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Genes
SPHK2
Gene - SPHK2
full name
sphingosine kinase 2
synonyms
SK, SPHK2, ENSG00000063176
HGNC
HGNC:18859
Entrez Gene
Gene:56848
ENSEMBL
ENSG00000063176
location
chr: 19
start: 49122548
stop: 49133974
strand: +
transcripts
NM_020126.4
NM_001204158.2
NM_001243876.1
NM_001204159.2
NM_001204160.2
pathways
Apelin signaling pathway
[NCBI:1492886]
[KEGG:hsa04371]
[PUBMED:23973488]
[PUBMED:16182514]
[PUBMED:21725702]
[PUBMED:22842084]
[PUBMED:27825851]
[PUBMED:27650065]
[PUBMED:22140623]
[PUBMED:23943882]
[PUBMED:26944568]
[PUBMED:24055369]
[PUBMED:26385179]
[PUBMED:26143239]
[PUBMED:22028387]
[PUBMED:26254105]
[PUBMED:26756969]
[PUBMED:22995518]
[PUBMED:27979574]
[PUBMED:23924696]
[PUBMED:21464822]
[PUBMED:25914650]
[PUBMED:24990699]
[PUBMED:26607438]
[PUBMED:25164121]
[PUBMED:25275559]
[PUBMED:25139773]
[PUBMED:25931124]
[PUBMED:19093215]
[PUBMED:20539939]
[PUBMED:25652330]
[PUBMED:18272138]
[PUBMED:23603510]
Calcium signaling pathway
[NCBI:83050]
[KEGG:hsa04020]
[PUBMED:11080247]
[PUBMED:14572802]
[PUBMED:11413485]
[PUBMED:22129055]
[PUBMED:10508738]
[PUBMED:15000521]
[PUBMED:9235901]
[PUBMED:7861177]
[PUBMED:9149541]
[PUBMED:14517314]
[PUBMED:15111104]
[PUBMED:11698232]
[PUBMED:10331643]
[PUBMED:12838335]
[PUBMED:8125957]
[PUBMED:19172794]
[PUBMED:10997573]
[PUBMED:21338471]
[PUBMED:11299192]
[PUBMED:22002090]
[PUBMED:12972622]
Ceramide signaling pathway
[NCBI:138023]
[Pathway Interaction Database:ceramide_pathway]
[PUBMED:11350735]
[PUBMED:10400650]
[PUBMED:9287216]
[PUBMED:9488730]
[PUBMED:8702918]
[PUBMED:10969079]
[PUBMED:10433354]
[PUBMED:14739942]
[PUBMED:9446561]
[PUBMED:8808629]
[PUBMED:8681376]
[PUBMED:7477354]
[PUBMED:14689449]
[PUBMED:12866359]
[PUBMED:9873064]
[PUBMED:8933152]
[PUBMED:10438487]
[PUBMED:15881228]
[PUBMED:10508159]
[PUBMED:7519779]
[PUBMED:8387486]
[PUBMED:12154098]
[PUBMED:7559390]
[PUBMED:12486111]
[PUBMED:14670935]
[PUBMED:15901738]
[PUBMED:15051724]
[PUBMED:8393446]
[PUBMED:9094715]
[PUBMED:11723139]
[PUBMED:10395296]
[PUBMED:8681377]
[PUBMED:11148216]
[PUBMED:12566438]
[PUBMED:15164763]
[PUBMED:10026132]
[PUBMED:10962008]
Fc gamma R-mediated phagocytosis
[NCBI:114228]
[KEGG:hsa04666]
[PUBMED:11304556]
[PUBMED:11244038]
[PUBMED:10755615]
[PUBMED:17308335]
[PUBMED:12821647]
[PUBMED:15466916]
[PUBMED:17050193]
[PUBMED:11228151]
[PUBMED:12488490]
[PUBMED:10224668]
[PUBMED:11708889]
[PUBMED:9581795]
[PUBMED:10586078]
[PUBMED:9417101]
[PUBMED:15485887]
[PUBMED:18322649]
[PUBMED:10577498]
[PUBMED:10376013]
[PUBMED:10601359]
[PUBMED:9545263]
IL12-mediated signaling events
[NCBI:137922]
[Pathway Interaction Database:il12_2pathway]
[PUBMED:12874225]
[PUBMED:12221108]
[PUBMED:16380506]
[PUBMED:9768751]
[PUBMED:17114419]
[PUBMED:10358173]
[PUBMED:9890938]
[PUBMED:12213961]
[PUBMED:11120802]
[PUBMED:9202126]
[PUBMED:16641133]
[PUBMED:10198225]
[PUBMED:16763563]
[PUBMED:15728489]
[PUBMED:8103068]
[PUBMED:10903740]
[PUBMED:10201984]
[PUBMED:7638186]
[PUBMED:11894097]
[PUBMED:16220539]
[PUBMED:10961885]
[PUBMED:7594594]
[PUBMED:17110450]
[PUBMED:9582275]
[PUBMED:10320373]
[PUBMED:7528775]
[PUBMED:11207258]
[PUBMED:9038232]
[PUBMED:15522880]
[PUBMED:11175814]
[PUBMED:9531298]
[PUBMED:7722452]
[PUBMED:8943050]
[PUBMED:7553885]
[PUBMED:9454765]
Metabolic pathways
[NCBI:132956]
[KEGG:hsa01100]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins
[NCBI:1270001]
[REACTOME:R-HSA-556833]
Phospholipase D signaling pathway
[NCBI:1311074]
[KEGG:hsa04072]
[PUBMED:9310372]
[PUBMED:9119890]
[PUBMED:15310762]
[PUBMED:18936782]
[PUBMED:24990952]
[PUBMED:14769825]
[PUBMED:21936578]
[PUBMED:10666319]
[PUBMED:17210675]
[PUBMED:19264150]
[PUBMED:23076158]
[PUBMED:17054901]
[PUBMED:16622417]
[PUBMED:10807766]
[PUBMED:12217395]
[PUBMED:11042115]
[PUBMED:19815110]
[PUBMED:24995811]
[PUBMED:16143829]
[PUBMED:8135758]
[PUBMED:11991733]
[PUBMED:19410013]
[PUBMED:17245604]
Sphingolipid de novo biosynthesis
[NCBI:1270098]
[REACTOME:R-HSA-1660661]
[PUBMED:12011104]
[PUBMED:20919643]
Sphingolipid metabolism
[NCBI:82994]
[KEGG:hsa00600]
[NCBI:1270097]
[REACTOME:R-HSA-428157]
[PUBMED:11305904]
[PUBMED:10652340]
[PUBMED:12011104]
[PUBMED:10366774]
[PUBMED:8457204]
[PUBMED:18165232]
[PUBMED:1495423]
[PUBMED:18216770]
Sphingolipid signaling pathway
[NCBI:1144995]
[KEGG:hsa04071]
[PUBMED:23919551]
[PUBMED:21705677]
[PUBMED:18675379]
[PUBMED:20534702]
[PUBMED:15999095]
[PUBMED:16470226]
[PUBMED:11001563]
[PUBMED:17913601]
[PUBMED:17161984]
[PUBMED:22654878]
[PUBMED:17438574]
[PUBMED:18216770]
[PUBMED:11418646]
[PUBMED:10880336]
[PUBMED:15451787]
[PUBMED:25309325]
[PUBMED:18403224]
Sphingosine 1-phosphate (S1P) pathway
[NCBI:137931]
[Pathway Interaction Database:s1p_meta_pathway]
[PUBMED:12815058]
[PUBMED:17050692]
[PUBMED:9854026]
[PUBMED:16584625]
[PUBMED:10617617]
[PUBMED:16520486]
[PUBMED:14570870]
[PUBMED:11705398]
[PUBMED:16996023]
[PUBMED:12531554]
[PUBMED:12761884]
Sphingosine degradation
[NCBI:413389]
[KEGG:hsa_M00100]
Tuberculosis
[NCBI:213780]
[KEGG:hsa05152]
[PUBMED:20199890]
[PUBMED:21274449]
[PUBMED:17359235]
[PUBMED:20415982]
[PUBMED:18541216]
[PUBMED:19369951]
[PUBMED:15083155]
[PUBMED:11378475]
[PUBMED:15228522]
[PUBMED:19634703]
[PUBMED:21274433]
[PUBMED:19563525]
[PUBMED:18407066]
[PUBMED:18288961]
[PUBMED:16200082]
[PUBMED:17785780]
[PUBMED:11932234]
VEGF signaling pathway
[NCBI:83066]
[KEGG:hsa04370]
[PUBMED:11741095]
[PUBMED:16104843]
[PUBMED:14641020]
[PUBMED:15338053]
[PUBMED:14724572]
[PUBMED:12391145]
[PUBMED:13678960]
[PUBMED:15602010]
sphingosine and sphingosine-1-phosphate metabolism
[NCBI:545351]
[BIOCYC:HUMAN_PWY3DJ-11470]
[PUBMED:15258913]
[PUBMED:12531549]