full name
Cdc42 guanine nucleotide exchange factor 9

synonyms
COLLYBISTIN, EIEE8, HPEM-2, PEM-2, PEM2, ARHGEF9, ENSG00000131089

HGNC
HGNC:14561

Entrez Gene
Gene:23229

ENSEMBL
ENSG00000131089
ENSG00000268229

location
chr: X
start: 62854847
stop: 63005426
strand: -

OMIM
OMIM:300429: ARHGEF9 (X-linked recessive inheritance)
OMIM:300607: Epileptic encephalopathy, early infantile, 8

transcripts
NM_001173479.1
NM_001173480.1
NM_015185.2

pathways
Cell death signalling via NRAGE, NRIF and NADE [NCBI:1269447] [REACTOME:R-HSA-204998] [PUBMED:12787561]
G alpha (12/13) signalling events [NCBI:1269579] [REACTOME:R-HSA-416482] [PUBMED:18814923] [PUBMED:19212140]
GABA A receptor activation [NCBI:1268814] [REACTOME:R-HSA-977441] [PUBMED:19828786] [PUBMED:17364682] [PUBMED:18382465]
GABA receptor activation [NCBI:1268813] [REACTOME:R-HSA-977443] [PUBMED:17364682] [PUBMED:20655481] [PUBMED:11283747] [PUBMED:20655485] [PUBMED:15269338]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
Ion channel transport [NCBI:1269950] [REACTOME:R-HSA-983712] [PUBMED:15071553]
Ligand-gated ion channel transport [NCBI:1269952] [REACTOME:R-HSA-975298]
NRAGE signals death through JNK [NCBI:1269448] [REACTOME:R-HSA-193648] [PUBMED:12376548]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell [NCBI:1268786] [REACTOME:R-HSA-112314]
Regulation of CDC42 activity [NCBI:137990] [Pathway Interaction Database:cdc42_reg_pathway] [PUBMED:19581296] [PUBMED:17297291] [PUBMED:14506234] [PUBMED:17145773] [PUBMED:8798610] [PUBMED:17015620] [PUBMED:9535855] [PUBMED:15710388] [PUBMED:12547822] [PUBMED:15728722] [PUBMED:11285260] [PUBMED:11748279] [PUBMED:8969170] [PUBMED:17538024] [PUBMED:11336673] [PUBMED:12172552] [PUBMED:15850391] [PUBMED:18208356] [PUBMED:10523665] [PUBMED:1429634] [PUBMED:19156867] [PUBMED:19356586] [PUBMED:16616186] [PUBMED:15247287] [PUBMED:9497316] [PUBMED:10559246] [PUBMED:14506284] [PUBMED:16892055] [PUBMED:19525225] [PUBMED:11741931] [PUBMED:17562871] [PUBMED:18470881] [PUBMED:1439791] [PUBMED:10744696] [PUBMED:7673236] [PUBMED:12432077] [PUBMED:17196961] [PUBMED:10982832] [PUBMED:16968698] [PUBMED:11431473] [PUBMED:10676816] [PUBMED:15277544] [PUBMED:18728402] [PUBMED:15793564] [PUBMED:18056264] [PUBMED:9268338] [PUBMED:12517963] [PUBMED:1956381] [PUBMED:15504743] [PUBMED:17599059] [PUBMED:15649357] [PUBMED:10652228] [PUBMED:15306850] [PUBMED:19745154]
Rho GTPase cycle [NCBI:1269508] [REACTOME:R-HSA-194840] [PUBMED:17222083] [PUBMED:9308960]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]
p75 NTR receptor-mediated signalling [NCBI:1269445] [REACTOME:R-HSA-193704] [PUBMED:16699811] [PUBMED:16939974] [PUBMED:12671646]