [KEGG:hsa05204] [PUBMED:21473878] [PUBMED:15489140] [PUBMED:21255676] [PUBMED:11376689] [PUBMED:15298956] [PUBMED:17445838] [PUBMED:22705365] [PUBMED:9152590] [PUBMED:8759017] [PUBMED:20570348] [PUBMED:11275476] [PUBMED:9202760] [PUBMED:21163908] [PUBMED:10753215] [PUBMED:10913381] [PUBMED:21217854] [PUBMED:15582261] [PUBMED:16959879] [PUBMED:11092599] [PUBMED:20159989] [PUBMED:21234336] [PUBMED:17459420] [PUBMED:9275165] [PUBMED:17292678] [PUBMED:11978484] [PUBMED:11222868] [PUBMED:15660110] [PUBMED:8702479] [PUBMED:9356303] [PUBMED:20232918] [PUBMED:12435844] [PUBMED:19657920] [PUBMED:8951235] [PUBMED:15532073] [PUBMED:16084004] [PUBMED:18066431] [PUBMED:14570033] [PUBMED:16421178] [PUBMED:21154658] [PUBMED:12928348] [PUBMED:19531241] [PUBMED:20669524] [PUBMED:11467078] [PUBMED:22178655] [PUBMED:21456541]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of xenobiotics by cytochrome P450 [NCBI:83031] [KEGG:hsa00980] [PUBMED:9107551] [PUBMED:10570027] [PUBMED:4395686] [PUBMED:10490505] [PUBMED:15987776] [PUBMED:15298956] [PUBMED:15319346] [PUBMED:12487150] [PUBMED:10725110]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]