full name
CD40 molecule

synonyms
Bp50, CDW40, p50, TNFRSF5, CD40, ENSG00000101017

HGNC
HGNC:11919

Entrez Gene
Gene:958

ENSEMBL
ENSG00000101017

location
chr: 20
start: 44746899
stop: 44758384
strand: +

OMIM
OMIM:109535: CD40 (Autosomal recessive inheritance)
OMIM:606843: Immunodeficiency with hyper-IgM, type 3

transcripts
NM_001250.4
NM_152854.2

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Allograft rejection [NCBI:83123] [KEGG:hsa05330] [PUBMED:8835634] [PUBMED:12023610] [PUBMED:12563298] [PUBMED:17445565] [PUBMED:12216939] [PUBMED:14710779] [PUBMED:10746853] [PUBMED:10571983] [PUBMED:10331992] [PUBMED:10667806]
Asthma [NCBI:83120] [KEGG:hsa05310] [PUBMED:11686879] [PUBMED:17364144] [PUBMED:10811837] [PUBMED:11477111] [PUBMED:18274559] [PUBMED:11172168] [PUBMED:18274560] [PUBMED:10719286] [PUBMED:12093011] [PUBMED:17976144] [PUBMED:17133123]
Autoimmune thyroid disease [NCBI:83121] [KEGG:hsa05320] [PUBMED:15132715] [PUBMED:12192541] [PUBMED:17192582] [PUBMED:9534029] [PUBMED:11396701] [PUBMED:11913070] [PUBMED:15049952] [PUBMED:11577986] [PUBMED:15762980]
CD40/CD40L signaling [NCBI:138061] [Pathway Interaction Database:cd40_pathway] [PUBMED:11967542] [PUBMED:11304555] [PUBMED:11714736] [PUBMED:17878343] [PUBMED:12354380] [PUBMED:11406619] [PUBMED:9133417] [PUBMED:7527023] [PUBMED:18997794] [PUBMED:1374165] [PUBMED:1385114] [PUBMED:12958312] [PUBMED:10764746] [PUBMED:11909853] [PUBMED:10318845] [PUBMED:7533327] [PUBMED:16260598] [PUBMED:18997792] [PUBMED:12818164] [PUBMED:10748139] [PUBMED:9718306] [PUBMED:10395671] [PUBMED:17878362] [PUBMED:7544915] [PUBMED:12370254] [PUBMED:8910514] [PUBMED:17143273] [PUBMED:10433725] [PUBMED:14981114] [PUBMED:16622006] [PUBMED:12122011] [PUBMED:12133933]
Cell adhesion molecules (CAMs) [NCBI:83069] [KEGG:hsa04514] [PUBMED:15923648] [PUBMED:12500939] [PUBMED:15056568] [PUBMED:14519386] [PUBMED:12234363] [PUBMED:10964748] [PUBMED:15071551] [PUBMED:15551862] [PUBMED:14690046] [PUBMED:9150551] [PUBMED:14519398] [PUBMED:14556710] [PUBMED:11860281] [PUBMED:10664064] [PUBMED:9597126] [PUBMED:11050419] [PUBMED:12367625] [PUBMED:10798271] [PUBMED:16034094] [PUBMED:15115723] [PUBMED:15728677] [PUBMED:11910893] [PUBMED:15561584] [PUBMED:15882774] [PUBMED:12810109]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Cytokine-cytokine receptor interaction [NCBI:83051] [KEGG:hsa04060] [PUBMED:11071910] [PUBMED:12072446] [PUBMED:7791754] [PUBMED:15032600] [PUBMED:12651226] [PUBMED:11252892] [PUBMED:11796220] [PUBMED:11312110] [PUBMED:9862719] [PUBMED:12421671] [PUBMED:12039028] [PUBMED:9759503] [PUBMED:9395284] [PUBMED:11166270] [PUBMED:10714678] [PUBMED:12651221]
Epstein-Barr virus infection [NCBI:585562] [KEGG:hsa05169] [PUBMED:1658397] [PUBMED:10683340] [PUBMED:19375142] [PUBMED:12438576] [PUBMED:12910248] [PUBMED:10400785] [PUBMED:16007144] [PUBMED:14576817] [PUBMED:18559925] [PUBMED:16352731] [PUBMED:7895172] [PUBMED:15510157] [PUBMED:21518914] [PUBMED:10891508] [PUBMED:14673102] [PUBMED:17159145] [PUBMED:15542638] [PUBMED:18786993] [PUBMED:16603506] [PUBMED:10644367] [PUBMED:15021898] [PUBMED:10666279] [PUBMED:9565632]
HTLV-I infection [NCBI:373901] [KEGG:hsa05166] [PUBMED:17446673] [PUBMED:16436385] [PUBMED:14686485] [PUBMED:19861996] [PUBMED:19092975] [PUBMED:11325603] [PUBMED:16155602] [PUBMED:12910251] [PUBMED:16155605] [PUBMED:16036567] [PUBMED:11244044] [PUBMED:18702816] [PUBMED:15569630] [PUBMED:21114861] [PUBMED:16155611] [PUBMED:17384582] [PUBMED:16155608] [PUBMED:10602469] [PUBMED:19014483] [PUBMED:9325311]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell [NCBI:1269201] [REACTOME:R-HSA-198933] [PUBMED:17218381] [PUBMED:16603343] [PUBMED:16616474] [PUBMED:11244041] [PUBMED:16132082] [PUBMED:18425107]
Intestinal immune network for IgA production [NCBI:128760] [KEGG:hsa04672] [PUBMED:18483500] [PUBMED:18838301] [PUBMED:15971106] [PUBMED:18243016] [PUBMED:19079167] [PUBMED:18549797] [PUBMED:19079156] [PUBMED:17161619] [PUBMED:17182536] [PUBMED:12511876]
Malaria [NCBI:152665] [KEGG:hsa05144] [PUBMED:15106591] [PUBMED:11224682] [PUBMED:17630968] [PUBMED:18250459] [PUBMED:16138104] [PUBMED:20091081] [PUBMED:8920859] [PUBMED:19101208] [PUBMED:16019257] [PUBMED:15464448] [PUBMED:11832955] [PUBMED:12364790] [PUBMED:10885986] [PUBMED:15094163] [PUBMED:14737184] [PUBMED:15463497] [PUBMED:16468982] [PUBMED:19967139]
NF-kappa B signaling pathway [NCBI:634527] [KEGG:hsa04064] [PUBMED:22119011] [PUBMED:16264088] [PUBMED:21187855] [PUBMED:15546385] [PUBMED:17607554] [PUBMED:21135871] [PUBMED:16984817] [PUBMED:17047224] [PUBMED:19203223] [PUBMED:20300215] [PUBMED:14657271] [PUBMED:17431096] [PUBMED:15134788] [PUBMED:16356770] [PUBMED:21772278] [PUBMED:12654254] [PUBMED:22390971] [PUBMED:22017435] [PUBMED:17183360] [PUBMED:21173796] [PUBMED:15905862] [PUBMED:19302050] [PUBMED:17098202] [PUBMED:21872579] [PUBMED:22152226] [PUBMED:18613837] [PUBMED:19489733] [PUBMED:11875461] [PUBMED:19726767] [PUBMED:22017430] [PUBMED:21232019] [PUBMED:18832076]
Primary immunodeficiency [NCBI:83125] [KEGG:hsa05340] [PUBMED:11941303] [PUBMED:18093537] [PUBMED:11058677] [PUBMED:17952897] [PUBMED:14699405] [PUBMED:15661024] [PUBMED:14647478] [PUBMED:17960151] [PUBMED:16261175]
Systemic lupus erythematosus [NCBI:83122] [KEGG:hsa05322] [PUBMED:12835292] [PUBMED:12965173] [PUBMED:16932712] [PUBMED:10025913] [PUBMED:15972354] [PUBMED:17943287] [PUBMED:10430616] [PUBMED:18305268] [PUBMED:15380523] [PUBMED:8048228] [PUBMED:15459673]
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway [NCBI:1269330] [REACTOME:R-HSA-5676594] [PUBMED:18997794] [PUBMED:21173796] [PUBMED:22017430]
TNFR2 non-canonical NF-kB pathway [NCBI:1269329] [REACTOME:R-HSA-5668541] [PUBMED:19680262] [PUBMED:24298274] [PUBMED:21173796] [PUBMED:20489699] [PUBMED:24432023] [PUBMED:21232019] [PUBMED:22017430]
Toll-like receptor signaling pathway [NCBI:83076] [KEGG:hsa04620] [PUBMED:16924467] [PUBMED:17395581] [PUBMED:17637696] [PUBMED:12734364] [PUBMED:17507094] [PUBMED:14698224] [PUBMED:11101877] [PUBMED:16497588] [PUBMED:14751764] [PUBMED:17275323] [PUBMED:17457343] [PUBMED:16932750]
Toxoplasmosis [NCBI:169642] [KEGG:hsa05145] [PUBMED:18617274] [PUBMED:19400868] [PUBMED:17024357] [PUBMED:19744886] [PUBMED:19891610] [PUBMED:17110955] [PUBMED:12106793] [PUBMED:12580944] [PUBMED:12857995] [PUBMED:10234174] [PUBMED:18327664] [PUBMED:10525166] [PUBMED:18059289] [PUBMED:18775432] [PUBMED:14642303] [PUBMED:15361242] [PUBMED:16339966] [PUBMED:14987366] [PUBMED:15639739]
Transcriptional misregulation in cancer [NCBI:523016] [KEGG:hsa05202] [PUBMED:17327229] [PUBMED:20190806] [PUBMED:20145147] [PUBMED:11313274] [PUBMED:11863357] [PUBMED:19472090] [PUBMED:18330902] [PUBMED:19738075] [PUBMED:15024077] [PUBMED:12032780] [PUBMED:14630078] [PUBMED:21765642] [PUBMED:19564705] [PUBMED:17101797] [PUBMED:15160934] [PUBMED:15688424] [PUBMED:15985538] [PUBMED:12527902] [PUBMED:12511414] [PUBMED:11607818] [PUBMED:17222504] [PUBMED:15826838] [PUBMED:21747944] [PUBMED:19406209] [PUBMED:10350329] [PUBMED:21779514] [PUBMED:18563191] [PUBMED:16946003] [PUBMED:17250957] [PUBMED:12670461] [PUBMED:12529654] [PUBMED:18855877] [PUBMED:17505060] [PUBMED:20153925] [PUBMED:20490326] [PUBMED:12130514] [PUBMED:18648544] [PUBMED:19855079] [PUBMED:10717473] [PUBMED:20478527] [PUBMED:11340171] [PUBMED:16169901] [PUBMED:14998494] [PUBMED:19233641] [PUBMED:19133982] [PUBMED:12393465] [PUBMED:19059936] [PUBMED:18172298] [PUBMED:10500199] [PUBMED:19141473] [PUBMED:10537274] [PUBMED:15156184] [PUBMED:14701735] [PUBMED:19422821] [PUBMED:21518926] [PUBMED:18850010] [PUBMED:19075677] [PUBMED:18457914] [PUBMED:12527906] [PUBMED:15644444] [PUBMED:10784387] [PUBMED:17024155] [PUBMED:19075268] [PUBMED:15826834] [PUBMED:21849159] [PUBMED:21123453] [PUBMED:20974671] [PUBMED:20863376]
Viral myocarditis [NCBI:125138] [KEGG:hsa05416] [PUBMED:19357408] [PUBMED:18545064] [PUBMED:18357777] [PUBMED:11524405] [PUBMED:12920582] [PUBMED:14522402] [PUBMED:17200452] [PUBMED:18039131] [PUBMED:16413486] [PUBMED:12439638] [PUBMED:16817756] [PUBMED:16845885] [PUBMED:10051305] [PUBMED:10904843]