full name
FK506 binding protein 1A

synonyms
FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE, FKBP1A, ENSG00000088832

HGNC
HGNC:3711

Entrez Gene
Gene:2280

ENSEMBL
ENSG00000088832

location
chr: 20
start: 1349621
stop: 1373816
strand: -

transcripts
NM_001199786.1
NM_000801.4
NM_054014.3

pathways
ALK1 pathway [NCBI:137985] [Pathway Interaction Database:alk1_2pathway]
ALK1 signaling events [NCBI:137968] [Pathway Interaction Database:alk1pathway] [PUBMED:9748228] [PUBMED:17071858] [PUBMED:14580334] [PUBMED:9920917] [PUBMED:17911401] [PUBMED:17311849] [PUBMED:8140412] [PUBMED:17068149] [PUBMED:8242742] [PUBMED:16571110] [PUBMED:9872992] [PUBMED:8612709] [PUBMED:18065769] [PUBMED:1326540] [PUBMED:15385967] [PUBMED:8756725] [PUBMED:11927558] [PUBMED:10187774] [PUBMED:8294451] [PUBMED:15702480] [PUBMED:10716993] [PUBMED:17540773] [PUBMED:19592636]
ALK2 signaling events [NCBI:137983] [Pathway Interaction Database:alk2pathway] [PUBMED:11376112] [PUBMED:8756725] [PUBMED:11376113] [PUBMED:8006002] [PUBMED:9748228] [PUBMED:9920917]
Alpha-synuclein signaling [NCBI:137913] [Pathway Interaction Database:alphasynuclein_pathway] [PUBMED:12551928] [PUBMED:15671022] [PUBMED:12887682] [PUBMED:14991825] [PUBMED:11431533] [PUBMED:11588587] [PUBMED:16030137] [PUBMED:15845543] [PUBMED:11590439] [PUBMED:12096713] [PUBMED:11687285] [PUBMED:15978696] [PUBMED:10407019] [PUBMED:11078745] [PUBMED:16403519] [PUBMED:14985429] [PUBMED:14645218] [PUBMED:12787066] [PUBMED:11292651] [PUBMED:12421356] [PUBMED:15944382] [PUBMED:10567343] [PUBMED:11744621] [PUBMED:15935068] [PUBMED:12928483] [PUBMED:11821392] [PUBMED:10852916]
Calcium signaling in the CD4+ TCR pathway [NCBI:137941] [Pathway Interaction Database:tcrcalciumpathway] [PUBMED:8284217] [PUBMED:10816557] [PUBMED:10970869] [PUBMED:8240350] [PUBMED:8623163] [PUBMED:1715244] [PUBMED:1715516] [PUBMED:16406492] [PUBMED:9655484] [PUBMED:8397339] [PUBMED:10861295] [PUBMED:9047239] [PUBMED:293720] [PUBMED:7891702] [PUBMED:12925851] [PUBMED:9660798] [PUBMED:1377362] [PUBMED:12065418] [PUBMED:8441422] [PUBMED:7528941] [PUBMED:1737937] [PUBMED:12809556] [PUBMED:9545284] [PUBMED:11254715] [PUBMED:10878360] [PUBMED:10593895]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Loss of Function of TGFBR1 in Cancer [NCBI:1268903] [REACTOME:R-HSA-3656534] [PUBMED:11406536] [PUBMED:11477574] [PUBMED:19147584] [PUBMED:21358634] [PUBMED:9850059] [PUBMED:9809982] [PUBMED:10515889]
Loss of Function of TGFBR2 in Cancer [NCBI:1268900] [REACTOME:R-HSA-3642278] [PUBMED:15256431] [PUBMED:9927040] [PUBMED:17047044] [PUBMED:17339425] [PUBMED:7761852]
Role of Calcineurin-dependent NFAT signaling in lymphocytes [NCBI:137953] [Pathway Interaction Database:nfat_3pathway] [PUBMED:15743762] [PUBMED:9109491] [PUBMED:1715244] [PUBMED:15121840] [PUBMED:10195903] [PUBMED:10788511] [PUBMED:9630228] [PUBMED:9834092] [PUBMED:9655484] [PUBMED:10933397] [PUBMED:11030334] [PUBMED:8684469] [PUBMED:10861295] [PUBMED:15117942] [PUBMED:12351631] [PUBMED:15902271] [PUBMED:16406492] [PUBMED:10944115] [PUBMED:10611249] [PUBMED:15733859] [PUBMED:15757646] [PUBMED:9768749] [PUBMED:9072970] [PUBMED:12510191] [PUBMED:9585406] [PUBMED:293720] [PUBMED:12925851] [PUBMED:16943420] [PUBMED:11823475] [PUBMED:16141075] [PUBMED:9374467] [PUBMED:9660798] [PUBMED:7528941] [PUBMED:11356833] [PUBMED:10593895] [PUBMED:10866678] [PUBMED:9171236] [PUBMED:12809556] [PUBMED:10652349] [PUBMED:12021260] [PUBMED:16455648]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by TGF-beta Receptor Complex [NCBI:1269523] [REACTOME:R-HSA-170834] [PUBMED:19648010]
Signaling by TGF-beta Receptor Complex in Cancer [NCBI:1268894] [REACTOME:R-HSA-3304351] [PUBMED:9214508] [PUBMED:7664267] [PUBMED:8553070] [PUBMED:8752208] [PUBMED:21358634] [PUBMED:7777546] [PUBMED:23139211] [PUBMED:8078588] [PUBMED:19834456] [PUBMED:9809982] [PUBMED:22710176] [PUBMED:7761852] [PUBMED:9927040] [PUBMED:17936557] [PUBMED:12150994] [PUBMED:11406536] [PUBMED:2418960] [PUBMED:7585632] [PUBMED:11477574]
TGF-beta receptor signaling [NCBI:138024] [Pathway Interaction Database:tgfbrpathway] [PUBMED:12118366] [PUBMED:8242743] [PUBMED:15221015] [PUBMED:9335507] [PUBMED:11278302] [PUBMED:16601693] [PUBMED:8391934] [PUBMED:1333888] [PUBMED:11438668] [PUBMED:17327236] [PUBMED:2879635] [PUBMED:11483955] [PUBMED:12717440] [PUBMED:8047140] [PUBMED:8576253] [PUBMED:9865696] [PUBMED:9346908] [PUBMED:17197390] [PUBMED:8533096] [PUBMED:8756725] [PUBMED:10615055] [PUBMED:10934479] [PUBMED:16251192] [PUBMED:7706248] [PUBMED:15946939] [PUBMED:7774578] [PUBMED:7988555] [PUBMED:11278251] [PUBMED:11027280] [PUBMED:17420258] [PUBMED:9169454] [PUBMED:12151385] [PUBMED:10757800] [PUBMED:12543979] [PUBMED:12475967] [PUBMED:9679059] [PUBMED:17673906] [PUBMED:9774674] [PUBMED:8893010] [PUBMED:1544886] [PUBMED:12958365] [PUBMED:12110587] [PUBMED:9233797] [PUBMED:11163210] [PUBMED:15496141] [PUBMED:7693660] [PUBMED:14657019] [PUBMED:12429842] [PUBMED:11124802] [PUBMED:11389444] [PUBMED:8798398] [PUBMED:15356634] [PUBMED:17272273] [PUBMED:1657407] [PUBMED:12589052] [PUBMED:11016919] [PUBMED:14718519] [PUBMED:10777621] [PUBMED:17384642] [PUBMED:1310899] [PUBMED:9856985] [PUBMED:10519551] [PUBMED:9155023] [PUBMED:12134160] [PUBMED:9215638] [PUBMED:12134149] [PUBMED:16157589] [PUBMED:12356868] [PUBMED:11387212] [PUBMED:12034739] [PUBMED:11739411] [PUBMED:15761148] [PUBMED:9463378] [PUBMED:11583628] [PUBMED:15684397] [PUBMED:8947046] [PUBMED:11781097]
TGF-beta receptor signaling activates SMADs [NCBI:1269524] [REACTOME:R-HSA-2173789] [PUBMED:9346966] [PUBMED:15350224] [PUBMED:7737999] [PUBMED:11100470] [PUBMED:7693660] [PUBMED:9670020] [PUBMED:15564041] [PUBMED:9233797] [PUBMED:20207738] [PUBMED:11779505] [PUBMED:18243111] [PUBMED:8947046] [PUBMED:1333888] [PUBMED:9311995] [PUBMED:12482908] [PUBMED:8980228] [PUBMED:8242743] [PUBMED:9865696] [PUBMED:8047140] [PUBMED:21423151]
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) [NCBI:1269526] [REACTOME:R-HSA-2173791] [PUBMED:14657501] [PUBMED:15761148]
TGFBR1 KD Mutants in Cancer [NCBI:1268905] [REACTOME:R-HSA-3656532] [PUBMED:11406536] [PUBMED:11477574] [PUBMED:21358634] [PUBMED:9809982]
TGFBR1 LBD Mutants in Cancer [NCBI:1268904] [REACTOME:R-HSA-3656535] [PUBMED:21358634] [PUBMED:23525077] [PUBMED:5173258]
TGFBR2 Kinase Domain Mutants in Cancer [NCBI:1268902] [REACTOME:R-HSA-3645790] [PUBMED:9121777] [PUBMED:9927040] [PUBMED:7585632] [PUBMED:10789724]