full name
ubiquitin specific peptidase 18

synonyms
ISG43, UBP43, USP18, ENSG00000184979

HGNC
HGNC:12616

Entrez Gene
Gene:11274

ENSEMBL
ENSG00000184979

location
chr: 22
start: 18632758
stop: 18660164
strand: +

OMIM
OMIM:607057: USP18
OMIM:617397: Pseudo-TORCH syndrome 2

transcripts
NM_017414.3

pathways
Antiviral mechanism by IFN-stimulated genes [NCBI:1269316] [REACTOME:R-HSA-1169410]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Deubiquitination [NCBI:1427860] [REACTOME:R-HSA-5688426] [PUBMED:19243136] [PUBMED:20074029] [PUBMED:15571815] [PUBMED:20418328] [PUBMED:16325574] [PUBMED:12944365] [PUBMED:23845989] [PUBMED:22201797]
ISG15 antiviral mechanism [NCBI:1269317] [REACTOME:R-HSA-1169408] [PUBMED:20153823] [PUBMED:12582176] [PUBMED:16009940] [PUBMED:20946978] [PUBMED:15970528]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Interferon Signaling [NCBI:1269311] [REACTOME:R-HSA-913531] [PUBMED:18929502] [PUBMED:15607020] [PUBMED:15864272] [PUBMED:14525967] [PUBMED:19059436]
Interferon alpha/beta signaling [NCBI:1269312] [REACTOME:R-HSA-909733] [PUBMED:8621447] [PUBMED:8605876] [PUBMED:8702790] [PUBMED:17969444]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Regulation of IFNA signaling [NCBI:1269313] [REACTOME:R-HSA-912694] [PUBMED:16710296] [PUBMED:16311601] [PUBMED:10526574]
Ub-specific processing proteases [NCBI:1427862] [REACTOME:R-HSA-5689880] [PUBMED:16325574]