full name
thymidine phosphorylase

synonyms
ECGF, ECGF1, hPD-ECGF, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, TYMP, ENSG00000025708

HGNC
HGNC:3148

Entrez Gene
Gene:1890

ENSEMBL
ENSG00000025708

location
chr: 22
start: 50964181
stop: 50968514
strand: -

OMIM
OMIM:131222: TYMP (Autosomal recessive inheritance)
OMIM:603041: Mitochondrial DNA depletion syndrome 1 (MNGIE type)

transcripts
NM_001953.4
NM_001257989.1
NM_001113755.2
NM_001257988.1
NM_001113756.2

pathways
Bladder cancer [NCBI:83115] [KEGG:hsa05219] [PUBMED:15551095] [PUBMED:15746962] [PUBMED:11103787] [PUBMED:16474624] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:17149381] [PUBMED:16110317]
Drug metabolism - other enzymes [NCBI:83033] [KEGG:hsa00983] [PUBMED:15514566] [PUBMED:15173095] [PUBMED:15788214] [PUBMED:11379777] [PUBMED:10976516] [PUBMED:11489791] [PUBMED:16048561] [PUBMED:16880012]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of nucleotides [NCBI:1270133] [REACTOME:R-HSA-15869] [PUBMED:17266529] [PUBMED:8283301] [PUBMED:20494131]
Pyrimidine catabolism [NCBI:1270141] [REACTOME:R-HSA-73621] [PUBMED:3090932] [PUBMED:10989446]
Pyrimidine metabolism [NCBI:82946] [KEGG:hsa00240] [NCBI:1270138] [REACTOME:R-HSA-73848] [PUBMED:16098809]
Pyrimidine salvage reactions [NCBI:1270140] [REACTOME:R-HSA-73614]
pyrimidine deoxyribonucleosides degradation [NCBI:782401] [BIOCYC:HUMAN_PWY-7181]