full name
eukaryotic translation initiation factor 3 subunit L

synonyms
EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025, MSTP005, EIF3L, ENSG00000100129

HGNC
HGNC:18138

Entrez Gene
Gene:51386

ENSEMBL
ENSG00000100129

location
chr: 22
start: 38245379
stop: 38284789
strand: +

transcripts
NM_016091.3
NM_001242923.1

pathways
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S [NCBI:1268683] [REACTOME:R-HSA-72662] [PUBMED:9732867] [PUBMED:592399] [PUBMED:641056] [PUBMED:6853548]
Cap-dependent Translation Initiation [NCBI:1268680] [REACTOME:R-HSA-72737]
Eukaryotic Translation Initiation [NCBI:1268679] [REACTOME:R-HSA-72613] [PUBMED:20444697]
Formation of a pool of free 40S subunits [NCBI:1268681] [REACTOME:R-HSA-72689]
Formation of the ternary complex, and subsequently, the 43S complex [NCBI:1268682] [REACTOME:R-HSA-72695] [PUBMED:641056] [PUBMED:1104615] [PUBMED:592399] [PUBMED:429297]
GTP hydrolysis and joining of the 60S ribosomal subunit [NCBI:1268686] [REACTOME:R-HSA-72706] [PUBMED:11018020] [PUBMED:1095581] [PUBMED:429297] [PUBMED:641056] [PUBMED:1856230] [PUBMED:592398] [PUBMED:10659855] [PUBMED:592399]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
L13a-mediated translational silencing of Ceruloplasmin expression [NCBI:1268688] [REACTOME:R-HSA-156827] [PUBMED:14567916]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Ribosomal scanning and start codon recognition [NCBI:1268685] [REACTOME:R-HSA-72702] [PUBMED:9732867] [PUBMED:7000367] [PUBMED:592399] [PUBMED:641056]
Translation [NCBI:1268678] [REACTOME:R-HSA-72766]
Translation initiation complex formation [NCBI:1268684] [REACTOME:R-HSA-72649] [PUBMED:6853548] [PUBMED:641056] [PUBMED:9732867] [PUBMED:592399]