full name
polynucleotide kinase 3'-phosphatase

synonyms
EIEE10, MCSZ, PNK, PNKP, ENSG00000039650

HGNC
HGNC:9154

Entrez Gene
Gene:11284

ENSEMBL
ENSG00000039650

location
chr: 19
start: 50364460
stop: 50370840
strand: -

OMIM
OMIM:605610: PNKP
OMIM:605589: ?Charcot-Marie-Tooth disease, type 2B2
OMIM:616267: Ataxia-oculomotor apraxia 4
OMIM:613402: Microcephaly, seizures, and developmental delay

transcripts
NM_007254.3

pathways
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway [NCBI:1270363] [REACTOME:R-HSA-5649702] [PUBMED:16982218] [PUBMED:15260972] [PUBMED:11163244]
Base Excision Repair [NCBI:1270351] [REACTOME:R-HSA-73884] [PUBMED:11937636] [PUBMED:10583946]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Resolution of Abasic Sites (AP sites) [NCBI:1270359] [REACTOME:R-HSA-73933] [PUBMED:11601988] [PUBMED:15260972] [PUBMED:17395641] [PUBMED:19329425] [PUBMED:9804798] [PUBMED:15556996] [PUBMED:9214649] [PUBMED:7608159] [PUBMED:11440997] [PUBMED:15871698] [PUBMED:9207062] [PUBMED:16982218] [PUBMED:8978692]