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Genes
NFATC2
Gene - NFATC2
full name
nuclear factor of activated T-cells 2
synonyms
NFAT1, NFATP, NFATC2, ENSG00000101096
HGNC
HGNC:7776
Entrez Gene
Gene:4773
ENSEMBL
ENSG00000101096
location
chr: 20
start: 50003494
stop: 50179370
strand: -
transcripts
NM_001258295.1
NM_001258294.1
NM_001258292.1
NM_001136021.2
NM_001258297.1
NM_001258296.1
NM_173091.3
NM_012340.4
pathways
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
B cell receptor signaling pathway
[NCBI:83081]
[KEGG:hsa04662]
[PUBMED:15626471]
[PUBMED:12119152]
[PUBMED:15886119]
[PUBMED:12461567]
[PUBMED:9697839]
[PUBMED:15752555]
[PUBMED:11163197]
[PUBMED:18086859]
[PUBMED:15364057]
[PUBMED:15457440]
[PUBMED:15322145]
[PUBMED:15771577]
[PUBMED:12033741]
[PUBMED:15886112]
[PUBMED:10358768]
C-type lectin receptors (CLRs)
[NCBI:1269303]
[REACTOME:R-HSA-5621481]
[PUBMED:19521399]
[PUBMED:24330199]
CLEC7A (Dectin-1) induces NFAT activation
[NCBI:1269305]
[REACTOME:R-HSA-5607763]
[PUBMED:17312158]
[PUBMED:22611159]
[PUBMED:21728173]
CLEC7A (Dectin-1) signaling
[NCBI:1269304]
[REACTOME:R-HSA-5607764]
[PUBMED:12719478]
[PUBMED:19223162]
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
[NCBI:137993]
[Pathway Interaction Database:nfat_tfpathway]
[PUBMED:11254715]
[PUBMED:11356833]
[PUBMED:12121669]
[PUBMED:10878360]
[PUBMED:11786533]
[PUBMED:8284217]
[PUBMED:10816557]
[PUBMED:11956291]
[PUBMED:7510691]
[PUBMED:9195954]
[PUBMED:8240350]
[PUBMED:12452838]
[PUBMED:8623163]
[PUBMED:15834410]
[PUBMED:10894164]
[PUBMED:10970869]
[PUBMED:10755616]
[PUBMED:14607827]
[PUBMED:12705856]
[PUBMED:12086671]
[PUBMED:7982959]
[PUBMED:9047239]
[PUBMED:12374808]
[PUBMED:14573767]
[PUBMED:12560487]
[PUBMED:10570264]
[PUBMED:8397339]
[PUBMED:12055628]
[PUBMED:15308098]
[PUBMED:12065418]
[PUBMED:7891702]
[PUBMED:7749982]
[PUBMED:14973438]
[PUBMED:8674125]
[PUBMED:16873067]
[PUBMED:12453415]
[PUBMED:8441422]
[PUBMED:1737937]
[PUBMED:10671476]
[PUBMED:8376940]
[PUBMED:9545284]
Calcium signaling in the CD4+ TCR pathway
[NCBI:137941]
[Pathway Interaction Database:tcrcalciumpathway]
[PUBMED:8284217]
[PUBMED:10816557]
[PUBMED:10970869]
[PUBMED:8240350]
[PUBMED:8623163]
[PUBMED:1715244]
[PUBMED:1715516]
[PUBMED:16406492]
[PUBMED:9655484]
[PUBMED:8397339]
[PUBMED:10861295]
[PUBMED:9047239]
[PUBMED:293720]
[PUBMED:7891702]
[PUBMED:12925851]
[PUBMED:9660798]
[PUBMED:1377362]
[PUBMED:12065418]
[PUBMED:8441422]
[PUBMED:7528941]
[PUBMED:1737937]
[PUBMED:12809556]
[PUBMED:9545284]
[PUBMED:11254715]
[PUBMED:10878360]
[PUBMED:10593895]
Downstream signaling in naive CD8+ T cells
[NCBI:138018]
[Pathway Interaction Database:cd8tcrdownstreampathway]
[PUBMED:293720]
[PUBMED:7935374]
[PUBMED:12065418]
[PUBMED:8566027]
[PUBMED:12917261]
[PUBMED:8394352]
[PUBMED:8441422]
[PUBMED:1386920]
[PUBMED:8617294]
[PUBMED:12732656]
[PUBMED:7889942]
[PUBMED:1737937]
[PUBMED:1381507]
[PUBMED:16210616]
[PUBMED:11927626]
[PUBMED:10477579]
[PUBMED:10206983]
[PUBMED:8376940]
[PUBMED:9395475]
[PUBMED:12972619]
[PUBMED:8394845]
[PUBMED:11485747]
[PUBMED:15814665]
[PUBMED:14645153]
[PUBMED:2119889]
[PUBMED:8208531]
[PUBMED:10970869]
[PUBMED:8612134]
[PUBMED:8623163]
[PUBMED:16237086]
[PUBMED:16585578]
[PUBMED:10544201]
[PUBMED:8397339]
[PUBMED:14605368]
[PUBMED:12560487]
[PUBMED:7982959]
FCERI mediated Ca+2 mobilization
[NCBI:1269300]
[REACTOME:R-HSA-2871809]
[PUBMED:17336609]
[PUBMED:10807788]
[PUBMED:1309940]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Fc-epsilon receptor I signaling in mast cells
[NCBI:138050]
[Pathway Interaction Database:fcer1pathway]
[PUBMED:9556577]
[PUBMED:8629002]
[PUBMED:12217401]
[PUBMED:15010370]
[PUBMED:15608142]
[PUBMED:7561053]
[PUBMED:7537741]
[PUBMED:7963537]
[PUBMED:8947047]
[PUBMED:1384468]
[PUBMED:14757742]
[PUBMED:16174756]
[PUBMED:10583594]
[PUBMED:7513150]
[PUBMED:12089510]
[PUBMED:10811803]
[PUBMED:9268346]
[PUBMED:12640123]
[PUBMED:9108083]
[PUBMED:8602265]
[PUBMED:11340169]
[PUBMED:12953098]
[PUBMED:11465115]
[PUBMED:7730640]
[PUBMED:9550384]
[PUBMED:7518558]
[PUBMED:11137136]
[PUBMED:15282299]
[PUBMED:14634134]
[PUBMED:8534912]
[PUBMED:16002993]
[PUBMED:12192036]
[PUBMED:7608202]
[PUBMED:11714805]
[PUBMED:11970986]
[PUBMED:10903718]
[PUBMED:15265912]
[PUBMED:15477350]
HTLV-I infection
[NCBI:373901]
[KEGG:hsa05166]
[PUBMED:17446673]
[PUBMED:16436385]
[PUBMED:14686485]
[PUBMED:19861996]
[PUBMED:19092975]
[PUBMED:11325603]
[PUBMED:16155602]
[PUBMED:12910251]
[PUBMED:16155605]
[PUBMED:16036567]
[PUBMED:11244044]
[PUBMED:18702816]
[PUBMED:15569630]
[PUBMED:21114861]
[PUBMED:16155611]
[PUBMED:17384582]
[PUBMED:16155608]
[PUBMED:10602469]
[PUBMED:19014483]
[PUBMED:9325311]
Hepatitis B
[NCBI:694606]
[KEGG:hsa05161]
[PUBMED:19854353]
[PUBMED:11604508]
[PUBMED:11325602]
[PUBMED:18931690]
[PUBMED:16891440]
[PUBMED:17158882]
[PUBMED:11099494]
[PUBMED:9325306]
[PUBMED:18024894]
[PUBMED:11483993]
[PUBMED:15107488]
[PUBMED:11278872]
[PUBMED:21647825]
[PUBMED:11287574]
[PUBMED:18481805]
[PUBMED:17188775]
[PUBMED:19784739]
[PUBMED:19263472]
[PUBMED:16203685]
[PUBMED:18605975]
[PUBMED:10454581]
[PUBMED:22504921]
[PUBMED:21334391]
[PUBMED:20657822]
[PUBMED:18046710]
[PUBMED:9843511]
[PUBMED:15542625]
[PUBMED:21618535]
[PUBMED:15132991]
[PUBMED:15173177]
[PUBMED:12771941]
[PUBMED:21994545]
[PUBMED:8764004]
[PUBMED:16459163]
[PUBMED:9738022]
[PUBMED:11821950]
[PUBMED:12839924]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Natural killer cell mediated cytotoxicity
[NCBI:83079]
[KEGG:hsa04650]
[PUBMED:12530970]
[PUBMED:15567854]
[PUBMED:8942070]
[PUBMED:11905813]
[PUBMED:9143705]
[PUBMED:9862693]
[PUBMED:11895890]
[PUBMED:12205470]
[PUBMED:11836514]
[PUBMED:15607806]
[PUBMED:16002670]
[PUBMED:15618404]
[PUBMED:11390470]
[PUBMED:11062493]
[PUBMED:14710949]
[PUBMED:12752668]
[PUBMED:15607802]
[PUBMED:16109839]
[PUBMED:12766758]
[PUBMED:16177799]
Noncanonical Wnt signaling pathway
[NCBI:169354]
[Pathway Interaction Database:wnt_noncanonical_pathway]
[PUBMED:11408485]
[PUBMED:20457807]
[PUBMED:17646398]
[PUBMED:15509575]
[PUBMED:10391247]
[PUBMED:12482967]
[PUBMED:10777564]
[PUBMED:19720827]
[PUBMED:18667433]
[PUBMED:18162551]
[PUBMED:18215320]
[PUBMED:17101698]
[PUBMED:12839624]
[PUBMED:19910923]
[PUBMED:10395542]
[PUBMED:15121866]
[PUBMED:11779461]
[PUBMED:16880514]
[PUBMED:18606138]
[PUBMED:12771126]
[PUBMED:18615587]
[PUBMED:17952062]
Osteoclast differentiation
[NCBI:193147]
[KEGG:hsa04380]
[PUBMED:17633024]
[PUBMED:18382763]
[PUBMED:18329366]
[PUBMED:17869613]
[PUBMED:18722561]
[PUBMED:15122243]
[PUBMED:20703218]
[PUBMED:12748652]
[PUBMED:12110142]
[PUBMED:19585227]
[PUBMED:15546140]
[PUBMED:16184196]
[PUBMED:15817678]
[PUBMED:20392226]
[PUBMED:16313349]
[PUBMED:16313342]
[PUBMED:17380158]
[PUBMED:18451259]
Oxytocin signaling pathway
[NCBI:952859]
[KEGG:hsa04921]
[PUBMED:23356278]
[PUBMED:9219843]
[PUBMED:20626426]
[PUBMED:18555543]
[PUBMED:22190926]
[PUBMED:21981277]
[PUBMED:9575824]
[PUBMED:22227279]
[PUBMED:19840865]
[PUBMED:11861513]
[PUBMED:9326674]
[PUBMED:12433531]
[PUBMED:18655881]
[PUBMED:23335873]
[PUBMED:22902539]
[PUBMED:16156781]
[PUBMED:20141572]
[PUBMED:14715914]
[PUBMED:12009385]
[PUBMED:16787565]
[PUBMED:16966388]
Role of Calcineurin-dependent NFAT signaling in lymphocytes
[NCBI:137953]
[Pathway Interaction Database:nfat_3pathway]
[PUBMED:15743762]
[PUBMED:9109491]
[PUBMED:1715244]
[PUBMED:15121840]
[PUBMED:10195903]
[PUBMED:10788511]
[PUBMED:9630228]
[PUBMED:9834092]
[PUBMED:9655484]
[PUBMED:10933397]
[PUBMED:11030334]
[PUBMED:8684469]
[PUBMED:10861295]
[PUBMED:15117942]
[PUBMED:12351631]
[PUBMED:15902271]
[PUBMED:16406492]
[PUBMED:10944115]
[PUBMED:10611249]
[PUBMED:15733859]
[PUBMED:15757646]
[PUBMED:9768749]
[PUBMED:9072970]
[PUBMED:12510191]
[PUBMED:9585406]
[PUBMED:293720]
[PUBMED:12925851]
[PUBMED:16943420]
[PUBMED:11823475]
[PUBMED:16141075]
[PUBMED:9374467]
[PUBMED:9660798]
[PUBMED:7528941]
[PUBMED:11356833]
[PUBMED:10593895]
[PUBMED:10866678]
[PUBMED:9171236]
[PUBMED:12809556]
[PUBMED:10652349]
[PUBMED:12021260]
[PUBMED:16455648]
T cell receptor signaling pathway
[NCBI:83080]
[KEGG:hsa04660]
[PUBMED:17395537]
[PUBMED:15308211]
[PUBMED:15928679]
[PUBMED:14656980]
[PUBMED:17187070]
[PUBMED:15084594]
[PUBMED:16799472]
[PUBMED:12669022]
[PUBMED:15286727]
[PUBMED:15122199]
[PUBMED:19132916]
[PUBMED:15489916]
[PUBMED:11905831]
[PUBMED:12195013]
[PUBMED:15343367]
[PUBMED:12133805]
[PUBMED:14647476]
[PUBMED:15771581]
[PUBMED:15099566]
[PUBMED:14617194]
[PUBMED:19290929]
[PUBMED:15345216]
Th1 and Th2 cell differentiation
[NCBI:1458885]
[KEGG:hsa04658]
[PUBMED:15819694]
[PUBMED:12171942]
[PUBMED:19165228]
[PUBMED:23336087]
[PUBMED:26044597]
[PUBMED:19151746]
[PUBMED:19362457]
[PUBMED:22044277]
[PUBMED:11752608]
[PUBMED:23405903]
[PUBMED:19375293]
[PUBMED:24113868]
[PUBMED:19151747]
[PUBMED:23624818]
[PUBMED:22566933]
[PUBMED:11121747]
[PUBMED:20969597]
[PUBMED:20065998]
Th17 cell differentiation
[NCBI:1469482]
[KEGG:hsa04659]
[PUBMED:23325835]
[PUBMED:23036716]
[PUBMED:20488727]
[PUBMED:21151104]
[PUBMED:21084214]
[PUBMED:20054607]
[PUBMED:22754770]
[PUBMED:22640807]
[PUBMED:19379825]
[PUBMED:22133865]
[PUBMED:22324470]
[PUBMED:17768419]
[PUBMED:18408735]
[PUBMED:21776333]
[PUBMED:26253381]
[PUBMED:16200068]
[PUBMED:18362914]
[PUBMED:24325586]
[PUBMED:19381306]
[PUBMED:18166487]
VEGF signaling pathway
[NCBI:83066]
[KEGG:hsa04370]
[PUBMED:11741095]
[PUBMED:16104843]
[PUBMED:14641020]
[PUBMED:15338053]
[PUBMED:14724572]
[PUBMED:12391145]
[PUBMED:13678960]
[PUBMED:15602010]
Validated transcriptional targets of AP1 family members Fra1 and Fra2
[NCBI:169349]
[Pathway Interaction Database:fra_pathway]
[PUBMED:20386569]
[PUBMED:1827665]
[PUBMED:17510314]
[PUBMED:17001307]
[PUBMED:19419315]
[PUBMED:12121977]
[PUBMED:15790882]
[PUBMED:18435914]
[PUBMED:1406676]
[PUBMED:20543861]
[PUBMED:19687301]
[PUBMED:9651314]
[PUBMED:20392257]
[PUBMED:20472895]
[PUBMED:16554298]
[PUBMED:17496887]
[PUBMED:19995753]
[PUBMED:8058317]
[PUBMED:2497053]
[PUBMED:8798756]
[PUBMED:17347653]
[PUBMED:18331200]
[PUBMED:19966854]
[PUBMED:17882273]
[PUBMED:9858556]
[PUBMED:3130660]
[PUBMED:19289495]
[PUBMED:11756554]
[PUBMED:1945831]
[PUBMED:15688012]
[PUBMED:8441422]
[PUBMED:17371847]
[PUBMED:10421804]
[PUBMED:2110368]
[PUBMED:18548006]
[PUBMED:20353950]
[PUBMED:15229648]
[PUBMED:11425864]
[PUBMED:15601844]
[PUBMED:10918580]
[PUBMED:9858557]
[PUBMED:19716794]
[PUBMED:9819396]
[PUBMED:17052890]
[PUBMED:20398633]
[PUBMED:20371606]
[PUBMED:10359014]
[PUBMED:15143165]
[PUBMED:15618352]
[PUBMED:9160889]
[PUBMED:12052899]
[PUBMED:9409785]
[PUBMED:15291758]
[PUBMED:1923525]
[PUBMED:7759510]
[PUBMED:15608675]
[PUBMED:14519134]
[PUBMED:20053986]
[PUBMED:15256456]
[PUBMED:19923172]
[PUBMED:15558021]
[PUBMED:12773579]
Wnt signaling pathway
[NCBI:83061]
[KEGG:hsa04310]
[PUBMED:12446114]
[PUBMED:14745971]
[PUBMED:14530294]
[PUBMED:15102436]
[PUBMED:14635791]
[PUBMED:19482104]
[PUBMED:23256519]
[PUBMED:12967557]
[PUBMED:11433294]
[PUBMED:18838381]
cGMP-PKG signaling pathway
[NCBI:983748]
[KEGG:hsa04022]
[PUBMED:18006449]
[PUBMED:9003029]
[PUBMED:18040025]
[PUBMED:19306895]
[PUBMED:21666108]
[PUBMED:12524221]
[PUBMED:16460276]
[PUBMED:20716671]
[PUBMED:22785374]
[PUBMED:11522789]
[PUBMED:16439998]
[PUBMED:16371594]
[PUBMED:20388537]
[PUBMED:18757523]
[PUBMED:16815627]
[PUBMED:23212367]
[PUBMED:21685243]
[PUBMED:20024580]
[PUBMED:15894227]
[PUBMED:22965426]
[PUBMED:17643091]
[PUBMED:19176601]
[PUBMED:19961855]