full name
SUMO1 activating enzyme subunit 1

synonyms
AOS1, HSPC140, SUA1, UBLE1A, SAE1, ENSG00000142230

HGNC
HGNC:30660

Entrez Gene
Gene:10055

ENSEMBL
ENSG00000142230

location
chr: 19
start: 47634080
stop: 47713893
strand: +

transcripts
NM_005500.2
NM_001145714.1
NM_001145713.1
NR_027280.1

pathways
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Processing and activation of SUMO [NCBI:1268739] [REACTOME:R-HSA-3215018] [PUBMED:16253240] [PUBMED:17591783] [PUBMED:11896061] [PUBMED:19923268] [PUBMED:16738315] [PUBMED:12192048] [PUBMED:20462400] [PUBMED:17099700] [PUBMED:17768054] [PUBMED:20674646] [PUBMED:21102611] [PUBMED:17099698] [PUBMED:16738331] [PUBMED:14563852]
SUMO is conjugated to E1 (UBA2:SAE1) [NCBI:1268741] [REACTOME:R-HSA-3065676] [PUBMED:20164921] [PUBMED:19923268] [PUBMED:21102611] [PUBMED:20674646]
SUMO is transferred from E1 to E2 (UBE2I, UBC9) [NCBI:1268742] [REACTOME:R-HSA-3065678] [PUBMED:20462400] [PUBMED:20674646] [PUBMED:21102611] [PUBMED:19923268]
SUMOylation [NCBI:1268738] [REACTOME:R-HSA-2990846] [PUBMED:21102611] [PUBMED:20674646] [PUBMED:23514139] [PUBMED:19923268] [PUBMED:20462400] [PUBMED:17768054]
Ubiquitin mediated proteolysis [NCBI:83056] [KEGG:hsa04120] [PUBMED:16405856] [PUBMED:12944364] [PUBMED:16922408] [PUBMED:17588513] [PUBMED:16922367] [PUBMED:16922370] [PUBMED:16816840]