full name
ADP ribosylation factor 1

synonyms
ARF1, ENSG00000143761

HGNC
HGNC:652

Entrez Gene
Gene:375

ENSEMBL
ENSG00000143761

location
chr: 1
start: 228270361
stop: 228286913
strand: +

OMIM
OMIM:103180: ARF1
OMIM:618185: Periventricular nodular heterotopia 8

transcripts
NM_001024226.1
NM_001658.3
NM_001024227.1
NM_001024228.1

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Arf1 pathway [NCBI:137927] [Pathway Interaction Database:arf_3pathway] [PUBMED:11346801] [PUBMED:9694811] [PUBMED:9819391] [PUBMED:12376537] [PUBMED:8498538] [PUBMED:9405360] [PUBMED:11301005] [PUBMED:15793564] [PUBMED:11970962] [PUBMED:8530346] [PUBMED:10747089] [PUBMED:10212200] [PUBMED:9388229] [PUBMED:7961749] [PUBMED:10652308] [PUBMED:15781476] [PUBMED:11342560] [PUBMED:16100119] [PUBMED:9826657] [PUBMED:15202998] [PUBMED:10848997] [PUBMED:8144664] [PUBMED:9268368]
Arf6 downstream pathway [NCBI:138038] [Pathway Interaction Database:arf6downstreampathway] [PUBMED:12388770] [PUBMED:14565977] [PUBMED:10036235] [PUBMED:14764880] [PUBMED:12447393] [PUBMED:9312003] [PUBMED:17077126] [PUBMED:17363898] [PUBMED:14505574] [PUBMED:16280360] [PUBMED:17628206] [PUBMED:15601896] [PUBMED:10913182] [PUBMED:16452216] [PUBMED:7753201] [PUBMED:15210957] [PUBMED:16880525] [PUBMED:16181626] [PUBMED:17640372] [PUBMED:11481345] [PUBMED:17409355] [PUBMED:12379803] [PUBMED:18084281] [PUBMED:10589680] [PUBMED:11532961] [PUBMED:17353194] [PUBMED:8769418] [PUBMED:10779358] [PUBMED:18026091] [PUBMED:12509462] [PUBMED:15087504] [PUBMED:9664047]
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:16807922] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
COPI-dependent Golgi-to-ER retrograde traffic [NCBI:1383042] [REACTOME:R-HSA-6811434] [PUBMED:25364732] [PUBMED:23732476] [PUBMED:23378591] [PUBMED:10469566] [PUBMED:24119662] [PUBMED:23873287] [PUBMED:9813082] [PUBMED:19854180] [PUBMED:8001155]
COPI-mediated anterograde transport [NCBI:1339109] [REACTOME:R-HSA-6807878] [PUBMED:9323141] [PUBMED:15632110] [PUBMED:10825291] [PUBMED:9288971] [PUBMED:23378591] [PUBMED:8334707] [PUBMED:22013193] [PUBMED:23732476]
Class I PI3K signaling events [NCBI:138022] [Pathway Interaction Database:pi3kcipathway] [PUBMED:9072969] [PUBMED:15296756] [PUBMED:12780340] [PUBMED:11154281] [PUBMED:9326591] [PUBMED:10357815] [PUBMED:10586033] [PUBMED:9824312] [PUBMED:11001876] [PUBMED:9593664] [PUBMED:10770799] [PUBMED:9442017] [PUBMED:8643691] [PUBMED:7627555] [PUBMED:11102801] [PUBMED:9307042] [PUBMED:10506192] [PUBMED:11804589] [PUBMED:15879121] [PUBMED:11226282] [PUBMED:18024423] [PUBMED:8629002] [PUBMED:9550703] [PUBMED:14688341] [PUBMED:16418224] [PUBMED:8945478] [PUBMED:10333475] [PUBMED:10764758] [PUBMED:9417041] [PUBMED:8052307]
Clathrin derived vesicle budding [NCBI:1269881] [REACTOME:R-HSA-421837]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
ER to Golgi Anterograde Transport [NCBI:1268726] [REACTOME:R-HSA-199977] [PUBMED:11252894]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
Golgi Associated Vesicle Biogenesis [NCBI:1269882] [REACTOME:R-HSA-432722]
Golgi-to-ER retrograde transport [NCBI:1383041] [REACTOME:R-HSA-8856688] [PUBMED:23732476] [PUBMED:23378591] [PUBMED:25233431]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
Host Interactions of HIV factors [NCBI:1269091] [REACTOME:R-HSA-162909]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Intra-Golgi and retrograde Golgi-to-ER traffic [NCBI:1383038] [REACTOME:R-HSA-6811442] [PUBMED:11756463] [PUBMED:23839779] [PUBMED:21436057] [PUBMED:22013193] [PUBMED:21421921] [PUBMED:25233431] [PUBMED:16157178] [PUBMED:12121415] [PUBMED:25343031] [PUBMED:24068461] [PUBMED:19575639]
Intra-Golgi traffic [NCBI:1383040] [REACTOME:R-HSA-6811438] [PUBMED:22013193] [PUBMED:21436057] [PUBMED:23881164] [PUBMED:23846822] [PUBMED:23732476] [PUBMED:25708460] [PUBMED:25343031] [PUBMED:23839779] [PUBMED:22581368]
Legionellosis [NCBI:469200] [KEGG:hsa05134] [PUBMED:19021631] [PUBMED:19157961] [PUBMED:20375353] [PUBMED:19478083] [PUBMED:18284575] [PUBMED:19386084] [PUBMED:19666608] [PUBMED:15972519] [PUBMED:18549456] [PUBMED:1721820] [PUBMED:17124169] [PUBMED:19687203] [PUBMED:18363881] [PUBMED:19343209] [PUBMED:20941588] [PUBMED:16824952] [PUBMED:18281405] [PUBMED:18048909] [PUBMED:16495539] [PUBMED:12427954]
Lysosome Vesicle Biogenesis [NCBI:1269883] [REACTOME:R-HSA-432720]
MHC class II antigen presentation [NCBI:1269200] [REACTOME:R-HSA-2132295] [PUBMED:19703008] [PUBMED:9316394] [PUBMED:11684289] [PUBMED:19217269] [PUBMED:8689559]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Nef Mediated CD4 Down-regulation [NCBI:1269105] [REACTOME:R-HSA-167590] [PUBMED:11264384] [PUBMED:2014052] [PUBMED:8124721] [PUBMED:7831289] [PUBMED:8756680]
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters [NCBI:1269102] [REACTOME:R-HSA-164938] [PUBMED:9811606] [PUBMED:11208076] [PUBMED:9564030] [PUBMED:9586638] [PUBMED:12486136] [PUBMED:9811611] [PUBMED:9384576] [PUBMED:9736718]
PI Metabolism [NCBI:1270073] [REACTOME:R-HSA-1483255] [PUBMED:17035995] [PUBMED:18216768] [PUBMED:17330069] [PUBMED:15170460] [PUBMED:16828287] [PUBMED:18726176] [PUBMED:20861159] [PUBMED:19196647] [PUBMED:20043944] [PUBMED:20192774] [PUBMED:18784754] [PUBMED:20559318] [PUBMED:18216767] [PUBMED:17605038] [PUBMED:15269334]
Phospholipase D signaling pathway [NCBI:1311074] [KEGG:hsa04072] [PUBMED:9310372] [PUBMED:9119890] [PUBMED:15310762] [PUBMED:18936782] [PUBMED:24990952] [PUBMED:14769825] [PUBMED:21936578] [PUBMED:10666319] [PUBMED:17210675] [PUBMED:19264150] [PUBMED:23076158] [PUBMED:17054901] [PUBMED:16622417] [PUBMED:10807766] [PUBMED:12217395] [PUBMED:11042115] [PUBMED:19815110] [PUBMED:24995811] [PUBMED:16143829] [PUBMED:8135758] [PUBMED:11991733] [PUBMED:19410013] [PUBMED:17245604]
Phospholipid metabolism [NCBI:1270053] [REACTOME:R-HSA-1483257] [PUBMED:9242906]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Synthesis of PIPs at the Golgi membrane [NCBI:1270075] [REACTOME:R-HSA-1660514] [PUBMED:11279162] [PUBMED:17556371] [PUBMED:10766823] [PUBMED:10559940] [PUBMED:10805725] [PUBMED:14527956] [PUBMED:18950639]
Synthesis of PIPs at the plasma membrane [NCBI:1270077] [REACTOME:R-HSA-1660499] [PUBMED:16399794] [PUBMED:12646134] [PUBMED:10224048] [PUBMED:9113989] [PUBMED:9211928] [PUBMED:12536145] [PUBMED:22647598] [PUBMED:11733541] [PUBMED:9660759] [PUBMED:19896968]
The role of Nef in HIV-1 replication and disease pathogenesis [NCBI:1269100] [REACTOME:R-HSA-164952] [PUBMED:16354571]
Transport to the Golgi and subsequent modification [NCBI:1268725] [REACTOME:R-HSA-948021] [PUBMED:12717434] [PUBMED:10412983] [PUBMED:3594573]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]
Vibrio cholerae infection [NCBI:83101] [KEGG:hsa05110] [PUBMED:12671039] [PUBMED:17464284] [PUBMED:17156122] [PUBMED:11207565] [PUBMED:13679513] [PUBMED:11032799] [PUBMED:14659695] [PUBMED:11953326] [PUBMED:10942706] [PUBMED:12102686] [PUBMED:11349009] [PUBMED:11292584] [PUBMED:12403808] [PUBMED:11454785] [PUBMED:15204437]
trans-Golgi Network Vesicle Budding [NCBI:1269880] [REACTOME:R-HSA-199992] [PUBMED:11252894]