full name
helicase with zinc finger 2

synonyms
PDIP-1, PRIC285, HELZ2, ENSG00000130589

HGNC
HGNC:30021

Entrez Gene
Gene:85441

ENSEMBL
ENSG00000130589

location
chr: 20
start: 62189439
stop: 62205592
strand: -

transcripts
NM_001037335.2
NM_033405.3

pathways
Activation of gene expression by SREBF (SREBP) [NCBI:1270039] [REACTOME:R-HSA-2426168] [PUBMED:15589694] [PUBMED:9748295] [PUBMED:15457548]
BMAL1:CLOCK,NPAS2 activates circadian gene expression [NCBI:1269872] [REACTOME:R-HSA-1368108] [PUBMED:12868535] [PUBMED:9616112]
Circadian Clock [NCBI:1269871] [REACTOME:R-HSA-400253] [PUBMED:18775307] [PUBMED:18802415] [PUBMED:18786386] [PUBMED:16987893]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Mitochondrial biogenesis [NCBI:1268839] [REACTOME:R-HSA-1592230] [PUBMED:18430751] [PUBMED:19262508] [PUBMED:22265687] [PUBMED:20533901] [PUBMED:20933024] [PUBMED:21757760] [PUBMED:19575678] [PUBMED:19008463] [PUBMED:21629705] [PUBMED:21543634] [PUBMED:22817841] [PUBMED:20649548] [PUBMED:22146081] [PUBMED:19276888] [PUBMED:19682549] [PUBMED:15744310] [PUBMED:19076454]
Organelle biogenesis and maintenance [NCBI:1268838] [REACTOME:R-HSA-1852241] [PUBMED:8608592] [PUBMED:16103713]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
RORA activates gene expression [NCBI:1269873] [REACTOME:R-HSA-1368082] [PUBMED:7926749]
Regulation of cholesterol biosynthesis by SREBP (SREBF) [NCBI:1270038] [REACTOME:R-HSA-1655829] [PUBMED:15457548] [PUBMED:19933148] [PUBMED:18974038]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
Transcriptional activation of mitochondrial biogenesis [NCBI:1268841] [REACTOME:R-HSA-2151201] [PUBMED:22265687] [PUBMED:20933024] [PUBMED:19575678] [PUBMED:22817841] [PUBMED:19682549]
Transcriptional regulation of white adipocyte differentiation [NCBI:1270345] [REACTOME:R-HSA-381340] [PUBMED:21082419] [PUBMED:17956727] [PUBMED:17475546] [PUBMED:1840554] [PUBMED:17139329] [PUBMED:15860371] [PUBMED:18518822] [PUBMED:10603305] [PUBMED:7531665] [PUBMED:20054179] [PUBMED:7838715] [PUBMED:16054042] [PUBMED:17060461] [PUBMED:17011499] [PUBMED:16380219] [PUBMED:8970730]
YAP1- and WWTR1 (TAZ)-stimulated gene expression [NCBI:1269653] [REACTOME:R-HSA-2032785] [PUBMED:16332960] [PUBMED:20452772]