full name
X-box binding protein 1

synonyms
TREB5, XBP-1, XBP2, XBP1, ENSG00000100219

HGNC
HGNC:12801

Entrez Gene
Gene:7494

ENSEMBL
ENSG00000100219

location
chr: 22
start: 29190548
stop: 29196560
strand: -

OMIM
OMIM:194355: XBP1
OMIM:612371: {Major affective disorder-7, susceptibility to}

transcripts
NM_001079539.1
NM_005080.3

pathways
ATF6 (ATF6-alpha) activates chaperone genes [NCBI:1268758] [REACTOME:R-HSA-381183] [PUBMED:10866666] [PUBMED:14973138] [PUBMED:12014989] [PUBMED:25821458] [PUBMED:10856300] [PUBMED:10958673]
ATF6 (ATF6-alpha) activates chaperones [NCBI:1268757] [REACTOME:R-HSA-381033] [PUBMED:25821458] [PUBMED:18048764] [PUBMED:18038217] [PUBMED:18436705]
FOXA1 transcription factor network [NCBI:137979] [Pathway Interaction Database:hnf3apathway] [PUBMED:9427758] [PUBMED:16087863] [PUBMED:12750453] [PUBMED:12441652] [PUBMED:11763995] [PUBMED:8441395] [PUBMED:8164696] [PUBMED:2786140] [PUBMED:8071346] [PUBMED:8598458] [PUBMED:16331276] [PUBMED:16214823] [PUBMED:10049364] [PUBMED:15987773] [PUBMED:10073575] [PUBMED:8058060] [PUBMED:16980581] [PUBMED:9685261] [PUBMED:16009131]
HTLV-I infection [NCBI:373901] [KEGG:hsa05166] [PUBMED:17446673] [PUBMED:16436385] [PUBMED:14686485] [PUBMED:19861996] [PUBMED:19092975] [PUBMED:11325603] [PUBMED:16155602] [PUBMED:12910251] [PUBMED:16155605] [PUBMED:16036567] [PUBMED:11244044] [PUBMED:18702816] [PUBMED:15569630] [PUBMED:21114861] [PUBMED:16155611] [PUBMED:17384582] [PUBMED:16155608] [PUBMED:10602469] [PUBMED:19014483] [PUBMED:9325311]
IRE1alpha activates chaperones [NCBI:1268759] [REACTOME:R-HSA-381070] [PUBMED:18048764] [PUBMED:18038217] [PUBMED:18436705]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Non-alcoholic fatty liver disease (NAFLD) [NCBI:862188] [KEGG:hsa04932] [PUBMED:21038418] [PUBMED:17498512] [PUBMED:19352614] [PUBMED:23299992] [PUBMED:22570745] [PUBMED:9285483] [PUBMED:12891546] [PUBMED:18061659] [PUBMED:22705006] [PUBMED:16364488] [PUBMED:18242193] [PUBMED:16374858] [PUBMED:22940046] [PUBMED:20619513] [PUBMED:20303879] [PUBMED:14685853] [PUBMED:16406828] [PUBMED:23545492] [PUBMED:21145844]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:20219571] [PUBMED:19491040] [PUBMED:20112977]
Unfolded Protein Response (UPR) [NCBI:1268756] [REACTOME:R-HSA-381119] [PUBMED:18436705] [PUBMED:18038217] [PUBMED:27067637] [PUBMED:16365312] [PUBMED:18048764] [PUBMED:15952902]
XBP1(S) activates chaperone genes [NCBI:1268760] [REACTOME:R-HSA-381038] [PUBMED:16461360] [PUBMED:16539657] [PUBMED:17612490] [PUBMED:14559994] [PUBMED:18664523]