full name
discs large MAGUK scaffold protein 3

synonyms
MRX, MRX90, NEDLG, SAP102, XLMR, DLG3, ENSG00000082458

HGNC
HGNC:2902

Entrez Gene
Gene:1741

ENSEMBL
ENSG00000082458

location
chr: X
start: 69664705
stop: 69725343
strand: +

OMIM
OMIM:300189: DLG3 (X-linked inheritance)
OMIM:300850: Mental retardation, X-linked 90

transcripts
NM_021120.3
NM_020730.2
NM_001166278.1

pathways
Activation of Ca-permeable Kainate Receptor [NCBI:1268811] [REACTOME:R-HSA-451308] [PUBMED:10718099]
Activation of Kainate Receptors upon glutamate binding [NCBI:1268808] [REACTOME:R-HSA-451326] [PUBMED:18793656]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Hippo signaling pathway [NCBI:749777] [KEGG:hsa04390] [PUBMED:18955139] [PUBMED:20439427] [PUBMED:20951342] [PUBMED:21138973] [PUBMED:18328423] [PUBMED:21324984] [PUBMED:23034192] [PUBMED:21808241] [PUBMED:17975546] [PUBMED:22750148] [PUBMED:21084559] [PUBMED:19846288] [PUBMED:22895435] [PUBMED:22683405] [PUBMED:22658639] [PUBMED:22153608] [PUBMED:20945341] [PUBMED:22830020] [PUBMED:21874053] [PUBMED:21376238]
Interactions of neurexins and neuroligins at synapses [NCBI:1427850] [REACTOME:R-HSA-6794361] [PUBMED:22424845] [PUBMED:23559421] [PUBMED:21155806] [PUBMED:17299456] [PUBMED:17275284]
Ionotropic activity of Kainate Receptors [NCBI:1268809] [REACTOME:R-HSA-451306] [PUBMED:16847640]
L1CAM interactions [NCBI:1270323] [REACTOME:R-HSA-373760] [PUBMED:9211984] [PUBMED:18760361] [PUBMED:14709786] [PUBMED:17189949] [PUBMED:19356150]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell [NCBI:1268786] [REACTOME:R-HSA-112314]
NrCAM interactions [NCBI:1270329] [REACTOME:R-HSA-447038] [PUBMED:10662501] [PUBMED:19356150] [PUBMED:16202709]
Protein-protein interactions at synapses [NCBI:1427849] [REACTOME:R-HSA-6794362] [PUBMED:18923512] [PUBMED:16337696] [PUBMED:17299456]
SALM protein interactions at the synapses [NCBI:1383059] [REACTOME:R-HSA-8849932] [PUBMED:22046028] [PUBMED:16630835] [PUBMED:21736948]
Tight junction [NCBI:83071] [KEGG:hsa04530] [PUBMED:25152334] [PUBMED:16650994] [PUBMED:22892070] [PUBMED:18946474] [PUBMED:12042308] [PUBMED:23885123] [PUBMED:16771626] [PUBMED:17182900] [PUBMED:21283798] [PUBMED:25757376] [PUBMED:22928510] [PUBMED:22169974] [PUBMED:25469537] [PUBMED:24651541] [PUBMED:15820555] [PUBMED:17525755] [PUBMED:27353478] [PUBMED:17950242] [PUBMED:18005931] [PUBMED:24548561] [PUBMED:21781017] [PUBMED:20094051] [PUBMED:20134025] [PUBMED:22896795] [PUBMED:18094055] [PUBMED:25483301]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]