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Genes
KLK3
Gene - KLK3
full name
kallikrein related peptidase 3
synonyms
APS, hK3, KLK2A1, PSA, KLK3, ENSG00000142515
HGNC
HGNC:6364
Entrez Gene
Gene:354
ENSEMBL
ENSG00000142515
location
chr: 19
start: 51358171
stop: 51364020
strand: +
transcripts
NM_001030047.1
NM_001648.2
NM_001030048.1
pathways
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
[NCBI:1269513]
[REACTOME:R-HSA-5625886]
[PUBMED:18066052]
[PUBMED:16079795]
[PUBMED:12514133]
Coregulation of Androgen receptor activity
[NCBI:138085]
[Pathway Interaction Database:ar_pathway]
[PUBMED:16724108]
[PUBMED:16027218]
[PUBMED:11818503]
[PUBMED:17277772]
[PUBMED:11719514]
[PUBMED:15833840]
[PUBMED:16384856]
[PUBMED:14645241]
[PUBMED:12218053]
[PUBMED:11016951]
[PUBMED:12621049]
[PUBMED:15784617]
[PUBMED:16446156]
[PUBMED:17110431]
[PUBMED:16254014]
[PUBMED:17698582]
[PUBMED:15131260]
[PUBMED:16705743]
[PUBMED:11682623]
[PUBMED:17192406]
[PUBMED:15882980]
[PUBMED:10934038]
[PUBMED:12165860]
[PUBMED:11856738]
[PUBMED:16720717]
[PUBMED:9710597]
[PUBMED:14609956]
[PUBMED:17170703]
[PUBMED:10383460]
[PUBMED:14576337]
[PUBMED:12941811]
[PUBMED:14612401]
[PUBMED:17975004]
[PUBMED:12799378]
[PUBMED:15790678]
[PUBMED:8643607]
[PUBMED:11792840]
[PUBMED:16603237]
[PUBMED:16079795]
[PUBMED:16951154]
[PUBMED:15166229]
[PUBMED:17142810]
[PUBMED:12361945]
[PUBMED:11439351]
[PUBMED:15640154]
[PUBMED:17909037]
[PUBMED:15539430]
[PUBMED:11792709]
[PUBMED:11931767]
[PUBMED:10344732]
[PUBMED:10428808]
FOXA1 transcription factor network
[NCBI:137979]
[Pathway Interaction Database:hnf3apathway]
[PUBMED:9427758]
[PUBMED:16087863]
[PUBMED:12750453]
[PUBMED:12441652]
[PUBMED:11763995]
[PUBMED:8441395]
[PUBMED:8164696]
[PUBMED:2786140]
[PUBMED:8071346]
[PUBMED:8598458]
[PUBMED:16331276]
[PUBMED:16214823]
[PUBMED:10049364]
[PUBMED:15987773]
[PUBMED:10073575]
[PUBMED:8058060]
[PUBMED:16980581]
[PUBMED:9685261]
[PUBMED:16009131]
Metabolism of proteins
[NCBI:1268677]
[REACTOME:R-HSA-392499]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Prostate cancer
[NCBI:83111]
[KEGG:hsa05215]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11527574]
[PUBMED:11750244]
[PUBMED:16551847]
[PUBMED:10835690]
[PUBMED:8069858]
[PUBMED:15724144]
[PUBMED:10453277]
[PUBMED:15082523]
[PUBMED:9422516]
RHO GTPase Effectors
[NCBI:1269509]
[REACTOME:R-HSA-195258]
[PUBMED:9694656]
[PUBMED:18066052]
[PUBMED:11018042]
[PUBMED:10470034]
[PUBMED:8702756]
[PUBMED:21730051]
[PUBMED:8571126]
[PUBMED:19513348]
[PUBMED:17244649]
[PUBMED:11145705]
[PUBMED:24128008]
[PUBMED:23716662]
[PUBMED:8617235]
[PUBMED:8543060]
[PUBMED:11804587]
[PUBMED:24969695]
[PUBMED:12635176]
[PUBMED:12778124]
[PUBMED:18006505]
[PUBMED:1660188]
[PUBMED:21351730]
[PUBMED:16507994]
[PUBMED:14595335]
[PUBMED:10072071]
[PUBMED:10591629]
[PUBMED:10753910]
[PUBMED:23875749]
[PUBMED:17151359]
[PUBMED:10652353]
[PUBMED:12221077]
[PUBMED:10559936]
[PUBMED:12783890]
[PUBMED:11948177]
[PUBMED:18237546]
[PUBMED:16079795]
[PUBMED:10924361]
[PUBMED:14514689]
[PUBMED:8107774]
[PUBMED:8756646]
[PUBMED:16979770]
[PUBMED:16636067]
[PUBMED:9751706]
[PUBMED:10619026]
[PUBMED:23444367]
[PUBMED:15546864]
[PUBMED:12473120]
[PUBMED:8816443]
[PUBMED:9199170]
[PUBMED:12514133]
[PUBMED:16762923]
[PUBMED:12110184]
[PUBMED:16431929]
[PUBMED:10975528]
[PUBMED:10940294]
[PUBMED:9535855]
[PUBMED:7559638]
[PUBMED:11162552]
[PUBMED:19737400]
[PUBMED:9988689]
[PUBMED:12732141]
[PUBMED:8798539]
[PUBMED:24914801]
[PUBMED:11689693]
[PUBMED:8769096]
[PUBMED:9368021]
RHO GTPases activate PKNs
[NCBI:1269512]
[REACTOME:R-HSA-5625740]
[PUBMED:21351730]
[PUBMED:21749319]
[PUBMED:10753910]
[PUBMED:18429822]
[PUBMED:9175763]
[PUBMED:12783890]
[PUBMED:14514689]
[PUBMED:10924361]
[PUBMED:7673228]
[PUBMED:10619026]
[PUBMED:10467162]
[PUBMED:11134534]
[PUBMED:9030526]
[PUBMED:9988689]
[PUBMED:19723632]
[PUBMED:24128008]
[PUBMED:18006505]
Regulation of Androgen receptor activity
[NCBI:138027]
[Pathway Interaction Database:ar_tf_pathway]
[PUBMED:15650026]
[PUBMED:17045208]
[PUBMED:10364196]
[PUBMED:16860317]
[PUBMED:10611280]
[PUBMED:10930412]
[PUBMED:1525041]
[PUBMED:10779504]
[PUBMED:12514133]
[PUBMED:1985913]
[PUBMED:11931767]
[PUBMED:17011549]
[PUBMED:15640443]
[PUBMED:16322096]
[PUBMED:15923603]
[PUBMED:14985354]
[PUBMED:15743818]
[PUBMED:12949936]
[PUBMED:11994312]
[PUBMED:10567371]
[PUBMED:11875111]
[PUBMED:15604291]
[PUBMED:12890669]
[PUBMED:14729952]
[PUBMED:9211894]
[PUBMED:9162033]
[PUBMED:16705743]
[PUBMED:16849544]
[PUBMED:16923962]
[PUBMED:11591700]
[PUBMED:16051670]
[PUBMED:8643509]
[PUBMED:17108144]
[PUBMED:16914734]
[PUBMED:12682292]
[PUBMED:3353726]
[PUBMED:11585838]
[PUBMED:16282370]
[PUBMED:10381882]
[PUBMED:15199155]
[PUBMED:16455820]
[PUBMED:14612401]
[PUBMED:10625666]
[PUBMED:17679089]
[PUBMED:16461774]
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
[NCBI:1268755]
[REACTOME:R-HSA-381426]
[PUBMED:17047378]
[PUBMED:12904166]
[PUBMED:12379487]
[PUBMED:11606061]
[PUBMED:12466191]
[PUBMED:11751371]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]