full name
cholinergic receptor nicotinic alpha 4 subunit

synonyms
BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4, CHRNA4, ENSG00000101204

HGNC
HGNC:1958

Entrez Gene
Gene:1137

ENSEMBL
ENSG00000101204

location
chr: 20
start: 61974662
stop: 62009487
strand: -

OMIM
OMIM:118504: CHRNA4 (Autosomal dominant inheritance)
OMIM:600513: Epilepsy, nocturnal frontal lobe, 1
OMIM:188890: {Nicotine addiction, susceptibility to}

transcripts
NM_001256573.1
NM_000744.6
NR_046317.1

pathways
Acetylcholine Binding And Downstream Events [NCBI:1268787] [REACTOME:R-HSA-181431]
Activation of Nicotinic Acetylcholine Receptors [NCBI:1268788] [REACTOME:R-HSA-629602] [PUBMED:19126755] [PUBMED:11532443] [PUBMED:18691557] [PUBMED:19481063]
Cholinergic synapse [NCBI:217716] [KEGG:hsa04725] [PUBMED:20060019] [PUBMED:11283752] [PUBMED:15165747] [PUBMED:12893537] [PUBMED:11738031] [PUBMED:21550798] [PUBMED:19712465] [PUBMED:12690458] [PUBMED:12436417] [PUBMED:19378880] [PUBMED:11923408] [PUBMED:20446119]
Highly calcium permeable nicotinic acetylcholine receptors [NCBI:1268790] [REACTOME:R-HSA-629597] [PUBMED:14670366]
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [NCBI:1268793] [REACTOME:R-HSA-629594] [PUBMED:14670366]
Highly sodium permeable acetylcholine nicotinic receptors [NCBI:1268791] [REACTOME:R-HSA-629587] [PUBMED:9110108]
Neuroactive ligand-receptor interaction [NCBI:83053] [KEGG:hsa04080]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell [NCBI:1268786] [REACTOME:R-HSA-112314]
Nicotine addiction [NCBI:583255] [KEGG:hsa05033] [PUBMED:19498417] [PUBMED:15661626] [PUBMED:12436424] [PUBMED:19669944] [PUBMED:19434058] [PUBMED:19184650] [PUBMED:15165747] [PUBMED:12716925] [PUBMED:18723034] [PUBMED:18640919] [PUBMED:11906697] [PUBMED:14708004] [PUBMED:17009926] [PUBMED:14747518] [PUBMED:20485364] [PUBMED:16251989] [PUBMED:20833261]
Postsynaptic nicotinic acetylcholine receptors [NCBI:1268792] [REACTOME:R-HSA-622327] [PUBMED:17689497] [PUBMED:12036180] [PUBMED:17009926]
Presynaptic nicotinic acetylcholine receptors [NCBI:1268789] [REACTOME:R-HSA-622323] [PUBMED:9023878]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]