Logo
full name
ryanodine receptor 2

synonyms
ARVC2, ARVD2, RyR, RYR-2, VTSIP, RYR2, ENSG00000198626

HGNC
HGNC:10484

Entrez Gene
Gene:6262

ENSEMBL
ENSG00000198626

location
chr: 1
start: 237205510
stop: 237997288
strand: +

OMIM
OMIM:180902: RYR2
OMIM:600996: Arrhythmogenic right ventricular dysplasia 2
OMIM:604772: Ventricular tachycardia, catecholaminergic polymorphic, 1

transcripts
NM_001035.2

pathways
Adrenergic signaling in cardiomyocytes [NCBI:908257] [KEGG:hsa04261] [PUBMED:15232578] [PUBMED:11604549] [PUBMED:20923637] [PUBMED:10571541] [PUBMED:17988210] [PUBMED:11805843] [PUBMED:15142747] [PUBMED:21212391] [PUBMED:20658186] [PUBMED:19874988] [PUBMED:19883653] [PUBMED:22022314] [PUBMED:17826821] [PUBMED:15765137] [PUBMED:16765984] [PUBMED:15979723] [PUBMED:18407781] [PUBMED:12439640]
Arrhythmogenic right ventricular cardiomyopathy [NCBI:672454] [WikiPathways:WP2118]
Arrhythmogenic right ventricular cardiomyopathy (ARVC) [NCBI:117293] [KEGG:hsa05412] [PUBMED:16823481] [PUBMED:19205777] [PUBMED:11716909] [PUBMED:12270949] [PUBMED:18382419] [PUBMED:16101641] [PUBMED:17413274] [PUBMED:16124859]
Calcium Regulation in the Cardiac Cell [NCBI:198906] [WikiPathways:WP536] [PUBMED:12618512]
Calcium signaling pathway [NCBI:83050] [KEGG:hsa04020] [PUBMED:11080247] [PUBMED:11413485] [PUBMED:10508738] [PUBMED:14572802] [PUBMED:15000521] [PUBMED:22129055] [PUBMED:7861177] [PUBMED:9149541] [PUBMED:9235901] [PUBMED:10331643] [PUBMED:11698232] [PUBMED:15111104] [PUBMED:12838335] [PUBMED:10997573] [PUBMED:19172794] [PUBMED:12972622] [PUBMED:21338471] [PUBMED:22002090] [PUBMED:11299192] [PUBMED:14517314] [PUBMED:8125957]
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:26140724] [PUBMED:21357845] [PUBMED:19808464]
Cardiac muscle contraction [NCBI:93344] [KEGG:hsa04260] [PUBMED:16799263] [PUBMED:16552170] [PUBMED:15736582] [PUBMED:14659803] [PUBMED:17988210] [PUBMED:10747208] [PUBMED:11294886] [PUBMED:18981594] [PUBMED:12763850] [PUBMED:16096350] [PUBMED:11805843] [PUBMED:16701909]
Circadian entrainment [NCBI:698773] [KEGG:hsa04713] [PUBMED:15016477] [PUBMED:15813931] [PUBMED:15930378] [PUBMED:12573527] [PUBMED:20664079] [PUBMED:17586087] [PUBMED:11294753] [PUBMED:17646042] [PUBMED:10446325] [PUBMED:17167088] [PUBMED:19109992] [PUBMED:16217123] [PUBMED:19449447] [PUBMED:10208575] [PUBMED:11086993] [PUBMED:12700026] [PUBMED:20605968]
Dilated cardiomyopathy [NCBI:121494] [KEGG:hsa05414] [PUBMED:11524405] [PUBMED:11805847] [PUBMED:12270949] [PUBMED:15146239] [PUBMED:18672201] [PUBMED:14522402] [PUBMED:19017683] [PUBMED:19273156] [PUBMED:19246813] [PUBMED:11716909] [PUBMED:16817756]
Hypertrophic cardiomyopathy (HCM) [NCBI:114229] [KEGG:hsa05410] [PUBMED:18572189] [PUBMED:11805847] [PUBMED:14711353] [PUBMED:19136482] [PUBMED:18056765] [PUBMED:11225594] [PUBMED:10615904] [PUBMED:12844200] [PUBMED:11716909] [PUBMED:11371514] [PUBMED:12270949]
Insulin secretion [NCBI:777534] [KEGG:hsa04911] [PUBMED:9715374] [PUBMED:20055708] [PUBMED:10605628] [PUBMED:17306374] [PUBMED:9914469] [PUBMED:14693691] [PUBMED:19817784] [PUBMED:19074620] [PUBMED:15655710] [PUBMED:17084085] [PUBMED:20551594] [PUBMED:19036624] [PUBMED:22970724] [PUBMED:20225132] [PUBMED:22974438] [PUBMED:19817800] [PUBMED:21934040] [PUBMED:15271645] [PUBMED:19660440] [PUBMED:11522660]
Ion channel transport [NCBI:1269950] [REACTOME:R-HSA-983712] [PUBMED:15071553]
Ion homeostasis [NCBI:1339121] [REACTOME:R-HSA-5578775] [PUBMED:26140724] [PUBMED:17017901]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Myometrial Relaxation and Contraction Pathways [NCBI:198759] [WikiPathways:WP289] [PUBMED:11701706] [PUBMED:11854458] [PUBMED:15693941]
Oxytocin signaling pathway [NCBI:952859] [KEGG:hsa04921] [PUBMED:9219843] [PUBMED:23356278] [PUBMED:20626426] [PUBMED:21981277] [PUBMED:9575824] [PUBMED:22227279] [PUBMED:11861513] [PUBMED:22190926] [PUBMED:19840865] [PUBMED:12433531] [PUBMED:18655881] [PUBMED:14715914] [PUBMED:16156781] [PUBMED:20141572] [PUBMED:16787565] [PUBMED:22902539] [PUBMED:16966388] [PUBMED:12009385] [PUBMED:18555543] [PUBMED:9326674] [PUBMED:23335873]
Pancreatic secretion [NCBI:169306] [KEGG:hsa04972] [PUBMED:9548666] [PUBMED:16888148] [PUBMED:20224219] [PUBMED:19088252] [PUBMED:15689674] [PUBMED:10835353] [PUBMED:15709963] [PUBMED:14660554] [PUBMED:10078532] [PUBMED:20625287] [PUBMED:16930743] [PUBMED:14637169] [PUBMED:17850212] [PUBMED:18626068] [PUBMED:16891880] [PUBMED:11087843] [PUBMED:17205399]
SIDS Susceptibility Pathways [NCBI:198901] [WikiPathways:WP706] [PUBMED:21836131] [PUBMED:16275016] [PUBMED:18571009] [PUBMED:18633768] [PUBMED:19958302] [PUBMED:20009079] [PUBMED:16846370] [PUBMED:16006741] [PUBMED:19772970] [PUBMED:19120039] [PUBMED:19278673] [PUBMED:7908738] [PUBMED:17142880] [PUBMED:16764822] [PUBMED:17311278] [PUBMED:10575032] [PUBMED:19342987] [PUBMED:18032528] [PUBMED:22179534] [PUBMED:18041756] [PUBMED:18085326] [PUBMED:17568567] [PUBMED:11080175] [PUBMED:21204411] [PUBMED:16938762] [PUBMED:22226696] [PUBMED:19880519] [PUBMED:20847275] [PUBMED:22418790] [PUBMED:2058745] [PUBMED:17869437] [PUBMED:9676432] [PUBMED:18384375] [PUBMED:17556193] [PUBMED:15199055] [PUBMED:8841406] [PUBMED:16916793] [PUBMED:18286597] [PUBMED:15056938] [PUBMED:15584216] [PUBMED:20351659] [PUBMED:9645961] [PUBMED:18792810] [PUBMED:15758173] [PUBMED:14693395] [PUBMED:7745608] [PUBMED:19559077] [PUBMED:19841066] [PUBMED:12599191] [PUBMED:17077377] [PUBMED:18675942] [PUBMED:18234890] [PUBMED:16144830] [PUBMED:18778441] [PUBMED:8957963] [PUBMED:22371606] [PUBMED:20124538] [PUBMED:9038229] [PUBMED:21555452] [PUBMED:21865888] [PUBMED:12393272] [PUBMED:22351881] [PUBMED:12065627] [PUBMED:17101276] [PUBMED:16830328] [PUBMED:10421804] [PUBMED:14575242] [PUBMED:9933599] [PUBMED:18599790] [PUBMED:11335745] [PUBMED:19396608] [PUBMED:18639564] [PUBMED:10197817] [PUBMED:14608012] [PUBMED:18771483] [PUBMED:18045290] [PUBMED:18094064] [PUBMED:16467535] [PUBMED:18192214] [PUBMED:19247214] [PUBMED:9602135] [PUBMED:20209124] [PUBMED:16728402] [PUBMED:10094440] [PUBMED:17613521] [PUBMED:18534229] [PUBMED:17709376] [PUBMED:17360901] [PUBMED:18928334] [PUBMED:19666841] [PUBMED:14741405] [PUBMED:22334710] [PUBMED:14756806] [PUBMED:19369586] [PUBMED:15240857] [PUBMED:18810510] [PUBMED:17597646]
Stimuli-sensing channels [NCBI:1269953] [REACTOME:R-HSA-2672351] [PUBMED:15728426] [PUBMED:16460286] [PUBMED:22934072] [PUBMED:18391176] [PUBMED:11904445] [PUBMED:19278523] [PUBMED:20807551] [PUBMED:22277752] [PUBMED:19783045] [PUBMED:21932071] [PUBMED:16219661] [PUBMED:12907679]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
cAMP signaling pathway [NCBI:1017634] [KEGG:hsa04024] [PUBMED:9204709] [PUBMED:21693691] [PUBMED:21744067] [PUBMED:21346730] [PUBMED:24062645] [PUBMED:18176800] [PUBMED:24450633] [PUBMED:22082266] [PUBMED:16460276] [PUBMED:16765984] [PUBMED:14715909] [PUBMED:7688165] [PUBMED:18064650] [PUBMED:11117527] [PUBMED:24281338] [PUBMED:11493633] [PUBMED:21852968] [PUBMED:15142747] [PUBMED:21212391] [PUBMED:19874988] [PUBMED:17077866] [PUBMED:22022314] [PUBMED:16571352] [PUBMED:10880354] [PUBMED:24613710] [PUBMED:18323530] [PUBMED:19460777]